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1. 发明授权

US08993724B2 Process for the preparation of glycosylated interferon beta 有权
标题翻译：制备糖基化干扰素β的方法
公开(公告)号：US08993724B2
公开(公告)日：2015-03-31
申请号：US13159864
申请日：2011-06-14
申请人： Dina Fischer , Alain Bernard , Paul Ducommun , Mara Rossi
发明人： Dina Fischer , Alain Bernard , Paul Ducommun , Mara Rossi
IPC分类号： A61K38/21 , C07K14/565 , C12P21/04 , C12N5/02 , C12N5/07 , C12N5/00 , C12N15/00
CPC分类号： C12N5/0031 , A61K38/215 , C07K14/565 , C12N5/0037 , C12N5/06 , C12N15/00 , C12N2500/12 , C12N2500/32 , C12N2500/90 , C12N2500/92 , C12N2500/99 , C12N2510/02
摘要： The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern.
摘要翻译：本发明涉及生产干扰素β的方法以及具有独特糖基化模式的干扰素β组合物。

2. 发明申请

US20110305669A1 PROCESS FOR THE PREPARATION OF GLYCOSYLATED INTERFERON BETA 有权
标题翻译：制备糖苷化干扰素的方法
公开(公告)号：US20110305669A1
公开(公告)日：2011-12-15
申请号：US13159864
申请日：2011-06-14
申请人： DINA FISCHER , Alain Bernard , Paul Ducommun , Mara Rossi
发明人： DINA FISCHER , Alain Bernard , Paul Ducommun , Mara Rossi
IPC分类号： A61K38/21 , C07K14/565 , C07K1/36 , C12P21/00
CPC分类号： C12N5/0031 , A61K38/215 , C07K14/565 , C12N5/0037 , C12N5/06 , C12N15/00 , C12N2500/12 , C12N2500/32 , C12N2500/90 , C12N2500/92 , C12N2500/99 , C12N2510/02
摘要： The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern.
摘要翻译：本发明涉及生产干扰素β的方法以及具有独特糖基化模式的干扰素β组合物。

3. 发明申请

US20080219952A1 Process For the Preparation of Glycosylated Interferon Beta 审中-公开
标题翻译：糖基化干扰素β的制备方法
公开(公告)号：US20080219952A1
公开(公告)日：2008-09-11
申请号：US12064422
申请日：2005-08-26
申请人： Dina Fischer , Alain Bernard , Paul Ducommun , Mara Rossi
发明人： Dina Fischer , Alain Bernard , Paul Ducommun , Mara Rossi
IPC分类号： A61K38/21 , C12P21/04 , C07K1/00 , C12N15/00 , A61P25/00 , C12N5/06 , C12N15/11 , C07K14/00
CPC分类号： C12N5/0031 , A61K38/215 , C07K14/565 , C12N5/0037 , C12N5/06 , C12N15/00 , C12N2500/12 , C12N2500/32 , C12N2500/90 , C12N2500/92 , C12N2500/99 , C12N2510/02
摘要： The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern.
摘要翻译：本发明涉及生产干扰素β的方法以及具有独特糖基化模式的干扰素β组合物。

4. 发明授权

US09108712B2 Airship with a controlled variable profile 有权
标题翻译：飞艇具有受控变量轮廓
公开(公告)号：US09108712B2
公开(公告)日：2015-08-18
申请号：US14004784
申请日：2012-03-07
申请人： Alain Bernard
发明人： Alain Bernard
IPC分类号： B64B1/58 , B64B1/04
CPC分类号： B64B1/58 , B64B1/04 , B64B1/62 , B64C2201/022 , B64C2201/101
摘要： The invention relates to an airship comprising a flexible envelope having at least one adjustment region provided with two longitudinal adjustment elements mounted in opposition and mobile in relation to each other between a maximum distancing position and a minimum distancing position, the two longitudinal adjustment elements being connected to each other by a group comprising a plurality of cables crossing the inner space of the envelope, each of the cables cooperating with a plurality or tightening points provided along each longitudinal element. The cables are connected to at least one tightening module that can exert a tightening or loosening action on the cables and thereby bring the longitudinal adjustment elements closer together or move them further away.
摘要翻译：本发明涉及一种飞艇，其包括具有至少一个调节区域的至少一个调节区域，该调节区域设置有两个纵向调整元件，两个纵向调节元件相对于彼此安装，并且在最大间距位置和最小间距位置之间相对移动，两个纵向调节元件连接通过包括穿过信封的内部空间的多个电缆的组彼此相互联系，每个电缆与沿着每个纵向元件设置的多个或紧固点配合。电缆连接到至少一个可在电缆上施加紧固或松动的紧固模块，从而使纵向调节元件更靠近在一起或将它们移开。

