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1. 发明授权

US08096525B2 Swabbable needle-free injection port valve system with zero fluid displacement 失效
标题翻译：具有零流体排量的可滑动无针注射口阀系统
公开(公告)号：US08096525B2
公开(公告)日：2012-01-17
申请号：US12428678
申请日：2009-04-23
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： F16K51/00
CPC分类号： F16K51/00 , A61M39/26 , A61M2039/267 , Y10S604/905
摘要： An improved needle-free intravenous injection port assembly is disclosed. Embodiments include a boot valve with a helical surface, a boot valve and septum which mate with mechanical interference, a spike with a rough outer surface coated with a lubricant, a septum having a shoulder and a single continuous swabbable surface, a septum and a boot valve which are pre-punctured, a septum with a frustroconical extension and a combination single piece septum and boot valve. The injection port assembly provides zero fluid displacement during coupling and uncoupling.
摘要翻译：公开了一种改进的无针静脉注射口组件。实施例包括具有螺旋表面的启动阀，与机械干扰配合的护罩阀和隔膜，具有涂覆有润滑剂的粗糙外表面的钉，具有肩部和单个连续可擦拭表面的隔膜，隔膜和靴子预先穿刺的阀门，具有截头锥形延伸部的隔膜和单件隔膜和开启阀组合。注入口组件在联接和解耦期间提供零流体位移。

2. 发明授权

US5871471A Disposable value assembly for reusable surgical trocar 失效
标题翻译：可重复使用的手术套管针的一次性价值装配
公开(公告)号：US5871471A
公开(公告)日：1999-02-16
申请号：US458135
申请日：1995-06-02
申请人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
发明人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
IPC分类号： A61B17/00 , A61B17/34 , A61M39/06 , A61M5/178
CPC分类号： A61M39/0606 , A61B17/3496 , A61B17/3498 , A61B17/3417 , A61B17/3474 , A61B2017/0023 , A61B2017/0046 , A61B2017/00477 , A61B2017/3464 , A61M2039/0626 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M39/06 , Y10T137/7885
摘要： A surgical trocar assembly includes a disposable valve assembly, a cannula assembly, and a trocar with a handle. The cannula assembly includes a cannula base having a valve assembly coupling device at its proximal end, and a cannula extending from its distal end. The disposable valve assembly has a coupling device for removably coupling it with the cannula base. The valve assembly also includes a valve body with a fluid passage communicating with the hollow cannula when it is coupled to the cannula base. A slit or flapper valve and a universal washer are mounted within the valve body and allow the insertion of the trocar or other endoscopic instruments therethrough while providing a fluid sealing of the fluid passage. The valve assembly may be provided with a side port which optionally contains an automatic valve actuated by a luer coupling. Several different valve assembly-cannula base couplings are disclosed as well as several different types of trocars.
摘要翻译：手术套管针组件包括一次性阀组件，套管组件和带手柄的套管针。套管组件包括在其近端具有阀组件联接装置的套管基座和从其远端延伸的套管。一次性阀组件具有用于将其与插管基座可拆卸地联接的联接装置。阀组件还包括阀体，当其连接到套管基座时，具有与中空套管连通的流体通道。狭缝或挡板阀和通用垫圈安装在阀体内，并允许套管针或其他内窥镜器械插入，同时提供流体通道的流体密封。阀组件可以设置有侧端口，其可选地包含由鲁尔耦合器致动的自动阀。公开了几种不同的阀组件 - 套管基座联接器以及几种不同类型的套管针。

