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1. 发明授权

US07862606B2 Stents made of a material with short elongation at rupture 有权
标题翻译：由断裂伸长率短的材料制成的支架
公开(公告)号：US07862606B2
公开(公告)日：2011-01-04
申请号：US10557876
申请日：2004-04-15
申请人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch , Baerbel Becher
发明人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch , Baerbel Becher
IPC分类号： A61F2/82
CPC分类号： A61L31/148 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2210/0004 , A61F2230/0013 , A61L31/14
摘要： The invention relates to stents made of a material with an elongation at rupture of 30% or less and with a tubular base body which entirely or in parts comprises structural segments which are interconnected in longitudinal direction of the stents by means of transverse connectors and in which the structural segments comprise a zigzagging or undulating structure of a brace which is wrapped around the longitudinal axis of the stent. Due to the mechanical properties of the materials used, adaptation of the stent design is required. This is achieved in that in a turning region of the zigzagging or undulating structure the brace comprises a straight bending section aligned in circumferential direction.
摘要翻译：本发明涉及由断裂伸长率为30％以下的材料制成的支架，并且管状基体全部或部分包括通过横向连接件在支架的纵向互相连接的结构段，其中结构段包括围绕支架的纵向轴线缠绕的支架的锯齿形或起伏结构。由于使用的材料的机械性能，需要适应支架设计。这是通过在曲折或起伏结构的转动区域中实现的，支架包括沿圆周方向对准的直的弯曲部分。

2. 发明申请

US20070142899A1 Stents made of a material with short elongation at rupture 有权
标题翻译：由断裂伸长率短的材料制成的支架
公开(公告)号：US20070142899A1
公开(公告)日：2007-06-21
申请号：US10557876
申请日：2004-04-15
申请人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch , Baerbel Becher
发明人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch , Baerbel Becher
IPC分类号： A61F2/90
CPC分类号： A61L31/148 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2210/0004 , A61F2230/0013 , A61L31/14
摘要： The invention relates to stents made of a material with an elongation at rupture of 30% or less and with a tubular base body which entirely or in parts comprises structural segments which are interconnected in longitudinal direction of the stents by means of transverse connectors and in which the structural segments comprise a zigzagging or undulating structure of a brace which is wrapped around the longitudinal axis of the stent. Due to the mechanical properties of the materials used, adaptation of the stent design is required. This is achieved in that in a turning region of the zigzagging or undulating structure the brace comprises a straight bending section aligned in circumferential direction.
摘要翻译：本发明涉及由断裂伸长率为30％以下的材料制成的支架，并且管状基体全部或部分包括通过横向连接件在支架的纵向互相连接的结构段，其中结构段包括围绕支架的纵向轴线缠绕的支架的锯齿形或起伏结构。由于使用的材料的机械性能，需要适应支架设计。这是通过在曲折或起伏结构的转动区域中实现的，支架包括沿圆周方向对准的直的弯曲部分。

3. 发明授权

US07004968B2 Stent 有权
标题翻译：支架
公开(公告)号：US07004968B2
公开(公告)日：2006-02-28
申请号：US10739905
申请日：2003-12-17
申请人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch
发明人： Daniel Lootz , Karsten Koop , Frank Bakczewitz , Martin Kiekbusch
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91583 , A61F2230/0054 , A61F2250/0039
摘要： The invention concerns a stent comprising a longitudinal axis (12) and a peripheral wall (14) which is formed at least over a part of the length of the stent (10) by a lattice-like carrier structure (24) which is open at two ends. The carrier structure includes at least one bar (16) extending helically around the longitudinal axis in such a way as to provide a helical primary shape (26) for the peripherally extending bar with more than one helical turn. Besides the helical primary shape (26) the bar has a zigzag-like or meander-shaped secondary shape (30) with reversal points and associated reversal portions (32), between which extend bar portions (34) of the peripherally extending bar with an extension component in the longitudinal direction of the stent. The carrier structure further includes connecting bars (40) which respectively bridge over a helical turn of the helical primary structure and which at their two longitudinal ends attach to the bar portions (34) of the helical primary shape between two respective adjacent reversal points.
摘要翻译：本发明涉及一种支架，其包括纵向轴线（12）和周壁（14），所述纵向轴线（12）和周壁（14）通过格子状载体结构（24）形成在支架（10）的至少一部分长度上，两端载体结构包括至少一个杆（16），其沿着纵向轴线螺旋地延伸，以便为具有多于一个螺旋转的外围延伸的杆提供螺旋形的主要形状（26）。除了螺旋形的主要形状（26）之外，杆具有锯齿状或曲折形的次级形状（30），其具有反转点和相关联的反转部分（32），在其之间延伸周边延伸杆的杆部分（34）延伸部件在支架的纵向上。载体结构还包括连接杆（40），其分别跨过螺旋形一次结构的螺旋形转弯并且其两个纵向端部连接到螺旋形初级形状的杆部分（34）在两个相应的相邻反向点之间。

