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1. 发明申请

US20080114427A1 SYSTEM FOR PROVIDING HEAT TREATMENT AND HEAT LOSS REDUCTION FOR TREATING MEIBOMIAN GLAND DYSFUNCTION 有权
标题翻译：用于治疗脑血管功能障碍的热处理和热量减少系统
公开(公告)号：US20080114427A1
公开(公告)日：2008-05-15
申请号：US12015721
申请日：2008-01-17
申请人： Donald Korb , Stephen Grenon , Timothy Willis , John Jans
发明人： Donald Korb , Stephen Grenon , Timothy Willis , John Jans
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61B18/12 , A61B2017/00084 , A61B2018/046 , A61B2018/048 , A61F7/007 , A61F9/00772 , A61F2007/0004 , A61F2007/0059 , A61H7/00 , A61H2015/0014 , A61N7/00
摘要： A system for treating meibomian gland dysfunction. A controller controls heat applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force is also applied to tissue proximate the patient's meibomian glands during the application of heat to improve conductive heat transfer and reduce blood flow in tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands. Reducing the amount of time to reached desired temperature levels an aid in reducing discomfort to the patient during treatment.
摘要翻译：治疗睑板腺功能障碍的系统。控制器控制施加到患者睑板腺附近的组织的热量，以向睑板腺提供导电热传递。热的应用有助于睑板腺中阻塞或闭塞的表达，以恢复足够的脂质流向脂质层以治疗干眼症。在施加热量的同时，还将力施加到患者睑板腺附近的组织以改善导电传热并减少导致对流热损失的组织中的血流。因此，施加力可以进一步增加温度水平和/或减少达到期望温度水平以消除障碍物的时间。达到升高的温度水平可能会改善睑板腺的阻塞或闭塞的融化，松动或软化。减少达到所需温度水平的时间量，有助于减轻治疗期间患者的不适。

2. 发明申请

US20080114422A1 HEAT TREATMENT AND HEAT LOSS REDUCTION FOR TREATING MEIBOMIAN GLAND DYSFUNCTION 有权
标题翻译：治疗脑血管功能障碍的热处理和热损失
公开(公告)号：US20080114422A1
公开(公告)日：2008-05-15
申请号：US12015584
申请日：2008-01-17
申请人： Donald Korb , Stephen Grenon , Timothy Willis , John Jans
发明人： Donald Korb , Stephen Grenon , Timothy Willis , John Jans
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61B18/12 , A61B2017/00084 , A61B2018/046 , A61B2018/048 , A61F7/007 , A61F9/00772 , A61F2007/0004 , A61F2007/0059 , A61H7/00 , A61H2015/0014 , A61N7/00
摘要： A method of treating meibomian gland dysfunction. Heat is applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the tissue proximate the patient's meibomian glands to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
摘要翻译：治疗睑板腺功能障碍的方法。将热量施加到患者睑板腺附近的组织，以向睑板腺提供导电热传递。热的应用有助于睑板腺中阻塞或闭塞的表达，以恢复足够的脂质流向脂质层以治疗干眼症。也可以将力施加到患者睑板腺附近的组织，以改善传导性热传递并减少组织中造成对流热损失的血液流动。因此，施加力可以进一步增加温度水平和/或减少达到期望温度水平以消除障碍物的时间。达到升高的温度水平可以改善睑板腺中的阻塞物或闭塞的熔化，松动或软化，同时减少达到所需温度水平的时间量和/或有助于减轻治疗期间患者的不适。

3. 发明申请

US20080114424A1 SYSTEM FOR INNER EYELID TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION 有权
标题翻译：内镜治疗脑血管性功能障碍的系统
公开(公告)号：US20080114424A1
公开(公告)日：2008-05-15
申请号：US12015600
申请日：2008-01-17
申请人： Stephen Grenon , John Jans , Jordan Hutchinson , Keith Gausmann
发明人： Stephen Grenon , John Jans , Jordan Hutchinson , Keith Gausmann
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61B18/12 , A61B2017/00084 , A61B2018/046 , A61B2018/048 , A61F7/007 , A61F9/00772 , A61F2007/0004 , A61F2007/0059 , A61H7/00 , A61H2015/0014 , A61N7/00
摘要： A system for treating meibomian gland dysfunction. A controller controls a lid warmer attached onto a patient's eye to generate heat on the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. An eyecup may be employed to generate a force on the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
摘要翻译：治疗睑板腺功能障碍的系统。控制器控制附着在患者眼睛上的盖子加热器，以在眼睑内部产生热量，以向睑板腺提供导电热传递。热的应用有助于睑板腺中阻塞或闭塞的表达，以恢复足够的脂质流向脂质层以治疗干眼症。在加热眼睑内部时，睑板腺的温度可以更快速有效地达到所需水平。达到更高的温度水平可能有助于消除睑板腺中的障碍物。当向眼睑内部施加热量时，也可能需要较少的时间达到所需的温度水平。可以使用眼罩在患者眼皮的外侧产生力，以改善导电热传递并减少引起对流热损失的眼睑中的血流。因此，施加力可以进一步增加温度水平和/或减少达到期望温度水平以消除障碍物的时间。

