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    • 1. 发明授权
    • Chip level waveguide sensor
    • 芯片级波导传感器
    • US5737457A
    • 1998-04-07
    • US587231
    • 1996-01-16
    • Devinder P. SainiStanley M. KlainerStephen L. Coulter
    • Devinder P. SainiStanley M. KlainerStephen L. Coulter
    • G01N21/43G01N21/77G02B6/42G02B6/43G02B6/00
    • G02B6/43G01N21/431G01N21/7703G02B6/42
    • Waveguide sensors are formed on a chip package which contains at least one source and at least one detector. Simple waveguide elements are mounted on the chip. Waveguide defining elements can also be formed integrally with the chip package so that simple waveguide bodies can be inserted or removed. Various geometries of source, reference detector, and sensing detector can be produced. A liquid waveguide sensor is formed by filling a waveguide channel with a liquid reagent or reagents homogeneously dispersed in sol-gels. Sensing waveguides are made of or contain chemistries or biochemistries or are uncoated. Reference waveguides are made of or contain chemistries, biochemistries or materials which are inert to the analyte (sample) of interest. The chip geometries are such that absorption, fluorescence, and refractive index measurements can be made.
    • 波导传感器形成在包含至少一个源和至少一个检测器的芯片封装上。 简单的波导元件安装在芯片上。 波导限定元件也可以与芯片封装一体地形成,从而可以插入或移除简单的波导体。 可以生产源,参考检测器和感测检测器的各种几何形状。 通过用均匀分散在溶胶中的液体试剂或试剂填充波导通道来形成液体波导传感器。 传感波导由化学物质或生物化学物质制成或包含或未被涂覆。 参考波导由对感兴趣的分析物(样品)是惰性的化学物质,生物化学物质或材料制成或包含。 芯片的几何形状使得可以进行吸收,荧光和折射率测量。