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1. 发明申请

US20140172087A1 METHOD FOR PHYSIOLOGIC CONTROL OF A CONTINUOUS FLOW TOTAL ARTIFICIAL HEART 有权
标题翻译：连续流量人造心脏生理控制方法
公开(公告)号：US20140172087A1
公开(公告)日：2014-06-19
申请号：US14187615
申请日：2014-02-24
申请人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
发明人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
IPC分类号： A61M1/10 , F04D15/00
CPC分类号： A61M1/1001 , A61M1/1005 , A61M1/101 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M2205/3334 , F04D15/0066
摘要： A method is provided of controlling a pump including a electrical motor coupled to a rotor which carries first and second impellers at opposite ends thereof. The method includes: (a) driving the rotor using the motor, so as to circulate fluid from the first impeller through a first fluid circuit, the second impeller, a second fluid circuit, and back to the first impeller; (b) determining a resistance of the first fluid circuit, based on a first motor parameter which is a function of electrical power delivered to the motor; (c) determining a flow rate through the first fluid circuit based on a second motor parameter which is a function of electrical power delivered to the motor; and (d) varying at least one operational parameter of the pump so as to maintain a predetermined relationship between the flow rate and the resistance of the first fluid circuit.
摘要翻译：提供了一种控制泵的方法，该泵包括耦合到转子的电动机，该转子在其相对端承载第一和第二叶轮。该方法包括：（a）使用电动机驱动转子，以使来自第一叶轮的流体通过第一流体回路，第二叶轮，第二流体回路循环到第一叶轮; （b）基于作为传送到电动机的电功率的函数的第一电动机参数来确定第一流体回路的电阻; （c）基于作为传送到所述电动机的电功率的函数的第二电动机参数来确定通过所述第一流体回路的流量; 以及（d）改变所述泵的至少一个操作参数，以便保持所述第一流体回路的流量和所述阻力之间的预定关系。

2. 发明授权

US08657874B2 Method for physiologic control of a continuous flow total artificial heart 有权
标题翻译：连续流总人造心脏生理控制方法
公开(公告)号：US08657874B2
公开(公告)日：2014-02-25
申请号：US12349658
申请日：2009-01-07
申请人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
发明人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
IPC分类号： A61M1/10
CPC分类号： A61M1/1001 , A61M1/1005 , A61M1/101 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M2205/3334 , F04D15/0066
摘要： A method is provided of controlling a pump including a electrical motor coupled to a rotor which carries first and second impellers at opposite ends thereof. The method includes: (a) driving the rotor using the motor, so as to circulate fluid from the first impeller through a first fluid circuit, the second impeller, a second fluid circuit, and back to the first impeller; (b) determining a resistance of the first fluid circuit, based on a first motor parameter; (c) determining a flow rate through the first fluid circuit based on a second motor parameter; and (d) varying at least one operational parameter of the pump so as to maintain a predetermined relationship between the flow rate and the resistance of the first fluid circuit.
摘要翻译：提供了一种控制泵的方法，该泵包括耦合到转子的电动机，该转子在其相对端承载第一和第二叶轮。该方法包括：（a）使用电动机驱动转子，以使来自第一叶轮的流体通过第一流体回路，第二叶轮，第二流体回路循环到第一叶轮; （b）基于第一电动机参数确定第一流体回路的电阻; （c）基于第二电动机参数确定通过第一流体回路的流量; 以及（d）改变所述泵的至少一个操作参数，以便保持所述第一流体回路的流量和所述阻力之间的预定关系。

