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1. 发明申请

US20130101079A1 Method For Controlling Radiation Dose and Intravenous Contrast Dose In Computed Tomography Imaging 有权
标题翻译：在计算机断层扫描成像中控制辐射剂量和静脉内对比剂量的方法
公开(公告)号：US20130101079A1
公开(公告)日：2013-04-25
申请号：US13654496
申请日：2012-10-18
申请人： David M. Hough , Lifeng Yu , Joel G. Fletcher , Cynthia H. McCollough
发明人： David M. Hough , Lifeng Yu , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/032 , A61B6/481 , A61B6/488 , A61B6/544 , A61B6/545
摘要： A system and method for acquiring an image of a region of interest (ROI) of subject using a computed tomography (CT) system includes a) performing a scout scan of the subject using the CT system to yield scout data related to the ROI and b) determining an initial contrast volume form at least the scout data. The method also includes c) prescribing a scanning protocol to be implemented using the computed tomography system to image the ROI and d) determining a size of the subject about the ROI. The method further includes e) determining a computed tomography dose related to volume (CTDIvol) based on at least the size determined at step d) and f) adjusting the scanning protocol prescribed in step b) to match at least one of a desired radiation dose and a relative intravenous (IV) contrast dose to a reference CTDIvol. The method includes g) acquiring imaging data from the ROI using the CT system by using the adjusted scanning protocol.
摘要翻译：使用计算机断层摄影（CT）系统获取被摄体区域的图像的系统和方法包括：a）使用CT系统执行对象的侦察扫描以产生与ROI和b相关的侦察数据）确定至少所述侦察数据的初始对比度体积。该方法还包括c）规定使用计算机断层摄影系统实现的扫描协议以对ROI进行成像，以及d）确定关于ROI的对象的大小。所述方法还包括：e）至少基于在步骤d）确定的尺寸来确定与体积（CTDIvol）有关的计算机断层摄影剂量，以及f）调整步骤b）中规定的扫描方案以使所需辐射剂量和相对静脉注射（IV）对照剂量与参考CTDIvol。该方法包括：g）通过使用经调整的扫描方案，使用CT系统从ROI获取成像数据。

2. 发明授权

US09173617B2 Method for controlling radiation dose and intravenous contrast dose in computed tomography imaging 有权
标题翻译：计算机断层成像中控制辐射剂量和静脉注射剂量的方法
公开(公告)号：US09173617B2
公开(公告)日：2015-11-03
申请号：US13654496
申请日：2012-10-18
申请人： David M. Hough , Lifeng Yu , Joel G. Fletcher , Cynthia H. McCollough
发明人： David M. Hough , Lifeng Yu , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/03 , A61B6/032 , A61B6/481 , A61B6/488 , A61B6/544 , A61B6/545
摘要： A system and method for acquiring an image of a region of interest (ROI) of subject using a computed tomography (CT) system includes a) performing a scout scan of the subject using the CT system to yield scout data related to the ROI and b) determining an initial contrast volume form at least the scout data. The method also includes c) prescribing a scanning protocol to be implemented using the computed tomography system to image the ROI and d) determining a size of the subject about the ROI. The method further includes e) determining a computed tomography dose related to volume (CTDIvol) based on at least the size determined at step d) and f) adjusting the scanning protocol prescribed in step b) to match at least one of a desired radiation dose and a relative intravenous (IV) contrast dose to a reference CTDIvol. The method includes g) acquiring imaging data from the ROI using the CT system by using the adjusted scanning protocol.
摘要翻译：使用计算机断层摄影（CT）系统获取被摄体区域的图像的系统和方法包括：a）使用CT系统执行对象的侦察扫描以产生与ROI和b相关的侦察数据）确定至少所述侦察数据的初始对比度体积。该方法还包括c）规定使用计算机断层摄影系统实现的扫描协议以对ROI进行成像，以及d）确定关于ROI的对象的大小。所述方法还包括：e）至少基于在步骤d）确定的尺寸来确定与体积（CTDIvol）有关的计算机断层摄影剂量，以及f）调整步骤b）中规定的扫描方案以使所需辐射剂量和相对静脉注射（IV）对照剂量与参考CTDIvol。该方法包括：g）通过使用经调整的扫描方案，使用CT系统从ROI获取成像数据。

