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1. 发明申请

US20070064135A1 Apparatus for continuous clocking of TDI sensors 有权
标题翻译：用于连续计时TDI传感器的装置
公开(公告)号：US20070064135A1
公开(公告)日：2007-03-22
申请号：US11292754
申请日：2005-12-01
申请人： David Brown , Kai Cao , Yung-Ho Chuang
发明人： David Brown , Kai Cao , Yung-Ho Chuang
IPC分类号： H04N5/335
CPC分类号： H04N5/3765 , H04N5/37206
摘要： A method and apparatus for propagating charge through a sensor and implementation thereof is provided. The method and apparatus may be used to inspect specimens, the sensor operating to advance an accumulated charge between gates of the TDI sensor. The design implementation provides a set of values representing a plurality of out of phase signals, such as sinusoidal or trapezoidal signals. These out of phase signals are converted and transmitted to the sensor. The converted signals cause the sensor to transfer charges in the sensor toward an end of the sensor. Aspects such as feed through correction and correction of nonlinearities are addressed.
摘要翻译：提供了一种通过传感器传播电荷的方法和装置及其实现。该方法和装置可用于检查样品，传感器操作以提前TDI传感器的门之间的累积电荷。设计实现提供了一组表示多个异相信号的值，例如正弦或梯形信号。这些异相信号被转换并传输到传感器。转换的信号使传感器将传感器中的电荷传送到传感器的一端。解决馈线通过校正和校正非线性等方面。

2. 发明申请

US20060266926A1 System and method for sensing using adjustable modulation transfer function (MTF) 有权
公开(公告)号：US20060266926A1
公开(公告)日：2006-11-30
申请号：US11500232
申请日：2006-08-04
申请人： Yung-Ho Chuang , J. Armstrong , David Brown , Bin-Ming Tsai
发明人： Yung-Ho Chuang , J. Armstrong , David Brown , Bin-Ming Tsai
IPC分类号： H01L27/00
CPC分类号： H01L27/14625 , H04N5/3559 , H04N5/357
摘要： A variable modulated transfer function (MTF) design employing a variable gate voltage source for use in inspecting specimens is disclosed. The design applies a variable gate voltage to each pixel of a sensor, wherein applying the variable gate voltage to each pixel adjusts the MTF of the pixel. MTF adjustment improves adverse effects encountered during inspection, such as aliasing and maintaining contrast.

3. 发明申请

US20060103725A1 Continuous clocking of TDI sensors 有权
公开(公告)号：US20060103725A1
公开(公告)日：2006-05-18
申请号：US10992063
申请日：2004-11-18
申请人： David Brown , Yung-Ho Chuang
发明人： David Brown , Yung-Ho Chuang
IPC分类号： H04N5/335 , H04N7/18
CPC分类号： H04N5/37206 , H04N5/372
摘要： A method and apparatus for propagating charge through a time division and integration (TDI) sensor is provided. The method and apparatus may be used with the TDI sensor to inspect specimens, the TDI sensor operating to advance an accumulated charge between gates of the TDI sensor. The design comprises controlling voltage waveform shapes for waveforms advancing the accumulated charge between gates in a substantially nonsquare waveform, such as a composite, sinusoidal, or other shaped waveform. Controlling voltage waveform shapes operates at different voltage phases in adjacent gates to provide a substantially de minimis net voltage.

4. 发明申请

US20070121107A1 Excimer laser inspection system 有权
标题翻译：准分子激光检查系统
公开(公告)号：US20070121107A1
公开(公告)日：2007-05-31
申请号：US11594625
申请日：2006-11-08
申请人： Bin-Ming Tsai , Yung-Ho Chuang , J. Armstrong , David Brown
发明人： Bin-Ming Tsai , Yung-Ho Chuang , J. Armstrong , David Brown
IPC分类号： G01N21/88
CPC分类号： G02B17/0808 , G01N21/8806 , G01N21/9501 , G01N21/95607 , G01N2021/479 , G01N2021/8825 , G01N2021/95676 , G01N2201/06113 , G02B17/0856 , G02B17/0892 , G02B21/04 , G03F7/70225
摘要： A system and method for inspecting a specimen, such as a semiconductor wafer, including illuminating at least a portion of the specimen using an excimer source using at least one relatively intense wavelength from the source, detecting radiation received from the illuminated portion of the specimen, analyzing the detected radiation for potential defects present in the specimen portion.
摘要翻译：一种用于检查诸如半导体晶片的样本的系统和方法，包括使用来自所述源的至少一个相对较强的波长的准分子源照射所述样本的至少一部分，检测从所述被照射部分接收的辐射，分析检测到的辐射对于存在于样品部分中的潜在缺陷。

