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1. 发明申请

US20060079687A1 Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) 有权
标题翻译：可用作β-分泌酶（BACE）抑制剂的新型2-氨基 - 喹唑啉衍生物
公开(公告)号：US20060079687A1
公开(公告)日：2006-04-13
申请号：US11197669
申请日：2005-08-04
申请人： Ellen Baxter , Francois Bischoff , Robert Boyd , Mirielle Braeken , Steve Coats , Yifang Huang , Alfonzo Jordan , Chi Luo , Marc Mercken , Serge Maria Pieters , Allen Reitz , Charles Reynolds , Tina Ross , Brett Tounge , Mark Schulz , Hans De Winter
发明人： Ellen Baxter , Francois Bischoff , Robert Boyd , Mirielle Braeken , Steve Coats , Yifang Huang , Alfonzo Jordan , Chi Luo , Marc Mercken , Serge Maria Pieters , Allen Reitz , Charles Reynolds , Tina Ross , Brett Tounge , Mark Schulz , Hans De Winter
IPC分类号： C07D239/84 , C07D403/02
CPC分类号： C07D413/06 , C07D239/84 , C07D401/06 , C07D403/06 , C07D403/12 , C07D405/06
摘要： The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.
摘要翻译：本发明涉及新的2-氨基-3,4-二氢 - 喹唑啉衍生物，含有它们的药物组合物及其在治疗阿尔茨海默病（AD）和相关病症中的用途。本发明的化合物是β-分泌酶的抑制剂，也称为β-位点切割酶和BACE。

2. 发明申请

US20070259898A1 NOVEL 2-AMINO-3,4-DIHYDRO-PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE) 有权
标题翻译：新型2-氨基-3,4-二氢吡啶并[3,4-D]吡啶衍生物作为β-分泌酶（BACE）的抑制剂有用
公开(公告)号：US20070259898A1
公开(公告)日：2007-11-08
申请号：US11552792
申请日：2006-10-25
申请人： Ellen Baxter , Christopher Creighton , Yifang Huang , Chi Luo , Michael Parker , Allen Reitz , Charles Reynolds , Tina Ross , Eric Strobel , Brett Tounge
发明人： Ellen Baxter , Christopher Creighton , Yifang Huang , Chi Luo , Michael Parker , Allen Reitz , Charles Reynolds , Tina Ross , Eric Strobel , Brett Tounge
IPC分类号： A61K31/519 , A61P25/28 , C07D211/72 , C07D471/04
CPC分类号： C07D213/73 , C07D471/04
摘要： The present invention is directed to novel 2-amino-3,4-dihydro-pyrido[3,4-d]pyrimidine derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
摘要翻译：本发明涉及新的2-氨基-3,4-二氢 - 吡啶并[3,4-d]嘧啶衍生物，含有它们的药物组合物及其在治疗阿尔茨海默病（AD）和相关疾病中的用途。本发明的化合物是β-分泌酶的抑制剂，也称为β-位点切割酶和BACE，BACE1，Asp2和memapsin2。

3. 发明申请

US20060079686A1 Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) 有权
公开(公告)号：US20060079686A1
公开(公告)日：2006-04-13
申请号：US11197608
申请日：2005-08-04
申请人： Ellen Baxter , Robert Boyd , Steven Coats , Alfonzo Jordan , Allen Reitz , Charles Reynolds , Malcolm Scott
发明人： Ellen Baxter , Robert Boyd , Steven Coats , Alfonzo Jordan , Allen Reitz , Charles Reynolds , Malcolm Scott
IPC分类号： C07D403/02 , C07D239/84
CPC分类号： C07D215/227 , C07D401/06 , C07D403/06 , C07D403/12 , C07D405/06 , C07D413/06
摘要： The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.

