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1. 发明授权

US06573040B2 Patterned binding of functionalized microspheres for optical diffraction-based biosensors 有权
$Patterned binding of functionalized microspheres for optical diffraction-based biosensors$
标题翻译：用于光学衍射的生物传感器的官能化微球的图案化结合
公开(公告)号：US06573040B2
公开(公告)日：2003-06-03
申请号：US09733204
申请日：2000-12-08
申请人： Dennis S. Everhart , Rosann M. Kaylor , Kevin McGrath
发明人： Dennis S. Everhart , Rosann M. Kaylor , Kevin McGrath
IPC分类号： G01N33567
CPC分类号： G01N33/54346 , B01J2219/00382 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , C40B60/14 , G01N21/4788 , G01N33/54373 , G01N33/553
摘要： The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.
摘要翻译：本发明提供了用于检测介质中存在的分析物的廉价且敏感的系统和方法。该系统包括衍射增强元件，例如功能化微球，其被修饰使得它们能够与靶分析物结合。此外，该系统包括聚合物膜，其可以包括金属涂层，在其上印刷特定的预定图案的分析物特异性受体。当将目标分析物直接或与衍射增强元件连接到聚合物膜的选择区域时，透射和/或反射光的衍射通过物理尺寸和限定的精确放置分析物而发生。产生可以用眼睛或可选地用感测装置容易地看到的衍射图像。

2. 发明授权

US06579673B2 Patterned deposition of antibody binding protein for optical diffraction-based biosensors 有权
$Patterned deposition of antibody binding protein for optical diffraction-based biosensors$
标题翻译：用于光学衍射的生物传感器的抗体结合蛋白的图案沉积
公开(公告)号：US06579673B2
公开(公告)日：2003-06-17
申请号：US09213713
申请日：1998-12-17
申请人： Kevin McGrath , Rosann M. Kaylor , Dennis S. Everhart
发明人： Kevin McGrath , Rosann M. Kaylor , Dennis S. Everhart
IPC分类号： G01N33543
CPC分类号： G01N21/4788 , B01J19/0046 , B01J2219/00382 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , B01J2219/00707 , C40B60/14 , G01N33/54353 , G01N33/54373 , Y10S435/817 , Y10S436/805 , Y10S436/807
摘要： The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is printed a specific, predetermined pattern of an antibody-binding proteins. Upon attachment of a target analyte to select areas of the plastic film upon which the protein is printed, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.
摘要翻译：本发明提供了用于检测和定量存在于介质中的分析物的廉价且敏感的装置和方法。该装置包括金属化膜，在其上印刷特定的预定图案的抗体结合蛋白。当将目标分析物附着到选择蛋白质印刷的塑料膜的区域时，通过物理尺寸和分析物的精确放置进行发射和/或反射光的衍射。产生可以用眼睛或可选地用感测装置容易地看到的衍射图像。

3. 发明授权

US06221579B1 Patterned binding of functionalized microspheres for optical diffraction-based biosensors 有权
$Patterned binding of functionalized microspheres for optical diffraction-based biosensors$
公开(公告)号：US06221579B1
公开(公告)日：2001-04-24
申请号：US09210016
申请日：1998-12-11
申请人： Dennis S. Everhart , Rosann M. Kaylor , Kevin McGrath
发明人： Dennis S. Everhart , Rosann M. Kaylor , Kevin McGrath
IPC分类号： G01N33567
CPC分类号： G01N33/54346 , B01J2219/00382 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , C40B60/14 , G01N21/4788 , G01N33/54373 , G01N33/553
摘要： The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.

4. 发明授权

US09329893B2 Method for resuming an APD wavefront in which a subset of elements have faulted 有权
标题翻译：恢复其中元素子集发生故障的APD波前的方法
公开(公告)号：US09329893B2
公开(公告)日：2016-05-03
申请号：US13325298
申请日：2011-12-14
申请人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas R. Woller , Kevin McGrath , Sebastien Nussbaum , Nuwan Jayasena , Rex McCrary , Philip J. Rogers , Mark Leather
发明人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas R. Woller , Kevin McGrath , Sebastien Nussbaum , Nuwan Jayasena , Rex McCrary , Philip J. Rogers , Mark Leather
IPC分类号： G06F15/16 , G06F15/00 , G06T1/00 , G06F9/48
CPC分类号： G06F9/4843
摘要： A method resumes an accelerated processing device (APD) wavefront in which a subset of elements have faulted. A restore command for a job including a wavefront is received. A list of context states for the wavefront is read from a memory associated with a APD. An empty shell wavefront is created for restoring the list of context states. A portion of not acknowledged data is masked over a portion of acknowledged data within the restored wavefronts.
摘要翻译：一种方法恢复加速处理设备（APD）波前，其中元素的子集已经发生故障。接收到包含波前的作业的恢复命令。从与APD相关联的存储器中读取波阵面的上下文状态列表。创建一个空壳波阵面用于恢复上下文状态列表。一部分未确认的数据被掩蔽在恢复的波前的一部分确认数据上。

