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1. 发明授权

US06524247B2 Method and system for ultrasound imaging of a biopsy needle 有权
标题翻译：活检针超声成像的方法和系统
公开(公告)号：US06524247B2
公开(公告)日：2003-02-25
申请号：US09858221
申请日：2001-05-15
申请人： Danhua Zhao , Tommy Earl Cupples , Zengpin Yu
发明人： Danhua Zhao , Tommy Earl Cupples , Zengpin Yu
IPC分类号： A61B800
CPC分类号： A61B8/0841 , A61B8/0833 , A61B2017/3413
摘要： A method, system, computer program product, and user interface for real-time ultrasonic visualization enhancement of a biopsy needle are disclosed in which a wide range of needle positions with respect to the ultrasound probe axis and with respect to the imaged plane are accommodated. Ordinary frames are compounded with special purpose frames, the special purpose frames having transmit and receive parameters adapted to highlight reception of echoes from the biopsy needle. Preferably, an elevation beam width associated with the special purpose ultrasound frames is wider than an elevation beam width associated with the ordinary ultrasound frames. Preferably, the beams of the special purpose ultrasound frames are steered such that they are incident upon the biopsy needle at an increased angle as compared to the angle of incidence for ordinary ultrasound frames. A method for automatically and adaptively determining the depth and orientation of a biopsy needle is also described, whereby beam steering parameters, focus parameters, etc. may be automatically and adaptively computed. The user may optionally provide selected beam steering parameters to the ultrasound imaging system using a simple, intuitive user interface.
摘要翻译：公开了一种用于活检针的实时超声可视化增强的方法，系统，计算机程序产品和用户界面，其中适应相对于超声探针轴和相对于成像平面的宽范围的针位置。普通帧与专用帧相结合，专用帧具有适于突出从活检针接收回波的发射和接收参数。优选地，与专用超声波帧相关联的仰角波束宽度比与普通超声波帧相关联的仰角波束宽度宽。优选地，专用超声波框架的梁被转向，使得它们与普通超声波框架的入射角相比以更大的角度入射到活检针上。还描述了一种用于自动和自适应地确定活检针的深度和取向的方法，由此可以自动和自适应地计算光束转向参数，聚焦参数等。使用者可以使用简单直观的用户界面来选择性地向超声成像系统提供选择的波束操纵参数。

2. 发明申请

US20110098566A1 THICK-SLICE ULTRASOUND IMAGES DERIVED FROM ULTRASONIC SCANS OF A CHESTWARDLY-COMPRESSED BREAST OF A SUPINE PATIENT 有权
标题翻译：超声波超声波超声波扫描的厚度超大的超声波扫描仪
公开(公告)号：US20110098566A1
公开(公告)日：2011-04-28
申请号：US12890374
申请日：2010-09-24
申请人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/14 , G06T15/20
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

3. 发明授权

US08496586B2 Breast ultrasound examination including scanning through chestwardly compressing membrane and processing and displaying acquired ultrasound image information 有权
标题翻译：胸部超声检查包括通过胸膜压迫膜进行扫描，并处理和显示获取的超声图像信息
公开(公告)号：US08496586B2
公开(公告)日：2013-07-30
申请号：US12760382
申请日：2010-04-14
申请人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
发明人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
IPC分类号： A61B8/00
CPC分类号： A61B8/0825 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/469 , A61B8/483 , A61B8/5238 , A61B8/565
摘要： Navigation among breast ultrasound volumes derived from different volumetric ultrasonic scans of a same breast is described. On a display of a breast ultrasound workstation, a first image derived from a first ultrasonic volume is displayed. A user election of a source region of interest (ROI) in the first image is received. A destination ROI within a second ultrasonic volume is identified that at least roughly corresponds to a same locality of tissue in the breast as the source ROI. A second image derived from the second ultrasonic volume and including the destination ROI is displayed, the destination ROI being highlighted.
摘要翻译：描述从相同乳房的不同体积超声波扫描得到的乳房超声体积之间的导航。在乳房超声工作站的显示器上，显示从第一超声波体积得到的第一图像。接收用户选择第一图像中的感兴趣的源区域（ROI）。识别出在第二超声波体积内的目的地ROI至少大致对应于乳房中与源ROI相同的局部区域。显示从第二超声波体积导出并包括目的地ROI的第二图像，目的地ROI被突出显示。

4. 发明申请

US20100280375A1 Breast Ultrasound Examination Including Scanning Through Chestwardly Compressing Membrane And Processing And Displaying Acquired Ultrasound Image Information 有权
标题翻译：乳房超声检查包括通过胸部压缩膜扫描和处理和显示获得的超声图像信息
公开(公告)号：US20100280375A1
公开(公告)日：2010-11-04
申请号：US12760382
申请日：2010-04-14
申请人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
发明人： Wei Zhang , Jiayu Chen , Thomas P. Neff , Michael E. Reed , Jeanine M. Rader , Douglas G. Summers , Shih-Ping Wang , Tor C. Anderson , Zengpin Yu , Tommy Earl Cupples
IPC分类号： A61B8/14 , G06K9/62
CPC分类号： A61B8/0825 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/469 , A61B8/483 , A61B8/5238 , A61B8/565
摘要： Navigation among breast ultrasound volumes derived from different volumetric ultrasonic scans of a same breast is described. On a display of a breast ultrasound workstation, a first image derived from a first ultrasonic volume is displayed. A user election of a source region of interest (ROI) in the first image is received. A destination ROI within a second ultrasonic volume is identified that at least roughly corresponds to a same locality of tissue in the breast as the source ROI. A second image derived from the second ultrasonic volume and including the destination ROI is displayed, the destination ROI being highlighted.
摘要翻译：描述从相同乳房的不同体积超声波扫描得到的乳房超声体积之间的导航。在乳房超声工作站的显示器上，显示从第一超声波体积得到的第一图像。接收用户选择第一图像中的感兴趣的源区域（ROI）。识别出在第二超声波体积内的目的地ROI至少大致对应于乳房中与源ROI相同的局部区域。显示从第二超声波体积导出并包括目的地ROI的第二图像，目的地ROI被突出显示。