4. 发明申请

US20070232630A1 MACROCYCLE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE) 有权
标题翻译：大分子衍生物作为β-分泌酶（BACE）的抑制剂有用
公开(公告)号：US20070232630A1
公开(公告)日：2007-10-04
申请号：US11671732
申请日：2007-02-06
申请人： Ellen Baxter , Allen Reitz , Michael Parker , Yifang Huang , Chih Ho , Eric Strobel , Charles Reynolds
发明人： Ellen Baxter , Allen Reitz , Michael Parker , Yifang Huang , Chih Ho , Eric Strobel , Charles Reynolds
IPC分类号： A61K31/519 , C07D491/14 , C07D487/14
CPC分类号： C07D498/08 , C07D487/08
摘要： The present invention is directed to macrocycle derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
摘要翻译：本发明涉及大环衍生物，含有它们的药物组合物及其在治疗阿尔茨海默病（AD）和相关疾病中的用途。本发明的化合物是β-分泌酶的抑制剂，也称为β-位点切割酶和BACE，BACE1，Asp2和memapsin2。

5. 发明申请

US20070240575A1 CORONA GROUND ELEMENT 有权
标题翻译： CORONA地面元素
公开(公告)号：US20070240575A1
公开(公告)日：2007-10-18
申请号：US11405723
申请日：2006-04-18
申请人： Bruce Kiern , Dennis Lamb , Charles Reynolds , Christopher Paterson
发明人： Bruce Kiern , Dennis Lamb , Charles Reynolds , Christopher Paterson
IPC分类号： B03C3/41
CPC分类号： B03C3/08 , B03C3/32 , B03C3/41 , B03C3/86 , B03C2201/04
摘要： A corona ground element for use in a pre-ionizer of an electrostatic precipitator is provided according to an embodiment of the invention. The corona ground element includes a substantially elongate body including a proximate end and a distal end and first and second projections formed on the proximate end and the distal end. The first and second projections are adapted to retain the corona plate in the electrostatic precipitator.
摘要翻译：根据本发明的实施例提供了一种用于静电除尘器预电离器的电晕接地元件。电晕接地元件包括基本上细长的主体，其包括近端和远端以及形成在近端和远端上的第一和第二突起。第一和第二突起适于将电晕板保持在静电除尘器中。

6. 发明申请

US20070240573A1 RETAINER FOR USE WITH A CORONA GROUND ELEMENT OF AN ELECTROSTATIC PRECIPITATOR 失效
标题翻译：保持器与静电放电器的CORONA接地元件一起使用
公开(公告)号：US20070240573A1
公开(公告)日：2007-10-18
申请号：US11405751
申请日：2006-04-18
申请人： Bruce Kiern , Dennis Lamb , Charles Reynolds , Christopher Paterson
发明人： Bruce Kiern , Dennis Lamb , Charles Reynolds , Christopher Paterson
IPC分类号： B03C3/41
CPC分类号： B03C3/86
摘要： A retainer for use with a corona ground element of an electrostatic precipitator is provided according to an embodiment of the invention. The retainer includes a body and a retainer aperture extending at least partially through the body and adapted to receive a projection extending from the corona ground element. The retainer aperture is configured to receive the projection as a press fit.
摘要翻译：根据本发明的实施例提供了一种用于静电除尘器的电晕接地元件的保持器。保持器包括主体和保持器孔，其至少部分延伸穿过主体并且适于接收从电晕接地元件延伸的突起。保持器孔被构造成接受压配合的突起。

7. 发明申请

US20070183910A1 Motor mount assembly for an air cleaner 有权
标题翻译：用于空气净化器的电机安装组件
公开(公告)号：US20070183910A1
公开(公告)日：2007-08-09
申请号：US11350713
申请日：2006-02-09
申请人： Charles Reynolds , Owen Bourgeois , Christopher Paterson
发明人： Charles Reynolds , Owen Bourgeois , Christopher Paterson
IPC分类号： F04B17/00
CPC分类号： F04D29/626 , F04D29/544
摘要： A motor mount assembly for an air cleaner is provided according to an embodiment of the invention. The motor mount assembly includes a motor ring adapted for receiving a motor, a mount ring adapted to be received in the air cleaner, and a plurality of mounting vanes extending between the motor ring and the mount ring. A mounting vane of the plurality of mounting vanes includes a proximal end and a distal end. The distal end is affixed to the motor ring and the proximal end is affixed to the mount ring.
摘要翻译：根据本发明的实施例，提供了一种用于空气净化器的电动机安装组件。电动机安装组件包括适于接收电动机的电动机环，适于容纳在空气滤清器中的安装环以及在电动机环和安装环之间延伸的多个安装叶片。多个安装叶片的安装叶片包括近端和远端。远端固定在马达环上，近端固定在安装环上。

