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1. 发明授权

US5514805A Assymetric synthesis process 失效
标题翻译：分析合成过程
公开(公告)号：US5514805A
公开(公告)日：1996-05-07
申请号：US225408
申请日：1994-04-08
申请人： Emil A. Broger , Werner Hofheinz , Arthur Meili
发明人： Emil A. Broger , Werner Hofheinz , Arthur Meili
IPC分类号： B01J31/24 , C07B53/00 , C07B61/00 , C07D213/30 , C07D401/06 , C07F9/50 , C07F15/00 , C07F17/02
CPC分类号： C07D401/06 , C07F15/008 , C07F17/02 , C07F9/5027
摘要： A novel process for the asymmetric hydrogenation of compounds of the formula: ##STR1## wherein R represent aryl or heteroaryl, to compounds of the formula: ##STR2## wherein R has the above significance, is carried out using rhodium-diphosphine complexes.
摘要翻译：对于下式化合物，其中R代表芳基或杂芳基的化合物，其中R具有上述含义，可以使用铑 - 二膦配合物进行下式化合物的不对称氢化的新方法：其中R代表芳基或杂芳基。

2. 发明授权

US08539980B2 Device for controlled operation of a surgical or dental drive unit 有权
标题翻译：用于外科或牙齿驱动单元的受控操作的装置
公开(公告)号：US08539980B2
公开(公告)日：2013-09-24
申请号：US13568596
申请日：2012-08-07
申请人： Peter Tanner , Arthur Meili
发明人： Peter Tanner , Arthur Meili
IPC分类号： E03B1/00 , F16K31/06
CPC分类号： A61C1/0038 , A61B2090/0801 , A61C1/0061 , Y10T137/88046
摘要： A device for operation of a surgical or dental drive unit includes a control valve attached to a drive unit to control a flow rate of a compressed fluid flowing from a compressed fluid source to the drive unit. The control valve includes (a) a first control arrangement controlling a rate of flow of the compressed fluid through the control valve; (b) a control switch; and (c) a control sleeve controlled by the control switch to axially move along a longitudinal axis of the drive unit between a first configuration in which the control valve is locked and closed to fluid flow and a second configuration in which the control valve is unlocked and the first control arrangement controls the rate of flow therethrough.
摘要翻译：用于手术或牙齿驱动单元的操作的装置包括附接到驱动单元的控制阀，以控制从压缩流体源流向驱动单元的压缩流体的流量。控制阀包括（a）控制压缩流体通过控制阀的流量的第一控制装置; （b）控制开关; 和（c）由所述控制开关控制的控制套筒，其在所述控制阀被锁定并关闭到流体流动的第一配置和所述控制阀被解锁的第二配置之间沿着所述驱动单元的纵向轴线轴向移动并且第一控制装置控制其中流动的速率。

3. 发明授权

US08256460B2 Device for controlled operation of a surgical or dental drive unit 有权
标题翻译：用于外科或牙齿驱动单元的受控操作的装置
公开(公告)号：US08256460B2
公开(公告)日：2012-09-04
申请号：US11915263
申请日：2005-05-25
申请人： Peter Tanner , Arthur Meili
发明人： Peter Tanner , Arthur Meili
IPC分类号： F16K35/00
CPC分类号： A61C1/0038 , A61B2090/0801 , A61C1/0061 , Y10T137/88046
摘要： A device for controlled operation of a surgical or dental drive unit driven by a compressed fluid source p available in the operating room and comprising A) a control valve attachable to the drive unit for controlling a flow rate of a compressed fluid flowing from a compressed fluid source p to a drive unit; B) a first control means by means of which the control valve is operable; and C) a second control means by means of which a flow rate of compressed fluid may be controlled. The device further comprises D) a control switch which is attached to the control valve and allowing to select between at least three positions (A;B;C): in position A the control valve is locked and closed; in position B the control valve is unlocked and a flow rate of the compressed fluid is controllable by means of the first control means; and in position C the control valve is unlocked and open permitting the control of a flow rate by means of the second control means.
摘要翻译：一种用于由手术室中可用的压缩流体源p驱动的外科或牙齿驱动单元的受控操作的装置，包括：A）附接到驱动单元的控制阀，用于控制从压缩流体流出的压缩流体的流量来源p到驱动单元; B）控制阀可操作的第一控制装置; 和C）可以控制压缩流体的流量的第二控制装置。该装置还包括D）控制开关，其连接到控制阀并允许在至少三个位置（A; B; C）之间进行选择：在位置A，控制阀被锁定和关闭; 在位置B中，控制阀被解锁，并且通过第一控制装置控制压缩流体的流量; 并且在位置C中，控制阀被解锁和打开，允许通过第二控制装置控制流量。

