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1. 发明授权

US07755010B2 Non-invasive microwave analysis methods 失效
标题翻译：无创微波分析方法
公开(公告)号：US07755010B2
公开(公告)日：2010-07-13
申请号：US11589625
申请日：2006-10-30
申请人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
发明人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
IPC分类号： H05B6/64 , A61B5/05
CPC分类号： G01N22/00 , A61B5/05 , A61B5/0507 , A61B2562/02 , A61B2562/046
摘要： A non-invasive microwave analysis method determines scattered phase and/or amplitude data for a liquid in a container. A transmitter antenna transmits microwaves that scatter from the container and the liquid in the container. One or more receiver antennas convert the microwaves into microwave electronic signals that are processed to determine the scattered phase and/or amplitude data. Another non-invasive microwave screening method includes placing a container of an unknown liquid in a tank. The container is separated by a membrane from coupling liquid in the tank. Microwave radiation transmits from a transmitter antenna and scatters from the container and the unknown liquid. One or more receiver antennas convert the microwave radiation into microwave electronic signals. The microwave electronic signals are processed to determine scattered phase and/or amplitude data. A pass result or a fail result is determined based on the scattered phase and/or amplitude data.
摘要翻译：非侵入性微波分析方法确定容器中的液体的散射相位和/或振幅数据。发射机天线发射从容器散射的微波和容器中的液体。一个或多个接收器天线将微波转换成微波电子信号，其被处理以确定散射相位和/或振幅数据。另一种非侵入性微波筛选方法包括将未知液体的容器放置在罐中。容器通过膜与罐中的耦合液分离。微波辐射从发射天线发射并从容器和未知液体散射。一个或多个接收机天线将微波辐射转换为微波电子信号。处理微波电子信号以确定散射相位和/或振幅数据。基于散射相位和/或振幅数据确定通过结果或失败结果。

2. 发明授权

US07319212B2 Non-invasive microwave analysis systems 失效
标题翻译：无创微波分析系统
公开(公告)号：US07319212B2
公开(公告)日：2008-01-15
申请号：US11589434
申请日：2006-10-30
申请人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
发明人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
IPC分类号： H05B6/64 , A61B5/05
CPC分类号： G01N22/00 , A61B5/05 , A61B5/0507 , A61B2562/02 , A61B2562/046
摘要： A non-invasive microwave analysis system determines scattered phase and/or amplitude data for a liquid in a container. A tank holds coupling liquid; the system includes a membrane for separating the liquid container from the coupling liquid. A transmitter antenna situated within the coupling liquid transmits microwaves. One or more receiver antennas within the coupling liquid convert microwave radiation that scatters from the liquid in the container into microwave electronic signals. Electronics process the microwave electronic signals to determine scattered phase and/or amplitude values of the microwave radiation.
摘要翻译：非侵入式微波分析系统确定容器中的液体的散射相位和/或振幅数据。储罐保持耦合液体; 该系统包括用于将液体容器与耦合液分离的膜。位于耦合液体内的发射器天线透射微波。耦合液体内的一个或多个接收器天线将从容器中的液体散射的微波辐射转换为微波电子信号。电子处理微波电子信号以确定微波辐射的散射相位和/或振幅值。

3. 发明授权

US07164105B2 Non-invasive microwave analysis systems 失效
标题翻译：无创微波分析系统
公开(公告)号：US07164105B2
公开(公告)日：2007-01-16
申请号：US11080726
申请日：2005-03-15
申请人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
发明人： Edward M Godshalk , Timothy Raynolds , Paul M. Meaney , Keith D. Paulsen , Greg Burke
IPC分类号： H05B6/64 , A61B5/05
CPC分类号： G01N22/00 , A61B5/05 , A61B5/0507 , A61B2562/02 , A61B2562/046
摘要： Non-invasive microwave analysis systems and methods determine scattered phase data for a liquid in a container. A transmitter antenna situated within coupling liquid separated from the container by a flexible membrane transmits microwaves that scatter from the container and the liquid in the container. One or more receiver antennas within the coupling liquid convert the microwaves into microwave electronic signals that are processed to determine the scattered phase data.Non-invasive microwave analysis systems and methods image a portion of a biological subject. A transmitter antenna situated within coupling liquid separated from the subject by a flexible membrane transmits microwaves that scatter from the container and the subject. One or more receiver antennas within the coupling liquid convert the microwaves into microwave electronic signals that are processed to reconstruct a cross-sectional image of the subject.
摘要翻译：非侵入性微波分析系统和方法确定容器中液体的散射相数据。位于通过柔性膜从容器分离的耦合液体内的发射器天线透射从容器和容器中的液体散射的微波。耦合液体内的一个或多个接收器天线将微波转换成微波电子信号，其被处理以确定散射相位数据。非侵入式微波分析系统和方法对生物学科的一部分进行成像。位于通过柔性膜与被摄体分离的耦合液体内的发射器天线透射从容器和被摄体散射的微波。耦合液体内的一个或多个接收器天线将微波转换成微波电子信号，其被处理以重建对象的横截面图像。

