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1. 发明申请

US20140324142A1 ACUTE MYOCARDIAL INFARCTION TREATMENT BY ELECTRICAL STIMULATION OF THE THORACIC AORTA 审中-公开
标题翻译：通过电刺激胸腔积液治疗急性心肌梗塞
公开(公告)号：US20140324142A1
公开(公告)日：2014-10-30
申请号：US14356829
申请日：2012-11-08
申请人： ENOPACE BIOMEDICAL LTD.
发明人： Amir Dagan , Offer Glasberg , Yotam Reisner , Gal Ariav , Nitai Hanani
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0558 , A61N1/36017 , A61N1/36114
摘要： Apparatus and methods are described including an electrode device (30) that is configured to assume a coiled configuration when the device is in an unconstrained state, the electrode device being shaped to define a lumen (40). At least one electrode (21) is disposed on the electrode device. At least one electrical wire (32) is coupled to the electrode. A flexible lead (34) defines a lumen (42) therethrough, the electrical wire being housed inside the lead. A stylet (36) constrains the electrode device into a straightened configuration by being inserted into the lumen defined by the electrode device. The stylet additionally stiffens the flexible lead by being inserted into the lumen defined by the flexible lead. Other applications are also described.
摘要翻译：描述了包括电极装置（30）的装置和方法，所述电极装置被构造为当所述装置处于非约束状态时呈现线圈构造，所述电极装置被成形为限定内腔（40）。至少一个电极（21）设置在电极装置上。至少一根电线（32）与电极连接。柔性引线（34）限定穿过其中的内腔（42），电线被容纳在引线内。探针（36）通过插入到由电极装置限定的内腔中将电极装置约束成直线构型。探针通过插入到由柔性引线限定的内腔中来另外加强柔性引线。还描述了其它应用。

2. 发明申请

US20170065824A1 ANNULAR ANTENNA 审中-公开
标题翻译： ANNULAR天线
公开(公告)号：US20170065824A1
公开(公告)日：2017-03-09
申请号：US15354313
申请日：2016-11-17
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Moshe Elazar , Nitai Hanani , Gal Ariav , Oded Meiri , Igor Gindin , Nir Armony , Yossi Gross , Offer Glasberg , Vadim Bernshtein
IPC分类号： A61N1/40 , A61B5/08 , A61F2/915 , A61B5/0402 , A61B5/0215
摘要： Apparatus and methods are described for use with a blood vessel of a subject. An annular antenna is placed inside the blood vessel such that radial expansion of the antenna is limited by a circumference of the blood vessel. A transmitter generates an inductive current in the antenna, by transmitting RF energy toward the antenna. A control unit measures the inductive current in the antenna, and, in response thereto, determines a physiological parameter of the subject. Other applications are also described.
摘要翻译：描述了与受试者的血管一起使用的装置和方法。将环形天线放置在血管内，使得天线的径向膨胀受到血管周长的限制。发射机通过向天线发射RF能量，在天线中产生感应电流。控制单元测量天线中的感应电流，并且响应于此，确定对象的生理参数。还描述了其它应用。

3. 发明授权

US11432949B2 Antenna posts 有权
公开(公告)号：US11432949B2
公开(公告)日：2022-09-06
申请号：US16864762
申请日：2020-05-01
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Yoav Katz , Fabian Lipperman , Tanhum Feld , Nadav Peleg , Gal Ariav
IPC分类号： A61F2/82 , A61N1/05 , A61N1/36 , A61N1/372 , A61N1/375 , A61N1/39 , A61F2/915 , A61F2/88 , A61F2/844
摘要： Apparatus and methods are described, including a stent configured to be placed in a lumen. The stent includes a generally cylindrical stent body including a plurality of struts, at least one electrode post protruding from the stent body, and a plurality of antenna posts protruding longitudinally from an end of the stent body. The antenna posts are longitudinally separated from the electrode post. An antenna is disposed annularly on the antenna posts, such that the antenna posts separate the antenna from the end of the stent body, and at least one electrode is coupled to the stent by being placed on the electrode post. Additional embodiments are also described.

4. 发明授权

US10828181B2 Annular antenna 有权
公开(公告)号：US10828181B2
公开(公告)日：2020-11-10
申请号：US15354313
申请日：2016-11-17
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Nitai Hanani , Gal Ariav , Igor Gindin , Yossi Gross
IPC分类号： A61F2/82 , A61F2/915 , A61N1/375 , A61N1/05 , A61N1/36 , A61F2/848 , A61B5/04 , A61B5/0215 , A61B5/0402 , A61B5/08 , A61N1/40
摘要： Apparatus and methods are described for use with a blood vessel of a subject. An annular antenna is placed inside the blood vessel such that radial expansion of the antenna is limited by a circumference of the blood vessel. A transmitter generates an inductive current in the antenna, by transmitting RF energy toward the antenna. A control unit measures the inductive current in the antenna, and, in response thereto, determines a physiological parameter of the subject. Other applications are also described.

