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1. 发明授权

US5697380A Guide wire having distal extremity with adjustable support characteristic and method 失效
标题翻译：导丝具有远端，具有可调支撑特性和方法
公开(公告)号：US5697380A
公开(公告)日：1997-12-16
申请号：US585885
申请日：1996-01-11
申请人： Dignah B. Quiachon , Deepak R. Gandhi , Dennis L. Brooks , Mir A. Imran , Roger J. Guidi
发明人： Dignah B. Quiachon , Deepak R. Gandhi , Dennis L. Brooks , Mir A. Imran , Roger J. Guidi
IPC分类号： A61F11/00 , A61M25/00 , A61M25/09 , A61M29/00
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/0915 , A61M2025/09158 , A61M2025/09175
摘要： A guide wire having a distal extremity with an adjustable support characteristic comprising a core wire having proximal and distal extremities. The distal extremity has a reduced cross sectional area which is more flexible than the proximal extremity. A tip secured to the distal extremity of the core wire. A sleeve of superelastic material is disposed coaxially on the distal extremity of the core wire. The sleeve is annealed so that it is relatively flexible at a temperature ranging from 20.degree. to 40.degree. C. and becomes progressively stiffer as temperature increases. The core wire conducts electrical energy to the superelastic sleeve to supply heat to the sleeve and extends from the proximal extremity of the core wire to the sleeve to cause the sleeve to become stiffer to thereby increase the stiffness of the distal extremity of the guide wire. A guide wire is provided having a distal extremity with an adjustable support characteristic which varies from a floppy characteristic to a stiff characteristic.
摘要翻译：一种具有远端的引导线，其具有可调节的支撑特征，包括具有近端和远端的芯线。远端具有减小的横截面积，其比近端更灵活。尖端固定在芯线的远端。超弹性材料的套筒同轴地设置在芯线的远端上。套管退火，使其在20°至40°C的温度范围内具有相对的柔韧性，随着温度升高而逐渐变硬。芯线将电能传导到超弹性套管以向套管供热并且从芯线的近端延伸到套筒以使套筒变得更硬，从而增加导丝的远端的刚度。提供导丝，其具有远端，具有可调整的支撑特性，其从软盘特性变为刚性特征。

2. 发明授权

US5938623A Guide wire with adjustable stiffness 失效
标题翻译：导丝可调刚度
公开(公告)号：US5938623A
公开(公告)日：1999-08-17
申请号：US780687
申请日：1997-01-08
申请人： Dignah B. Quiachon , Robert A. Guziak , Dennis L. Brooks , Deepak R. Gandhi , Mir A. Imran , Roger J. Guidi
发明人： Dignah B. Quiachon , Robert A. Guziak , Dennis L. Brooks , Deepak R. Gandhi , Mir A. Imran , Roger J. Guidi
IPC分类号： A61M25/00 , A61M25/09 , H04L7/00 , H04L25/14 , A61B5/00
CPC分类号： H04L7/0008 , A61M25/09 , H04L25/14 , A61M2025/0063 , A61M2025/09133 , A61M2025/0915 , A61M2025/09158 , A61M25/0054
摘要： Guide wire for use in a medical procedure and for use with a power supply comprising a solid core wire having proximal and distal extremities. The proximal extremity has a predetermined diameter. At least a portion of the distal extremity has a reduced size with respect to the predetermined diameter. A flexible coil is secured to the distal extremity of the core wire and extends over the portion of the core wire having a reduced size. An actuator member is disposed proximal of the coil and extends along the core wire. Electrical conductors extend from the proximal extremity of the core wire to the actuator member for supplying heat to the actuator member. The actuator member is formed of a temperature activated metal alloy having a Young's modulus of 4.times.10.sup.6 to 14.times.10.sup.6 psi which increases in stiffness when heat is supplied thereto to increase the stiffness of the guide wire proximally of the coil.
摘要翻译：导线，用于医疗程序并用于电源，包括具有近端和远端的实心芯线。近端具有预定的直径。远端末端的至少一部分相对于预定直径具有减小的尺寸。柔性线圈固定到芯线的远端，并且在具有减小尺寸的芯线的部分上延伸。致动器构件设置在线圈的近侧并且沿着芯线延伸。电导体从芯线的近端延伸到致动器构件，以向致动器构件供热。致动器构件由具有4×10 6至14×10 6 psi的杨氏模量的温度活化金属合金形成，当向其供应热量时，刚度增加，从而增加导线在线圈近侧的刚度。

