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1. 发明授权

US06206841B1 Method and apparatus for obtaining blood for diagnostic tests 有权
标题翻译：血液检测方法及装置
公开(公告)号：US06206841B1
公开(公告)日：2001-03-27
申请号：US09546948
申请日：2000-04-11
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Thomas G. Schapira
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Thomas G. Schapira
IPC分类号： A61B500
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and (b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing. In another aspect of this invention, an article is provided for an article capable of both collecting blood and detecting an analyte in that blood is provided. The article, which contains an appropriate detection element for determining the amount of analyte in the blood, can be used in conjunction with a meter that measures the signal generated by the detection element of the article. In one embodiment, the article is a multiple-layer element comprising: (a) a layer capable of receiving blood and transporting the blood received by means of chemically aided wicking; (b) a layer capable of detecting the presence of analyte or measuring the amount of analyte in blood; and (c) a layer that can be placed in contact with a meter, the meter-contactable layer overlying the blood-transporting layer, said layer (a) capable of transporting blood to said layer (b).
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 并且（b）借助于皮肤的真空和拉伸，从皮肤中的无障碍的开口提取血液样品。在本发明的另一方面，提供了一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 优选地，该装置还包括壳体。在本发明的另一方面，提供了一种能够收集血液并检测血液中的分析物的物品。包含用于确定血液中分析物的量的合适的检测元件的物品可以与测量由物品的检测元件产生的信号的计量器结合使用。在一个实施方案中，制品是多层元件，其包括：（a）能够接收血液并通过化学辅助芯吸输送接收到的血液的层;（b）能够检测分析物的存在或测量血液中分析物的量; 以及（c）可以与仪表接触的层，覆盖在血液输送层上的可测量接触层，所述层（a）能够将血液输送到所述层（b）。

2. 发明授权

US6071251A Method and apparatus for obtaining blood for diagnostic tests 失效
标题翻译：血液检测方法及装置
公开(公告)号：US6071251A
公开(公告)日：2000-06-06
申请号：US982323
申请日：1997-12-02
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Thomas G. Schapira
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Thomas G. Schapira
IPC分类号： A61B5/151 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/15 , A61B5/154 , A61B5/157 , G01N33/48 , G01N33/66
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295 , A61B5/150358
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:(a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and(b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin.In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:(a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and(b) a vacuum pump.Preferably, the apparatus also includes a housing.In another aspect of this invention, an article is provided for an article capable of both collecting blood and detecting an analyte in that blood is provided. The article, which contains an appropriate detection element for determining the amount of analyte in the blood, can be used in conjunction with a meter that measures the signal generated by the detection element of the article. In one embodiment, the article is a multiple-layer element comprising:(a) a layer capable of receiving blood and transporting the blood received by means of chemically aided wicking;(b) a layer capable of detecting the presence of analyte or measuring the amount of analyte in blood; and(c) a layer that can be placed in contact with a meter, the meter-contactable layer overlying the blood-transporting layer, said layer (a) capable of transporting blood to said layer (b).
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 和（b）借助于真空和皮肤拉伸从皮肤中的无阻塞的开口提取血液样品。在本发明的另一方面，提供一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。在本发明的另一方面，提供了一种能够收集血液并检测血液中分析物的物品。包含用于确定血液中分析物的量的合适的检测元件的物品可以与测量由物品的检测元件产生的信号的计量器结合使用。在一个实施方案中，制品是多层元件，其包括：（a）能够接收血液并通过化学辅助芯吸运送接收的血液的层; （b）能够检测分析物的存在或测量血液中分析物的量的层; 以及（c）可以与仪表接触的层，覆盖在血液输送层上的可测量接触层，所述层（a）能够将血液输送到所述层（b）。