5. 发明授权

US08933942B2 Partitioning resources of a processor 有权
标题翻译：分配处理器的资源
公开(公告)号：US08933942B2
公开(公告)日：2015-01-13
申请号：US13315121
申请日：2011-12-08
申请人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas Roy Woller , Kevin McGrath , Rex McCrary , Philip J. Rogers , Mark Leather
发明人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas Roy Woller , Kevin McGrath , Rex McCrary , Philip J. Rogers , Mark Leather
IPC分类号： G06F15/16 , G06T1/00 , G06F9/46 , G06F9/50
CPC分类号： G06F9/505 , G06F2209/509
摘要： Embodiments describe herein provide an apparatus, a computer readable medium and a method for simultaneously processing tasks within an APD. The method includes processing a first task within an APD. The method also includes reducing utilization of the APD by the first task to facilitate simultaneous processing of the second task, such that the utilization remains below a threshold.
摘要翻译：本文描述的实施例提供了一种用于同时处理APD内的任务的装置，计算机可读介质和方法。该方法包括处理APD内的第一任务。该方法还包括通过第一任务降低APD的利用率，以促进第二任务的同时处理，使得利用率保持低于阈值。

6. 发明授权

US08842539B2 Method of limiting the amount of network traffic reaching a local node operating according to an industrial ethernet protocol 有权
标题翻译：限制根据工业以太网协议到达本地节点运行的网络流量的方法
公开(公告)号：US08842539B2
公开(公告)日：2014-09-23
申请号：US13342459
申请日：2012-01-03
申请人： Kevin McGrath , Alexander Wold
发明人： Kevin McGrath , Alexander Wold
IPC分类号： H04L1/00 , H04L29/06 , H04L12/801 , H04L12/823
CPC分类号： H04L47/10 , H04L47/32 , H04L63/0227 , H04L63/101 , H04L63/162
摘要： A method of limiting the amount of network traffic reaching a local node in an electronic device operating an Ethernet networking protocol and using a network stack including at least one physical layer (PHY) and one link layer, preferably a media access controller (MAC). The electronic device is connected to a communication network, the network traffic is filtered, and an unwanted data reception is filtered out. Filtering the network traffic takes place during reception. Network traffic is inspected, and if an unwanted reception is detected, the unwanted data is discarded when it reaches media access controller (MAC) of the network stack of the electronic device. An electronic device, functioning as a node, embodying aspects of the invention is described, and a computer program for carrying out the invention is also described.
摘要翻译：一种限制在操作以太网网络协议的电子设备中到达本地节点的网络流量的量并且使用包括至少一个物理层（PHY）和一个链路层（优选媒体接入控制器（MAC））的网络栈的方法。电子设备连接到通信网络，网络流量被过滤，并且不期望的数据接收被过滤掉。过滤网络流量在接收过程中发生。检查网络流量，并且如果检测到不期望的接收，则当不期望的数据到达电子设备的网络堆栈的媒体访问控制器（MAC）时被丢弃。描述体现本发明的方面的用作节点的电子设备，并且还描述了用于实现本发明的计算机程序。

7. 发明申请

US20140022263A1 METHOD FOR URGENCY-BASED PREEMPTION OF A PROCESS 有权
标题翻译：用于基于紧急程序的过程的方法
公开(公告)号：US20140022263A1
公开(公告)日：2014-01-23
申请号：US13555866
申请日：2012-07-23
申请人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Kevin McGrath , Sebastien Nussbaum , Nuwan S. Jayasena , Rex Eldon McCrary , Mark Leather , Philip J. Rogers
发明人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Kevin McGrath , Sebastien Nussbaum , Nuwan S. Jayasena , Rex Eldon McCrary , Mark Leather , Philip J. Rogers
IPC分类号： G06T1/20
CPC分类号： G06T1/20 , G06F9/48 , G06F9/4881
摘要： The desire to use an Accelerated Processing Device (APD) for general computation has increased due to the APD's exemplary performance characteristics. However, current systems incur high overhead when dispatching work to the APD because a process cannot be efficiently identified or preempted. The occupying of the APD by a rogue process for arbitrary amounts of time can prevent the effective utilization of the available system capacity and can reduce the processing progress of the system. Embodiments described herein can overcome this deficiency by enabling the system software to pre-empt a process executing on the APD for any reason. The APD provides an interface for initiating such a pre-emption. This interface exposes an urgency of the request which determines whether the process being preempted is allowed a grace period to complete its issued work before being forced off the hardware.
摘要翻译：由于APD的示范性能特征，使用加速处理装置（APD）进行通用计算的愿望增加。然而，由于无法有效地识别或抢占过程，目前的系统在向APD发送作业时会产生高额的开销。通过流氓流程占用任意时间的APD可以防止有效利用现有的系统容量，并可以减少系统的处理进度。本文描述的实施例可以通过使得系统软件由于任何原因预先在APD上执行的过程来克服这个缺陷。 APD提供了一个用于启动此优先级的接口。该接口暴露了该请求的紧急性，该请求确定被抢占的进程是否被允许在宽限期之前完成其发出的工作，然后才被强制关闭硬件。