5. 发明申请

US20070202597A1 Process For Recycling Solid Supports For Cultivation Of Anchorage-Dependent Cells 失效
标题翻译：回收固体支持植物依赖性细胞培养的方法
公开(公告)号：US20070202597A1
公开(公告)日：2007-08-30
申请号：US10580777
申请日：2004-11-26
申请人： Alain Bernard , Frederic Papp
发明人： Alain Bernard , Frederic Papp
IPC分类号： C12M3/04 , C12N5/00
CPC分类号： C12N5/0068 , C12N5/0075 , C12N2533/30
摘要： This invention relates to methods for use in industrial production of proteins. Specifically, the present invention provides a method of recycling solid supports for cultivation of anchorage-dependent cells such as, e.g., microcarriers and Fibra-Cel® disks. Solid supports recycled by a method of the present invention allow obtaining a protein productivity level comparable to the productivity level obtained with non-recycled solid support. The method comprises the steps of rinsing with water, rinsing with a sodium hydroxide solution and second rinsing step with water.
摘要翻译：本发明涉及用于工业生产蛋白质的方法。具体地说，本发明提供一种循环固体支持物的方法，用于培养锚定依赖细胞，例如微载体和Fibra-Cel盘。通过本发明的方法回收的固体支持物可以获得与用非再循环固体支持物获得的生产力水平相当的蛋白质生产率水平。该方法包括用水冲洗，用氢氧化钠溶液冲洗和用水冲洗第二步骤的步骤。

6. 外观设计

USD373599S Photo album 失效
公开(公告)号：USD373599S
公开(公告)日：1996-09-10
申请号：US41664
申请日：1995-07-20
申请人： Alain Bernard
设计人： Alain Bernard

7. 发明申请

US20060015407A1 Server and connection interface for establishing and controlling an IP communication 审中-公开
标题翻译：用于建立和控制IP通信的服务器和连接接口
公开(公告)号：US20060015407A1
公开(公告)日：2006-01-19
申请号：US11175782
申请日：2005-07-05
申请人： Alain Bernard , Remy Didier
发明人： Alain Bernard , Remy Didier
IPC分类号： G06Q20/00
CPC分类号： H04L65/1069 , G06Q20/204 , H04L12/14 , H04L12/1439 , H04L12/1813 , H04L67/14 , H04L67/36 , H04M15/55 , H04M15/56 , H04M2215/202 , H04M2215/2046 , H04M2215/22
摘要： The invention concerns a server connected to an Internet-type communication network, for distributing to a personal computer-type piece of computer equipment an interface that allows a user to use at least one control element to activate and deactivate a computer connection with the server and to establish an IP-type communication, the interface being such that the computer connection is activated by pressing on a push button such as a command button or a computer mouse button, the computer connection is maintained by maintaining the pressure on the push button, and the computer connection is deactivated by releasing the push button, and/or the interface being such that the computer connection is maintained by periodically pressing on a push button such as a command button or a computer mouse button.
摘要翻译：本发明涉及连接到因特网型通信网络的服务器，用于向个人计算机类型的计算机设备分配一个允许用户使用至少一个控制元件来激活和停用与服务器的计算机连接的接口，以及为了建立IP型通信，该接口使得通过按下诸如命令按钮或计算机鼠标按钮之类的按钮来激活计算机连接，通过维持按钮上的压力来维持计算机连接，以及通过释放按钮来禁用计算机连接，和/或通过周期性地按下诸如命令按钮或计算机鼠标按钮的按钮来维持计算机连接的界面。