3. 发明授权

US6158458A Medical intravenous administration line connectors having a luer or pressure activated valve 有权
标题翻译：具有鲁尔或压力激活阀的医疗静脉内管线连接器
公开(公告)号：US6158458A
公开(公告)日：2000-12-12
申请号：US344403
申请日：1999-06-24
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： F16L37/42 , A61J1/00 , A61J1/20 , A61M5/162 , A61M39/24 , A61M39/26 , F16L37/28 , F16L41/03 , F16L41/16 , A61M5/00 , F16K15/14
CPC分类号： A61J1/2096 , A61M39/24 , A61M39/26 , F16L41/03 , F16L41/16 , A61J1/201 , A61J1/2037 , A61M2039/242 , A61M2039/2473 , A61M2039/2486 , A61M5/16813 , Y10S137/903 , Y10T137/7856 , Y10T137/7879
摘要： Medical intravenous administration connectors according to a first embodiment include a first coupling member having a female luer, a valve member having a substantially rigid stem and a substantially resilient body with a sealing surface, and a second coupling member having a fluid coupling extending from one end and an internal valve member support. The coupling members are structured to couple to each other with the valve member being biased to a closed position. When assembled, the valve stem extends into the female luer, and the valve body biases the sealing surface against an annular ring in the first coupling member thereby blocking fluid communication. Vanes are provided in the second coupling member on which the resilient body of the valve sits, with the vanes acting as a centering mechanism for the valve. The valve is opened for fluid flow through the assembly by coupling a male luer to the female luer of the assembly. According to a second embodiment, the valve stem is replaced by a dome-like protrusion on the resilient valve body. The valve of the second embodiment is opened by applying fluid under pressure through the female luer. According to a third embodiment, the valve is partially rigid and partially resilient. All embodiments are easy to prime, limit priming volume, and are arranged without dead-spaces in which blood can be trapped.
摘要翻译：根据第一实施例的医疗静脉内给药连接器包括具有阴路厄的第一联接构件，具有基本上刚性的杆的阀构件和具有密封表面的基本上弹性的主体，以及具有从一端延伸的流体联接件的第二联接构件和内部阀构件支撑件。联接构件被构造成彼此联接，阀构件被偏压到关闭位置。当组装时，阀杆延伸到母路厄尔中，并且阀体将密封表面抵靠第一联接构件中的环形圈偏压，从而阻止流体连通。叶片设置在阀的弹性体所在的第二联接构件中，叶片用作阀的定心机构。打开阀门，使液体通过组件通过将公路厄尔连接到组件的母路厄尔而流动。根据第二实施例，阀杆由弹性阀体上的圆顶状突起代替。第二实施例的阀通过在压力下施加流体通过母路厄尔打开。根据第三实施例，阀是部分刚性的并且部分弹性。所有实施方案易于起始，限制起泡体积，并且布置成没有血液可被捕获的死空间。

4. 发明授权

US06099505A Valve assembly with automatic valve 有权
标题翻译：阀组件带自动阀
公开(公告)号：US06099505A
公开(公告)日：2000-08-08
申请号：US146504
申请日：1998-09-02
申请人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
发明人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
IPC分类号： A61B17/00 , A61B17/34 , A61M39/06 , A61M5/178
CPC分类号： A61M39/0606 , A61B17/3496 , A61B17/3498 , A61B17/3417 , A61B17/3474 , A61B2017/0023 , A61B2017/0046 , A61B2017/00477 , A61B2017/3464 , A61M2039/0626 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M39/06
摘要： A surgical trocar assembly includes a disposable valve assembly, a cannula assembly, and a trocar with a handle. The cannula assembly includes a cannula base having a valve assembly coupling device at its proximal end, and a cannula extending from its distal end. The disposable valve assembly has a coupling device for removably coupling it with the cannula base. The valve assembly also includes a valve body with a fluid passage communicating with the hollow cannula when it is coupled to the cannula base. A slit or flapper valve and a universal washer are mounted within the valve body and allow the insertion of the trocar or other endoscopic instruments therethrough while providing a fluid sealing of the fluid passage. The valve assembly may be provided with a side port which optionally contains an automatic valve actuated by a luer coupling. Several different valve assembly-cannula base couplings are disclosed as well as several different types of trocars.
摘要翻译：手术套管针组件包括一次性阀组件，套管组件和带手柄的套管针。套管组件包括在其近端具有阀组件联接装置的套管基座和从其远端延伸的套管。一次性阀组件具有用于将其与插管基座可拆卸地联接的联接装置。阀组件还包括阀体，当其连接到套管基座时，具有与中空套管连通的流体通道。狭缝或挡板阀和通用垫圈安装在阀体内，并允许套管针或其他内窥镜器械插入，同时提供流体通道的流体密封。阀组件可以设置有侧端口，其可选地包含由鲁尔耦合器致动的自动阀。公开了几种不同的阀组件 - 套管基座联接器以及几种不同类型的套管针。