4. 发明申请

US20090164002A1 IMPLANT WITH A BASE BODY OF A BIOCORRODIBLE ALLOY 审中-公开
标题翻译：植物与生物可追溯合金的基体
公开(公告)号：US20090164002A1
公开(公告)日：2009-06-25
申请号：US12339965
申请日：2008-12-19
申请人： Baerbel Becher , Carsten Momma , Daniel Lootz , Antje Quade , Andreas Ohl , Karsten Schroeder
发明人： Baerbel Becher , Carsten Momma , Daniel Lootz , Antje Quade , Andreas Ohl , Karsten Schroeder
IPC分类号： A61F2/06 , A61B19/00
CPC分类号： A61L31/022 , A61L31/082 , A61L31/148
摘要： An implant having a base body, comprised either entirely or in part of a biocorrodible metallic material wherein at least the parts of the base body having the biocorrodible metallic material are at least partially covered with a coating of a crosslinked CFx layer with an F/C ratio in the range of 0.5 to 1.5.
摘要翻译：具有基体的植入体，其全部或部分由生物可腐蚀的金属材料组成，其中至少部分具有生物可腐蚀金属材料的基体部分至少部分地覆盖有具有F / C的交联CFx层的涂层比例在0.5至1.5的范围内。

5. 发明申请

US20100145432A1 IMPLANT AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：植入物及其制造方法
公开(公告)号：US20100145432A1
公开(公告)日：2010-06-10
申请号：US12630407
申请日：2009-12-03
申请人： Ullrich Bayer , Baerbel Becher , Bernd Block , Daniel Lootz
发明人： Ullrich Bayer , Baerbel Becher , Bernd Block , Daniel Lootz
IPC分类号： A61F2/82 , B05D3/10
CPC分类号： A61L31/022 , A61L31/10 , A61L31/148 , A61L2420/08 , C23C22/34 , C23C22/60 , C08L65/04
摘要： The present invention describes a method for producing an implant, in particular an intraluminal endoprosthesis, wherein the base material of the body (5) of the implant has biodegradable metallic material, preferably Mg or an Mg alloy. The method comprises the following steps: a. Provide the body (5) of the implant, b. Apply a first layer (10), which contains Ca ions and P ions, to at least a part of the surface of the body (5) and c. Apply a second layer (20), which is at least partially permeable for Ca ions and P ions, such that this at least largely covers the first layer (10). Furthermore, a corresponding implant is described, in which the degradation behavior can be controlled through the production according to the invention.
摘要翻译：本发明描述了用于制造植入物，特别是管腔内假体的方法，其中植入体的主体（5）的基底材料具有可生物降解的金属材料，优选Mg或Mg合金。该方法包括以下步骤：a。提供植入物的体（5），b。将包含Ca离子和P离子的第一层（10）施加到体（5）的至少一部分表面，c。施加第二层（20），其对于Ca离子和P离子至少部分可渗透，使得其至少大部分覆盖第一层（10）。此外，描述了相应的植入物，其中可以通过根据本发明的生产来控制降解行为。

