专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20080124363A1 Attenuated uracil auxotroph of an apicomplexan and use thereof 有权
标题翻译：一种apicomplexan的减毒尿嘧啶营养缺陷型及其用途
公开(公告)号：US20080124363A1
公开(公告)日：2008-05-29
申请号：US11962584
申请日：2007-12-21
申请人： David Bzik , Barbara Fox
发明人： David Bzik , Barbara Fox
IPC分类号： A61K39/00 , C07H21/00 , C12Q1/02 , A61P43/00 , C12N1/10
CPC分类号： A61K39/012 , A61K2039/522 , C12N9/93 , G01N33/56905 , Y02A50/58
摘要： Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
摘要翻译：提供了缺乏功能性氨基甲酰磷酸合成酶II（CPSII）酶的复合物的尿嘧啶营养缺陷型突变体。还提供了表达外源抗原的弓形虫自体突变体，以及保护动物抵抗弓形虫和非T型的方法。弓形虫病

2. 发明授权

US08293224B2 Attenuated uracil auxotroph of an apicomplexan and use thereof 有权
标题翻译：一种apicomplexan的减毒尿嘧啶营养缺陷型及其用途
公开(公告)号：US08293224B2
公开(公告)日：2012-10-23
申请号：US11962584
申请日：2007-12-21
申请人： David Bzik , Barbara Fox
发明人： David Bzik , Barbara Fox
IPC分类号： A01N63/00 , A61K39/09 , A61K39/012 , A61K39/00
CPC分类号： A61K39/012 , A61K2039/522 , C12N9/93 , G01N33/56905 , Y02A50/58
摘要： Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
摘要翻译：提供了缺乏功能性氨基甲酰磷酸合成酶II（CPSII）酶的复合物的尿嘧啶营养缺陷型突变体。还提供了表达外源抗原的弓形虫自体突变体，以及保护动物抵抗弓形虫和非T型的方法。弓形虫病

3. 发明申请

US20070172502A1 Compositions and methods for treatment of Toxoplasma gondii and other apicomplexans 审中-公开
标题翻译：组合物和方法治疗弓形虫和其他apicomplexans
公开(公告)号：US20070172502A1
公开(公告)日：2007-07-26
申请号：US11489701
申请日：2006-07-18
申请人： David Bzik , Barbara Fox
发明人： David Bzik , Barbara Fox
IPC分类号： A61K39/012 , G01N33/569 , C07H21/04 , C12N1/10
CPC分类号： C12Q1/025
摘要： Pyrimidine auxotroph mutants of apicomplexans are provided which are mutated in one of six enzymes of the de novo pyrimidine biosynthesis pathway. Also provided are methods of protecting an animal against infection by apicomplexans by administering a pyrimidine auxotroph mutant and methods for screening for inhibitors of pyrimidine salvage enzymes in apicomplexans.
摘要翻译：提供了apicomplexans的嘧啶营养缺陷突变体，其在重新嘧啶生物合成途径的六种酶之一中突变。还提供了通过施用嘧啶营养缺陷型突变体和用于筛选复合体中嘧啶补救酶抑制剂的方法来保护动物免受apicomplexans感染的方法。

4. 发明申请

US20060286097A1 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same 审中-公开
公开(公告)号：US20060286097A1
公开(公告)日：2006-12-21
申请号：US11472221
申请日：2006-06-19
申请人： Philiip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
发明人： Philiip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
IPC分类号： A61K39/395 , A61K39/00 , C07D451/02 , C07K16/18 , C07K14/47
CPC分类号： C07K16/44 , A61K39/0013 , A61K47/6425 , A61K47/646 , A61K2039/505 , A61K2039/6037
摘要： Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.

5. 发明申请

US20060280735A1 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same 审中-公开
公开(公告)号：US20060280735A1
公开(公告)日：2006-12-14
申请号：US11472216
申请日：2006-06-19
申请人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
发明人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
IPC分类号： A61K39/395 , A61K39/00 , C07K16/18 , C07K14/47
CPC分类号： C07K16/44 , A61K39/0013 , A61K47/6425 , A61K47/646 , A61K2039/505 , A61K2039/6037
摘要： Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.