3. 发明授权

US6093156A Method and apparatus for obtaining blood for diagnostic tests 失效
公开(公告)号：US6093156A
公开(公告)日：2000-07-25
申请号：US982721
申请日：1997-12-02
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
IPC分类号： A61B5/151 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/15 , A61B5/154 , A61B5/157 , G01N33/48 , G01N33/66
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295 , A61B5/150358
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:(a) placing a blood collection device over a region on the surface of the skin from which said sample is to be obtained,(b) forming a seal between said blood collection device and said surface of the skin,(c) creating a vacuum sufficient to result in said surface of the skin becoming stretched and engorged with blood,(d) triggering a lancing assembly and causing a lancet to penetrate said skin,(e) retracting said lancet,(f) withdrawing blood toward and onto a fluid collector, and(g) releasing the vacuum.In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:(a) a housing having a sealable chamber located therein and a sealable opening in fluid communication with said sealable chamber,(b) a power source,(c) a vacuum pump operably connected to said power source, said vacuum pump in communication with said sealable chamber,(d) a lancing assembly positioned within said housing, said lancing assembly capable of moving a lancet towards said sealable opening, and(e) a fluid collector positioned in said sealable chamber, said fluid collector in fluid communication with said sealable opening.

4. 发明授权

US06306104B1 Method and apparatus for obtaining blood for diagnostic tests 有权
标题翻译：血液检测方法及装置
公开(公告)号：US06306104B1
公开(公告)日：2001-10-23
申请号：US09612722
申请日：2000-07-10
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
IPC分类号： A61B500
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) placing a blood collection device over a region on the surface of the skin from which said sample is to be obtained, (b) forming a seal between said blood collection device and said surface of the skin, (c) creating a vacuum sufficient to result in said surface of the skin becoming stretched and engorged with blood, (d) triggering a lancing assembly and causing a lancet to penetrate said skin, (e) retracting said lancet, (f) withdrawing blood toward and onto a fluid collector, and (g) releasing the vacuum. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a housing having a sealable chamber located therein and a sealable opening in fluid communication with said sealable chamber, (b) a power source, (c) a vacuum pump operably connected to said power source, said vacuum pump in communication with said sealable chamber, (d) a lancing assembly positioned within said housing, said lancing assembly capable of moving a lancet towards said sealable opening, and (e) a fluid collector positioned in said sealable chamber, said fluid collector in fluid communication with said sealable opening.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）将血液收集装置放置在要获得所述样品的皮肤表面上的区域上，（b）在所述血液收集器之间形成密封装置和皮肤表面，（c）产生足以导致皮肤表面变得伸展和凝结的真空的真空，（d）触发穿刺组件并使刺血针穿透所述皮肤，（e）缩回所述刺血针，（f）朝向流体收集器排出血液，和（g）释放真空。在本发明的另一方面，提供一种用于执行前述方法的装置。该设备包括：（a）壳体，其中具有位于其中的可密封腔室和与所述可密封腔室流体连通的可密封开口，（b）动力源，（c）可操作地连接到所述动力源的真空泵，所述真空泵与所述可密封腔室连通，（d）位于所述壳体内的采血组件，所述穿刺组件能够将刺血针移向所述可密封开口，以及（e）定位在所述可密封腔室中的流体收集器，所述流体收集器处于流体连通具有所述可密封的开口。

