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1. 发明申请

US20130046647A1 SYSTEM FOR MANAGING CONSTRUCTION PROJECT BIDDING 审中-公开
标题翻译：管理施工工程投标制度
公开(公告)号：US20130046647A1
公开(公告)日：2013-02-21
申请号：US13210774
申请日：2011-08-16
申请人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
发明人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
IPC分类号： G06Q30/08
CPC分类号： G06Q30/08 , G06Q10/00
摘要： A system is disclosed that facilitates construction project bidding, document distribution, and project management over a computer network. The system enables a project supervisor to efficiently transmit new project information and associated construction project files to one or more planroom provider systems. Each planroom provider system may make project information and associated construction project files available for transfer and viewing by one or more potential bidders connected to the planroom provider system over a public or private network. The planroom provider system(s) may provide a reference or link back to the project supervisor system to enable the potential bidder to bid on the construction project once the project information and project files have been reviewed.
摘要翻译：公开了一种通过计算机网络进行项目投标，文件分发和项目管理的系统。该系统使项目主管有效地将新的项目信息和相关的建设项目文件传送到一个或多个计划供应商系统。每个计划供应商系统可以使项目信息和相关的建设项目文件可供一个或多个通过公共或私人网络连接到计划室提供者系统的潜在投标人进行转移和查看。一旦项目信息和项目文件被审查，计划供应商系统可以提供参考或链接回项目主管系统，以使潜在投标人能够对施工项目进行投标。

2. 发明授权

US08412618B2 System for managing construction project bidding 有权
标题翻译：施工项目招标管理制度
公开(公告)号：US08412618B2
公开(公告)日：2013-04-02
申请号：US13210881
申请日：2011-08-16
申请人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
发明人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
IPC分类号： G06Q30/06 , G06Q20/02 , G06Q40/04 , G06Q40/06 , G06Q40/02 , G06Q50/16
CPC分类号： G06Q30/08
摘要： A system is disclosed that facilitates construction project bidding over a computer network. In one aspect, a construction project supervisor system may verify one or more aspects of bidder information before bidding. A bidder may submit payment information, an electronic mail address, and a telephone number to be verified. Verification may include utilizing the payment information to process a payment, and/or sending a verification code to the electronic mail address and/or telephone number. In one embodiment, the issuance of a bid bond associated with the prospective bid may be required to complete the verification process.
摘要翻译：公开了一种通过计算机网络促进建筑项目投标的系统。一方面，施工项目主管系统可以在出价之前验证投标人信息的一个或多个方面。投标人可以提交付款信息，电子邮件地址和要验证的电话号码。验证可以包括利用支付信息来处理支付，和/或向电子邮件地址和/或电话号码发送验证码。在一个实施例中，可能需要发行与预期投标相关联的投标保证金来完成验证过程。

3. 发明申请

US20130046672A1 SYSTEM FOR MANAGING CONSTRUCTION PROJECT BIDDING 有权
标题翻译：管理施工工程投标制度
公开(公告)号：US20130046672A1
公开(公告)日：2013-02-21
申请号：US13210881
申请日：2011-08-16
申请人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
发明人： Dave Robertson , Sharandeep Sekhon , Baohua Gu , Dariusz Czarkowski
IPC分类号： G06Q40/04
CPC分类号： G06Q30/08
摘要： A system is disclosed that facilitates construction project bidding over a computer network. In one aspect, a construction project supervisor system may verify one or more aspects of bidder information before bidding. A bidder may submit payment information, an electronic mail address, and a telephone number to be verified. Verification may include utilizing the payment information to process a payment, and/or sending a verification code to the electronic mail address and/or telephone number. In one embodiment, the issuance of a bid bond associated with the prospective bid may be required to complete the verification process.
摘要翻译：公开了一种通过计算机网络促进建筑项目投标的系统。一方面，施工项目主管系统可以在出价之前验证投标人信息的一个或多个方面。投标人可以提交付款信息，电子邮件地址和要验证的电话号码。验证可以包括利用支付信息来处理支付，和/或向电子邮件地址和/或电话号码发送验证码。在一个实施例中，可能需要发行与预期投标相关联的投标保证金来完成验证过程。