4. 发明授权

US09365494B2 Process for synthesis of amino-methyl tetralin derivatives 有权
标题翻译：合成氨基 - 甲基四氢化萘衍生物的方法
公开(公告)号：US09365494B2
公开(公告)日：2016-06-14
申请号：US13359329
申请日：2012-01-26
申请人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
发明人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
IPC分类号： C07C231/18 , B01J31/24 , C07C315/02 , C07C319/14 , C07C319/20 , B01J31/18
CPC分类号： C07C231/18 , B01J31/1805 , B01J31/24 , B01J31/2409 , B01J2231/645 , B01J2531/821 , C07B2200/07 , C07C315/02 , C07C319/14 , C07C319/20 , C07C2602/10 , C07C237/24 , C07C317/32 , C07C323/22 , C07C323/62 , C07C323/38 , C07C323/44
摘要： Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2 Ru(Z)2(L) j1; Ru(E)(E′)(L)(D) j2; wherein m, n, Ar, Y, R1E, E′, D, Z and L are as defined herein.
摘要翻译：在式j1或j2 Ru（Z）2（L）j1的钌催化剂存在下，用氢气还原式I的二氢萘酰胺化合物，制备式k1或k2化合物的方法; Ru（E）（E'）（L）（D）j2; 其中m，n，Ar，Y，R1E，E'，D，Z和L如本文所定义。

5. 发明申请

US20120329007A1 Device for Controlled Operation of a Surgical or Dental Drive Unit 有权
标题翻译：手术或牙科驱动装置的受控操作装置
公开(公告)号：US20120329007A1
公开(公告)日：2012-12-27
申请号：US13568596
申请日：2012-08-07
申请人： Peter Tanner , Arthur Meili
发明人： Peter Tanner , Arthur Meili
IPC分类号： A61C19/00 , A61C3/00 , A61B17/00
CPC分类号： A61C1/0038 , A61B2090/0801 , A61C1/0061 , Y10T137/88046
摘要： A device for operation of a surgical or dental drive unit includes a control valve attached to a drive unit to control a flow rate of a compressed fluid flowing from a compressed fluid source to the drive unit. The control valve includes (a) a first control arrangement controlling a rate of flow of the compressed fluid through the control valve; (b) a control switch; and (c) a control sleeve controlled by the control switch to axially move along a longitudinal axis of the drive unit between a first configuration in which the control valve is locked and closed to fluid flow and a second configuration in which the control valve is unlocked and the first control arrangement controls the rate of flow therethrough.
摘要翻译：用于外科或牙科驱动单元的操作的装置包括附接到驱动单元的控制阀，以控制从压缩流体源流向驱动单元的压缩流体的流量。控制阀包括（a）控制压缩流体通过控制阀的流量的第一控制装置; （b）控制开关; 和（c）由所述控制开关控制的控制套筒，其在所述控制阀被锁定并关闭到流体流动的第一配置和所述控制阀被解锁的第二配置之间沿着所述驱动单元的纵向轴线轴向移动并且第一控制装置控制其中流动的速率。

6. 发明授权

US08119842B2 Process for synthesis of amino-methyl tetralin derivatives 有权
标题翻译：合成氨基 - 甲基四氢化萘衍生物的方法
公开(公告)号：US08119842B2
公开(公告)日：2012-02-21
申请号：US12637548
申请日：2009-12-14
申请人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
发明人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
IPC分类号： C07C231/18 , C07C231/12 , C07C209/50
CPC分类号： C07C231/18 , B01J31/1805 , B01J31/24 , B01J31/2409 , B01J2231/645 , B01J2531/821 , C07B2200/07 , C07C315/02 , C07C319/14 , C07C319/20 , C07C2602/10 , C07C237/24 , C07C317/32 , C07C323/22 , C07C323/62 , C07C323/38 , C07C323/44
摘要： Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2 Ru(Z)2(L) j1; Ru(E)(E′)(L)(D) j2; wherein m, n, Ar, Y, R1 E, E′, D, Z and L are as defined herein.
摘要翻译：在式j1或j2 Ru（Z）2（L）j1的钌催化剂存在下，用氢气还原式I的二氢萘酰胺化合物，制备式k1或k2化合物的方法; Ru（E）（E'）（L）（D）j2; 其中m，n，Ar，Y，R E，E'，D，Z和L如本文所定义。

7. 发明申请

US20100160682A1 PROCESS FOR SYNTHESIS OF AMINO-METHYL TETRALIN DERIVATIVES 有权
标题翻译：氨基甲基四环素衍生物的合成方法
公开(公告)号：US20100160682A1
公开(公告)日：2010-06-24
申请号：US12637548
申请日：2009-12-14
申请人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
发明人： Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
IPC分类号： C07C273/02 , C07C231/02
CPC分类号： C07C231/18 , B01J31/1805 , B01J31/24 , B01J31/2409 , B01J2231/645 , B01J2531/821 , C07B2200/07 , C07C315/02 , C07C319/14 , C07C319/20 , C07C2602/10 , C07C237/24 , C07C317/32 , C07C323/22 , C07C323/62 , C07C323/38 , C07C323/44
摘要： Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2 Ru(Z)2(L) j1; Ru(E)(E′)(L)(D) j2; wherein m, n, Ar, Y, R1 E, E′, D, Z and L are as defined herein.
摘要翻译：在式j1或j2 Ru（Z）2（L）j1的钌催化剂存在下，用氢气还原式I的二氢萘酰胺化合物，制备式k1或k2化合物的方法; Ru（E）（E'）（L）（D）j2; 其中m，n，Ar，Y，R E，E'，D，Z和L如本文所定义。

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