3. 发明授权

US09162019B2 Two-stage rotodynamic blood pump 有权
标题翻译：两级旋转动力血泵
公开(公告)号：US09162019B2
公开(公告)日：2015-10-20
申请号：US13540037
申请日：2012-07-02
申请人： David Horvath , Leonard A. R. Golding , Alex Massiello , Barry Kuban
发明人： David Horvath , Leonard A. R. Golding , Alex Massiello , Barry Kuban
IPC分类号： A61M1/10 , F04D1/06 , F04D13/06 , F04D13/14 , F04D15/00 , A61M1/12
CPC分类号： A61M1/1031 , A61M1/1005 , A61M1/101 , A61M1/1013 , A61M1/1015 , A61M1/1017 , A61M1/1029 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , F04D1/06 , F04D13/06 , F04D13/064 , F04D13/14 , F04D15/0033
摘要： A pump includes a housing, a stator supported in the housing, and a rotor assembly including a rotor supported in the housing for rotation relative to the stator about an axis. The stator includes a stator core, a first lamination wound around an axial portion of the stator core, and a second lamination wound around a second axial portion of the stator core. The first and second laminations are spaced from each other along the length of the stator core. The rotor includes a rotor core, a first magnet assembly that extends around an axial portion of the rotor core, and a second magnet assembly that extends around a second axial portion of the rotor core. The first and second magnet assemblies are spaced from each other along the length of the rotor.
摘要翻译：泵包括壳体，支撑在壳体中的定子，以及转子组件，其包括支撑在壳体中的转子，用于相对于定子围绕轴线旋转。定子包括定子芯，围绕定子芯的轴向部分缠绕的第一层叠体，以及缠绕在定子芯的第二轴向部分上的第二层压体。第一和第二叠片沿着定子芯的长度彼此间隔开。转子包括转子芯，围绕转子芯的轴向部分延伸的第一磁体组件和围绕转子芯的第二轴向部分延伸的第二磁体组件。第一和第二磁体组件沿着转子的长度彼此间隔开。

4. 发明授权

US09821098B2 Method for physiologic control of a continuous flow total artificial heart 有权
公开(公告)号：US09821098B2
公开(公告)日：2017-11-21
申请号：US14187615
申请日：2014-02-24
申请人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
发明人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
IPC分类号： A61M1/10 , F04D15/00 , A61M1/12
CPC分类号： A61M1/1001 , A61M1/1005 , A61M1/101 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M2205/3334 , F04D15/0066
摘要： A method is provided of controlling a pump including a electrical motor coupled to a rotor which carries first and second impellers at opposite ends thereof. The method includes: (a) driving the rotor using the motor, so as to circulate fluid from the first impeller through a first fluid circuit, the second impeller, a second fluid circuit, and back to the first impeller; (b) determining a resistance of the first fluid circuit, based on a first motor parameter which is a function of electrical power delivered to the motor; (c) determining a flow rate through the first fluid circuit based on a second motor parameter which is a function of electrical power delivered to the motor; and (d) varying at least one operational parameter of the pump so as to maintain a predetermined relationship between the flow rate and the resistance of the first fluid circuit.

5. 发明申请

US20100174231A1 METHOD FOR PHYSIOLOGIC CONTROL OF A CONTINUOUS FLOW TOTAL ARTIFICIAL HEART 有权
标题翻译：连续流量人造心脏生理控制方法
公开(公告)号：US20100174231A1
公开(公告)日：2010-07-08
申请号：US12349658
申请日：2009-01-07
申请人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
发明人： David Horvath , Alex Massiello , Leonard A. R. Golding , Barry Kuban
IPC分类号： A61M31/00
CPC分类号： A61M1/1001 , A61M1/1005 , A61M1/101 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M2205/3334 , F04D15/0066
摘要： A method is provided of controlling a pump including a electrical motor coupled to a rotor which carries first and second impellers at opposite ends thereof. The method includes: (a) driving the rotor using the motor, so as to circulate fluid from the first impeller through a first fluid circuit, the second impeller, a second fluid circuit, and back to the first impeller; (b) determining a resistance of the first fluid circuit, based on a first motor parameter; (c) determining a flow rate through the first fluid circuit based on a second motor parameter; and (d) varying at least one operational parameter of the pump so as to maintain a predetermined relationship between the flow rate and the resistance of the first fluid circuit.
摘要翻译：提供了一种控制泵的方法，该泵包括耦合到转子的电动机，该转子在其相对端承载第一和第二叶轮。该方法包括：（a）使用电动机驱动转子，以使来自第一叶轮的流体通过第一流体回路，第二叶轮，第二流体回路循环到第一叶轮; （b）基于第一电动机参数确定第一流体回路的电阻; （c）基于第二电动机参数确定通过第一流体回路的流量; 以及（d）改变所述泵的至少一个操作参数，以便保持所述第一流体回路的流量和所述阻力之间的预定关系。

