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    • 3. 发明申请
    • Production Method for a Nanopatterned Epoxy Substrate
    • 纳米图案环氧基材的制备方法
    • US20110155591A1
    • 2011-06-30
    • US13056922
    • 2009-04-14
    • Kwang Hoe ChungSung Yu HongHyun Ju DohJin Sub ChoiJae Hoon LimSung Joong Kim
    • Kwang Hoe ChungSung Yu HongHyun Ju DohJin Sub ChoiJae Hoon LimSung Joong Kim
    • G01N27/30B29C33/38B05D5/12B32B38/00C23C14/14C23C16/06C23C14/34C25D5/56
    • G01N33/4905
    • Provided is a method for preparing an epoxy substrate having a nanopattern, including: (a) forming a titanium oxide film by anodizing a titanium substrate; (b) obtaining a titanium substrate having a concave shape formed on the surface by removing the titanium oxide film from the titanium substrate on which the titanium oxide film has been formed; (c) coating an epoxy resin onto the titanium substrate on which the concave shape has been formed; and (d) obtaining an epoxy substrate having a nanopattern of convex surfaces by removing the titanium substrate. According to the presently disclosed method, an epoxy substrate having a nanopattern of convex surfaces is prepared by anodizing a titanium substrate, coating an epoxy resin onto a nanopattern formed with a concave shape on the surface of the titanium substrate, and removing the titanium substrate. This straightforward process makes it possible to efficiently prepare an epoxy substrate having a nanopattern, which is fine and on the nano scale, for the measurement of blood coagulation. Further, the epoxy substrate prepared in accordance with the present disclosure makes it possible to efficiently use an electrochemical technique to ascertain whether or not blood coagulation is present in a blood sample.
    • 提供一种制备具有纳米图案的环氧树脂基板的方法,包括:(a)通过阳极氧化钛基板形成氧化钛膜; (b)从形成有氧化钛膜的钛基板除去氧化钛膜,得到表面形成有凹状的钛基板; (c)将环氧树脂涂布到已经形成凹形的钛基板上; 和(d)通过除去钛基材得到具有凸表面的纳米图案的环氧树脂基材。 根据目前公开的方法,通过对钛基板进行阳极氧化,在钛基板的表面上将环氧树脂涂布在形成为凹形的纳米图案上,并除去钛基板,来制备具有凸面的纳米图案的环氧树脂基板。 这种简单的方法使得可以有效地制备具有细小且纳米尺度的纳米图案用于测量血液凝固的环氧树脂基材。 此外,根据本公开制备的环氧树脂基材使得可以有效地使用电化学技术来确定血液样品中是否存在凝血。