6. 发明授权

US06796998B2 Stent 有权
标题翻译：支架
公开(公告)号：US06796998B2
公开(公告)日：2004-09-28
申请号：US09974770
申请日：2001-10-09
申请人： Max Schaldach , Daniel Lootz , Karsten Koop , Curt Kranz
发明人： Max Schaldach , Daniel Lootz , Karsten Koop , Curt Kranz
IPC分类号： A61F206
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2230/0054
摘要： A stent, in particular a coronary stent, for expansion from a first condition into an expanded second condition in which it holds a vessel in an expanded state, comprising a tubular body whose peripheral surface (1) is formed by a number of annular support portions (2, 2.1, 2.2, 2.3) comprising bar elements (3, 3.1, 3.2, 3.3) which are connected in the longitudinal direction of the stent by way of connecting bars (4, 4.1, 4.2), wherein the bar elements (3.1) of at least a first support portion (2.1) and a second support portion (2.2) in adjacent relationship in a first direction (6.1) extend in a meander configuration in the peripheral direction of the stent and the connecting bars (4, 4.1, 4.2) to the second support portion (2.2) engage in the region of the turning points (5, 5.2, 5.3) of the first support portion (2.1), which turning points face in the first direction (6.1), wherein at least two adjacent connecting bars (4.1, 4.2) engage respectively in the region of a turning point (5.1) of the second support portion (2.2), which turning point projects in a second direction (6.2) in opposite relationship to the first direction (6.1).
摘要翻译：一种支架，特别是冠状支架，用于从第一状态膨胀到膨胀的第二状态，其中容纳膨胀状态的容器，包括管状体，其外周表面（1）由多个环形支撑部分（2,2.1,2.2,2.3），其包括通过连接杆（4,4.1,4.2）在所述支架的纵向方向上连接的杆元件（3,3.1,3.2,3.3），其中所述杆元件（3.1,3.2,3.3）至少第一支撑部分（2.1）和第二支撑部分（2.2）在第一方向（6.1）的相邻关系中沿着支架的圆周方向以曲折形状延伸，并且连接杆（4,4.1，第二支撑部分（2.2）的第二支撑部分（2.2）接合在第一支撑部分（2.1）的转折点（5,5.2,5.3）的区域中，该转动点面向第一方向（6.1），其中至少两个相邻的连接杆（4.1,4.2）分别接合在转向点的区域中（2.2）的第二方向（6.2）的第二方向（6.2）突出的第二支撑部分（2.2）。

7. 发明授权

US08157859B2 Stent made of nitinol having improved axial bending stiffness and associated production method 有权
标题翻译：具有改善的轴向弯曲刚度和相关生产方法的由镍钛诺制成的支架
公开(公告)号：US08157859B2
公开(公告)日：2012-04-17
申请号：US12256004
申请日：2008-10-22
申请人： Daniel Lootz , Bernd Block
发明人： Daniel Lootz , Bernd Block
IPC分类号： A61F2/82
CPC分类号： A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2210/0023 , A61F2250/0018 , A61F2250/0042
摘要： A stent made of nitinol having improved axial or radial stiffness, the stent having a support structure which comprises peripheral struts around the circumference, wherein the peripheral struts are linked to one another in the axial direction via connection struts. The support structure may assume a first compressed state and a second expanded state. The nitinol is in the support structure in a martensitic microstructure in the compressed state and largely in an austenitic microstructure in the second expanded state. One or more support structure sections, however, are entirely or partially in a martensitic microstructure in the second expanded state.
摘要翻译：由炔诺醇制成的具有改进的轴向或径向刚度的支架，所述支架具有支撑结构，所述支撑结构包括围绕所述圆周的外围支柱，其中所述外围支柱通过连接支柱在轴向方向上彼此连接。支撑结构可以呈现第一压缩状态和第二扩展状态。镍钛诺在处于压缩状态的马氏体组织的支撑结构中，并且在第二膨胀状态下处于奥氏体组织中。然而，一个或多个支撑结构部分在第二膨胀状态下完全或部分地处于马氏体组织中。

8. 发明申请

US20100010615A1 INSERTION SYSTEM FOR A MEDICAL DEVICE HAVING A SHEATH AND SHEATH FOR AN INSERTION SYSTEM FOR A MEDICAL DEVICE 审中-公开
标题翻译：具有用于医疗装置的插入系统的护理和护理的医疗装置的插入系统
公开(公告)号：US20100010615A1
公开(公告)日：2010-01-14
申请号：US12495927
申请日：2009-07-01
申请人： Eugen Hofmann , Daniel Lootz
发明人： Eugen Hofmann , Daniel Lootz
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/88 , A61F2002/30024 , A61F2250/0021
摘要： An insertion system (100) for a medical device (10), which is situated in an outer sheath (20) upon insertion, the outer sheath (20) at least regionally encompassing an inner shaft. The outer sheath (20) at least regionally has, at least on its inner side (29) facing toward the medical device (10), a structure (22, 32) which is complementary with an external-peripheral segmented structure (12) of the medical device (10) like a bolt-nut connection.
摘要翻译：一种用于医疗装置（10）的插入系统（100），其在插入时位于外护套（20）中，所述外护套（20）至少在区域上包围内轴。至少在至少在其内侧（29）面向医疗装置（10）的区域上，外护套（20）至少具有与外周分段结构（12）互补的结构（22,32）该医疗装置（10）类似螺栓 - 螺母连接。

