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1. 发明授权

US09510732B2 Methods and apparatus for efficient purging 有权
标题翻译：高效吹扫的方法和设备
公开(公告)号：US09510732B2
公开(公告)日：2016-12-06
申请号：US12499681
申请日：2009-07-08
申请人： David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh , Aseem K. Thakur , Chris A. Rothe , Edmund Tam
发明人： David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh , Aseem K. Thakur , Chris A. Rothe , Edmund Tam
IPC分类号： A61B1/00 , A61B1/04
CPC分类号： A61B1/126 , A61B1/0008 , A61B1/00082 , A61B1/00089 , A61B1/00165 , A61B1/051
摘要： Methods and apparatus for efficient purging from an imaging hood are described which facilitate the visualization of tissue regions through a clear fluid. Such a system may include an imaging hood having one or more layers covering the distal opening and defines one or more apertures which control the infusion and controlled retention of the clearing fluid into the hood. In this manner, the amount of clearing fluid may be limited and the clarity of the imaging of the underlying tissue through the fluid within the hood may be maintained for relatively longer periods of time by inhibiting, delaying, or preventing the infusion of surrounding blood into the viewing field. The aperture size may be controlled to decrease or increase through selective inflation of the membrane or other mechanisms.
摘要翻译：描述了用于从成像罩高效清洗的方法和装置，其通过透明流体促进组织区域的可视化。这样的系统可以包括具有覆盖远端开口的一层或多层的成像罩，并且限定一个或多个孔，其控制输液并将清除流体控制在罩中。以这种方式，可以限制清除液体的量，并且可以通过抑制，延迟或防止将周围血液输注到相对更长的时间段内，使通过罩内的流体的潜在组织的成像清晰度视野。可以通过膜或其它机构的选择性膨胀来控制孔径尺寸以减小或增加。

2. 发明授权

US09155587B2 Visual electrode ablation systems 有权
标题翻译：视觉电极消融系统
公开(公告)号：US09155587B2
公开(公告)日：2015-10-13
申请号：US12465903
申请日：2009-05-14
申请人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
发明人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
IPC分类号： A61B18/12 , A61B18/14 , A61B1/00 , A61B1/012 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B1/00089 , A61B1/012 , A61B2017/00106 , A61B2018/00214 , A61B2018/00577 , A61B2018/00642 , A61B2018/00809 , A61B2018/00839 , A61B2018/1472 , A61B2218/002
摘要： Visual electrode ablation systems are described herein which include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. An electric current may be passed through the fluid such that it passes directly to the tissue region being imaged and the electrical energy is conducted through the fluid without the need for a separate ablation probe or instrument to ablate the tissue being viewed.
摘要翻译：本文描述了视觉电极消融系统，其包括部署导管和可展开成扩展构型的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。电流可以通过流体，使得其直接通过被成像的组织区域，并且电能通过流体传导，而不需要单独的消融探针或器械来烧蚀被观察的组织。

3. 发明授权

US08709008B2 Visual electrode ablation systems 有权
标题翻译：视觉电极消融系统
公开(公告)号：US08709008B2
公开(公告)日：2014-04-29
申请号：US12118439
申请日：2008-05-09
申请人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
发明人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
IPC分类号： A61B18/12
CPC分类号： A61B18/1492 , A61B1/00089 , A61B1/012 , A61B2017/00106 , A61B2018/00214 , A61B2018/00577 , A61B2018/00642 , A61B2018/00809 , A61B2018/00839 , A61B2018/1472 , A61B2218/002
摘要： Visual electrode ablation systems are described herein which include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. An electric current may be passed through the fluid such that it passes directly to the tissue region being imaged and the electrical energy is conducted through the fluid without the need for a separate ablation probe or instrument to ablate the tissue being viewed.
摘要翻译：本文描述了视觉电极消融系统，其包括部署导管和可展开成扩展构型的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。电流可以通过流体，使得其直接通过被成像的组织区域，并且电能通过流体传导，而不需要单独的消融探针或器械来烧蚀被观察的组织。

