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1. 发明申请

US20080097278A1 Treatment of Skin with Light and a Benefit Agent 审中-公开
标题翻译：用光和受益剂治疗皮肤
公开(公告)号：US20080097278A1
公开(公告)日：2008-04-24
申请号：US11572166
申请日：2005-07-15
申请人： Curtis A. Cole , Elvin Lukenbach , Gregory Skover
发明人： Curtis A. Cole , Elvin Lukenbach , Gregory Skover
IPC分类号： A61N5/06 , A61K35/00 , A61K38/02
CPC分类号： A61N5/062 , A61N5/0616 , A61N2005/0662
摘要： Methods of mitigating effects of aging on skin include a first skin treatment to an expanse of skin, and after a delay, providing a second skin treatment to the same expanse of skin. The skin treatments may include initiating exposure of an expanse of skin to light; terminating the exposure of the expanse of skin to the light after a period, preferably of less than about one hour; and applying a first benefit agent treatment to the expanse of skin after a first delay following the termination.
摘要翻译：减轻老化对皮肤的影响的方法包括对皮肤a a进行第一次皮肤治疗，并且在延迟之后，对同一片皮肤进行第二次皮肤治疗。皮肤治疗可能包括开始将一片皮肤暴露于光; 终止一段时间后，优选少于约1小时的皮肤暴露于光下; 以及在终止后的第一延迟之后对皮肤的宽度施加第一有益剂治疗。

2. 发明申请

US20090220442A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS 审中-公开
标题翻译：含有二苯甲酰基甲烷，氨基羟基苯甲酮，三氮唑和作为紫外线过滤剂的三唑的SUNSCREEN组合物
公开(公告)号：US20090220442A1
公开(公告)日：2009-09-03
申请号：US12065013
申请日：2006-07-07
申请人： Anne Sophie Brillouet , Isabelle Tischenbach , Carole Dupressoir , Curtis A. Cole
发明人： Anne Sophie Brillouet , Isabelle Tischenbach , Carole Dupressoir , Curtis A. Cole
IPC分类号： A61K8/41 , A61K8/35 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/35 , A61K8/496 , A61K8/4966 , A61K2800/59 , A61Q17/04
摘要： The present invention relates to a composition comprising: a) a dibenzoylmethane derivative UV-A absorbing agent, b) a hydroxybenzophenone, c) a triazine derivative, and d) a triazole derivative, and the topical use thereof in protecting mammalian skin or hair from UV radiation.
摘要翻译：本发明涉及一种组合物，其包含：a）二苯甲酰甲烷衍生物UV-A吸收剂，b）羟基二苯甲酮，c）三嗪衍生物，和d）三唑衍生物，以及其在哺乳动物皮肤或毛发中的局部应用紫外线辐射。

3. 发明申请

US20100226861A1 TOPICAL COMPOSITION DETECTION 审中-公开
标题翻译：主题成分检测
公开(公告)号：US20100226861A1
公开(公告)日：2010-09-09
申请号：US12761461
申请日：2010-04-16
申请人： Curtis A. Cole , Nikiforos Kollias
发明人： Curtis A. Cole , Nikiforos Kollias
IPC分类号： A61K49/00 , A61P43/00
CPC分类号： A61Q17/04 , A61K8/02 , A61K2800/434 , A61K2800/438 , A61K2800/88 , G01N21/64
摘要： Compositions, devices, methods, and kits are provided for determining the presence of topical compositions on surfaces, such as skin.
摘要翻译：提供组合物，装置，方法和试剂盒以确定表面如皮肤上局部组合物的存在。

4. 发明授权

US5340567A Sunscreen compositions 失效
标题翻译：防晒组合物
公开(公告)号：US5340567A
公开(公告)日：1994-08-23
申请号：US827908
申请日：1992-01-30
申请人： Curtis A. Cole , Martin K. O. Lindemann , Elvin R. Lukenbach , Ralph C. Stutzman
发明人： Curtis A. Cole , Martin K. O. Lindemann , Elvin R. Lukenbach , Ralph C. Stutzman
IPC分类号： A61K8/00 , A61K20060101 , A61K8/27 , A61K8/29 , A61K9/10 , A61Q17/04 , C01G20060101 , A61K7/42
CPC分类号： A61Q17/04 , A61K8/27 , A61K8/29 , A61K2800/412 , Y10S514/938
摘要： Novel sunscreen compositions containing titanium dioxide having a particle size less than about 35 m.mu. and zinc oxide having a particle size less than about 50 m.mu. are described as well as methods of protecting the skin from damaging ultraviolet radiation.
摘要翻译：描述了包含粒度小于约35μm的二氧化钛和粒径小于约50μm的氧化锌的新型防晒组合物以及保护皮肤免受紫外线辐射损害的方法。