4. 发明申请

US20080114423A1 APPARATUS FOR INNER EYELID TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION 审中-公开
标题翻译：用于内镜治疗脑血管性功能障碍的装置
公开(公告)号：US20080114423A1
公开(公告)日：2008-05-15
申请号：US12015593
申请日：2008-01-17
申请人： Stephen Grenon , John Jans , Jordan Hutchinson , Keith Gausmann
发明人： Stephen Grenon , John Jans , Jordan Hutchinson , Keith Gausmann
IPC分类号： A61F7/12
CPC分类号： A61F9/00772 , A61B17/22 , A61B18/08 , A61B18/12 , A61B2017/00084 , A61B2017/22082 , A61B2018/046 , A61B2018/048 , A61F7/007 , A61F7/02 , A61F7/12 , A61F2007/0004 , A61F2007/0059 , A61F2007/0071 , A61F2007/0086 , A61F2007/0091 , A61F2007/0096 , A61F2007/0249 , A61F2007/0282 , A61H7/00 , A61H2015/0014 , A61N7/00
摘要： An apparatus for treating meibomian gland dysfunction. A lid warmer may be attached onto a patient's eye to apply heat on the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. An eyecup may also be employed to generate a force on the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
摘要翻译：一种治疗睑板腺功能障碍的装置。盖子加热器可以附着在患者的眼睛上以在眼睑内部施加热量，以向睑板腺提供导电热传递。热的应用有助于睑板腺中阻塞或闭塞的表达，以恢复足够的脂质流向脂质层以治疗干眼症。在加热眼睑内部时，睑板腺的温度可以更快速有效地达到所需水平。达到更高的温度水平可能有助于消除睑板腺中的障碍物。当向眼睑内部施加热量时，也可能需要较少的时间达到所需的温度水平。还可以使用眼罩在患者眼皮的外侧产生力以改善导电传热并减少引起对流热损失的眼睑中的血流。因此，施加力可以进一步增加温度水平和/或减少达到期望温度水平以消除障碍物的时间。

5. 发明申请

US20100127474A1 Pivoting motorcycle footpeg 审中-公开
标题翻译：旋转摩托车脚g
公开(公告)号：US20100127474A1
公开(公告)日：2010-05-27
申请号：US12313573
申请日：2008-11-21
申请人： John Jans
发明人： John Jans
IPC分类号： B62J25/00
CPC分类号： B62J25/00
摘要： A tortion bar powered partially rotatable footpeg for a motorcycle.
摘要翻译：一个弯曲杆为摩托车提供部分旋转的脚蹬。

6. 发明申请

US20090043365A1 METHODS, APPARATUSES, AND SYSTEMS FOR REDUCING INTRAOCULAR PRESSURE AS A MEANS OF PREVENTING OR TREATING OPEN-ANGLE GLAUCOMA 审中-公开
标题翻译：用于减少眼压的方法，装置和系统作为预防或治疗开放性角膜炎的手段
公开(公告)号：US20090043365A1
公开(公告)日：2009-02-12
申请号：US12246071
申请日：2008-10-06
申请人： Beth Friedland , Donald R. Korb , Steve Grenon , John Jans , Keith Gausmann , Timothy R. Willis
发明人： Beth Friedland , Donald R. Korb , Steve Grenon , John Jans , Keith Gausmann , Timothy R. Willis
IPC分类号： A61F7/00
CPC分类号： A61B18/04 , A61B18/10 , A61B2018/00642 , A61B2018/00791 , A61B2018/046 , A61B2018/048 , A61F9/00781 , A61F2007/0004 , A61F2007/0059 , A61F2007/0071 , A61H1/008 , A61N7/00
摘要： Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (IOP) in a patient to either prevent or treat open-angle glaucoma. Heat is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT). By loosening or relaxing clogs or other inhibitors in the trabecular meshwork, the outflow path for aqueous humor is increased or restored, which can lower IOP and either prevent or treat glaucoma. Force may also be applied to the patient's eye to apply pressure to the trabecular meshwork to further assist in the loosening or relaxing of clogs or other inhibitors in the trabecular meshwork.
摘要翻译：实施方案包括用于降低患者眼内压升高（IOP）以预防或治疗开角型青光眼的方法，装置和系统。热量被施加到患者眼睛中的小梁网，而不损伤小梁网中的蛋白质。对小梁网应用热量具有放松或松动小梁网中的蛋白质堵塞物或其他抑制剂的作用，其减少或阻碍房水流出，从而增加患者的眼压并引起眼高压（OHT）。通过在小梁网中松动或松弛堵塞物或其他抑制剂，房水的流出路径增加或恢复，这可以降低IOP并预防或治疗青光眼。力也可以应用于患者的眼睛，以向小梁网施加压力，以进一步协助松动或松弛小梁网中的堵塞物或其它抑制剂。

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