5. 发明授权

US07615008B2 Processing and displaying breast ultrasound information 有权
标题翻译：处理和显示乳房超声信息
公开(公告)号：US07615008B2
公开(公告)日：2009-11-10
申请号：US10997293
申请日：2004-11-23
申请人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/00
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

6. 发明授权

US08162833B2 Thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast of a supine patient 有权
标题翻译：来自仰卧患者胸部压缩乳房超声扫描的厚片超声图像
公开(公告)号：US08162833B2
公开(公告)日：2012-04-24
申请号：US12890374
申请日：2010-09-24
申请人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/00
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

7. 发明授权

US07828733B2 Coronal and axial thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast 有权
标题翻译：冠状和轴向厚片超声图像来自胸部压缩乳房的超声波扫描
公开(公告)号：US07828733B2
公开(公告)日：2010-11-09
申请号：US12545201
申请日：2009-08-21
申请人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/00
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译：描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。还描述了厚片图像内和书签中心和CAD标记为中心的导航。

8. 发明授权

US06524252B1 Method and system for generating ultrasound frames with decorrelated speckle patterns and generating a compound ultrasound image therefrom 失效
标题翻译：用于产生具有解相关散斑图案的超声波帧并从其产生复合超声图像的方法和系统
公开(公告)号：US06524252B1
公开(公告)日：2003-02-25
申请号：US09721889
申请日：2000-11-24
申请人： Zengpin Yu , Danhua Zhao , Shengtz Lin , Feng Yin
发明人： Zengpin Yu , Danhua Zhao , Shengtz Lin , Feng Yin
IPC分类号： A61B800
CPC分类号： G01S7/52074 , G01S7/52046
摘要： An ultrasound system that generates compound images from component frames having decorrelated speckle patterns. Successive sets of distinct, speckle-affecting parameters are used to generate successive component frames for compounding, and are selected such that the successive component frames have decorrelated speckle patterns. The speckle-affecting parameters that are changed from frame to frame may be selected from a wide variety of parameters, including transmit beamformer parameters, receive beamformer parameters, and demodulator parameters. According to a preferred embodiment, the successive sets of speckle-affecting parameters differ from each other by at least two speckle-affecting parameters. According to another preferred embodiment, the amount by which each of the multiple speckle-affecting parameters is changed is less than a decorrelation threshold for that parameter, that is, by less that the amount that speckle-affecting parameter alone would be required to change in order to yield decorrelated speckle patterns if no other parameters were changed. When more speckle-affecting parameters are changed, each speckle-affecting parameter can be changed by an amount less than its decorrelation threshold, and yet decorrelated speckle patterns can still be obtained. Moreover, because two different types of speckle-affecting parameters tend to alter the spatial resolution of the component frames in different ways, the spatial resolution of the compounded image can be better as compared to the scenario in which only one speckle-affecting parameter is altered by its decorrelation threshold.
摘要翻译：超声系统，其从具有去相关散斑图案的分量帧生成复合图像。连续的不同的，具有斑点影响的参数被用于生成用于复合的连续分量帧，并且被选择成使得连续分量帧具有去相关的散斑图案。从帧到帧改变的斑点影响参数可以从各种参数中选择，包括发射波束形成器参数，接收波束形成器参数和解调器参数。根据优选实施例，连续的斑点影响参数组彼此之间至少有两个斑点影响参数不同。根据另一个优选实施例，多个斑点影响参数中的每一个改变的量小于该参数的去相关阈值，即，少于仅需要改变斑点影响参数的量如果没有其他参数被改变，则产生去相关的斑点图案。当更多的斑点影响参数改变时，每个斑点影响参数可以改变一个小于其去相关阈值的量，然而仍然可以获得去相关的斑点图案。此外，由于两种不同类型的斑点影响参数倾向于以不同的方式改变分量帧的空间分辨率，所以与仅改变一个斑点影响参数的情况相比，复合图像的空间分辨率可以更好通过其去相关阈值。

9. 发明授权

US08317702B2 Full-field breast ultrasound system and architecture 有权
标题翻译：全场乳房超声系统和体系结构
公开(公告)号：US08317702B2
公开(公告)日：2012-11-27
申请号：US10560200
申请日：2004-06-18
申请人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
发明人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
IPC分类号： A61B8/00
CPC分类号： A61B8/4477 , A61B8/0825 , A61B8/4281 , A61B8/4405 , A61B8/5238 , Y10T29/49005
摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).
摘要翻译：描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能，诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。快速创建双功能超声系统（200）。

10. 发明申请

US20100331699A1 Full-field breast ultrasound system and architecture 有权
标题翻译：全场乳房超声系统和体系结构
公开(公告)号：US20100331699A1
公开(公告)日：2010-12-30
申请号：US10560200
申请日：2004-06-18
申请人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
发明人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
IPC分类号： A61B8/14
CPC分类号： A61B8/4477 , A61B8/0825 , A61B8/4281 , A61B8/4405 , A61B8/5238 , Y10T29/49005
摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).
摘要翻译：描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能，诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。快速创建双功能超声系统（200）。

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