3. 发明授权

US6039743A Guide wire having distal extremity with adjustable support characteristic and method 失效
标题翻译：导丝具有远端，具有可调支撑特性和方法
公开(公告)号：US6039743A
公开(公告)日：2000-03-21
申请号：US902772
申请日：1997-07-30
申请人： Dignah B. Quiachon , Deepak R. Gandhi , Dennis L. Brooks , Mir A. Imran , Roger J. Guidi
发明人： Dignah B. Quiachon , Deepak R. Gandhi , Dennis L. Brooks , Mir A. Imran , Roger J. Guidi
IPC分类号： A61F11/00 , A61M25/00 , A61M25/09 , A61M29/00
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/0915 , A61M2025/09158 , A61M2025/09175
摘要： A guide wire having a distal extremity with an adjustable support characteristic including a core wire having proximal and distal extremities. The distal extremity has a reduced cross sectional area which is more flexible than the proximal extremity. A tip is secured to the distal extremity of the core wire. A sleeve of superelastic material is disposed coaxially on the distal extremity of the core wire. The sleeve is annealed so that it is relatively flexible at a temperature ranging from 20.degree. to 40.degree. C. and becomes progressively stiffer as temperature increases. The core wire conducts electrical energy to the superelastic sleeve to supply heat to the sleeve and extends from the proximal extremity of the core wire to the sleeve to cause the sleeve to become stiffer to thereby increase the stiffness of the distal extremity of the guide wire. A guide wire is provided having a distal extremity with an adjustable support characteristic which varies from a floppy characteristic to a stiff characteristic.
摘要翻译：一种具有远端的引导线，其具有可调节的支撑特征，包括具有近端和远端的芯线。远端具有减小的横截面积，其比近端更灵活。尖端被固定到芯线的远端。超弹性材料的套筒同轴地设置在芯线的远端上。套管退火，使其在20°至40°C的温度范围内具有相对的柔韧性，随着温度升高而逐渐变硬。芯线将电能传导到超弹性套管以向套管供热并且从芯线的近端延伸到套筒以使套筒变得更硬，从而增加导丝的远端的刚度。提供导丝，其具有远端，具有可调整的支撑特性，其从软盘特性变为刚性特征。

4. 发明授权

US5520645A Low profile angioplasty catheter and/or guide wire and method 失效
标题翻译：低剖面血管成形术导管和/或导丝及方法
公开(公告)号：US5520645A
公开(公告)日：1996-05-28
申请号：US331217
申请日：1994-10-28
申请人： Mir A. Imran , Deepak R. Gandhi , Dennis L. Brooks
发明人： Mir A. Imran , Deepak R. Gandhi , Dennis L. Brooks
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02 , A61M37/00
CPC分类号： A61M25/0158 , A61M25/0097 , A61M25/104 , A61M2025/0186 , A61M2025/1079 , A61M2025/1093
摘要： A low profile balloon-on-a-wire catheter having a flexible elongate tubular member with proximal and distal extremities and with a lumen extending from the proximal extremity to the distal extremity. An inflatable balloon is mounted on the distal extremity of the flexible elongate tubular member. Communication is established between the lumen and the interior of the inflatable balloon. An inflation fitting is removably secured to the proximal extremity of the flexible elongate tubular member for supplying an inflation fluid to the lumen for inflating and deflating the balloon. The inflation fitting when removed provides a proximal extremity on the catheter which is free of obstructions so that another balloon catheter can be advanced over the proximal extremity of the flexible elongate tubular member.
摘要翻译：一种低剖面气球在线导管，其具有柔性细长管状构件，其具有近端和远端，并且具有从近端至远端延伸的内腔。可膨胀气囊安装在柔性细长管状构件的远端上。在可充气气囊的内腔和内部之间建立通信。膨胀配件可移除地固定到柔性细长管状构件的近端，用于将充气流体供应到管腔以使气囊膨胀和放气。当去除时的充气接头提供导管上的近端，其没有障碍物，使得另一气囊导管可以在柔性细长管状构件的近端延伸越过。