6. 发明授权

US08210829B2 Two-stage rotodynamic blood pump with axially movable rotor assembly for adjusting hydraulic performance characteristics 有权
标题翻译：具有轴向移动转子组件的两级旋转动力血泵用于调节液压性能特征
公开(公告)号：US08210829B2
公开(公告)日：2012-07-03
申请号：US12720953
申请日：2010-03-10
申请人： David Horvath , Leonard A. R. Golding , Alex Massiello
发明人： David Horvath , Leonard A. R. Golding , Alex Massiello
IPC分类号： F04D27/00 , F04D29/042 , F04D29/40 , A61M1/10
CPC分类号： F04D13/0633 , A61M1/1005 , A61M1/101 , A61M1/1013 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/3334 , F04D1/06 , F04D13/06 , F04D13/064 , F04D13/14 , F04D15/0033 , F04D29/042
摘要： A pump (10) includes a housing, a stator (20) supported in the housing, and a rotor assembly (30). The rotor assembly (30) includes a rotor (32) supported in the housing for rotation relative to the stator (20) about an axis (12). The rotor assembly (30) also includes a first impeller (34) operatively coupled to a first axial end of the rotor (32) for rotation with the rotor about the axis (12). The rotor assembly further includes a second impeller (36) operatively coupled to a second axial end of the rotor (32), opposite the first axial end, for rotation with the rotor about the axis (12). The rotor assembly (30) is movable along the axis (12) relative to the housing to adjust hydraulic performance characteristics of the pump (10).
摘要翻译：泵（10）包括壳体，支撑在壳体中的定子（20）和转子组件（30）。转子组件（30）包括支撑在壳体中以绕轴线（12）相对于定子（20）旋转的转子（32）。转子组件（30）还包括可操作地联接到转子（32）的第一轴向端部的第一叶轮（34），用于使转子围绕轴线（12）旋转。转子组件还包括可操作地联接到转子（32）的与第一轴向端相对的第二轴向端的第二叶轮（36），用于使转子绕轴线（12）旋转。转子组件（30）可相对于壳体沿着轴线（12）移动，以调节泵（10）的液压性能特性。

7. 发明授权

US07704054B2 Two-stage rotodynamic blood pump 有权
标题翻译：两级旋转动力血泵
公开(公告)号：US07704054B2
公开(公告)日：2010-04-27
申请号：US11789205
申请日：2007-04-24
申请人： David Horvath , Leonard A. R. Golding , Alex Massiello
发明人： David Horvath , Leonard A. R. Golding , Alex Massiello
IPC分类号： F04B49/00 , F03B3/12 , F04B17/04 , A61M1/10
CPC分类号： F04D1/06 , A61M1/1005 , A61M1/101 , A61M1/1013 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/3334 , F04D13/0633 , F04D13/064 , F04D29/042
摘要： A pump (10) includes a housing, a stator (20) supported in the housing, and a rotor assembly (30). The rotor assembly (30) includes a rotor (32) supported in the housing for rotation relative to the stator (20) about an axis (12). The rotor assembly (30) also includes a first impeller (34) operatively coupled to a first axial end of the rotor (32) for rotation with the rotor about the axis (12). The rotor assembly further includes a second impeller (36) operatively coupled to a second axial end of the rotor (32), opposite the first axial end, for rotation with the rotor about the axis (12). The rotor assembly (30) is movable along the axis (12) relative to the housing to adjust hydraulic performance characteristics of the pump (10).
摘要翻译：泵（10）包括壳体，支撑在壳体中的定子（20）和转子组件（30）。转子组件（30）包括支撑在壳体中以绕轴线（12）相对于定子（20）旋转的转子（32）。转子组件（30）还包括可操作地联接到转子（32）的第一轴向端部的第一叶轮（34），用于使转子围绕轴线（12）旋转。转子组件还包括可操作地联接到转子（32）的与第一轴向端相对的第二轴向端的第二叶轮（36），用于使转子绕轴线（12）旋转。转子组件（30）可相对于壳体沿着轴线（12）移动，以调节泵（10）的液压性能特性。

8. 发明授权

US07189260B2 Ventricular assist system secondary impeller 有权
标题翻译：心室辅助系统二级叶轮
公开(公告)号：US07189260B2
公开(公告)日：2007-03-13
申请号：US10333760
申请日：2001-03-19
申请人： David Horvath , Leonard A. R. Golding , William A. Smith
发明人： David Horvath , Leonard A. R. Golding , William A. Smith
IPC分类号： A61M1/10
CPC分类号： F04D29/2211 , A61M1/101 , A61M1/1012 , A61M1/1017 , A61M1/1031 , A61M1/122 , A61M1/127 , F04D13/0646
摘要： In a centrifugal flow blood pump, usable in left ventricular assist applications, blood is pumped from an inlet (16) to an outlet (22) by a primary impeller (18). A portion of the blood that enters the pump follows a secondary channel (24) where a secondary impeller (70) routes the blood to lubricate a bearing between an impeller assembly (14) and a post formed by a component of the pump housing. The unique shape of the secondary impeller (70) prevents blood stagnation and provides for a well-washed fluid bearing.
摘要翻译：在可用于左心室辅助应用的离心流血泵中，血液通过主叶轮（18）从入口（16）泵送到出口（22）。进入泵的一部分血液遵循辅助通道（24），其中次级叶轮（70）引导血液以润滑叶轮组件（14）和由泵壳体的部件形成的柱之间的轴承。二次叶轮（70）的独特形状防止血液滞留，并提供良好洗涤的流体轴承。

