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1. 发明申请

US20190169585A1 NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF 审中-公开
公开(公告)号：US20190169585A1
公开(公告)日：2019-06-06
申请号：US16275582
申请日：2019-02-14
申请人： DANISCO US INC.
发明人： Benjamin Bower , Mark Emptage , William D. Hitz , Megan Yee Hsi , Thijs Kaper , Bradley R. Kelemen , Steven Kim , Suzanne E. Lantz , Edmund A. Larenas , Colin Mitchinson , Keith Dumont Wing
IPC分类号： C12N9/24 , C12N9/20 , C12P19/00 , C12P19/14 , C12N9/42 , C12P19/02 , C12N9/16 , C12N9/08 , C12N9/04
摘要： The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.

2. 发明授权

US09523087B2 Cellulase variants with improved expression, activity and stability, and use thereof 有权
标题翻译：具有改善的表达，活性和稳定性的纤维素酶变体及其用途
公开(公告)号：US09523087B2
公开(公告)日：2016-12-20
申请号：US14189943
申请日：2014-02-25
申请人： Danisco US Inc.
发明人： Wolfgang Aehle , Richard R. Bott , Benjamin S. Bower , Jonathan Caspi , David A. Estell , Frits Goedegebuur , Ronaldus Wilhelmus Joannes Hommes , Thijs Kaper , Bradley R. Kelemen , Slavko Kralj , Johannes Franciscus Thomas Van Lieshout , Igor Nikolaev , Sander Van Stigt Thans , Louise Wallace , Gudrun Vogtentanz , Mats Sandgren
IPC分类号： C12N9/42 , C12N9/52 , C07H21/04
CPC分类号： C12N9/2437 , C12Y302/01091 , Y02E50/17
摘要： The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
摘要翻译：本公开涉及纤维素酶变体。特别地，本公开涉及具有改善的表达，活性和/或稳定性的纤维素酶变体。还描述了编码纤维素酶变体的核酸，包含纤维素酶变体的组合物及其使用方法。

3. 发明申请

US20210147890A1 COMPOSITION AND METHOD FOR DETERMINING THE AMOUNT OF GLUCOSE DERIVABLE FROM CELLULOSIC COMPONENTS OF FEEDSTOCK 有权
公开(公告)号：US20210147890A1
公开(公告)日：2021-05-20
申请号：US16623916
申请日：2018-07-02
申请人： DANISCO US INC.
发明人： Bradley R. Kelemen
IPC分类号： C12P19/02 , C12N9/42 , C12P19/14 , C12P7/10
摘要： Described are compositions and methods relating to the measurement of glucose derivable from the cellulosic components of a feedstock. The compositions and methods are particularly useful for ensuring that biofuel producers comply with the Renewable Fuel Standard while maximizing the value of the biofuel they produce.

4. 发明授权

US10190108B2 Method for reducing viscosity in saccharification process 有权
公开(公告)号：US10190108B2
公开(公告)日：2019-01-29
申请号：US14819989
申请日：2015-08-06
申请人： Danisco US Inc.
发明人： Colin Mitchinson , Mian Li , Bradley R. Kelemen , Suzanne E. Lantz , Keith D. Wing , William D. Hitz
IPC分类号： C12N9/42 , C12P19/02 , C12P19/14
摘要： The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.

5. 发明申请

US20190153493A1 METHOD FOR IMPROVING YIELD OF CELLULOSE CONVERSION PROCESSES 审中-公开
公开(公告)号：US20190153493A1
公开(公告)日：2019-05-23
申请号：US16259221
申请日：2019-01-28
申请人： DANISCO US INC
发明人： Bradley R. Kelemen , Colin MITCHINSON , Edmund A. LARENAS
IPC分类号： C12P19/14 , C12P19/12 , C12P19/02
摘要： The present teachings provide methods of converting cellulosic materials to soluble sugars. Methods for increasing the yield of glucose from the enzymatic saccharification of cellulosic materials is also provided. The present teachings further provide methods of increasing the yield of cellobiose from the enzymatic saccharification of cellulosic materials.

6. 发明授权

US09938551B2 Variants of cellobiohydrolases 有权
公开(公告)号：US09938551B2
公开(公告)日：2018-04-10
申请号：US14650285
申请日：2013-12-10
申请人： Danisco US Inc.
发明人： Richard R. Bott , Maria Foukaraki , Ronaldus Wilhelmus Hommes , Thijs Kaper , Bradley R. Kelemen , Slavko Kralj , Igor Nikolaev , Mats Sandgren , Johannes Franciscus Thomas Van Lieshout , Sander Van Stigt Thans
IPC分类号： C12P19/14 , C12P19/02 , C12N9/42
CPC分类号： C12P19/14 , C12N9/2434 , C12N9/2437 , C12P19/02 , C12Y302/01091
摘要： Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

7. 发明授权

US09695407B2 Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials 有权
公开(公告)号：US09695407B2
公开(公告)日：2017-07-04
申请号：US14662932
申请日：2015-03-19
申请人： Danisco US Inc.
发明人： Luis Cascao-Pereira , Thijs Kaper , Bradley R. Kelemen , Amy D. Liu
IPC分类号： C12N9/14 , C12N9/42 , C12P19/14 , C12P19/02
CPC分类号： C12N9/2437 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.

8. 发明申请

US20140085998A1 COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 审中-公开
标题翻译：包含各种保护素和/或细菌体的组合物及其用途
公开(公告)号：US20140085998A1
公开(公告)日：2014-03-27
申请号：US13974988
申请日：2013-08-23
申请人： Danisco US Inc.
发明人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward II , Gregory M. Whited
IPC分类号： C09D11/02 , G11C7/00 , G11B7/242
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译：本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定混合物。蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材和塑料材料，其中所述固体材料沉积在所述基底上。本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。

9. 发明授权

US12084728B2 Increasing severity acid hydrolysis assays for determining the amount of glucose derivable from cellulose in feedstocks 有权
公开(公告)号：US12084728B2
公开(公告)日：2024-09-10
申请号：US17286699
申请日：2019-10-14
申请人： DANISCO US INC , ARCHER DANIELS MIDLAND COMPANY
发明人： Kristin Y. Nose Crotty , Bradley R. Kelemen , Colin Fritz , Erin Rockafellow , Jacob Summerlott
IPC分类号： C12P19/02 , C12P19/14 , C13K1/02 , C13K1/06
CPC分类号： C13K1/02 , C12P19/02 , C12P19/14 , C13K1/06
摘要： Described are compositions and methods relating to the measurement of glucose derivable from the cellulosic components of a feedstock. The compositions and methods are particularly useful for ensuring that biofuel producers comply with the Renewable Fuel Standard while maximizing the value of the biofuel they produce.

10. 发明授权

US10081802B2 Variant Enzymes 有权
公开(公告)号：US10081802B2
公开(公告)日：2018-09-25
申请号：US14909007
申请日：2014-07-24
申请人： DANISCO US INC.
发明人： Maria Foukaraki , Ronaldus Wilhelmus Hommes , Thijs Kaper , Bradley R. Kelemen , Slavko Kralj , Suzanne E. Lantz , Igor Nikolaev , Wilhelmus Van Der Kley , Johannes Franciscus Thomas Van Lieshout , Sander Van Stigt Thans
IPC分类号： C12N9/42 , C12P19/14 , C12P19/02 , C12N9/24
摘要： Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

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