5. 发明申请

US20090200504A1 SWABBABLE NEEDLE-FREE INJECTION PORT VALVE SYSTEM WITH ZERO FLUID DISPLACEMENT 失效
标题翻译：具有零流体位移的可开关的无针注入口阀系统
公开(公告)号：US20090200504A1
公开(公告)日：2009-08-13
申请号：US12428678
申请日：2009-04-23
申请人： Dana Wm. Ryan , David P. Gordon , James M. Kaiser , Frank A. Scarfone
发明人： Dana Wm. Ryan , David P. Gordon , James M. Kaiser , Frank A. Scarfone
IPC分类号： F16L37/28
CPC分类号： F16K51/00 , A61M39/26 , A61M2039/267 , Y10S604/905
摘要： An improved needle-free intravenous injection port assembly is disclosed. Embodiments include a boot valve with a helical surface, a boot valve and septum which mate with mechanical interference, a spike with a rough outer surface coated with a lubricant, a septum having a shoulder and a single continuous swabbable surface, a septum and a boot valve which are pre-punctured, a septum with a frustroconical extension and a combination single piece septum and boot valve. The injection port assembly provides zero fluid displacement during coupling and uncoupling.
摘要翻译：公开了一种改进的无针静脉注射口组件。实施例包括具有螺旋表面的启动阀，与机械干扰配合的护罩阀和隔膜，具有涂覆有润滑剂的粗糙外表面的钉，具有肩部和单个连续可擦拭表面的隔膜，隔膜和靴子预先穿刺的阀门，具有截头锥形延伸部的隔膜和单件隔膜和开启阀组合。注入口组件在联接和解耦期间提供零流体位移。

6. 发明授权

US5788215A Medical intravenous administration line connectors having a luer or pressure activated valve 失效
标题翻译：具有鲁尔或压力激活阀的医疗静脉内管线连接器
公开(公告)号：US5788215A
公开(公告)日：1998-08-04
申请号：US581057
申请日：1995-12-29
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： F16L37/42 , A61J1/00 , A61J1/20 , A61M39/24 , A61M39/26 , F16L37/28 , F16L41/03 , F16L41/16 , A61M5/00
CPC分类号： A61J1/2096 , A61M39/24 , A61M39/26 , A61J1/201 , A61J1/2037 , A61M2039/242 , A61M2039/2473 , A61M2039/2486
摘要： Medical intravenous administration connectors include a first coupling member having a female luer, a valve member having a substantially rigid stem and a substantially resilient body with a sealing surface, and a second coupling member having a fluid coupling extending from one end and an internal valve member support. The coupling members are structured to couple to each other with the valve member being biased to a closed position. When assembled, the valve stem extends into the female luer, and the valve body biases the sealing surface against an annular ring in the first coupling member thereby blocking fluid communication. Preferably, vanes are provided in the second coupling member on which the resilient body of the valve sits, with the vanes acting as a centering mechanism for the valve. The valve may be opened for fluid flow through the assembly by coupling a male luer to the female luer of the assembly, or by pressure actuation. Several valve members are disclosed and several structures for mating the first and second coupling members are disclosed. Y-injection sites and intravenous manifolds utilizing the valve arrangement and coupling members of the invention are also disclosed. All embodiments are easy to prime, limit priming volume, and are arranged without dead-spaces in which blood can be trapped.
摘要翻译：医疗静脉给药连接器包括具有阴路厄尔的第一联接构件，具有基本上刚性的杆的阀构件和具有密封表面的基本上弹性的主体，以及具有从一端延伸的流体联接件和内部阀构件的第二联接构件支持。联接构件被构造成彼此联接，阀构件被偏压到关闭位置。当组装时，阀杆延伸到母路厄尔中，并且阀体将密封表面抵靠第一联接构件中的环形圈偏压，从而阻止流体连通。优选地，叶片设置在阀的弹性体所在的第二联接构件中，叶片用作阀的定心机构。阀可以打开以通过将阳鲁尔连接到组件的阴路厄，或通过压力致动而流过组件。公开了几个阀构件，并且公开了用于配合第一和第二联接构件的若干结构。还公开了利用本发明的阀装置和联接构件的Y-注射部位和静脉内歧管。所有实施方案易于起始，限制起泡体积，并且布置成没有血液可被捕获的死空间。

