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1. 发明授权

US08060171B2 Medical sensor for reducing motion artifacts and technique for using the same 有权
公开(公告)号：US08060171B2
公开(公告)日：2011-11-15
申请号：US11497089
申请日：2006-08-01
申请人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
发明人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
IPC分类号： A61B5/1455
CPC分类号： A61B5/6886 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B5/6844 , Y10T29/49826
摘要： A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector.

2. 发明授权

US08728059B2 System and method for assuring validity of monitoring parameter in combination with a therapeutic device 有权
标题翻译：监测参数与治疗装置结合的有效性的系统和方法
公开(公告)号：US08728059B2
公开(公告)日：2014-05-20
申请号：US11541302
申请日：2006-09-29
申请人： Edward Karst , Clark R. Baker, Jr.
发明人： Edward Karst , Clark R. Baker, Jr.
IPC分类号： A61K9/22
CPC分类号： A61B5/4821 , A61B5/024 , A61B5/0402 , A61B5/145 , A61B5/14532 , A61M5/1723 , A61M2005/14208 , A61M2230/201
摘要： The disclosed embodiments relate to a system and method for assuring validity of monitoring parameters in combination with a therapeutic device. An exemplary embodiment of the present technique comprises perturbing a treatment administered to a patient, measuring at least one parameter of the patient reflecting the underlying physiological state and associated with the treatment, and comparing the perturbations of the treatment to measurements of the at least one parameter to determine if the perturbations to the treatment are reflected by the parameter.
摘要翻译：所公开的实施例涉及用于与治疗装置结合来确保监测参数的有效性的系统和方法。本技术的示例性实施方案包括扰乱施用于患者的治疗，测量反映潜在生理状态并与治疗相关联的患者的至少一个参数，并将治疗的扰动与至少一个参数的测量值进行比较以确定治疗的扰动是否反映在参数中。

3. 发明授权

US08965473B2 Medical sensor for reducing motion artifacts and technique for using the same 有权
标题翻译：用于减少运动伪像的医疗传感器及其使用技术
公开(公告)号：US08965473B2
公开(公告)日：2015-02-24
申请号：US13267681
申请日：2011-10-06
申请人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
发明人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
IPC分类号： A61B5/1455 , A61B5/00
CPC分类号： A61B5/6886 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B5/6844 , Y10T29/49826
摘要： A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector.
摘要翻译：用于脉搏血氧饱和度测定的传感器或利用分光光度法的其它应用可适用于通过固定发射器和检测器之间的光学距离来减少运动伪影。柔性传感器设置有加强构件，以在应用于患者时将传感器的发射器和检测器保持在相对固定的位置。此外，环形或部分环形的传感器适于在施加到患者时将传感器的发射器和检测器保持在相对固定的位置。夹式传感器设置有间隔器，该间隔件控制发射器和检测器之间的距离。

4. 发明授权

US08175670B2 Pulse oximetry signal correction using near infrared absorption by water 有权
标题翻译：使用近红外吸收水的脉搏血氧饱和度信号校正
公开(公告)号：US08175670B2
公开(公告)日：2012-05-08
申请号：US11521960
申请日：2006-09-15
申请人： Clark R. Baker, Jr. , Edward Karst , Carine Hoarau
发明人： Clark R. Baker, Jr. , Edward Karst , Carine Hoarau
IPC分类号： A61B5/1455 , A61B5/02
CPC分类号： A61B5/7207 , A61B5/02416 , A61B5/14551
摘要： A method and system for measuring a physiological parameter, comprising collecting a first absorbance at a first wavelength, chosen to be primarily absorbed by water; collecting a second absorbance at a second wavelength, chosen to be primarily absorbed by hemoglobin; and combining the first signal and the second signal to generate a combined plethysmograph signal which is proportionate lower in noise caused by motion-related interference.
摘要翻译：一种用于测量生理参数的方法和系统，包括收集被选择为主要被水吸收的第一波长的第一吸光度; 收集第二波长的第二吸光度，其被选择为主要由血红蛋白吸收; 以及组合第一信号和第二信号以产生由运动相关干扰引起的噪声相对较低的组合体积描记器信号。