4. 发明申请

US20090227999A1 VISUAL ELECTRODE ABLATION SYSTEMS 有权
标题翻译： VISUAL ELECTRODE ABLATION系统
公开(公告)号：US20090227999A1
公开(公告)日：2009-09-10
申请号：US12465903
申请日：2009-05-14
申请人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
发明人： N. Parker Willis , Zachary J. Malchano , Chris A. Rothe , Vahid Saadat , Ruey-Feng Peh , David Miller , Edmund Tam
IPC分类号： A61B18/14 , A61B18/20 , A61N7/00
CPC分类号： A61B18/1492 , A61B1/00089 , A61B1/012 , A61B2017/00106 , A61B2018/00214 , A61B2018/00577 , A61B2018/00642 , A61B2018/00809 , A61B2018/00839 , A61B2018/1472 , A61B2218/002
摘要： Visual electrode ablation systems are described herein which include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. An electric current may be passed through the fluid such that it passes directly to the tissue region being imaged and the electrical energy is conducted through the fluid without the need for a separate ablation probe or instrument to ablate the tissue being viewed.
摘要翻译：本文描述了视觉电极消融系统，其包括部署导管和可展开成扩展构型的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。电流可以通过流体，使得其直接通过被成像的组织区域，并且电能通过流体传导，而不需要单独的消融探针或器械来烧蚀被观察的组织。

5. 发明授权

US09101735B2 Catheter control systems 有权
标题翻译：导管控制系统
公开(公告)号：US09101735B2
公开(公告)日：2015-08-11
申请号：US12499011
申请日：2009-07-07
申请人： Chris A. Rothe , Juan Diego Perea , David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh
发明人： Chris A. Rothe , Juan Diego Perea , David Miller , Vahid Saadat , Zachary J. Malchano , Ruey-Feng Peh
IPC分类号： A61B1/01 , A61M25/01 , A61M25/00
CPC分类号： A61M25/0147 , A61M25/0074 , A61M25/0082 , A61M25/0105 , A61M25/0136 , A61M2025/015
摘要： Catheter control systems which facilitate the tracking of an angle of deflection of a catheter distal end can be used for any number of procedures where catheter orientation relative to the body is desirable, e.g., in transseptal access procedures where an accurate angle of puncture of the septal wall is desirable. Such control systems may comprise a steerable handle which is oriented relative to the catheter steerable section to provide for consistent catheter articulation upon corresponding manipulation of the steering ring. Another variation may utilize an orientation indicator to track the deflectable distal end. For instance, an orientation marker as visualized through an imaging hood on the distal end may correspond to identical orientation markers on the control handle such that articulation of a steering mechanism in a direction relative to the orientation markers deflects the catheter distal end in a corresponding direction relative to the visualized orientation markers.
摘要翻译：促进跟踪导管远端的偏转角度的导管控制系统可用于任何数量的程序，其中导管相对于身体的取向是期望的，例如在中间通道的准确的穿刺角度墙是理想的。这样的控制系统可以包括相对于导管可转向部分定向的可操纵手柄，以在相应操纵转向环时提供一致的导管关节运动。另一种变型可以利用取向指示器来跟踪可偏转的远端。例如，通过远端上的成像罩可视化的取向标记可以对应于控制手柄上的相同的取向标记，使得转向机构在相对于定向标记的方向上的关节转动导管远端在相应方向相对于可视化的取向标记。