4. 发明授权

US06800203B2 Catalytic destruction of perchlorate in ferric chloride and hydrochloric acid solution with control of temperature, pressure and chemical reagents 失效
标题翻译：氯化铁和盐酸溶液中高氯酸盐的催化破坏，控制温度，压力和化学试剂
公开(公告)号：US06800203B2
公开(公告)日：2004-10-05
申请号：US10157407
申请日：2002-05-29
申请人： Baohua Gu , David R. Cole , Gilbert M. Brown
发明人： Baohua Gu , David R. Cole , Gilbert M. Brown
IPC分类号： C02F128
CPC分类号： B01J49/57 , C02F1/42 , C02F2101/12 , C02F2303/16 , C02F2303/18 , Y10S210/902
摘要： A method is described to decompose perchlorate in a FeCl3/HCl aqueous solution such as would be used to regenerate an anion exchange resin used to remove perchlorate. The solution is mixed with a reducing agent, preferably an organic alcohol and/or ferrous chloride, and can be heated to accelerate the decomposition of perchlorate. Lower temperatures may be employed if a catalyst is added.
摘要翻译：描述了一种方法来分解FeCl 3 / HCl水溶液中的高氯酸盐，例如用于再生用于除去高氯酸盐的阴离子交换树脂。将溶液与还原剂，优选有机醇和/或氯化亚铁混合，并且可以加热以加速高氯酸盐的分解。如果加入催化剂，可以采用较低的温度。

5. 发明授权

US09198927B2 Targeting opposite strand replication intermediates of single-stranded viruses by RNAI 有权
标题翻译：通过RNAI靶向单链病毒的反向链复制中间体
公开(公告)号：US09198927B2
公开(公告)日：2015-12-01
申请号：US12714949
申请日：2010-03-01
申请人： Daniel E. McCallus , Catherine Pachuk , Baohua Gu
发明人： Daniel E. McCallus , Catherine Pachuk , Baohua Gu
IPC分类号： C12N15/11 , A61K31/713 , C12N15/113 , C07H21/04
CPC分类号： A61K31/713 , C12N15/1131 , C12N2310/111 , C12N2310/14 , C12N2310/53 , Y02A50/463
摘要： The invention relates to methods and compositions for modulating viral replication through double-stranded RNA-mediated gene silencing (RNAi), wherein the antiviral methods and compositions preferentially target opposite strand replication intermediates of single-stranded RNA viruses.
摘要翻译：本发明涉及通过双链RNA介导的基因沉默（RNAi）调节病毒复制的方法和组合物，其中抗病毒方法和组合物优先靶向单链RNA病毒的相反链复制中间体。

6. 发明申请

US20120267585A1 VOLUME-LABELED NANOPARTICLES AND METHODS OF PREPARATION 审中-公开
公开(公告)号：US20120267585A1
公开(公告)日：2012-10-25
申请号：US13489618
申请日：2012-06-06
申请人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
发明人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
IPC分类号： C09K11/04 , C09K11/06 , B82Y30/00 , B82Y40/00
CPC分类号： C09K11/06 , B82Y30/00 , B82Y40/00 , C09K2211/1007 , C09K2211/1011 , C09K2211/1088 , H01F1/0054
摘要： Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

7. 发明申请

US20120168671A1 VOLUME-LABELED NANOPARTICLES AND METHODS OF PREPARATION 有权
标题翻译：体积标准的纳米颗粒及其制备方法
公开(公告)号：US20120168671A1
公开(公告)日：2012-07-05
申请号：US12981886
申请日：2010-12-30
申请人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
发明人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
IPC分类号： C09K11/04 , C09K11/08 , C09K11/02 , C09K11/06 , H01F1/00 , B82Y40/00 , B82Y30/00
CPC分类号： B82Y30/00 , B82Y40/00 , C09K11/04 , C09K11/06 , H01F1/0054
摘要： Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
摘要翻译：包含纳米尺寸物体（即，纳米颗粒）的组合物，其中至少一个可观察标记如放射性同位素或荧光团掺入纳米尺度物体内。纳米尺寸物体包括例如金属或半金属氧化物（例如二氧化硅），量子点，贵金属，磁性金属氧化物，有机聚合物，金属盐和核 - 壳纳米颗粒，其中标记掺入纳米颗粒内或选择性地在核 - 壳纳米颗粒的金属氧化物壳中。还描述了制备体积标记的纳米颗粒的方法。

