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    • 3. 发明授权
    • Ultramulsion based oral care rinse compositions
    • 基于超乳液的口腔护理漂洗组合物
    • US5645841A
    • 1997-07-08
    • US462930
    • 1995-06-05
    • Ira D. HillPeter P. WaltersDale G. Brown
    • Ira D. HillPeter P. WaltersDale G. Brown
    • A61K8/06A61K8/49A61K8/891A61K8/90A61Q11/00A61K6/00
    • A61Q11/00A61K8/06A61K8/4946A61K8/891A61K8/90A61K2800/21A61K2800/222
    • The present invention relates to various oral care rinses containing, stable, dispersions of certain high viscosity silicones in certain surfactants; wherein:a. the dispersed silicones, which are insoluble in said surfactant, are oriented by the surfactant such that when dispersed in water they are particularly adept at forming oriented, coatings on surfaces of the mouth with enhanced substantivity, andb. the particle size of the dispersed silicone is from between about 0.1 and about 10 microns, with a particle size distribution such that from between about 80 and 95% of the dispersed silicone is within this particle size range. These stable dispersions are described as ULTRAMULSION.TM. dispersions, which, together with their physical properties, when contained in oral care rinses, provide these rinses with enhanced substantivity to mouth surfaces, where the non continuous silicone phase functions as a reservoir for various active ingredients contained therein, including but not limited to an essential mixture of thymol, eucalyptol, menthol and methyl salicylate.
    • 本发明涉及在某些表面活性剂中含有某些高粘度硅氧烷的稳定,分散的各种口腔护理漂洗液; 其中:a。 不溶于所述表面活性剂的分散硅氧烷通过表面活性剂取向,使得当分散在水中时,它们特别适用于形成具有增强的亲和力的嘴表面上的取向的涂层,以及b。 分散的硅氧烷的粒度为约0.1至约10微米,其粒度分布使分散的硅氧烷的约80至95%在该粒度范围内。 这些稳定的分散体被描述为ULTRAMULSION TM分散体,当它们包含在口腔护理漂洗液中时,它们与它们的物理性质一起提供这些漂洗剂对口腔表面具有增强的亲和性,其中非连续硅氧烷相作为包含各种活性成分的储器 其中包括但不限于百里酚,桉树脑,薄荷醇和水杨酸甲酯的必要混合物。
    • 5. 发明授权
    • Ultramulsion based ingestible compositions
    • 基于超乳液的可摄取组合物
    • US5711936A
    • 1998-01-27
    • US464403
    • 1995-06-05
    • Ira D. HillPeter P. WaltersDale G. Brown
    • Ira D. HillPeter P. WaltersDale G. Brown
    • A61K8/06A61K8/49A61K8/891A61K8/90A61Q11/00A61K7/16A61K31/74
    • A61Q11/00A61K8/06A61K8/4946A61K8/891A61K8/90A61K9/006A61K9/0095A61K9/2018A61K2800/21A61K2800/222
    • The present invention relates to various ingestible products containing stable, dispersions of certain high viscosity silicones in certain surfactants for use in treating mucus containing surfaces such as in the mouth, throat and stomach and intestine and the surface of the esophagus which contains no mucus. a. the dispersed silicones, which are insoluble in said surfactant, are oriented by the surfactant such that when dispersed in water they are particularly adept at forming oriented coatings on mouth, throat and esophagus and stomach surfaces with enhanced substantivity, and b. the particle size of the dispersed silicone is from between about 0.1 and about 10 microns, with a particle size distribution such that from substantially all of the dispersed silicone is within this particle size range. These stable dispersions are described as ULTRAMULSION.TM. dispersions, which, together with their physical properties, when contained in mouth, throat, esophagus, stomach and intestine treatment properties, when contained in products, provide these products with substantive coating protection properties where the discontinuous silicone phase of said coating functions as a reservoir for various liquid suitable treatment substances, suitable for release onto the surface being treated.
    • 本发明涉及在某些表面活性剂中含有某些高粘度硅氧烷的稳定的分散体,用于治疗含有口腔,咽喉,胃和肠的粘液以及不含粘液的食管表面的各种可摄入产品。 一个。 不溶于所述表面活性剂的分散硅氧烷通过表面活性剂取向,使得当分散在水中时,它们特别适用于在具有增强的亲和性的口,咽喉和食管和胃表面上形成定向涂层,以及b。 分散的硅氧烷的粒度为约0.1至约10微米,其粒度分布使得从基本上所有分散的硅氧烷都在该粒度范围内。 这些稳定的分散体被描述为ULTRAMULSION TM分散体,当它们包含在产品中时,其与物理性质一起包含在口腔,咽喉,食管,胃和肠中的处理性质中,为这些产品提供实质的涂层保护性质,其中不连续的硅氧烷 所述涂层的相位用作用于各种液体适合的处理物质的储存器,适于释放到被处理的表面上。
    • 10. 发明授权
    • Ultramulsion based antigingivitis toothpaste compositions
    • 基于超乳液的防治牙龈炎牙膏组合物
    • US5733529A
    • 1998-03-31
    • US461698
    • 1995-06-05
    • Ira D. HillPeter P. WaltersDale G. Brown
    • Ira D. HillPeter P. WaltersDale G. Brown
    • A61K8/06A61K8/34A61K8/49A61K8/891A61K8/90A61Q11/00A61K7/16
    • A61K8/347A61K8/06A61K8/4946A61K8/891A61K8/90A61Q11/00A61K2800/21A61K2800/222
    • The present invention relates to various toothpastes containing, stable, dispersions of certain high viscosity silicones in certain surfactants; wherein: a. the dispersed silicones, which contain triclosan, 2,4,4'-triclosan-2'-hydroxy/epoxy/ether, are insoluble in said surfactant, are oriented by the surfactant such that when dispersed in water they are particularly adept at forming oriented, nonhelical coatings on surfaces of the mouth with enhanced substantivity, and b. the particle size of the dispersed silicone is from between about 0.1 and about 10 microns, with a particle size distribution such that from between about 80 and 95% of the dispersed silicone is within this particle size range. These stable dispersions are described as ULTRAMULSION dispersions, which, together with their physical properties, when contained in toothpastes, provide the toothpaste with enhanced with enhanced substantivity to mouth surfaces, where the non continuous silicone phase functions as a reservoir for the triclosan contained therein.
    • 本发明涉及在某些表面活性剂中含有某些高粘度硅氧烷的稳定的分散体的各种牙膏; 其中:a。 含有三氯生2,4,4'-三氯生-2'-羟基/环氧/醚的分散硅氧烷不溶于所述表面活性剂,由表面活性剂取向,使得当分散在水中时,它们特别适用于形成取向 ,嘴唇表面上的非线性涂层具有增强的亲和力,以及b。 分散的硅氧烷的粒度为约0.1至约10微米,其粒度分布使分散的硅氧烷的约80至95%在该粒度范围内。 这些稳定的分散体被描述为ULTRAMULSION分散体,当它们包含在牙膏中时,它们与它们的物理性质一起提供牙膏,其具有增强的口腔表面的增强的亲和性,其中非连续硅氧烷相用作其中所含的三氯生的储库。