4. 发明申请

US20090036766A1 Imaging By Magnetic Resonance Adsorption, Elastography And Tomography 有权
标题翻译：通过磁共振吸附，弹性成像和层析成像
公开(公告)号：US20090036766A1
公开(公告)日：2009-02-05
申请号：US12246259
申请日：2008-10-06
申请人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
发明人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
IPC分类号： A61B5/055
CPC分类号： G01R33/56358 , A61B5/0035 , A61B5/05 , A61B5/0507 , G01R33/56316
摘要： A microwave imaging system provides superior breast imaging resolution by combining MR microwave absorption and MR-compatible microwave tomography calculations. These techniques may also be supplemented with magnetic resonance elastography techniques, for example, to facilitate quick multispectral imaging.
摘要翻译：微波成像系统通过组合MR微波吸收和MR兼容的微波层析成像计算来提供优异的乳房成像分辨率。这些技术还可以用磁共振弹性成像技术进行补充，例如，以促进快速多光谱成像。

5. 发明授权

US06448788B1 Fixed array microwave imaging apparatus and method 有权
标题翻译：固定阵列微波成像装置及方法
公开(公告)号：US06448788B1
公开(公告)日：2002-09-10
申请号：US09580309
申请日：2000-05-26
申请人： Paul M. Meaney , Keith D. Paulsen , Margaret W. Fanning
发明人： Paul M. Meaney , Keith D. Paulsen , Margaret W. Fanning
IPC分类号： G01R2732
CPC分类号： A61B5/0507 , A61B5/0536 , H01Q21/20 , H01Q21/28
摘要： An improved method and apparatus for microwave imaging of an inhomogeneous target, in particular of biological tissue, compensates for the interactions between active antennae and nonactive antennae. Measured electric field data are processed in magnitude and phase form so that unwrapped phase information may be used directly in the image reconstruction. Initial finite element measurements and calculations are used to determine the perimeter dimensions of the target being examined, resulting in more accurate image reconstructions. An improved regularization technique is a hybrid of a Marquardt regularization scheme with a spatial filtering technique and a Tikhonov regularization scheme. An improved switching matrix enables simultaneous sampling of electric field data from a plurality of receiving antennae.
摘要翻译：用于微波成像不均匀靶（特别是生物组织）的改进方法和装置补偿了有源天线与非主动天线之间的相互作用。测量的电场数据以幅度和相位形式被处理，使得可以在图像重建中直接使用解包相位信息。初始有限元测量和计算用于确定正在检查的目标的周长尺寸，导致更准确的图像重建。改进的正则化技术是Marquardt正则化方案与空间滤波技术和Tikhonov正则化方案的混合。改进的开关矩阵能够从多个接收天线同时采样电场数据。

6. 发明授权

US07439736B2 Imaging by magnetic resonance adsorption, elastography and tomography 有权
标题翻译：通过磁共振吸附，弹性成像和断层扫描成像
公开(公告)号：US07439736B2
公开(公告)日：2008-10-21
申请号：US10529451
申请日：2003-09-26
申请人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
发明人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
IPC分类号： G01V3/00
CPC分类号： G01R33/56358 , A61B5/0035 , A61B5/05 , A61B5/0507 , G01R33/56316
摘要： Magnetic resonance elastography pulse sequences for encoding position and motion of spins, and methods of using the pulse sequences are disclosed. The pulse sequences utilize imaging gradients, comprising a positive lobe and a negative lobe having non-symmetric amplitudes, to encode harmonic or wave motion within a specimen, such as tissue.
摘要翻译：公开了用于编码自旋的位置和运动的磁共振弹性成像脉冲序列，以及使用脉冲序列的方法。脉冲序列利用成像梯度，包括具有非对称幅度的正叶片和负叶片，以在样本（例如组织）内编码谐波或波动。

7. 发明授权

US08207733B2 Imaging by magnetic resonance adsorption, elastography and tomography 有权
标题翻译：通过磁共振吸附，弹性成像和断层扫描成像
公开(公告)号：US08207733B2
公开(公告)日：2012-06-26
申请号：US12246259
申请日：2008-10-06
申请人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
发明人： Paul M. Meaney , Keith D. Paulsen , John B. Weaver
IPC分类号： G01V3/00
CPC分类号： G01R33/56358 , A61B5/0035 , A61B5/05 , A61B5/0507 , G01R33/56316
摘要： A microwave imaging system provides superior breast imaging resolution by combining MR microwave absorption and MR-compatible microwave tomography calculations. These techniques may also be supplemented with magnetic resonance elastography techniques, for example, to facilitate quick multispectral imaging.
摘要翻译：微波成像系统通过组合MR微波吸收和MR兼容的微波层析成像计算来提供优异的乳房成像分辨率。这些技术还可以用磁共振弹性成像技术进行补充，例如，以促进快速多光谱成像。