6. 发明授权

US09155452B2 Complex shape steerable tissue visualization and manipulation catheter 有权
标题翻译：复杂形状可控组织可视化和操作导管
公开(公告)号：US09155452B2
公开(公告)日：2015-10-13
申请号：US12108812
申请日：2008-04-24
申请人： Chris A. Rothe , David Miller , Vahid Saadat , Ruey-Feng Peh , Edmund Tam
发明人： Chris A. Rothe , David Miller , Vahid Saadat , Ruey-Feng Peh , Edmund Tam
IPC分类号： A61B1/00 , A61M31/00 , A61M25/00 , A61B1/008 , A61B1/005 , A61B1/018 , A61B1/04 , A61B5/02 , A61M25/01
CPC分类号： A61B1/01 , A61B1/00006 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/00096 , A61B1/00154 , A61B1/0051 , A61B1/0057 , A61B1/008 , A61B1/015 , A61B1/018 , A61B1/042 , A61B1/05 , A61B1/06 , A61B5/02007 , A61B18/1492 , A61B2018/00577 , A61M25/0138 , A61M25/0147 , A61M2025/0161
摘要： Complex shape steerable tissue visualization and manipulation catheters and their methods of use of disclosed herein. The deployment catheter may be articulated utilizing various steering mechanisms to adjust a position of a visualization hood or membrane through which underlying tissue may be visualized.
摘要翻译：复合形状可操纵的组织可视化和操作导管及其本文公开的使用方法。可以使用各种转向机构来铰接展开导管，以调整可视化罩或膜的位置，通过该位置可以将潜在的组织可视化。

7. 发明授权

US08417321B2 Flow reduction hood systems 有权
标题翻译：减流罩系统
公开(公告)号：US08417321B2
公开(公告)日：2013-04-09
申请号：US13216683
申请日：2011-08-24
申请人： Vahid Saadat , Edmund Tam , Chris A. Rothe , David Miller , Ruey-Feng Peh
发明人： Vahid Saadat , Edmund Tam , Chris A. Rothe , David Miller , Ruey-Feng Peh
IPC分类号： A61B6/00
CPC分类号： A61B1/00089 , A61B1/0008 , A61B1/00147 , A61B1/00165 , A61B1/015 , A61B1/018 , A61B1/05 , A61B1/051 , A61B1/12 , A61B1/3137 , A61B1/32 , A61B5/6851 , A61B6/503 , A61B17/29 , A61B18/00 , A61B18/18
摘要： Flow reduction hood systems are described which facilitate the visualization of tissue regions through a clear fluid. Such a system may include an imaging hood having one or more layers covering the distal opening and defines one or more apertures which control the infusion and controlled retention of the clearing fluid into the hood. In this manner, the amount of clearing fluid may be limited and the clarity of the imaging of the underlying tissue through the fluid within the hood may be maintained for relatively longer periods of time by inhibiting, delaying, or preventing the infusion of surrounding blood into the viewing field. The aperture size may be controlled to decrease or increase through selective inflation of the membrane or other mechanisms.
摘要翻译：描述了减少排气罩系统，其通过透明流体促进组织区域的可视化。这样的系统可以包括具有覆盖远端开口的一层或多层的成像罩，并且限定一个或多个孔，其控制输液并将清除流体控制在罩中。以这种方式，可以限制清除液体的量，并且可以通过抑制，延迟或防止将周围血液输注到相对更长的时间段内，使通过罩内的流体的潜在组织的成像清晰度视野。可以通过膜或其它机构的选择性膨胀来控制孔径尺寸以减小或增加。

8. 发明授权

US08078266B2 Flow reduction hood systems 有权
标题翻译：减流罩系统
公开(公告)号：US08078266B2
公开(公告)日：2011-12-13
申请号：US12026455
申请日：2008-02-05
申请人： Vahid Saadat , Edmund Tam , Chris A. Rothe , David Miller , Ruey-Feng Peh
发明人： Vahid Saadat , Edmund Tam , Chris A. Rothe , David Miller , Ruey-Feng Peh
IPC分类号： A61B6/00
CPC分类号： A61B1/00089 , A61B1/0008 , A61B1/00147 , A61B1/00165 , A61B1/015 , A61B1/018 , A61B1/05 , A61B1/051 , A61B1/12 , A61B1/3137 , A61B1/32 , A61B5/6851 , A61B6/503 , A61B17/29 , A61B18/00 , A61B18/18
摘要： Flow reduction hood systems are described which facilitate the visualization of tissue regions through a clear fluid. Such a system may include an imaging hood having one or more layers covering the distal opening and defines one or more apertures which control the infusion and controlled retention of the clearing fluid into the hood. In this manner, the amount of clearing fluid may be limited and the clarity of the imaging of the underlying tissue through the fluid within the hood may be maintained for relatively longer periods of time by inhibiting, delaying, or preventing the infusion of surrounding blood into the viewing field. The aperture size may be controlled to decrease or increase through selective inflation of the membrane or other mechanisms.
摘要翻译：描述了减少排气罩系统，其通过透明流体促进组织区域的可视化。这样的系统可以包括具有覆盖远端开口的一层或多层的成像罩，并且限定一个或多个孔，其控制输液并将清除流体控制在罩中。以这种方式，可以限制清除液体的量，并且可以通过抑制，延迟或防止将周围血液输注到相对更长的时间段内，使通过罩内的流体的潜在组织的成像清晰度视野。可以通过膜或其它机构的选择性膨胀来控制孔径尺寸以减小或增加。