5. 发明授权

US5666968A Flexible guide wire with extension capability and guide wire extension for use therewith 失效
标题翻译：具有延伸能力的柔性导丝和与其一起使用的导丝延伸
公开(公告)号：US5666968A
公开(公告)日：1997-09-16
申请号：US405882
申请日：1995-03-17
申请人： Mir A. Imran , Dennis L. Brooks , Deepak R. Gandhi
发明人： Mir A. Imran , Dennis L. Brooks , Deepak R. Gandhi
IPC分类号： A61M25/01 , A61M25/09 , A61B5/00
CPC分类号： A61M25/01 , A61M25/0905
摘要： A guide wire with extension capability for use in a medical procedure having a guide wire and a guide wire extension. The guide wire comprises a flexible elongate cylindrical member having proximal and distal extremities. A portion of the distal extremity is formed of a material having high torquability and high pushability. The guide wire extension comprises a flexible elongate cylindrical member formed of a shape memory material. A major portion of the flexible elongate cylindrical member of the guide wire extension has a shape memory in the form of a coil so that when it is free it will assume a shape memory coil. A junction is formed between the proximal extremity of the guide wire and the distal extremity of the guide wire extension for connection of the guide wire extension to the guide wire.
摘要翻译：具有延伸能力的导丝，用于具有导丝和导丝延伸的医疗过程中。导丝包括具有近端和远端的柔性细长圆筒形构件。远端的一部分由具有高扭矩和高推力性的材料形成。导丝延伸部包括由形状记忆材料形成的柔性细长圆柱形构件。导丝延伸件的柔性细长圆柱形构件的主要部分具有线圈形式的形状记忆，使得当其自由时，其将呈现形状记忆线圈。在引导线的近端和导丝延伸部的远端之间形成有接头，用于将导丝延伸部与导丝连接。

6. 发明授权

US5779688A Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method 失效
标题翻译：薄型气球在线导管，具有可塑和/或可偏转的尖端和方法
公开(公告)号：US5779688A
公开(公告)日：1998-07-14
申请号：US504927
申请日：1995-07-20
申请人： Mir A. Imran , Cecily M. Hillsman , Deepak R. Gandhi , Dennis L. Brooks
发明人： Mir A. Imran , Cecily M. Hillsman , Deepak R. Gandhi , Dennis L. Brooks
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02
CPC分类号： A61M25/0158 , A61M25/0097 , A61M25/104 , A61M2025/0186 , A61M2025/1079 , A61M2025/1093
摘要： A low profile, balloon-on-a-wire catheter comprising a flexible elongate tubular member having proximal and distal extremities. A balloon inflation-deflation lumen extends from the proximal extremity to the distal extremity. An inflatable balloon is carried by the distal extremity of the flexible elongate tubular member. The flexible elongate tubular member carries means which establishes communication between the lumen and the interior of the inflatable balloon. A removable inflation device is removably secured to the proximal extremity of the flexible elongate tubular member for supplying an inflation fluid to the lumen for inflating and deflating the balloon. The removable inflation device forms a high pressure seal with the proximal extremity of the flexible elongate tubular member. The removable inflation device is free of obstructions so that another balloon catheter can be advanced over the proximal extremity of the flexible elongate tubular member which serves as a stand-alone guide wire. The distal extremity of the catheter is formed so that it is mechanically shapeable or can be electrically deflectable to facilitate steering of the distal extremity.
摘要翻译：一种薄型气球在线导管，其包括具有近端和远端的柔性细长管状构件。气球充气 - 通气腔从近端延伸到远端。可膨胀气囊由柔性细长管状构件的远端承载。柔性细长管状构件承载建立管腔和可充气气囊内部之间的连通的装置。可移除的充气装置可移除地固定到柔性细长管状构件的近端，用于向腔内供应充气流体以使气囊膨胀和放气。可移除的充气装置与柔性细长管状构件的近端形成高压密封。可移除的充气装置没有障碍物，使得另一个气囊导管可以在用作独立导丝的柔性细长管状构件的近端上前进。导管的远端被形成为使得其可机械地成形或可以电可偏转以便于远端的转向。