5. 发明授权

US07869850B2 Medical sensor for reducing motion artifacts and technique for using the same 有权
标题翻译：用于减少运动伪像的医疗传感器及其使用技术
公开(公告)号：US07869850B2
公开(公告)日：2011-01-11
申请号：US11241375
申请日：2005-09-29
申请人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
发明人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
IPC分类号： A61B5/1455
CPC分类号： A61B5/6886 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B5/6844 , Y10T29/49826
摘要： A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector.
摘要翻译：用于脉搏血氧饱和度测定的传感器或利用分光光度法的其它应用可适用于通过固定发射器和检测器之间的光学距离来减少运动伪影。柔性传感器设置有加强构件，以在应用于患者时将传感器的发射器和检测器保持在相对固定的位置。此外，环形或部分环形的传感器适于在施加到患者时将传感器的发射器和检测器保持在相对固定的位置。夹式传感器设置有间隔器，该间隔件控制发射器和检测器之间的距离。

6. 发明授权

US07650177B2 Medical sensor for reducing motion artifacts and technique for using the same 有权
标题翻译：用于减少运动伪像的医疗传感器及其使用技术
公开(公告)号：US07650177B2
公开(公告)日：2010-01-19
申请号：US11496869
申请日：2006-08-01
申请人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
发明人： Carine Hoarau , Clark R. Baker, Jr. , Edward Karst
IPC分类号： A61B5/1455
CPC分类号： A61B5/6886 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B5/6844 , Y10T29/49826
摘要： A sensor for pulse oximetry or other applications utilizing spectrophotometry may be adapted to reduce motion artifacts by fixing the optical distance between an emitter and detector. A flexible sensor is provided with a stiffening member to hold the emitter and detector of the sensor in a relatively fixed position when applied to a patient. Further, an annular or partially annular sensor is adapted to hold an emitter and detector of the sensor in a relatively fixed position when applied to a patient. A clip-style sensor is provided with a spacer that controls the distance between the emitter and detector.
摘要翻译：用于脉搏血氧饱和度测定的传感器或利用分光光度法的其它应用可适用于通过固定发射器和检测器之间的光学距离来减少运动伪影。柔性传感器设置有加强构件，以在应用于患者时将传感器的发射器和检测器保持在相对固定的位置。此外，环形或部分环形的传感器适于在施加到患者时将传感器的发射器和检测器保持在相对固定的位置。夹式传感器设置有间隔器，该间隔件控制发射器和检测器之间的距离。

7. 发明授权

US09801584B2 Method for detection of aberrant tissue spectra 有权
公开(公告)号：US09801584B2
公开(公告)日：2017-10-31
申请号：US13598312
申请日：2012-08-29
申请人： Clark R. Baker, Jr.
发明人： Clark R. Baker, Jr.
IPC分类号： A61B5/1455 , A61B5/00
CPC分类号： A61B5/6843 , A61B5/14551 , A61B5/14552 , A61B5/7203
摘要： A method is provided for determining contact of a sensor with a patient's tissue. The method comprises comparing the intensity of detected light at a first wavelength to a threshold, wherein the first wavelength is not used to determine a physiological characteristic of the patient, and determining if the sensor is in contact with the patient's tissue based on the comparison. In addition, a method is provided for determining the amount of light shunting during operation of the sensor. The method comprises comparing the intensity of detected light at a first wavelength to a threshold, wherein the first wavelength is not used to determine a physiological characteristic of the patient, and determining the amount of light shunting based on the comparison.