7. 发明申请

US20090028750A1 Cleaning and Disinfection Swabbing Device for Needle-Free Intravenous (IV) Connectors 审中-公开
标题翻译：无针静脉（IV）连接器的清洁和消毒擦拭装置
公开(公告)号：US20090028750A1
公开(公告)日：2009-01-29
申请号：US11781480
申请日：2007-07-23
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： A61L2/18
CPC分类号： A61L2/26 , A61L2/18 , A61L2202/17 , A61L2202/24
摘要： A device for cleaning and disinfecting needle-free intravenous connectors includes a cap, a sponge-like absorbent material impregnated with a disinfectant agent, and a hermetic seal. The cap defines a cavity whose walls are lined with the absorbent material and is sized to receive a needle-free intravenous connector. A hermetic seal provided for the cap seals the cavity and preserves the disinfectant agent contained in the absorbent material. The device is used by removing the hermetic seal, placing the cavity of the cap over the septum and thread profile of the connector, pushing the cap down on the septum portion of the IV connector so that the outer threads and septum of the connector slidingly interfere with the absorbent material containing the disinfectant agent, and twisting the cap back and forth to clean and disinfect the septum and thread profile. The device is discarded after use.
摘要翻译：用于清洁和消毒无针静脉内连接器的装置包括帽，浸有消毒剂的海绵状吸收材料和气密密封。盖子限定了一个空腔，其腔壁上衬有吸收材料，并且其尺寸适于接收无针静脉注射连接器。为盖提供的气密密封件密封空腔并保留吸收材料中所含的消毒剂。该装置通过去除气密密封件，将盖的空腔放置在连接器的隔膜和螺纹轮廓上，将盖向下推到IV连接器的隔膜部分上，使得连接器的外螺纹和隔膜滑动地干涉吸收材料含有消毒剂，并且来回扭转帽以清洁和消毒隔膜和螺纹轮廓。设备在使用后丢弃。

8. 发明授权

US5954313A Medical intravenous administration line connectors having a luer activated valve 失效
标题翻译：具有鲁尔活化阀的医用静脉给药管路连接器
公开(公告)号：US5954313A
公开(公告)日：1999-09-21
申请号：US841281
申请日：1997-04-29
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： F16L37/42 , A61J1/00 , A61J1/20 , A61M5/162 , A61M39/24 , A61M39/26 , F16L37/28 , F16L41/03 , F16L41/16 , A61M5/00
CPC分类号： A61J1/2096 , A61M39/24 , A61M39/26 , F16L41/03 , F16L41/16 , A61J1/201 , A61J1/2037 , A61M2039/242 , A61M2039/2473 , A61M2039/2486 , A61M5/16813 , Y10S137/903 , Y10T137/7856 , Y10T137/7879
摘要： Medical intravenous administration connectors according to a first embodiment include a first coupling member having a female luer, a valve member having a substantially rigid stem and a substantially resilient body with a sealing surface, and a second coupling member having a fluid coupling extending from one end and an internal valve member support. The coupling members are structured to couple to each other with the valve member being biased to a closed position. When assembled, the valve stem extends into the female luer, and the valve body biases the sealing surface against an annular ring in the first coupling member thereby blocking fluid communication. Vanes are provided in the second coupling member on which the resilient body of the valve sits, with the vanes acting as a centering mechanism for the valve. The valve is opened for fluid flow through the assembly by coupling a male luer to the female luer of the assembly. According to a second embodiment, the valve stem is replaced by a dome-like protrusion on the resilient valve body. The valve of the second embodiment is opened by applying fluid under pressure through the female luer. According to a third embodiment, the valve is partially rigid and partially resilient. All embodiments are easy to prime, limit priming volume, and are arranged without dead-spaces in which blood can be trapped.
摘要翻译：根据第一实施例的医疗静脉内给药连接器包括具有阴路厄的第一联接构件，具有基本上刚性的杆的阀构件和具有密封表面的基本上弹性的主体，以及具有从一端延伸的流体联接件的第二联接构件和内部阀构件支撑件。联接构件被构造成彼此联接，阀构件被偏压到关闭位置。当组装时，阀杆延伸到母路厄尔中，并且阀体将密封表面抵靠第一联接构件中的环形圈偏压，从而阻止流体连通。叶片设置在阀的弹性体所在的第二联接构件中，叶片用作阀的定心机构。打开阀门，使液体通过组件通过将公路厄尔连接到组件的母路厄尔而流动。根据第二实施例，阀杆由弹性阀体上的圆顶状突起代替。第二实施例的阀通过在压力下施加流体通过母路厄尔打开。根据第三实施例，阀是部分刚性的并且部分弹性。所有实施方案易于起始，限制起泡体积，并且布置成没有血液可被捕获的死空间。

