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1. 发明授权

US08110112B2 Liquid to liquid biological particle concentrator 有权
标题翻译：液体至液体生物颗粒浓缩器
公开(公告)号：US08110112B2
公开(公告)日：2012-02-07
申请号：US12131015
申请日：2008-05-30
申请人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
发明人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
IPC分类号： B01D61/00 , B01D63/00 , B01D65/02
CPC分类号： C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
摘要： A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
摘要翻译：快速单程液体过滤系统有效地将悬浮在液体中的生物颗粒从稀释的进料悬浮液中浓缩。保留样品浓缩物或滞留物悬浮液，同时在单独的流动流中除去分离的流体。悬浮的生物颗粒包括尺寸范围为约0.001微米至20微米直径的蛋白质/毒素，病毒，DNA和/或细菌等材料。这些颗粒的浓度对于在稀释悬浮液中检测目标颗粒是有利的，因为将它们浓缩成小体积使得它们更易于检测。可以以“级联”方式添加额外的浓缩级，以便使浓缩样品悬浮液中残留在分离的流体中的每个先前阶段的尺寸切割下方的颗粒浓缩。该方法也可以用于产生在窄范围内浓缩特定靶尺寸颗粒的“带通”浓度。

2. 发明申请

US20140186819A1 Liquid to Liquid Biological Particle Concentrator 有权
标题翻译：液体至液体生物颗粒浓缩器
公开(公告)号：US20140186819A1
公开(公告)日：2014-07-03
申请号：US13368197
申请日：2012-02-07
申请人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
发明人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
IPC分类号： C12Q1/04
CPC分类号： C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
摘要： A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
摘要翻译：快速单程液体过滤系统有效地将悬浮在液体中的生物颗粒从稀释的进料悬浮液中浓缩。保留样品浓缩物或滞留物悬浮液，同时在单独的流动流中除去分离的流体。悬浮的生物颗粒包括尺寸范围为约0.001微米至20微米直径的蛋白质/毒素，病毒，DNA和/或细菌等材料。这些颗粒的浓度对于在稀释悬浮液中检测目标颗粒是有利的，因为将它们浓缩成小体积使得它们更易于检测。可以以“级联”方式添加额外的浓缩级，以便使浓缩样品悬浮液中残留在分离的流体中的每个先前阶段的尺寸切割下方的颗粒浓缩。该方法也可以用于产生在窄范围内浓缩特定靶尺寸颗粒的“带通”浓度。

3. 发明申请

US20090101575A1 Liquid To Liquid Biological Particle Concentrator 有权
标题翻译：液体到液体生物颗粒浓缩器
公开(公告)号：US20090101575A1
公开(公告)日：2009-04-23
申请号：US12131015
申请日：2008-05-30
申请人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
发明人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
IPC分类号： B01D65/06 , B01D29/66
CPC分类号： C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
摘要： A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
摘要翻译：快速单程液体过滤系统有效地将悬浮在液体中的生物颗粒从稀释的进料悬浮液中浓缩。保留样品浓缩物或滞留物悬浮液，同时在单独的流动流中除去分离的流体。悬浮的生物颗粒包括尺寸范围为约0.001微米至20微米直径的蛋白质/毒素，病毒，DNA和/或细菌等材料。这些颗粒的浓度对于在稀释悬浮液中检测目标颗粒是有利的，因为将它们浓缩成小体积使得它们更易于检测。可以以“级联”方式添加额外的浓缩级，以便使浓缩样品悬浮液中残留在分离的流体中的每个先前阶段的尺寸切割下方的颗粒浓缩。该方法也可以用于产生在窄范围内浓缩特定靶尺寸颗粒的“带通”浓度。

4. 发明授权

US08758623B1 Liquid to liquid biological particle concentrator 有权
标题翻译：液体至液体生物颗粒浓缩器
公开(公告)号：US08758623B1
公开(公告)日：2014-06-24
申请号：US13368197
申请日：2012-02-07
申请人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
发明人： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
IPC分类号： B01D65/02 , B01D11/00 , B01D24/00 , B01D63/00 , B08B9/00
CPC分类号： C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
摘要： A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
摘要翻译：快速单程液体过滤系统有效地将悬浮在液体中的生物颗粒从稀释的进料悬浮液中浓缩。保留样品浓缩物或滞留物悬浮液，同时在单独的流动流中除去分离的流体。悬浮的生物颗粒包括尺寸范围为约0.001微米至20微米直径的蛋白质/毒素，病毒，DNA和/或细菌等材料。这些颗粒的浓度对于在稀释悬浮液中检测目标颗粒是有利的，因为将它们浓缩成小体积使得它们更易于检测。可以以“级联”方式添加额外的浓缩级，以便使浓缩样品悬浮液中残留在分离的流体中的每个先前阶段的尺寸切割下方的颗粒浓缩。该方法也可以用于产生在窄范围内浓缩特定靶尺寸颗粒的“带通”浓度。

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