5. 发明申请

US20160278951A1 POSTS WITH COMPLIANT JUNCTIONS 审中-公开
标题翻译：具有合适结点的位置
公开(公告)号：US20160278951A1
公开(公告)日：2016-09-29
申请号：US15034803
申请日：2014-11-06
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Yoav Katz , Fabian Lipperman , Alon Herman , Tanhum Feld , Nadav Peleg , Gal Ariav
IPC分类号： A61F2/844 , A61F2/915 , A61N1/372 , A61N1/375 , A61N1/05 , A61N1/36
摘要： Apparatus and methods are described, including a stent configured to be placed in a lumen. The stent includes a generally cylindrical stent body comprising a plurality of struts, and a plurality of antenna posts protruding longitudinally from an end of the stent body. Each of the antenna posts includes a proximal and distal portions, each of which is configured to be generally straight in the absence of any force being applied to the antenna post, and a compliant junction disposed between the proximal and distal portions, the proximal and distal portions being configured to flex with respect to one another about the compliant junction. An antenna is disposed annularly on the distal portions of the antenna posts, such that the antenna posts separate the antenna from the end of the stent body. Other applications are also described.
摘要翻译：描述了装置和方法，包括配置成放置在内腔中的支架。支架包括大体上圆柱形的支架主体，其包括多个支柱，以及从支架主体的端部纵向突出的多个天线柱。每个天线柱包括近端部分和远端部分，每个部分构造成在没有施加到天线柱的力的情况下大体上是直的，以及设置在近端部分和远端部分之间的柔顺连接部分部分被配置为围绕柔顺结合部彼此相对弯曲。天线环形地设置在天线柱的远端部分上，使得天线杆将天线与支架主体的端部分开。还描述了其它应用。

6. 发明授权

US10779965B2 Posts with compliant junctions 有权
公开(公告)号：US10779965B2
公开(公告)日：2020-09-22
申请号：US15034803
申请日：2014-11-06
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Yoav Katz , Fabian Lipperman , Tanhum Feld , Nadav Peleg , Gal Ariav
IPC分类号： A61F2/915 , A61F2/844 , A61N1/375 , A61N1/05 , A61N1/36 , A61N1/372 , A61N1/39 , A61F2/88 , A61F2/82
摘要： Apparatus and methods are described, including a stent configured to be placed in a lumen. The stent includes a generally cylindrical stent body comprising a plurality of struts, and a plurality of antenna posts protruding longitudinally from an end of the stent body. Each of the antenna posts includes a proximal and distal portions, each of which is configured to be generally straight in the absence of any force being applied to the antenna post, and a compliant junction disposed between the proximal and distal portions, the proximal and distal portions being configured to flex with respect to one another about the compliant junction. An antenna is disposed annularly on the distal portions of the antenna posts, such that the antenna posts separate the antenna from the end of the stent body. Other applications are also described.

7. 发明申请

US20200253754A1 ANTENNA POSTS 审中-公开
公开(公告)号：US20200253754A1
公开(公告)日：2020-08-13
申请号：US16864762
申请日：2020-05-01
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Yoav Katz , Fabian Lipperman , Tanhum Feld , Nadav Peleg , Gal Ariav
IPC分类号： A61F2/844 , A61F2/88 , A61N1/39 , A61N1/375 , A61N1/372 , A61N1/36 , A61N1/05 , A61F2/915
摘要： Apparatus and methods are described, including a stent configured to be placed in a lumen. The stent includes a generally cylindrical stent body including a plurality of struts, at least one electrode post protruding from the stent body, and a plurality of antenna posts protruding longitudinally from an end of the stent body. The antenna posts are longitudinally separated from the electrode post. An antenna is disposed annularly on the antenna posts, such that the antenna posts separate the antenna from the end of the stent body, and at least one electrode is coupled to the stent by being placed on the electrode post. Additional embodiments are also described.

8. 发明申请

US20140114377A1 VAGUS NERVE STIMULATION 审中-公开
标题翻译： VAGUS神经刺激
公开(公告)号：US20140114377A1
公开(公告)日：2014-04-24
申请号：US14144024
申请日：2013-12-30
申请人： Enopace Biomedical Ltd.
发明人： Amir Dagan , Yotam Reisner , Offer Glasberg , Nitai Hanani , Gal Ariav
IPC分类号： A61N1/36
CPC分类号： A61N1/36053 , A61N1/05 , A61N1/0556 , A61N1/36114 , A61N1/36564 , A61N1/3962
摘要： Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, acute myocardial infarction, and hypertension. In response to the identifying, an electrode is placed on a vagus nerve of the subject at a vagal site that is between the upper junction of the left thoracic vagal trunk with the left subclavian artery of the subject, and the thoracic vagal branching into an esophageal plexus of the subject. The subject is treated by electrically stimulating the vagal site by driving a current into the vagal site, via the electrode. Other applications are also described.
摘要翻译：描述了装置和方法，包括将受试者识别为患有选自充血性心力衰竭，舒张性心力衰竭，急性心肌梗死和高血压的病症。响应于识别，将电极放置在受试者的迷走神经上，该迷走神经位于左胸部迷走神经干线的上部交界处与受试者的左锁骨下动脉之间，以及分支到食道的胸部迷走神经主题丛。通过电极驱动电流进入迷走神经部位，通过电刺激迷走神经部位来治疗受试者。还描述了其它应用。

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