3. 发明申请

US20140177784A1 System and Method for Automatic Tube Potential Selection for Dose Reduction in Medical Imaging 有权
标题翻译：自动管电位选择用于医学成像降低剂量的系统和方法
公开(公告)号：US20140177784A1
公开(公告)日：2014-06-26
申请号：US14183639
申请日：2014-02-19
申请人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.
摘要翻译：一种用于CT成像的方法，其利用针对个体对象和诊断任务的自动管电位选择。该方法量化不同管电位的相对辐射剂量以实现特定的图像质量。这允许选择提供减小的辐射剂量的管电位，同时仍然提供足够质量的CT图像。

4. 发明授权

US08903037B2 System and method for automatic tube potential selection for dose reduction in medical imaging 有权
公开(公告)号：US08903037B2
公开(公告)日：2014-12-02
申请号：US14183639
申请日：2014-02-19
申请人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
IPC分类号： A61B6/03 , A61B6/00
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.

5. 发明授权

US08699658B2 System and method for automatic tube potential selection for dose reduction in medical imaging 有权
标题翻译：用于医学成像剂量减少的自动管电位选择的系统和方法
公开(公告)号：US08699658B2
公开(公告)日：2014-04-15
申请号：US13384454
申请日：2010-07-15
申请人： Lifeng Yu , Cynthia H McCollough , Joel G Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H McCollough , Joel G Fletcher , Hua Li
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.
摘要翻译：一种用于CT成像的方法，其利用针对个体对象和诊断任务的自动管电位选择。该方法量化不同管电位的相对辐射剂量以实现特定的图像质量。这允许选择提供减小的辐射剂量的管电位，同时仍然提供足够质量的CT图像。

6. 发明申请

US20130202080A1 System and Method for Denoising Medical Images Adaptive to Local Noise 有权
标题翻译：用于去噪局部噪声的医学图像的系统和方法
公开(公告)号：US20130202080A1
公开(公告)日：2013-08-08
申请号：US13762141
申请日：2013-02-07
申请人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
发明人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： G06T11/003 , A61B6/032 , A61B6/5205 , A61B6/5258 , A61B6/542 , A61B6/583
摘要： A system and method is provided for estimating the local noise of CT images and denoising the images using a modified non-local means (NLM) algorithm that is adaptive to local variations of noise levels. A strategy for efficiently estimating the local noise of CT images is also described.
摘要翻译：提供了一种用于估计CT图像的局部噪声并使用适应于噪声水平的局部变化的修改的非局部平均（NLM）算法去噪图像的系统和方法。还描述了用于有效估计CT图像的局部噪声的策略。

7. 发明申请

US20120114093A1 System and Method for Automatic Tube Potential Selection for Dose Reduction in Medical Imaging 有权
标题翻译：自动管电位选择用于医学成像降低剂量的系统和方法
公开(公告)号：US20120114093A1
公开(公告)日：2012-05-10
申请号：US13384454
申请日：2010-07-15
申请人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
发明人： Lifeng Yu , Cynthia H. McCollough , Joel G. Fletcher , Hua Li
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/032 , A61B6/405 , A61B6/481 , A61B6/504 , A61B6/542 , A61B6/544 , A61B6/545
摘要： A method for CT imaging that utilizes an automatic tube potential selection for individual subjects and diagnostic tasks. The method quantifies the relative radiation dose of different tube potentials for achieving a specific image quality. This allows the selection of a tube potential that provides a reduced radiation dose while still providing CT images of a sufficient quality.
摘要翻译：一种用于CT成像的方法，其利用针对个体对象和诊断任务的自动管电位选择。该方法量化不同管电位的相对辐射剂量以实现特定的图像质量。这允许选择提供减小的辐射剂量的管电位，同时仍然提供足够质量的CT图像。