5. 发明申请

US20070146693A1 Method and apparatus for simultaneous high-speed acquisition of multiple images 有权
标题翻译：同时高速采集多幅图像的方法和装置
公开(公告)号：US20070146693A1
公开(公告)日：2007-06-28
申请号：US11318715
申请日：2005-12-27
申请人： David Brown , Yung-Ho Chuang
发明人： David Brown , Yung-Ho Chuang
IPC分类号： G01N21/88
CPC分类号： G01N21/95607
摘要： A method and apparatus for simultaneous high-speed inspection and acquisition of multiple data channels is provided. The method and apparatus enables inspecting semiconductor wafers and reticles and comprises converting a single image region into two image sections, reorienting one image into a transposed configuration enabling simultaneous scanning of two inspected object locations with a single sensor, and controlling acquisition parameters for a second image by using information collected from a first image in a feedback arrangement. The design provides a dual-linear or time-delay-integration sensor operating in a split readout configuration mode to simultaneously provide data from two regions of the sensor using two sets of readout circuitry.
摘要翻译：提供了用于同时高速检查和获取多个数据信道的方法和装置。该方法和装置能够检测半导体晶片和标线，并且包括将单个图像区域转换成两个图像部分，将一个图像重新定向为转置配置，使得能够利用单个传感器同时扫描两个检查对象位置，并且控制第二图像的获取参数通过使用从反馈安排中的第一图像收集的信息。该设计提供了以分离读出配置模式工作的双线性或时间延迟积分传感器，以使用两组读出电路同时从传感器的两个区域提供数据。

6. 发明申请

US20070249615A1 Pyridine [3,4-b] Pyrazinones 有权
标题翻译：吡啶[3,4-b]吡嗪酮
公开(公告)号：US20070249615A1
公开(公告)日：2007-10-25
申请号：US11737966
申请日：2007-04-20
申请人： Robert Hughes , Andrew Bell , David Brown , Dafydd Owen , Michael Palmer , Christopher Phillips , David Brown , Yvette Fobian , John Freskos , Steven Heasley , E. Jacobsen , Todd Maddux , Brent Mischke , John Molyneaux , Joseph Moon , D. Rogier , Michael Tollefson , John Walker
发明人： Robert Hughes , Andrew Bell , David Brown , Dafydd Owen , Michael Palmer , Christopher Phillips , David Brown , Yvette Fobian , John Freskos , Steven Heasley , E. Jacobsen , Todd Maddux , Brent Mischke , John Molyneaux , Joseph Moon , D. Rogier , Michael Tollefson , John Walker
IPC分类号： A61K31/498 , C07D487/02
CPC分类号： C07D471/04
摘要： Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein R2, R6A, R6B and R8 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, synthetic methods, and intermediates are also disclosed.
摘要翻译：公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有式I的结构：其中R 2，R 6A，R 6B， >和R＆gt; 8如说明书中所定义。还公开了相应的药物组合物，治疗方法，合成方法和中间体。

7. 发明公开

US20240026317A1 PAN-RAS mRNA CANCER VACCINES 审中-公开
公开(公告)号：US20240026317A1
公开(公告)日：2024-01-25
申请号：US18249023
申请日：2021-10-13
申请人： Dong SHEN , David BROWN , Renxiang CHEN , RNAimmune, Inc
发明人： Dong Shen , David Brown , Renxiang Chen
IPC分类号： C12N9/14 , C12P19/30 , A61K39/00 , A61K9/127 , A61K47/69 , A61P35/00 , A61K47/54
CPC分类号： C12N9/14 , C12Y306/05002 , C12P19/30 , A61K39/001164 , A61K9/1273 , A61K47/6911 , A61P35/00 , A61K47/54 , A61K2039/53 , A61K2039/585 , A61K2039/55555
摘要： Compositions and methods are provided for potent mRNA vaccines for treatment of cancers with a mutation in the ras gene family. The compositions include a pharmaceutical composition comprising, or consisting essentially of, or yet further comprising mRNA molecules encoding at least one of multiple peptides of a group of somatic mutants and a pharmaceutically acceptable carrier. Methods for stimulating system immune responses and treatment are provided, including intratumoral, intravenous, intramuscular, intradermal, or subcutaneous injection of the composition as disclosed herein.

8. 发明授权

US11345606B2 Deposition particles and a method and apparatus for producing the same 有权
公开(公告)号：US11345606B2
公开(公告)日：2022-05-31
申请号：US15435318
申请日：2017-02-17
申请人： David Brown
发明人： David Brown
IPC分类号： G02B6/02 , C01G23/053 , C01G49/06 , C01B33/18
摘要： Disclosed is a method for producing deposition particles or intermediate particles, characterized in that the method comprises: forming a solution comprising a solvent and one or more deposit sources, aerosolizing the formed solution to produce an aerosol of precursor particles comprising the deposit source, conditioning the precursor particles to produce deposition particles or intermediate particles from the deposit source and collecting said particles. The particles may be collected as a deposit or precursor deposit on a substrate. The particles may include a matrix material and a dopant. The conditioning may be quenched to produce a desired substructure. The matrix material may be essentially optically clear. The substrate may comprise an optical fiber or an optical fiber preform or mandrel.

9. 外观设计

USD819777S1 Fishing lure mold 有权
公开(公告)号：USD819777S1
公开(公告)日：2018-06-05
申请号：US29581051
申请日：2016-10-14
申请人： David Brown
设计人： David Brown

10. 发明申请

US20170128079A1 ADJUSTABLE CUT BLOCK AND SIZER INSTRUMENT FOR ARTHROPLASTY PLANNING 审中-公开
公开(公告)号：US20170128079A1
公开(公告)日：2017-05-11
申请号：US15343765
申请日：2016-11-04
申请人： David Brown
发明人： David Brown
IPC分类号： A61B17/15
CPC分类号： A61B17/155
摘要： An integrated instrument for arthroplasty planning comprises a cutting block having an adjustable distance between an anterior cut guide and a posterior cut guide, and a sizer mounted to the cutting block, the sizer comprising medial and lateral posterior feet having an adjustable distance from one of the cut guides and an adjustable angular position relative to the one of the cut guides.

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