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    • 10. 发明申请
    • METHOD AND COMPOSITION FOR DISPERSIONS OF GOLD NANOPARTICLES
    • 黄金纳米粒子分布的方法和组成
    • US20140234220A1
    • 2014-08-21
    • US14183229
    • 2014-02-18
    • Dan V. GoiaJohn I. NjagiCalin V. Pop
    • Dan V. GoiaJohn I. NjagiCalin V. Pop
    • A61K41/00A61K47/48
    • A61K47/6923
    • The present disclosure relates to a method for making a gold nanoparticle dispersion. The method includes providing a first solution that has gold ions in a liquid medium, adding NTA molecules to the first solution to form a gold nanoparticle dispersion. When the NTA molecules are added to the first solution, the NTA molecules act as a reducing agent to reduce the gold ions to gold atoms, after which the gold atoms nucleate to form gold nanoparticles. The excess NTA molecules then attach to the surface of the gold nanoparticles to stabilize the dispersion. The present disclosure also relates to a dispersion composition that includes a liquid medium, gold nanoparticles dispersed throughout the liquid medium, and NTA molecules directly coating the gold nanoparticles.
    • 本公开涉及一种制备金纳米颗粒分散体的方法。 该方法包括提供在液体介质中具有金离子的第一溶液,将NTA分子加入到第一溶液中以形成金纳米颗粒分散体。 当NTA分子被添加到第一溶液中时,NTA分子用作还原剂以将金离子还原成金原子,之后金原子成核形成金纳米颗粒。 然后过量的NTA分子附着到金纳米颗粒的表面以稳定分散体。 本公开还涉及包含液体介质,分散在整个液体介质中的金纳米颗粒和直接涂覆金纳米颗粒的NTA分子的分散体组合物。