8. 发明授权

US09208585B2 System and method for improved energy series of images using multi-energy CT 有权
标题翻译：使用多能量CT改进能量系列图像的系统和方法
公开(公告)号：US09208585B2
公开(公告)日：2015-12-08
申请号：US13809800
申请日：2011-07-18
申请人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
发明人： Shuai Leng , Cynthia H. McCollough , Lifeng Yu , Joel G. Fletcher , Charles A. Mistretta
IPC分类号： G06T11/00 , A61B6/03 , A61B6/00 , G01N23/04
CPC分类号： G06T11/003 , A61B6/032 , A61B6/4241 , A61B6/482 , A61B6/50 , A61B6/5205 , G01N23/046 , G01N2223/1016 , G01N2223/419 , G01N2223/423 , G06T5/20
摘要： A method for creating an energy series of images acquired using a multi-energy computed tomography (CT) imaging system having a plurality of energy bins includes acquiring, with the multi-energy CT imaging system, a series of energy data sets, where each energy data set is associated with at least one of the energy bins. The method includes producing a conglomerate image using at least a plurality of the energy data sets and, using the conglomerate image, reconstructing an energy series of images, each image in the energy series of images corresponding to at least one of the energy data sets.
摘要翻译：一种用于创建使用具有多个能量箱的多能量计算机断层摄影（CT）成像系统获取的能量系列图像的方法包括采用多能CT成像系统获取一系列能量数据集，其中每个能量数据集与至少一个能量箱相关联。该方法包括使用至少多个能量数据集生成聚集图像，并且使用该聚集图像重建能量系列的图像，能量系列图像中的每个图像对应于能量数据集中的至少一个。

9. 发明授权

US09036771B2 System and method for denoising medical images adaptive to local noise 有权
标题翻译：用于去噪适应局部噪声的医学图像的系统和方法
公开(公告)号：US09036771B2
公开(公告)日：2015-05-19
申请号：US13762141
申请日：2013-02-07
申请人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
发明人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： A61B6/00 , G06T11/00 , A61B6/03
CPC分类号： G06T11/003 , A61B6/032 , A61B6/5205 , A61B6/5258 , A61B6/542 , A61B6/583
摘要： A system and method is provided for estimating the local noise of CT images and denoising the images using a modified non-local means (NLM) algorithm that is adaptive to local variations of noise levels. A strategy for efficiently estimating the local noise of CT images is also described.
摘要翻译：提供了一种用于估计CT图像的局部噪声并使用适应于噪声水平的局部变化的修改的非局部平均（NLM）算法去噪图像的系统和方法。还描述了用于有效估计CT图像的局部噪声的策略。

10. 发明申请

US20130202079A1 System and Method for Controlling Radiation Dose for Radiological Applications 审中-公开
标题翻译：用于放射应用辐射剂量控制的系统和方法
公开(公告)号：US20130202079A1
公开(公告)日：2013-08-08
申请号：US13751555
申请日：2013-01-28
申请人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
发明人： Lifeng Yu , Armando Manduca , Zhoubo Li , Joel G. Fletcher , Cynthia H. McCollough
IPC分类号： G06T11/00 , A61B6/03
CPC分类号： G06T11/003 , A61B6/032 , A61B6/5205 , A61B6/5258 , A61B6/542 , A61B6/583
摘要： A system and method for reconstructing an image acquired by delivering an irradiating dose of radiation to a subject includes acquiring imaging data using a dose of irradiating radiation and selecting at least one of a plurality of mechanisms for reducing the dose that could be delivered to the subject to acquire additional imaging data. Noise is inserted into the imaging data to simulate the at least one of the plurality of mechanisms for reducing the dose that could be applied to acquire the additional imaging data to thereby generate simulated imaging data at a reduced dose of irradiating radiation. A simulated reduced dose image is reconstructed from the simulated imaging data. A method is provided for utilizing a non-local means filter adapted using a map of local noise to produce denoised medical imaging data reflecting reduced local nose levels from those in originally-acquired medical imaging data.
摘要翻译：用于重建通过将照射剂量的辐射递送到对象而获取的图像的系统和方法包括使用照射辐射的剂量获取成像数据，并且选择用于减少可递送给受试者的剂量的多个机制中的至少一个以获取附加的成像数据。将噪声插入到成像数据中以模拟多个机构中的至少一个，用于减少可以用于获取附加成像数据的剂量，从而以减少的照射辐射剂量生成模拟成像数据。从模拟成像数据重建模拟的降低剂量图像。提供了一种利用适合使用局部噪声图的非局部均值滤波器的方法来产生反映本地鼻部水平的降噪的医学成像数据与本来获取的医学成像数据中的那些。

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