8. 发明申请

US20130147816A1 Partitioning Resources of a Processor 有权
标题翻译：处理器的分区资源
公开(公告)号：US20130147816A1
公开(公告)日：2013-06-13
申请号：US13315121
申请日：2011-12-08
申请人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas Woller , Kevin McGrath , Rex McCrary , Philip J. Rogers , Mark Leather
发明人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Thomas Woller , Kevin McGrath , Rex McCrary , Philip J. Rogers , Mark Leather
IPC分类号： G06F15/16 , G06T1/00
CPC分类号： G06F9/505 , G06F2209/509
摘要： Embodiments describe herein provide an apparatus, a computer readable medium and a method for simultaneously processing tasks within an APD. The method includes processing a first task within an APD. The method also includes reducing utilization of the APD by the first task to facilitate simultaneous processing of the second task, such that the utilization remains below a threshold.
摘要翻译：本文描述的实施例提供了一种用于同时处理APD内的任务的装置，计算机可读介质和方法。该方法包括处理APD内的第一任务。该方法还包括通过第一任务降低APD的利用率，以促进第二任务的同时处理，使得利用率保持低于阈值。

9. 发明申请

US20120200576A1 Preemptive context switching of processes on ac accelerated processing device (APD) based on time quanta 有权
标题翻译：基于时间量的交流加速处理设备（APD）上的进程的抢占上下文切换
公开(公告)号：US20120200576A1
公开(公告)日：2012-08-09
申请号：US13289809
申请日：2011-11-04
申请人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Kevin McGrath , Sebastien Nussbaum , Nuwan Jayasena , Rex McCrary , Mark Leather , Philip J. Rogers , Thomas Woller
发明人： Robert Scott Hartog , Ralph Clay Taylor , Michael Mantor , Kevin McGrath , Sebastien Nussbaum , Nuwan Jayasena , Rex McCrary , Mark Leather , Philip J. Rogers , Thomas Woller
IPC分类号： G06T1/00
CPC分类号： G06T1/20 , G06F9/4881 , G06F9/526 , G06T1/60
摘要： Methods, systems, and computer readable media for preemptive context-switching of processes on an accelerated processing device are based upon a comparison of the running time of the process and a threshold time quanta. A method includes preempting a process running on an accelerated processing device based upon a running time of the process and a threshold time quanta.
摘要翻译：用于加速处理设备上的进程的抢占上下文切换的方法，系统和计算机可读介质基于对进程的运行时间和阈值时间量子的比较。一种方法包括根据该过程的运行时间和一个阈值时间量子来抢占在加速处理设备上运行的进程。

10. 发明申请

US20070134747A1 Detection of secreted lipase proteins from Candida species 审中-公开
标题翻译：检测假丝酵母属分泌的脂肪酶蛋白
公开(公告)号：US20070134747A1
公开(公告)日：2007-06-14
申请号：US11302991
申请日：2005-12-14
申请人： Enrico DiGiammarino , Kevin McGrath
发明人： Enrico DiGiammarino , Kevin McGrath
IPC分类号： G01N33/53
CPC分类号： G01N33/573 , G01N2333/40 , G01N2333/918
摘要： Methods and devices for the detection of proteins secreted by the pathogenic growth form of Candida species are disclosed. The disclosed devices may constitute a method for the diagnosis of acute or chronic infections, including candidiasis, caused by microorganisms of the Candida species, such as C. albicans, for example. The devices of the present invention incorporate antibodies specific to lipase proteins whose expression is differentiated upon the conversion of the Candida species from the commensal to the pathogenic form. The antibodies may be used in assays to allow the diagnosis of candidal infections and disease conditions. Either monoclonal antibodies or polyclonal antibodies may be used, and in the case of the monoclonals, the specific epitopes of the LIP protein may be detected as well as the LIP protein itself.
摘要翻译：公开了用于检测由假丝酵母属病原体生长形式分泌的蛋白质的方法和装置。所公开的装置可以构成用于诊断例如由假丝酵母属物种的微生物引起的急性或慢性感染（包括念珠菌病）的方法，例如白色念珠菌。本发明的装置包含对脂肪酶蛋白特异性的抗体，其表达在将念珠菌属物种从共生转化为致病形式时是分化的。抗体可用于测定以允许诊断念珠菌感染和疾病状况。可以使用单克隆抗体或多克隆抗体，并且在单克隆抗体的情况下，可以检测LIP蛋白的特异性表位以及LIP蛋白本身。

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