5. 发明授权

US06837858B2 Method and apparatus for obtaining blood for diagnostic tests 失效
标题翻译：血液检测方法及装置
公开(公告)号：US06837858B2
公开(公告)日：2005-01-04
申请号：US09972444
申请日：2001-10-05
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Andrew J. Muetterties , Thomas G. Schapira , Geoffrey R. Chambers , Graham J. Hughes , Jared L. Watkin , Gary F. Prokop , Joshua P. Goldfarb
IPC分类号： A61B5/151 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/15 , A61B5/154 , A61B5/157 , G01N33/48 , G01N33/66
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) placing a blood collection device over a region on the surface of the skin from which said sample is to be obtained, (b) forming a seal between said blood collection device and said surface of the skin, (c) creating a vacuum sufficient to result in said surface of the skin becoming stretched and engorged with blood, (d) triggering a lancing assembly and causing a lancet to penetrate said skin, (e) retracting said lancet, (f) withdrawing blood toward and onto a fluid collector, and (g) releasing the vacuum. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a housing having a sealable chamber located therein and a sealable opening in fluid communication with said sealable chamber, (b) a power source, (c) a vacuum pump operably connected to said power source, said vacuum pump in communication with said sealable chamber, (d) a lancing assembly positioned within said housing, said lancing assembly capable of moving a lancet towards said sealable opening, and (e) a fluid collector positioned in said sealable chamber, said fluid collector in fluid communication with said sealable opening.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）将血液收集装置放置在要获得所述样品的皮肤表面上的区域上，（b）在所述血液收集器之间形成密封装置和皮肤表面，（c）产生足以导致皮肤表面变得伸展和凝结的真空的真空，（d）触发穿刺组件并使刺血针穿透所述皮肤，（e）缩回所述刺血针，（f）朝向流体收集器排出血液，和（g）释放真空。在本发明的另一方面，提供一种用于执行前述方法的装置。该设备包括：（a）壳体，其中具有位于其中的可密封腔室和与所述可密封腔室流体连通的可密封开口，（b）动力源，（c）可操作地连接到所述动力源的真空泵，所述真空泵与所述可密封腔室连通，（d）位于所述壳体内的采血组件，所述穿刺组件能够将刺血针移向所述可密封开口，以及（e）定位在所述可密封腔室中的流体收集器，所述流体收集器处于流体连通具有所述可密封的开口。

6. 发明授权

US06071249A Method and apparatus for obtaining blood for diagnostic tests 失效
标题翻译：血液检测方法及装置
公开(公告)号：US06071249A
公开(公告)日：2000-06-06
申请号：US982324
申请日：1997-12-02
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Hugh W. Graham
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young , Michael G. Lowery , Hugh W. Graham
IPC分类号： A61B5/151 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/15 , A61B5/154 , A61B5/157 , G01N33/48 , G01N33/66
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295 , A61B5/150358
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:(a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and(b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin.In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:(a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and(b) a vacuum pump.Preferably, the apparatus also includes a housing.It has also been discovered that an improved design and construction of the nosepiece can provide enhanced collection of blood from the unobstructed opening in the skin. It has been discovered that by controlling the construction of the interior cavity of the nosepiece, collection of blood can be improved.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 和（b）借助于真空和皮肤拉伸从皮肤中的无阻塞的开口提取血液样品。在本发明的另一方面，提供一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。还已经发现，鼻梁的改进的设计和结构可以提供来自皮肤中无障碍开口的血液的增强的收集。已经发现，通过控制鼻梁的内腔的构造，可以提高血液的收集。

7. 发明授权

US06027459A Method and apparatus for obtaining blood for diagnostic tests 失效
标题翻译：血液检测方法及装置
公开(公告)号：US06027459A
公开(公告)日：2000-02-22
申请号：US982561
申请日：1997-12-02
申请人： Eric B. Shain , Michael G. Lowery , David D. Cunningham , Timothy P. Henning , Douglas F. Young
发明人： Eric B. Shain , Michael G. Lowery , David D. Cunningham , Timothy P. Henning , Douglas F. Young
IPC分类号： A61B5/151 , A61B5/00 , A61B5/145 , A61B5/1459 , A61B5/1473 , A61B5/15 , A61B5/154 , A61B5/157 , G01N33/48 , G01N33/66 , A61B10/00
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295 , A61B5/150358
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:(a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and(b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin.In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:(a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and(b) a vacuum pump.Preferably, the apparatus also includes a housing.In a further aspect of the invention, a pneumatic lancing assembly is provided. The pneumatic lancing assembly uses differential gas pressure to thrust a lancet into skin tissue. This lancing assembly effectively utilizes low-pressure gas, which is preferably provided by the aforementioned vacuum pump, and high-pressure gas, which is preferably provided by ambient air surrounding the apparatus, to thrust the lancet, puncture the skin, and then retract the lancet from the skin to produce an unobstructed opening to allow access to biological fluid.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 和（b）借助于真空和皮肤拉伸从皮肤中的无阻塞的开口提取血液样品。在本发明的另一方面，提供一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。在本发明的另一方面，提供一种气动采血组件。气动采血组件使用差压气体将刺血针推入皮肤组织。这种穿刺组件有效地利用优选由上述真空泵提供的低压气体和优选由围绕设备的环境空气提供的高压气体，以推动刺血针，刺穿皮肤，然后将刺血针从皮肤产生无阻碍的开口，以允许进入生物流体。