8. 发明申请

US20070180801A1 Air cleaner airflow shaper 有权
标题翻译：空气净化器气流成形机
公开(公告)号：US20070180801A1
公开(公告)日：2007-08-09
申请号：US11351189
申请日：2006-02-09
申请人： Christopher Paterson , Charles Reynolds , Paul Moshenrose
发明人： Christopher Paterson , Charles Reynolds , Paul Moshenrose
IPC分类号： B01D46/00
CPC分类号： F24F3/166 , F24F2001/0096 , F24F2003/1682
摘要： An airflow shaper for use in an air cleaner is provided according to an embodiment of the invention. The airflow shaper includes a body including a substantially central axis and a raised central region formed on the body. The raised central region transitions an impinging axial airflow into a substantially radial airflow or transitions an impinging radial airflow into a substantially axial airflow.
摘要翻译：根据本发明的实施例提供了一种用于空气滤清器的气流成形器。气流整形器包括主体，其包括基本上中心的轴线和形成在主体上的凸起的中心区域。凸起的中心区域将冲击的轴向气流转变成基本上径向的气流，或者将冲击的径向气流转变成基本上轴向的气流。

9. 发明申请

US20070180996A1 Tower air cleaner with improved airflow 审中-公开
标题翻译：塔式空气净化器具有改善气流
公开(公告)号：US20070180996A1
公开(公告)日：2007-08-09
申请号：US11351005
申请日：2006-02-09
申请人： Christopher Paterson , Charles Reynolds , Owen Bourgeois , Paul Moshenrose
发明人： Christopher Paterson , Charles Reynolds , Owen Bourgeois , Paul Moshenrose
IPC分类号： B03C3/36
CPC分类号： B03C3/32 , B03C3/365 , F24F2003/1635 , F24F2003/1682 , Y02A50/21
摘要： A tower air cleaner is provided according to an embodiment of the invention. The tower air cleaner includes a base portion, a tower portion extending substantially vertically above the base portion, an air inlet extending substantially around a circumference of the tower portion, wherein an inlet airflow is admitted around substantially 360 degrees of the circumference, and an air outlet in communication with the air inlet.
摘要翻译：根据本发明的实施例提供塔式空气滤清器。塔式空气净化器包括基座部分，基部垂直地延伸的塔架部分，基本上围绕塔架部分的圆周延伸的空气入口，其中入口气流围绕圆周的大约360度进入，并且空气出口与进气口连通。

10. 发明申请

US20060162564A1 Air cleaner with improved airflow 失效
标题翻译：空气净化器具有改善的气流
公开(公告)号：US20060162564A1
公开(公告)日：2006-07-27
申请号：US11042746
申请日：2005-01-25
申请人： Christopher Paterson , Charles Reynolds , Owen Bourgeois
发明人： Christopher Paterson , Charles Reynolds , Owen Bourgeois
IPC分类号： B03C3/14
CPC分类号： B03C3/011 , B03C3/155 , B03C3/32 , Y02A50/2357
摘要： An air cleaner is provided according to an embodiment of the invention. The air cleaner includes an air duct including an inlet end and an outlet end, a pre-filter positioned at the inlet end, an electrostatic precipitator positioned in the air duct downstream of the pre-filter, a post-filter positioned in the air duct downstream of the electrostatic precipitator, and a fan unit positioned in the air duct downstream of the post-filter. Airflow travels from the inlet end to the outlet end. The airflow first encounters the pre-filter, encounters the electrostatic precipitator after encountering the pre-filter, encounters the post-filter after encountering the electrostatic precipitator, and encounters the fan unit after encountering the post-filter. Each of the pre-filter, the electrostatic precipitator, and the post-filter can be separately installed and removed from the air duct.
摘要翻译：根据本发明的实施例提供了一种空气净化器。空气净化器包括一个包括入口端和出口端的空气管道，位于入口端的预过滤器，位于预过滤器下游的空气管道中的静电除尘器，位于空气管道中的后置过滤器在静电除尘器的下游，以及位于后过滤器下游的空气管道中的风扇单元。气流从入口端行进到出口端。气流首先遇到预过滤器，遇到预过滤器后遇到静电除尘器，遇到静电除尘器后遇到后置过滤器，遇到后置过滤器后遇到风扇单元。预过滤器，静电除尘器和后置过滤器中的每一个可以分开安装并从空气管道中移除。

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