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1. 发明申请

US20030165942A1 Compound, especially marker-dye, on the basis of polymethines 审中-公开
标题翻译：化合物，特别是标记染料，在聚甲基的基础上
公开(公告)号：US20030165942A1
公开(公告)日：2003-09-04
申请号：US10310206
申请日：2002-12-05
申请人： Dyomics GmbH
发明人： Peter Czerney , Matthias Wenzel , Bernd Schweder , Frank Lehmann
IPC分类号： C12Q001/68 , G01N033/53 , C07D517/02 , C07D417/02 , C07D413/02 , C07D43/02
CPC分类号： C09B23/105
摘要： The invention relates to fluorescent dyes (fluorophores) based on polymethines for use in optical measurement and detection procedures, in particular those employing fluorescence, for example in medicine, in pharmacology and in the biological, materials and environmental sciences. The objective was to create fluorophores based on polymethines that have a large Stokes shift, high photostability, long storage life and a high fluorescent quantum yield, and that can be excited in the simplest possible manner by white-light sources or laser radiation in the UV, visible or NIR spectral region. According to the invention dyes on the basis of polymethines having the general formulas I, II and III 1 are employed.
摘要翻译：本发明涉及基于用于光学测量和检测程序的聚甲基化的荧光染料（荧光团），特别是使用荧光的那些，例如在医学，药理学以及生物，材料和环境科学中。目的是基于具有大的斯托克斯位移，高光稳定性，长存储寿命和高荧光量子产率的聚甲基化产生荧光团，并且可以以最简单的方式通过白光源或UV中的激光辐射来激发荧光团，可见光或近红外光谱区。根据本发明，使用基于具有通式I，II和III的聚甲基化的染料。

2. 发明申请

US20040260093A1 Compound, especially marker-dye on the basis of polymethines 有权
标题翻译：化合物，特别是在聚甲基化的基础上的标记染料
公开(公告)号：US20040260093A1
公开(公告)日：2004-12-23
申请号：US10846789
申请日：2004-05-14
申请人： Dyomics GmbH
发明人： Peter Czerney , Matthias Wenzel , Bernd Schweder , Frank Lehmann
IPC分类号： C12Q001/68 , C07D41/02 , C07D43/02
CPC分类号： C09B23/107 , C09B57/02
摘要： The invention relates to fluorescent dyes (fluorophores) based on polymethines for use in optical measurement and detection procedures, in particular those employing fluorescence, for example in medicine, in pharmacology and in the biological, materials and environmental sciences. The objective was to create fluorophores based on polymethines that have a large Stokes shift, high photostability, long storage life and a high fluorescent quantum yield, and that can be excited in the simplest possible manner by white-light sources or laser radiation in the UV, visible or NIR spectral region. According to the invention dyes on the basis of polymethines having the general formulas I, II or III 1 are employed.
摘要翻译：本发明涉及基于用于光学测量和检测程序的聚甲基化的荧光染料（荧光团），特别是使用荧光的那些，例如在医学，药理学以及生物，材料和环境科学中。目的是基于具有大的斯托克斯位移，高光稳定性，长存储寿命和高荧光量子产率的聚甲基化产生荧光团，并且可以以最简单的方式通过白光源或UV中的激光辐射来激发荧光团，可见光或近红外光谱区。根据本发明，采用基于具有通式I，II或III的聚甲基的染料。

3. 发明申请

US20030045717A1 Compounds on the basis of 2 and 4-chromeenylidene-merocyaninese respectively, and their use 有权
标题翻译：基于2和4-二氯代亚铁菊酯的化合物及其用途
公开(公告)号：US20030045717A1
公开(公告)日：2003-03-06
申请号：US10190371
申请日：2002-07-03
申请人： Dyomics GmbH
发明人： Peter Czerney , Matthias Wenzel , Wilhelm Frank , Frank Lehmann
IPC分类号： C07D45/02
CPC分类号： C07D405/06 , C07D405/14 , C07D491/04 , C07F9/65586 , C09B23/0066 , C09B23/105 , C09B23/107
摘要： The invention relates to compounds based on merocyanines with the general formulas I and/or II, 1 where nnull0 or an integer from 1 to 3, XnullO or S and the residues R1 to R12 are the same or different and signify in particular hydrogen or various organic residues, without or with functional groups, and R2 incorporates an amine function. The compounds in accordance with the invention are suitable as fluorescent dyes (fluorophores) for used in optical determination and demonstration methods, in particular those employing fluorescence, for example in medicine, pharmacology and the biological, materials and environmental sciences. They are characterized by high photostability and long storage life, and exhibit a high fluorescence quantum yield. Excitation causing them to emit light can be achieved in a simple manner, by white-light sources or by laser irradiation in the UV, visible or NIR spectral region.
摘要翻译：本发明涉及基于具有通式I和/或II的部花青的化合物，其中n = 0或1至3的整数，X = O或S，残基R 1至R 12相同或不同，特别表示氢或各种有机残基，没有或具有官能团，并且R 2包含胺官能团。根据本发明的化合物适用于用于光学测定和显示方法的荧光染料（荧光团），特别是使用荧光的那些，例如在医学，药理学和生物，材料和环境科学中。它们的特征在于高的光稳定性和长的储存寿命，并表现出高的荧光量子产率。可以通过白光源或通过在UV，可见光或NIR光谱区域中的激光照射以简单的方式实现引起它们发光的激发。

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