7. 发明授权

US5908405A Low profile balloon-on-a-wire catheter with shapeable and/or deflectable tip and method 失效
标题翻译：薄型气球在线导管，具有可塑和/或可偏转的尖端和方法
公开(公告)号：US5908405A
公开(公告)日：1999-06-01
申请号：US876999
申请日：1997-06-16
申请人： Mir A. Imran , Cecily M. Hillsman , Deepak R. Ghandi , Dennis L. Brooks
发明人： Mir A. Imran , Cecily M. Hillsman , Deepak R. Ghandi , Dennis L. Brooks
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02 , A61M31/00
CPC分类号： A61M25/0158 , A61M25/0097 , A61M25/104 , A61M2025/0186 , A61M2025/1079 , A61M2025/1093
摘要： A method for performing an angioplasty procedure for treating one or more stenoses in a blood vessel and branches thereof of a patient using a low profile balloon-on-a-wire catheter which has a flexible elongate tubular member with proximal and distal extremities and a removable inflation device removably secured to the proximal extremity of the flexible elongate tubular member. The method comprises the steps of inserting the balloon-on-a-wire catheter into the vessel so that the balloon is disposed in a selected stenosis in the vessel. The removable inflation device is placed on the proximal extremity of the flexible elongate tubular member so that it is in communication with the lumen in the flexible elongate tubular member. The balloon is inflated to create an enlarged flow passage through the selected stenosis. The removable inflation device is removed from the proximal extremity of the flexible elongate tubular member. A balloon catheter is introduced over the flexible elongate tubular member utilizing the flexible elongate tubular member as a stand-alone guide wire for guiding the balloon of the balloon catheter into the selected stenosis while the balloon of the balloon-on-a-wire catheter is deflated. The balloon of the balloon catheter is inflated to create a larger flow passage in the stenosis.
摘要翻译：一种执行血管成形术程序的方法，用于使用具有近端和远端四周的柔性细长管状构件的薄型气球在线导管来治疗患者的血管中的一个或多个狭窄及其分支，充气装置可移除地固定到柔性细长管状构件的近端。该方法包括以下步骤：将球形球形导管插入容器中，使得球囊以选定的狭窄处置于容器中。可移除的充气装置被放置在柔性细长管状构件的近端上，使得其与柔性细长管状构件中的内腔连通。气囊膨胀以产生通过所选狭窄的扩大的流动通道。可移除的充气装置从柔性细长管状构件的近端移除。使用柔性细长管状构件将气囊导管引导到柔性细长管状构件上，作为独立引导线，用于将球囊导管的气囊引导到所选择的狭窄中，而球形球形导管的气囊是瘪。气囊导管的气囊膨胀以在狭窄中产生较大的流动通道。

8. 发明授权

US06716231B1 Distal protection device 失效
标题翻译：远端保护装置
公开(公告)号：US06716231B1
公开(公告)日：2004-04-06
申请号：US09578244
申请日：2000-05-24
申请人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
发明人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： The present invention is a distal protection device for use during a vascular treatment, such as angioplasty or atherectomy. A filter assembly located on the distal end of a delivery member is deployed distally of the vascular region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.
摘要翻译：本发明是一种用于血管成形术或粥样斑块切除术的血管治疗期间的远端保护装置。位于递送构件的远端上的过滤器组件被展开在待治疗的血管区域的远端以捕获在手术期间和之后立即释放的栓塞。然后将过滤器缩回以保留任何捕获的栓塞，然后从患者中取出。