9. 发明授权

US07645225B2 Chronic performance control system for rotodynamic blood pumps 有权
标题翻译：用于旋转动力血泵的慢性性能控制系统
公开(公告)号：US07645225B2
公开(公告)日：2010-01-12
申请号：US10333759
申请日：2001-03-19
申请人： Alexander Medvedev , Leonard A. R. Golding , Alexander Massiello
发明人： Alexander Medvedev , Leonard A. R. Golding , Alexander Massiello
IPC分类号： A61M1/12
CPC分类号： A61M1/101 , A61M1/1086 , A61M1/122 , A61M2205/3334 , A61M2205/3365
摘要： In a left ventricular assist device (LVAD) a rotodynamic blood pump (10) is powered by a brushless DC motor (12). A power supply (14) supplies power to the motor (12). Three feedback channels, one for each of voltage, current, and motor speed lead to a microcontroller or microprocessor (18). The three feedback waveforms are analyzed, and from these waveforms, motor input power, patient heart rate, current pump flow rate, and systemic pressure are determined. The microprocessor (18) then calculates a desired flow rate proportional to the patient heart rate. The microprocessor communicates a new power output to a commutation circuit (16), which regulates power to the motor (12). The pump (10) also includes safety checks that are prioritized over desired pump flow. These include prevention of ventricular suction, low pulsatility, minimum and maximum pump speed, minimum speed-relative pump flow, minimum absolute pump flow, minimum and maximum motor input power.
摘要翻译：在左心室辅助装置（LVAD）中，旋转动力血泵（10）由无刷DC马达（12）供电。电源（14）向马达（12）供电。三个反馈通道，一个用于每个电压，电流和电机速度，导致微控制器或微处理器（18）。分析三个反馈波形，并从这些波形中确定电机输入功率，患者心率，电流泵流量和全身压力。微处理器（18）然后计算与患者心率成比例的期望流率。微处理器将新的功率输出传送到换向电路（16），该换向电路调节电动机（12）的功率。泵（10）还包括优先于所需泵流量的安全检查。这些包括预防心室抽吸，低搏动，最小和最大泵速，最小速度相对泵流量，最小绝对泵流量，最小和最大电机输入功率。

10. 发明授权

US5324177A Sealless rotodynamic pump with radially offset rotor 失效
标题翻译：带径向偏移转子的无密封旋转动力泵
公开(公告)号：US5324177A
公开(公告)日：1994-06-28
申请号：US695312
申请日：1991-05-03
申请人： Leonard A. R. Golding , William A. Smith
发明人： Leonard A. R. Golding , William A. Smith
IPC分类号： A61M1/10 , F04D1/04 , F04D3/02 , F04D13/06 , F04D29/04 , F04D29/041 , F04D29/046 , F04D29/047 , F04B17/00
CPC分类号： F04D29/047 , A61M1/101 , A61M1/1015 , A61M1/1031 , F04D1/04 , F04D13/0673 , F04D29/0413 , F04D29/0467 , F04D3/02 , Y10S415/90
摘要： A sealless centrifugal blood pump is provided in which a rotatable impeller is supported in a pump housing by fluid bearings during operation. Rotational movement of the impeller is accomplished with an inverted motor for magnetically driving of the impeller and maintenance of the axial running position of the impeller relative to the housing. In an alternative embodiment, the axis of the rotor housing is radially displaced relative to the axes of drive element of the motor and the motor housing.
摘要翻译：提供了一种无缝离心血泵，其中可旋转的叶轮在操作期间通过流体轴承支撑在泵壳体中。叶轮的旋转运动通过用于驱动叶轮的反转电动机和相对于壳体维持叶轮的轴向运动位置来实现。在替代实施例中，转子壳体的轴线相对于电机和电动机壳体的驱动元件的轴线径向移位。

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