8. 发明授权

US08977340B2 System and method for collection and use of magnetic resonance data and microwave data to identify boundaries of interest 有权
标题翻译：用于收集和使用磁共振数据和微波数据以识别感兴趣边界的系统和方法
公开(公告)号：US08977340B2
公开(公告)日：2015-03-10
申请号：US13577788
申请日：2011-02-09
申请人： Amir H. Golnabi , Keith D. Paulsen , Paul M. Meaney
发明人： Amir H. Golnabi , Keith D. Paulsen , Paul M. Meaney
IPC分类号： A61B5/055 , A61B5/00 , A61B6/03 , G06T7/00 , A61B5/05
CPC分类号： A61B5/0035 , A61B5/0059 , A61B5/0507 , A61B5/055 , A61B5/4312 , A61B6/032 , G06T7/0012 , G06T2207/10081 , G06T2207/10088 , G06T2207/30068
摘要： A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction.
摘要翻译：提出了一种用于在材料的高分辨率空间图像内检测介电常数和电导率边界的系统和方法。材料的电学性质，例如介电常数和电导率可有助于识别材料的物理性质。可以在诸如MR图像的空间图像中识别组织内的结构边界。图像重建算法可以将这些结构边界与组织的微波图像结合，以确定结构边界内的介电常数和电导率参数。在软组织的情况下，微波图像可以与空间图像同时捕获。可以在与刚性组织的空间图像不同的时间拍摄微波图像。该方法可以用于二维或三维图像重建。

9. 发明申请

US20140375337A1 Planar Probe And System For Measuring Dielectric Properties Of Biological Materials 有权
标题翻译：用于测量生物材料介电性能的平面探头和系统
公开(公告)号：US20140375337A1
公开(公告)日：2014-12-25
申请号：US14117368
申请日：2012-05-11
申请人： Paul M. Meaney , Tina Zhou , Andrea Borsic , Alexander T. Farkas , Keith D. Paulsen
发明人： Paul M. Meaney , Tina Zhou , Andrea Borsic , Alexander T. Farkas , Keith D. Paulsen
IPC分类号： G01N27/02 , G01N33/483 , G01N33/49
CPC分类号： G01N27/02 , G01N27/221 , G01N33/4833 , G01N33/49 , G01N2333/435
摘要： A probe sensor has a printed circuit comprising a coplanar transmission line, a ground plane, a plated-through contact via, and a part-circular ring of ground vias surrounding the contact via. The coplanar transmission line and ground plane are formed on a first layer of the printed circuit, and the contact via and part-circular ring of ground vias are plated with a conductive biocompatible material on a second layer of the printed circuit. A system uses a network analyzer with the probe to measure electrical properties of biological tissue. Also described is a method of using the system to determine qualities of stored blood.
摘要翻译：探头传感器具有印刷电路，该印刷电路包括共面传输线，接地平面，电镀通孔接触通孔和围绕接触通孔的接地通孔的部分圆形环。共面传输线和接地平面形成在印刷电路的第一层上，并且接地通路的接触通孔和部分圆形环在印刷电路的第二层上镀有导电生物相容性材料。系统使用带有探针的网络分析仪来测量生物组织的电学性质。还描述了使用该系统来确定储存血液的质量的方法。

10. 发明申请

US20130204118A1 SYSTEM AND METHOD FOR COLLECTION & USE OF MAGNETIC RESONANCE DATA & MICROWAVE DATA TO IDENTIFY BOUNDARIES OF INTEREST 有权
标题翻译：用于收集和使用磁共振数据和微波数据识别边界的系统和方法
公开(公告)号：US20130204118A1
公开(公告)日：2013-08-08
申请号：US13577788
申请日：2011-02-09
申请人： Amir H. Golnabi , Keith D. Paulsen , Paul M. Meaney
发明人： Amir H. Golnabi , Keith D. Paulsen , Paul M. Meaney
IPC分类号： A61B5/00 , A61B6/03 , A61B5/055
CPC分类号： A61B5/0035 , A61B5/0059 , A61B5/0507 , A61B5/055 , A61B5/4312 , A61B6/032 , G06T7/0012 , G06T2207/10081 , G06T2207/10088 , G06T2207/30068
摘要： A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction.
摘要翻译：提出了一种用于在材料的高分辨率空间图像内检测介电常数和电导率边界的系统和方法。材料的电学性质，例如介电常数和电导率可有助于识别材料的物理性质。可以在诸如MR图像的空间图像中识别组织内的结构边界。图像重建算法可以将这些结构边界与组织的微波图像结合，以确定结构边界内的介电常数和电导率参数。在软组织的情况下，微波图像可以与空间图像同时捕获。可以在与刚性组织的空间图像不同的时间拍摄微波图像。该方法可以用于二维或三维图像重建。

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