8. 发明授权

US08862194B2 Method for improved oxygen saturation estimation in the presence of noise 有权
标题翻译：在存在噪声的情况下改进氧饱和度估计的方法
公开(公告)号：US08862194B2
公开(公告)日：2014-10-14
申请号：US12165256
申请日：2008-06-30
申请人： Clark R. Baker, Jr.
发明人： Clark R. Baker, Jr.
IPC分类号： A61B5/00 , A61B5/1455
CPC分类号： A61B5/7203 , A61B5/14551 , A61B5/7264 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B5/7455
摘要： The present disclosure relates, according to some embodiments, to devices, systems, and methods for estimating a physiological parameter in the presence of noise. For example, the disclosure relates, in some embodiments, to devices, systems, and methods for assessing (e.g., estimating, measuring, calculating) oxygen saturation (SpO2). Methods of assessing SpO2 may include assessing a noise metric associated with motion artifact. In some embodiments, a percentage (e.g., an empirically determined percentage) of a noise metric may be simply added to the SpO2 estimate to produce a corrected SpO2 estimate. An oximetry algorithm may include, according to some embodiments, combining multiple internal SpO2 estimates and associated noise and/or signal quality metrics (e.g., using a radial basis neural network) to produce a modified (e.g., corrected) SpO2 estimate (e.g., rather than merely selecting the estimate from a finite number of candidates). A modified SpO2 estimate may include little or no movement-based error.
摘要翻译：根据一些实施例，本公开涉及用于在存在噪声的情况下估计生理参数的装置，系统和方法。例如，在一些实施例中，本公开涉及用于评估（例如，估计，测量，计算）氧饱和度（SpO2）的装置，系统和方法。评估SpO2的方法可能包括评估与运动伪影相关的噪声指标。在一些实施例中，噪声度量的百分比（例如经验确定的百分比）可以简单地添加到SpO2估计值以产生校正的SpO2估计。根据一些实施例，血氧测定算法可以包括组合多个内部SpO2估计和相关联的噪声和/或信号质量度量（例如，使用径向基神经网络）以产生经修改（例如，校正的）SpO2估计（例如，而不仅仅是从有限数量的候选人中选择估计）。修改的SpO2估计可能包括很少或没有基于运动的错误。

9. 发明授权

US08792949B2 Reducing nuisance alarms 有权
标题翻译：减少有害警报
公开(公告)号：US08792949B2
公开(公告)日：2014-07-29
申请号：US12399304
申请日：2009-03-06
申请人： Clark R. Baker, Jr.
发明人： Clark R. Baker, Jr.
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/14551 , A61B5/7221 , A61B5/746 , G06F19/00 , G06F19/3418 , G16H40/63
摘要： Embodiments disclosed herein may describe systems and methods for reducing nuisance alarms using probability and/or accuracy of a measured physiological parameter, such as the pulse rate or SpO2 measurement generated by a pulse oximeter. Embodiments may include methods for adjusting a predetermined alarm threshold based on the probability distribution of the estimated pulse rate and/or oxygen saturation of a patient's blood.
摘要翻译：本文公开的实施例可以描述使用测量的生理参数（例如由脉搏血氧计产生的脉搏率或SpO2测量）的概率和/或精度来减少麻烦警报的系统和方法。实施例可以包括基于患者血液的估计脉率和/或氧饱和度的概率分布来调整预定警报阈值的方法。

10. 发明授权

US08509869B2 Method and apparatus for detecting and analyzing variations in a physiologic parameter 失效
标题翻译：用于检测和分析生理参数变化的方法和装置
公开(公告)号：US08509869B2
公开(公告)日：2013-08-13
申请号：US12467003
申请日：2009-05-15
申请人： Clark R. Baker, Jr. , Paul D. Mannheimer
发明人： Clark R. Baker, Jr. , Paul D. Mannheimer
IPC分类号： A61B5/00
CPC分类号： A61B5/14551
摘要： The present disclosure is generally directed to identifying and/or analyzing high resolution variations in a measured physiologic parameter, such as blood oxygen saturation (SpO2) measured using pulse oximetry. Present embodiments may include a system including a sensor comprising an emitter capable of emitting light at different wavelengths into a tissue bed, and a detector capable of detecting the light from the emitter after dispersion and/or reflection by the tissue bed. Further, the system may include a pulse oximeter capable of receiving signals from the sensor that are indicative of characteristics of the light detected by the detector, and utilizing the signals to estimate blood oxygen saturation values over time at a high resolution to facilitate detection of variations in the blood oxygen saturation values that are smaller in magnitude than an accuracy, display precision, and/or calibration of the blood oxygen saturation values.
摘要翻译：本公开通常涉及鉴定和/或分析测量的生理参数中的高分辨率变化，例如使用脉搏血氧测定法测量的血氧饱和度（SpO2）。本实施例可以包括包括传感器的系统，该传感器包括能够将不同波长的光发射到组织床中的发射器，以及能够在由组织床分散和/或反射之后检测来自发射体的光的检测器。此外，该系统可以包括能够接收来自传感器的信号的脉搏血氧计，其指示由检测器检测到的光的特性，并且利用该信号以高分辨率随时间推定血氧饱和度值，以便于检测变化在血氧饱和度值的范围内比血氧饱和度值的精度，显示精度和/或校准更小。

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