8. 发明授权

US06360946B1 Vandal proof electronic memory card reader 失效
标题翻译：防破坏电子存储卡读卡器
公开(公告)号：US06360946B1
公开(公告)日：2002-03-26
申请号：US09601399
申请日：2000-08-02
申请人： Alain Bernard
发明人： Alain Bernard
IPC分类号： G06A706
CPC分类号： G06K7/003 , G06K7/0021
摘要： An electronic memory card reader (10) for reading a card comprising a card body (11) and electrical contact areas (12). The reader includes a read head (100) having connection elements (112) designed to cooperate with the contact areas (12), an insertion slot (200), an abutment (300) for the card body, defining a processing position in which the areas (12) are in contact with the connection elements (112), and a moving part (400) that is rotatable, and that is capable, firstly, in a closed position, of establishing electrical contact between the elements (112) and the areas (12) in the processing position and, secondly, of moving away from the closed position under the action of a force developed by the card (10) moving in translation. The part (400) is returned to the closed position by resilient return means (600).
摘要翻译：一种用于读取包括卡体（11）和电接触区域（12）的卡的电子存储卡读卡器（10）。读取器包括具有连接元件（112）的读取头（100），该连接元件被设计成与接触区域（12），插入槽（200），卡体的邻接（300）配合，限定了处理位置，区域（12）与连接元件（112）接触，并且可移动部件（400）可旋转并且首先能够处于关闭位置，以在元件（112）和第二元件（112）之间建立电接触在处理位置的区域（12），以及其次在由卡（10）移动的平移中产生的力的作用下离开关闭位置。部件（400）通过弹性回复装置（600）返回到关闭位置。

9. 发明授权

US4799386A Electrostatic accelerometer with dual electrical connection to its test mass 失效
标题翻译：静电加速度计与其测试质量具有双重电气连接
公开(公告)号：US4799386A
公开(公告)日：1989-01-24
申请号：US10441
申请日：1986-12-30
申请人： Alain Bernard , Pierre Touboul
发明人： Alain Bernard , Pierre Touboul
IPC分类号： G01P15/13 , G01P15/18 , G01P15/125 , G01P3/44
CPC分类号： G01P15/18 , G01P15/131 , G01P2015/0828
摘要： An acceleromter having a test weight movable in relation to a frame includes three pairs of mutually electrically orthogonal conducting parallel faces (1-6). Electrodes connected to the frame form capacitors with faces of the test weight. The six faces form two sets of three faces (1-3) and (4-6). The faces of a set form a first conductor insulated from the faces of the second set which form a second conductor. Position sensing voltages are applied to first and second conductors through very flexible leads (7 and 8). Position control voltages derived from the position sensing voltages are applied to the electrodes.
摘要翻译：具有可相对于框架移动的测试重量的加速度计包括三对相互电正交的导电平行面（1-6）。连接到框架的电极形成具有测试重量面的电容器。六面形成两组三面（1-3）和（4-6）。集合的面形成与第二组的面绝缘的第一导体，其形成第二导体。位置检测电压通过非常柔性的引线（7和8）施加到第一和第二导体。从位置检测电压得到的位置控制电压被施加到电极。

10. 发明授权

US4347292A Electric cell assembly with an alkaline electrolyte and current output wires 失效
标题翻译：电池组件采用碱性电解液和电流输出线
公开(公告)号：US4347292A
公开(公告)日：1982-08-31
申请号：US276981
申请日：1981-06-24
申请人： Alain Bernard , Raymond Bonnaterre
发明人： Alain Bernard , Raymond Bonnaterre
IPC分类号： H01M2/30 , H01M2/20 , H01M2/32
CPC分类号： H01M2/20
摘要： The invention relates to an electric cell assembly with an alkaline electrolyte and its current output wires (2, 3) electrically connected to the positive terminal and negative terminal of the electric cell assembly.The metal wire (3) which corresponds to the negative terminal (1) is surrounded, near said terminal and entirely outside the electric cell, with a glass bead (4) which is practically unalterable by the electrolyte.
摘要翻译：本发明涉及一种具有碱性电解质的电池组件及其与电池组件的正端子和负极端子电连接的电流输出线（2,3）。与负极端子（1）对应的金属线（3）在所述端子附近并且完全在电池的外部被玻璃珠（4）包围，所述玻璃珠（4）几乎不能被电解质改变。

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