8. 发明授权

US06283926B1 Method and apparatus for obtaining blood for diagnostic tests 有权
标题翻译：血液检测方法及装置
公开(公告)号：US06283926B1
公开(公告)日：2001-09-04
申请号：US09532729
申请日：2000-03-22
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young
IPC分类号： A61B500
CPC分类号： A61B5/411 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150412 , A61B5/15136 , A61B5/157
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and (b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 并且（b）借助于皮肤的真空和拉伸，从皮肤中的无障碍的开口提取血液样品。在本发明的另一方面，提供了一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。

9. 发明授权

US06155992A Method and apparatus for obtaining interstitial fluid for diagnostic tests 失效
标题翻译：用于诊断测试的获得间质液的方法和装置
公开(公告)号：US06155992A
公开(公告)日：2000-12-05
申请号：US982449
申请日：1997-12-02
申请人： Timothy P. Henning , Robert G. Hiltibran , David D. Cunningham , Eric B. Shain , Brian J. Tarkowski , Douglas F. Young
发明人： Timothy P. Henning , Robert G. Hiltibran , David D. Cunningham , Eric B. Shain , Brian J. Tarkowski , Douglas F. Young
IPC分类号： A61B5/151 , A61B5/00 , A61B5/1455 , A61B5/1477 , A61B5/15 , A61B10/00
CPC分类号： A61B5/14514 , A61B10/0045 , A61B5/14532 , A61B2010/008 , A61M2037/0007
摘要： A method and apparatus for obtaining a sample of interstitial fluid from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of (a) treating an area of the skin with vacuum or heat or both vacuum and heat to increase the availability of interstitial fluid at that area of the skin; (b) forming an opening in the treated area of the skin; and (c) extracting the sample of interstitial fluid from the opening in the skin, with the aid of vacuum and stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. Th apparatus comprises (a) a device for forming an unobstructed opening in the area of the skin from which the sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing.
摘要翻译：一种从患者获得间质液样品的方法和装置，用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，该方法包括以下步骤：（a）用真空或热或真空和热处理皮肤区域，以增加皮肤区域间隙液的可用性; （b）在皮肤的处理区域中形成开口; 并且（c）借助真空和皮肤拉伸从皮肤开口提取间质液样品。在本发明的另一方面，提供一种用于执行前述方法的装置。 Th装置包括（a）用于在要从其中提取样品的皮肤区域中形成无障碍的开口的装置，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。

10. 发明授权

US6063039A Method and apparatus for obtaining blood for diagnostic tests 失效
标题翻译：血液检测方法及装置
公开(公告)号：US6063039A
公开(公告)日：2000-05-16
申请号：US759698
申请日：1996-12-06
申请人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young
发明人： David D. Cunningham , Timothy P. Henning , Eric B. Shain , Douglas F. Young
IPC分类号： A61B5/00 , A61B5/15 , A61B10/00
CPC分类号： A61B5/411 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150412 , A61B5/157 , A61B5/14532 , A61B5/15136
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:(a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and(b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin.In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:(a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and(b) a vacuum pump.Preferably, the apparatus also includes a housing.
摘要翻译：用于从患者获得血样的方法和装置用于随后的诊断测试，例如葡萄糖监测。在本发明的一个方面，所述方法包括以下步骤：（a）在要从其中提取血液样本的皮肤区域中形成无障碍的开口; 和（b）借助于真空和皮肤拉伸从皮肤中的无阻塞的开口提取血液样品。在本发明的另一方面，提供一种用于执行前述方法的装置。该装置包括：（a）用于在皮肤区域形成无障碍的开口的装置，所述皮肤区域将从所述皮肤区域中提取所述样品，优选为采血组件; 和（b）真空泵。优选地，该装置还包括壳体。

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