6. 发明申请

US20050138363A1 Certificate reissuance for checking the status of a certificate in financial transactions 有权
标题翻译：用于检查金融交易中证书状态的证书重新发行
公开(公告)号：US20050138363A1
公开(公告)日：2005-06-23
申请号：US11032833
申请日：2005-01-10
申请人： Barbara Fox , Brian LaMacchia
发明人： Barbara Fox , Brian LaMacchia
IPC分类号： H04L9/32 , H04L9/00
CPC分类号： H04L9/3263 , H04L2209/56
摘要： A system for using a certificate authority to first provide a customer with a digital certificate, and then having a relying party that receives that digital certificate access a status authority (the certificate authority or its designated agent) to receive a reissued certificate on that certificate. The reissued certificate has a much shorter validity period, which ensures that the information is timely. Moreover, the certificate may serve as a receipt, including an accumulated record of the signatures (digital certificates) and policy applied throughout the financial transaction. As a result, each transfer of the transaction forms a digitally-signed chain of evidence recording each step of the transaction and policy applied thereto, whereby risk may be assumed and charged for appropriately and in accordance with the risk purchaser's policy.
摘要翻译：一种使用证书颁发机构首先向客户提供数字证书，然后使具有接收该数字证书的依赖方访问状态授权机构（认证机构或其指定代理人）以在该证书上接收重发证书的系统。重发证书的有效期短得多，确保信息及时。此外，证书可以作为收据，包括在整个金融交易中应用的签名（数字证书）和政策的累积记录。因此，交易的每次转让形成数字签名的证据链，记录交易的每个步骤和适用的政策，从而适当地并根据风险购买者的政策来承担风险并收取风险。

7. 发明申请

US20060286098A1 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same 审中-公开
公开(公告)号：US20060286098A1
公开(公告)日：2006-12-21
申请号：US11472222
申请日：2006-06-19
申请人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
发明人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Stephen Powers , Malcolm Gefter
IPC分类号： C07K16/18 , C07K14/47 , C07D451/02 , A61K39/395 , A61K39/00
CPC分类号： C07K16/44 , A61K39/0013 , A61K47/6425 , A61K47/646 , A61K2039/505 , A61K2039/6037
摘要： Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.

8. 发明申请

US20060069590A1 Intelligent trust management method and system 有权
公开(公告)号：US20060069590A1
公开(公告)日：2006-03-30
申请号：US11273143
申请日：2005-11-14
申请人： Barbara Fox , Brian LaMacchia
发明人： Barbara Fox , Brian LaMacchia
IPC分类号： G06Q99/00
CPC分类号： G06F21/50 , G06F21/52 , G06F21/604 , G06Q40/00
摘要： Intelligent Trust Management provides a centralized security facility that gives system components a flexible mechanism for implementing security policies. System components such as applications create a request describing an action that needs to be checked against an appropriate security policy. The request is given to a trust system that determines which policy object applies to the request, and may pass request arguments to the policy. The policy objects include executable code that uses any arguments along with dynamically obtained variable information to make a decision. The decision is returned to the system component, which then operates accordingly. Policy objects may maintain state and interface with the user independent of the system component in order to obtain information to make their decisions. Policy objects may call other policy objects and/or mathematically combine the results of other policy objects to make a decision.

9. 发明授权

US07366918B2 Configuring and managing resources on a multi-purpose integrated circuit card using a personal computer 有权
标题翻译：使用个人计算机配置和管理多用途集成电路卡上的资源
公开(公告)号：US07366918B2
公开(公告)日：2008-04-29
申请号：US10845690
申请日：2004-05-14
申请人： Doug Barlow , Blair Dillaway , Barbara Fox , Terry Lipscomb , Terrence Spies
发明人： Doug Barlow , Blair Dillaway , Barbara Fox , Terry Lipscomb , Terrence Spies
IPC分类号： G06F11/30 , G06F12/14 , H04L9/32 , H04L9/00 , H04N7/16 , G06F15/16 , G06F17/30
CPC分类号： G07F7/1008 , G06Q20/105 , G06Q20/341 , G06Q20/3552 , G06Q20/35765 , G06Q20/367 , G06Q20/3672 , G06Q20/40
摘要： The systems and methods provide for configuring and managing resources on a multi-purpose IC card. In one aspect, a user interface (UI) for an application is presented on a display device. A user is enabled via at least one graphical dialog screen of the UI to configure a communicatively coupled IC card. Management of one or more resources on the IC card is facilitated via at least one graphical dialog screen of the UI.
摘要翻译：这些系统和方法提供了在多功能IC卡上配置和管理资源。在一个方面，用于应用的用户界面（UI）被呈现在显示设备上。经由UI的至少一个图形对话屏幕启用用户以配置通信耦合的IC卡。通过UI的至少一个图形对话屏来促进IC卡上的一个或多个资源的管理。

10. 发明申请

US20060286096A1 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same 审中-公开
公开(公告)号：US20060286096A1
公开(公告)日：2006-12-21
申请号：US11472220
申请日：2006-06-19
申请人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Malcolm Gefter , Stephen Powers
发明人： Philip Swain , Victoria Schad , Julia Greenstein , Mark Exley , Barbara Fox , Malcolm Gefter , Stephen Powers
IPC分类号： C07K14/47 , C07D451/02 , C07K16/18 , A61K39/395 , A61K39/00
CPC分类号： C07K16/44 , A61K39/0013 , A61K47/6425 , A61K47/646 , A61K2039/505 , A61K2039/6037
摘要： Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式