8. 发明申请

US20090137039A1 TARGETING OPPOSITE STRAND REPLICATION INTERMEDIATES OF SINGLE-STRANDED VIRUSES BY RNAI 审中-公开
标题翻译： RNAI对单链病毒的针对性替代中间性
公开(公告)号：US20090137039A1
公开(公告)日：2009-05-28
申请号：US12201499
申请日：2008-08-29
申请人： Daniel E. McCALLUS , Catherine Pachuk , Baohua Gu
发明人： Daniel E. McCALLUS , Catherine Pachuk , Baohua Gu
IPC分类号： C12N5/08 , C12N5/06 , C12N15/11
CPC分类号： A61K31/713 , C12N15/1131 , C12N2310/111 , C12N2310/14 , C12N2310/53 , Y02A50/463
摘要： The invention relates to methods and compositions for modulating viral replication through double-stranded RNA-mediated gene silencing (RNAi), wherein the antiviral methods and compositions preferentially target opposite strand replication intermediates of single-stranded RNA viruses.
摘要翻译：本发明涉及通过双链RNA介导的基因沉默（RNAi）调节病毒复制的方法和组合物，其中抗病毒方法和组合物优先靶向单链RNA病毒的相反链复制中间体。

9. 发明授权

US09011735B2 Volume-labeled nanoparticles and methods of preparation 有权
标题翻译：体积标记的纳米颗粒和制备方法
公开(公告)号：US09011735B2
公开(公告)日：2015-04-21
申请号：US12981886
申请日：2010-12-30
申请人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
发明人： Wei Wang , Baohua Gu , Scott T. Retterer , Mitchel J. Doktycz
IPC分类号： C09K11/04 , C09K11/06 , C09K11/08 , B82Y40/00 , B82Y30/00 , H01F1/00
CPC分类号： B82Y30/00 , B82Y40/00 , C09K11/04 , C09K11/06 , H01F1/0054
摘要： Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
摘要翻译：包含纳米尺寸物体（即，纳米颗粒）的组合物，其中至少一个可观察标记如放射性同位素或荧光团掺入纳米尺度物体内。纳米尺寸物体包括例如金属或半金属氧化物（例如二氧化硅），量子点，贵金属，磁性金属氧化物，有机聚合物，金属盐和核 - 壳纳米颗粒，其中标记掺入纳米颗粒内或选择性地在核 - 壳纳米颗粒的金属氧化物壳中。还描述了制备体积标记的纳米颗粒的方法。

10. 发明授权

US07989211B1 Functionalized gold surface-enhanced raman scattering substrate for rapid and ultra-sensitive detection of anionic species in the environment 有权
标题翻译：功能化的金表面增强拉曼散射底物，用于环境中阴离子物质的快速和超灵敏检测
公开(公告)号：US07989211B1
公开(公告)日：2011-08-02
申请号：US12645017
申请日：2009-12-22
申请人： Baohua Gu , Chuanmin Ruan , Wei Wang
发明人： Baohua Gu , Chuanmin Ruan , Wei Wang
IPC分类号： G01N33/00 , G01N21/65
CPC分类号： G01N33/182 , G01N21/658 , Y10T436/153333 , Y10T436/173076 , Y10T436/19 , Y10T436/193333
摘要： This invention relates to the development of a new Raman enhancing reagent and a surface-enhanced Raman scattering (SERS) method for rapid and ultra-sensitive detection and identification of perchlorate (ClO4−) and other anions such as technetium (TcO4−), uranium and nitrate in environmental samples. The method involves the synthesis of controlled gold nanoparticles which are modified with amine functional groups such as 2-(dimethylamino)ethanethiol and N,N,N-trimethylaminethiol. These functionalized Au nanoparticles were found to be reactive with perchlorate and other anions and can be used to detect these anions by Raman spectroscopy at ultra low concentrations in complex environmental matrices. This invention overcomes the limitations of currently-available analytical techniques by offering an inexpensive, rapid, ultra-sensitive, and real-time identification and detection of perchlorate and other anions. The technique is not only sensitive but also highly specific because of the unique Raman vibrational bands of perchlorate and other anions.
摘要翻译：本发明涉及新型拉曼增强试剂和表面增强拉曼散射（SERS）方法的开发，用于快速和超灵敏检测和鉴定高氯酸盐（ClO4-）和其他阴离子如锝（TcO4-），铀和硝酸盐在环境样品中。该方法涉及用胺官能团如2-（二甲基氨基）乙硫醇和N，N，N-三甲基氨基硫醇修饰的受控金纳米颗粒的合成。发现这些官能化的Au纳米颗粒与高氯酸盐和其它阴离子反应，可用于通过拉曼光谱法在复杂环境基质中以超低浓度检测这些阴离子。本发明通过提供廉价，快速，超灵敏和实时鉴定和检测高氯酸盐和其他阴离子来克服当前可用的分析技术的局限性。由于高氯酸盐和其他阴离子的独特的拉曼振动带，该技术不仅敏感，而且具有高度的特异性。

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