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1. 发明申请

US20130109052A1 STERILITY TEST METHOD AND TOTALLY ENCLOSED BACTERIAL AMPOULE INCUBATOR USED BY IT 有权
标题翻译：无菌试验方法和全部使用的细菌滋养细菌
公开(公告)号：US20130109052A1
公开(公告)日：2013-05-02
申请号：US13807558
申请日：2011-06-28
申请人： Dan Yan , Xiaohe Xiao , Ping Zhang , Yongshen Ren , Cheng Jin
发明人： Dan Yan , Xiaohe Xiao , Ping Zhang , Yongshen Ren , Cheng Jin
IPC分类号： C12Q1/04
CPC分类号： C12Q1/04 , C12N1/20 , C12Q1/22 , G01N25/20
摘要： A sterility test method includes: selecting strain and culture medium, preparing bacterial cultures, transcribing fingerprint characteristics in thermograms as indices to verify the characteristics, drawing the thermodynamic parameters of the thermogram, determining the positive judgment index and performing sterility test for the samples. A fully-enclosed bacteria collecting ampoule incubator includes bacteria collecting ampoule system, sample and liquid feeding system and peristalsis liquid discharge system. The sample and liquid feeding system is connected with the bacteria collecting ampoule system by the liquid intake tube; and the bacteria collecting ampoule system is connected with the peristalsis liquid discharge system by the liquid drainage tube. The invention is characterized by short inspection time, high sensitivity, high automation and accurate test results on microbial contamination. It can also provide the overall process curve on the growth conditions. Such curve is provided with relatively favorable fingerprint, which enables qualitative analysis on the microbial contamination conditions.
摘要翻译：无菌试验方法包括：选择菌株和培养基，制备细菌培养物，将热图中的指纹特征转录为指标，验证特征，绘制温谱图的热力学参数，确定阳性判断指标，并对样品进行无菌检验。全封闭细菌收集安瓿培养箱包括细菌收集安瓿系统，样品和液体供料系统和蠕动液体排放系统。样品和液体供给系统通过进液管与细菌收集安瓿系统连接; 细菌收集安瓿系统通过液体引流管与蠕动液体排放系统连接。本发明的特点是检测时间短，灵敏度高，自动化程度高，微生物污染检测结果准确。它还可以为生长条件提供总体过程曲线。这种曲线具有相对有利的指纹，可以对微生物污染条件进行定性分析。

2. 发明授权

US08778629B2 Sterility test method and totally enclosed bacterial ampoule incubator used by it 有权
标题翻译：无菌试验方法及全封闭的细菌安瓿培养箱
公开(公告)号：US08778629B2
公开(公告)日：2014-07-15
申请号：US13807558
申请日：2011-06-28
申请人： Dan Yan , Xiaohe Xiao , Ping Zhang , Yongshen Ren , Cheng Jin
发明人： Dan Yan , Xiaohe Xiao , Ping Zhang , Yongshen Ren , Cheng Jin
IPC分类号： C12Q1/22
CPC分类号： C12Q1/04 , C12N1/20 , C12Q1/22 , G01N25/20
摘要： A sterility test method includes: selecting strain and culture medium, preparing bacterial cultures, transcribing fingerprint characteristics in thermograms as indices to verify the characteristics, drawing the thermodynamic parameters of the thermogram, determining the positive judgment index and performing sterility test for the samples. A fully-enclosed bacteria collecting ampoule incubator includes bacteria collecting ampoule system, sample and liquid feeding system and peristalsis liquid discharge system. The sample and liquid feeding system is connected with the bacteria collecting ampoule system by the liquid intake tube; and the bacteria collecting ampoule system is connected with the peristalsis liquid discharge system by the liquid drainage tube. The invention is characterized by short inspection time, high sensitivity, high automation and accurate test results on microbial contamination. It can also provide the overall process curve on the growth conditions. Such curve is provided with relatively favorable fingerprint, which enables qualitative analysis on the microbial contamination conditions.
摘要翻译：无菌试验方法包括：选择菌株和培养基，制备细菌培养物，将热图中的指纹特征转录为指标，验证特征，绘制温谱图的热力学参数，确定阳性判断指标，并对样品进行无菌检验。全封闭细菌收集安瓿培养箱包括细菌收集安瓿系统，样品和液体供料系统和蠕动液体排放系统。样品和液体供给系统通过进液管与细菌收集安瓿系统连接; 细菌收集安瓿系统通过液体引流管与蠕动液体排放系统连接。本发明的特点是检测时间短，灵敏度高，自动化程度高，微生物污染检测结果准确。它还可以为生长条件提供总体过程曲线。这种曲线具有相对有利的指纹，可以对微生物污染条件进行定性分析。

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