9. 发明授权

US08235985B2 Visualization and ablation system variations 有权
标题翻译：可视化和消融系统的变化
公开(公告)号：US08235985B2
公开(公告)日：2012-08-07
申请号：US12209057
申请日：2008-09-11
申请人： Vahid Saadat , Ruey-Feng Peh , Zachary J. Malchano , Chris A. Rothe
发明人： Vahid Saadat , Ruey-Feng Peh , Zachary J. Malchano , Chris A. Rothe
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B1/00165 , A61B18/1477 , A61B90/37 , A61B2018/00214 , A61B2018/00285 , A61B2018/00351 , A61B2018/00577 , A61B2018/00898 , A61B2018/1425 , A61B2218/002
摘要： Visualization and ablation system variations are described which utilize various tissue ablation arrangements. Such assemblies are configured to facilitate the application of bipolar energy delivery, such as RF ablation, to an underlying target tissue for treatment in a controlled manner while directly visualizing the tissue during the bipolar ablation process.
摘要翻译：描述了利用各种组织消融装置的可视化和消融系统变化。这种组件被配置为便于将双极能量输送（例如RF消融）应用于潜在的靶组织，以受控的方式进行治疗，同时在双极烧蚀过程期间直接使组织可视化。

10. 发明授权

US08333012B2 Method of forming electrode placement and connection systems 有权
标题翻译：形成电极放置和连接系统的方法
公开(公告)号：US08333012B2
公开(公告)日：2012-12-18
申请号：US12575674
申请日：2009-10-08
申请人： Chris A. Rothe , Isidro M. Gandionco , Edmund Tam , Vahid Saadat , David Miller , Zachary J. Malchano , Veerappan Swaminathan
发明人： Chris A. Rothe , Isidro M. Gandionco , Edmund Tam , Vahid Saadat , David Miller , Zachary J. Malchano , Veerappan Swaminathan
IPC分类号： H01R43/00
CPC分类号： A61B1/018 , A61B1/0008 , A61B1/00087 , A61B1/00089 , A61B1/05 , A61B1/3137 , A61N1/05 , Y10T29/49117 , Y10T29/49124 , Y10T29/49155 , Y10T29/49222
摘要： Electrode placement and connection systems are described which allow for the electrical connection and maintenance of one or more electrodes positioned on a substrate which is subjected to a variety of mechanical stresses. Such a system may include an imaging hood having an aperture through which transparent fluid is flowed and one or more electrodes positioned along or about the hood. As the hood is configured between a low-profile and opened configuration, these electrodes may remain electrically coupled despite the mechanical stresses subjected to the electrodes and the connections thereto.
摘要翻译：描述了电极放置和连接系统，其允许位于经受各种机械应力的基板上的一个或多个电极的电连接和维护。这样的系统可以包括具有孔的成像罩，透明液体通过所述孔流动，并且一个或多个电极沿着或围绕罩定位。由于罩被配置在低轮廓和打开的构型之间，尽管机械应力受到电极及其连接，但是这些电极可以保持电耦合。

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