9. 发明授权

US5833213A Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe 失效
标题翻译：用于具有可刺破隔膜和无针注射器的小瓶的多剂量药物瓶适配器
公开(公告)号：US5833213A
公开(公告)日：1998-11-10
申请号：US906661
申请日：1997-08-07
申请人： Dana Wm. Ryan
发明人： Dana Wm. Ryan
IPC分类号： A61J1/00 , A61J1/20 , A61M5/162 , A61M39/24 , A61M39/26 , F16L37/28 , F16L41/03 , F16L41/16 , A61M5/00
CPC分类号： A61J1/2096 , A61M39/24 , A61M39/26 , A61M5/162 , A61J1/201 , A61J1/2058 , A61M2039/242 , A61M2039/2473 , A61M2039/2486 , Y10S604/905
摘要： A drug vial adapter according to the invention includes: a first coupling member having a female luer connector (preferably a luer lock) with a fluid path therethrough, a flange having a first sealing ring seat formed therein and a first mating structure; a second cylindrical coupling member having a centrally located septum piercing tube with a fluid path therethrough and a second mating structure; and a valve member including a valve stem and a resilient valve body having an annular sealing surface. A valve body seat is formed in the interior of the second coupling member by a plurality of radially arranged stepped vanes. According to a preferred embodiment, the second coupling member is formed as a stepped cylinder having a relatively large diameter adjacent the point of the septum piercing tube, a relatively small diameter adjacent the valve body seat and an intermediate diameter therebetween. The presently preferred valve body is substantially frustroconical having a relatively broad end with a stepped axial bore defining the annular sealing surface. The presently preferred valve stem has a stepped cylindrical portion which fits into the axial bore of the valve body and a pair of spaced apart upstanding members which extend into the female luer.
摘要翻译：根据本发明的药物瓶适配器包括：第一联接构件，其具有穿过其中的流体路径的阴路厄连接器（优选地是鲁尔锁），具有形成在其中的第一密封环座和第一配合结构的凸缘; 第二圆柱形联接构件，其具有位于中间的隔膜穿透管，其具有穿过其的流体路径和第二配合结构; 以及阀构件，其包括阀杆和具有环形密封表面的弹性阀体。通过多个径向布置的台阶叶片在第二联接构件的内部形成阀体座。根据优选实施例，第二联接构件形成为具有相邻较大直径的阶梯圆柱体，该间隔圆柱体邻近隔垫穿刺管，邻近阀体座的相对较小的直径以及它们之间的中间直径。目前优选的阀体基本截头圆锥形，具有相对宽的端部，其具有限定环形密封表面的台阶轴向孔。目前优选的阀杆具有阶梯状的圆柱形部分，其配合到阀体的轴向孔中，以及一对间隔开的直立构件，其延伸到阴路厄。

10. 发明授权

US5693031A Method of using reusable surgical trocar with disposable valve assembly 失效
标题翻译：使用可重复使用的手术套管针与一次性阀组件的方法
公开(公告)号：US5693031A
公开(公告)日：1997-12-02
申请号：US460552
申请日：1995-06-02
申请人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
发明人： Dana Wm. Ryan , Joel F. Giurtino , Thomas O. Bales
IPC分类号： A61B17/00 , A61B17/34 , A61M39/06 , A61M5/178
CPC分类号： A61M39/0606 , A61B17/3496 , A61B17/3498 , A61B17/3417 , A61B17/3474 , A61B2017/0023 , A61B2017/0046 , A61B2017/00477 , A61B2017/3464 , A61M2039/0626 , A61M2039/0633 , A61M2039/064 , A61M2039/0653 , A61M39/06 , Y10T137/7885
摘要： A surgical trocar assembly includes a disposable valve assembly, a cannula assembly, and a trocar with a handle. The cannula assembly includes a cannula base having a valve assembly coupling device at its proximal end, and a cannula extending from its distal end. The disposable valve assembly has a coupling device for removably coupling it with the cannula base. The valve assembly also includes a valve body with a fluid passage communicating with the hollow cannula when it is coupled to the cannula base. A slit or flapper valve and a universal washer are mounted within the valve body and allow the insertion of the trocar or other endoscopic instruments therethrough while providing a fluid sealing of the fluid passage. The valve assembly may be provided with a side port which optionally contains an automatic valve actuated by a luer coupling. Several different valve assembly-cannula base couplings are disclosed as well as several different types of trocars.
摘要翻译：手术套管针组件包括一次性阀组件，套管组件和带手柄的套管针。套管组件包括在其近端具有阀组件联接装置的套管基座和从其远端延伸的套管。一次性阀组件具有用于将其与插管基座可拆卸地联接的联接装置。阀组件还包括阀体，当其连接到套管基座时，具有与中空套管连通的流体通道。狭缝或挡板阀和通用垫圈安装在阀体内，并允许套管针或其他内窥镜器械插入，同时提供流体通道的流体密封。阀组件可以设置有侧端口，其可选地包含由鲁尔耦合器致动的自动阀。公开了几种不同的阀组件 - 套管基座联接器以及几种不同类型的套管针。

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