9. 发明授权

US06520988B1 Endolumenal prosthesis and method of use in bifurcation regions of body lumens 失效
标题翻译：腔内假体及其在体腔分叉区域的使用方法
公开(公告)号：US06520988B1
公开(公告)日：2003-02-18
申请号：US08937130
申请日：1997-09-24
申请人： Antonio Colombo , Robert D. Lashinski , Matthew J. Birdsall , Dennis L. Brooks , Philip J. Haarstad , James C. Peacock, III
发明人： Antonio Colombo , Robert D. Lashinski , Matthew J. Birdsall , Dennis L. Brooks , Philip J. Haarstad , James C. Peacock, III
IPC分类号： A61F206
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/91541 , A61F2002/91558 , A61F2250/0039
摘要： An endolumenal medical device assembly is provided for use in a bifurcation region of a body lumen. An expandable prosthesis, such as a stent, is included in the assembly and is adjustable from a radially collapsed condition to a radially expanded condition. The expandable prosthesis includes a prosthesis passageway and a side port. A dilator or an access device is engaged within the prosthesis passageway and also through the side port while the expandable prosthesis is in the radially collapsed condition. The expandable prosthesis may be positioned in the bifurcation region such that its distal end portion is in a first branch lumen extending from the bifurcation, its proximal end portion is in a common proximal lumen of the bifurcation region, and the side port is aligned with an entrance zone to a second branch lumen extending from the bifurcation. When the expandable prosthesis is so positioned the access device maintains percutaneous translumenal access to the second branch lumen through the prosthesis passageway and the side port while the expandable prosthesis is adjusted from the radially collapsed condition to the radially expanded condition. A dilator may also to expand the bore formed by the side port from an initial inner diameter to a larger expanded inner diameter. A second, lateral expandable prosthesis can also be coupled to the first expandable prosthesis at a location adjacent to the side port and engaged by the dilator or access device extending through the side port.
摘要翻译：提供了一种用于体腔分叉区域的腔内医疗装置组件。可扩张假体，例如支架，被包括在组件中，并且可以从径向塌陷状态调节到径向扩张状态。可扩张假体包括假体通道和侧端口。扩张器或进入装置接合在假体通道内并且还可以通过侧端口，而可扩张假体处于径向折叠状态。可扩张假体可以位于分叉区域中，使得其远端部分处于从分叉延伸的第一分支腔中，其近端部分位于分叉区域的共同的近侧内腔中，并且侧端口与入口区到从分叉延伸的第二分支腔。当可扩张假体如此定位时，进入装置通过假体通道和侧端口保持对第二分支腔的经皮腔内通路，同时将可扩张假体从径向折叠状态调节到径向扩张状态。扩张器还可以将由侧口形成的孔从初始内径扩大到较大的扩大内径。第二横向可膨胀假体还可以在与侧端口相邻的位置处联接到第一可扩张假体，并且通过延伸穿过侧端口的扩张器或进入装置接合。

10. 发明授权

US06457995B1 Vehicle fuse block extenders 失效
标题翻译：车辆保险丝座延长器
公开(公告)号：US06457995B1
公开(公告)日：2002-10-01
申请号：US09798022
申请日：2001-03-02
申请人： Dennis L. Brooks
发明人： Dennis L. Brooks
IPC分类号： H01R1368
CPC分类号： H01R13/68 , H01R13/115
摘要： The fuse block extenders are made up of a shell (10), (10a), (10b), (10c), (10d), (10e) enclosing a bus electrode (11), circuit electrode (12), (12a), electrode base(s) (13), (13a), (13b) and accessory electrode(s) (17), (17a), (17b), (17c). Some models have a detachable cover (21) and attached cover (21a), (21b), (21c), (21d) for the accessory electrodes. The bus electrode and circuit electrodes mate with complementary fuse block electrodes of appropriate capacities and shape and the accessory electrodes connect to the electrodes of accessory circuits.
摘要翻译：保险丝盒延长器由围绕总线电极（11），电路电极（12），（12a）的外壳（10），（10a），（10b），（10c），（10d），（10e），电极基体（13），（13a），（13b）和辅助电极（17），（17a），（17b），（17c）。一些型号具有用于辅助电极的可拆卸盖（21）和附接盖（21a），（21b），（21c），（21d）。总线电极和电路电极与适当容量和形状的互补熔断器电极配合，辅助电极连接到附件电路的电极。

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