9. 发明申请

US20100161030A1 Device and Method for Producing Same 有权
标题翻译：装置及其制作方法
公开(公告)号：US20100161030A1
公开(公告)日：2010-06-24
申请号：US12576102
申请日：2009-10-08
申请人： Ullrich Bayer , Daniel Lootz
发明人： Ullrich Bayer , Daniel Lootz
IPC分类号： A61F2/06 , B32B38/00 , B23K15/00 , B23K26/00 , B21J15/00 , B30B13/00
CPC分类号： A61L31/022 , A61L31/10 , A61L31/148 , A61L31/18 , A61L2420/02 , C25D11/024 , C25D11/026 , C25D11/16 , C25D11/26 , Y10T29/49943
摘要： The invention relates to a device, in particular for medical use as an endoprosthesis, preferably as an intraluminal endoprosthesis, having a base body (1, 1′), comprising at least partially a metallic material, and having a function element (3, 3′) that is attached to the base body and has a different metallic material composition in comparison with the material of the base body (1, 1′) in at least a portion of its volume, preferably having at least partially radiopaque and/or radiologically opaque material. To reduce direct metal contact between the base body (1,1′) and the function element (3, 3′) in the area where the base body (1, 1′) and the function element (3, 3′) are adjacent to one another, a first layer (5, 5′) is applied to and/or introduced into the borderline area (9, 9′) between the base body (1, 1′) and the function element (3, 3′), extending to the surface, such that said first layer is produced by plasma-chemical treatment in an aqueous solution containing phosphate ions, or comprises magnesium stearate. Furthermore, a method for producing such a device is proposed.
摘要翻译：本发明涉及一种装置，特别是作为内用假体的医疗用途，优选为腔内内用假体，具有基体（1,1'），其包括至少部分金属材料，并具有功能元件（3,3） '），其在基体的至少一部分体积中与基体（1,1'）的材料相比具有不同的金属材料组成，优选具有至少部分不透射线和/或放射学不透明材料。为了减少在基体（1,1'）和功能元件（3,3'）相邻的区域中基体（1,1'）与功能元件（3,3'）之间的直接金属接触第一层（5,5'）施加到基体（1'）和功能元件（3,3'）之间的边界区域（9,9'）和/或其中，延伸到表面，使得所述第一层通过在含有磷酸根离子的水溶液中进行等离子体化学处理而制备，或包含硬脂酸镁。此外，提出了一种用于制造这种装置的方法。

10. 发明申请

US20050096722A1 Stent implantation system and vessel support 审中-公开
标题翻译：支架植入系统和血管支架
公开(公告)号：US20050096722A1
公开(公告)日：2005-05-05
申请号：US10892528
申请日：2004-07-14
申请人： Daniel Lootz , Stephane Delaloye , Curt Kranz , Goran Lukic
发明人： Daniel Lootz , Stephane Delaloye , Curt Kranz , Goran Lukic
IPC分类号： A61F2/91 , A61F2/915 , A61F2/958 , A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2/958 , A61F2002/91533 , A61F2230/0013
摘要： A stent implantation system comprising a catheter and an expandable vessel support which is releasable fixed in the region of the distal end thereof and which has a carrier structure which encloses a cavity open at its distal ends characterized in that the carrier structure of the vessel supports formed by at least two carrier rings which in their non-expanded condition are jointly fixed to the catheter and are not connected together otherwise.
摘要翻译：一种支架植入系统，其包括导管和可释放固定在其远端区域中的可扩张血管支撑件，并且其具有包围其远端处开口的腔的载体结构，其特征在于，所述血管支架的载体结构形成通过至少两个在其未膨胀状态下的载体环共同地固定到导管上并且不连接在一起。

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