5. 发明授权

US6068847A Cosmetic compositions 失效
标题翻译：化妆品组合物
公开(公告)号：US6068847A
公开(公告)日：2000-05-30
申请号：US940880
申请日：1997-09-30
申请人： Margaret Aleles , Claudia Kaminski , Curtis A. Cole
发明人： Margaret Aleles , Claudia Kaminski , Curtis A. Cole
IPC分类号： A61K8/00 , A61K8/14 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/37 , A61K8/41 , A61K8/67 , A61Q17/00 , A61Q19/00 , A61K7/48
CPC分类号： A61Q19/00 , A61K8/14 , A61K8/671 , A61Q17/00 , A61K2800/522 , A61K2800/75 , Y10S514/844 , Y10S514/846 , Y10S514/937
摘要： This invention relates to low-irritation profile compositions for skin care containing retinoids.
摘要翻译：本发明涉及含有类视黄醇的皮肤护理的低刺激性外形组合物。

6. 发明申请

US20100224795A1 TOPICAL COMPOSITION DETECTION 审中-公开
公开(公告)号：US20100224795A1
公开(公告)日：2010-09-09
申请号：US12760585
申请日：2010-04-15
申请人： Curtis A. Cole , Nikiforos Kollias
发明人： Curtis A. Cole , Nikiforos Kollias
IPC分类号： G01J1/58
CPC分类号： A61Q17/04 , A61K8/02 , A61K2800/434 , A61K2800/438 , A61K2800/88 , G01N21/64
摘要： Compositions, devices, methods, and kits are provided for determining the presence of topical compositions on surfaces, such as skin.

7. 发明授权

US07396526B1 Skin care composition 失效
标题翻译：护肤组合物
公开(公告)号：US07396526B1
公开(公告)日：2008-07-08
申请号：US09565716
申请日：2000-05-05
申请人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski , Victoria Van Leeuwen , Elvin R. Lukenbach
发明人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski , Victoria Van Leeuwen , Elvin R. Lukenbach
IPC分类号： A61K31/74 , A61K9/00 , A61K8/02
CPC分类号： A61K8/365 , A61K8/368 , A61K8/671 , A61Q19/00 , A61Q19/08
摘要： There are provided compositions which include a retinoid and preferably retinal; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinal; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.
摘要翻译：提供了包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 和挥发性碱，例如氢氧化铵。本发明的另一个实施方案包括包含类视黄醇并优选视黄醛的组合物; 皮肤病学活性的酸; 挥发性碱和第二中和剂。还提供了组合物，其包含类视黄醇，皮肤病学活性酸的中和铵盐，以及任选的除铵盐之外的中和盐。还提供了减少有需要的哺乳动物的细纹，皱纹，皮肤粗糙度和孔径以及增加皮肤表面的清晰度，细胞周转，皮肤光泽，皮肤光滑度，皮肤渗透或胶原蛋白合成的方法。如上所述的组合物局部施用于动物的皮肤。

8. 发明授权

US06544531B1 Skin care composition 有权
标题翻译：护肤组合物
公开(公告)号：US06544531B1
公开(公告)日：2003-04-08
申请号：US09436867
申请日：1999-11-09
申请人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski , Victoria Van Leeuwen
发明人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski , Victoria Van Leeuwen
IPC分类号： A61K600
CPC分类号： A61Q19/00 , A61K8/365 , A61K8/368 , A61K8/671 , A61Q19/08 , Y10S977/926
摘要： There are provided compositions which include a retinoid and preferably retinol; a dermatologically active acid; and a volatile base, such as ammonium hydroxide. Another embodiment of the invention includes compositions comprising a retinoid and preferably retinol; a dermatologically active acid; a volatile base; and a second neutralizing agent. There are also provided compositions which include a retinoid, a neutralized ammonium salt of a dermatologically active acid, and optionally a neutralized salt, other than ammonium salt, of an acid. Further provided are methods for reducing fine lines, wrinkles, skin roughness, and pore size and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.
摘要翻译：提供了包含类视色素并且优选视黄醇的组合物; 皮肤病学活性的酸; 和挥发性碱，例如氢氧化铵。本发明的另一个实施方案包括含有类视黄醇并优选视黄醇的组合物; 皮肤病学活性的酸; 挥发性碱和第二中和剂。还提供了组合物，其包含类视黄醇，皮肤病学活性酸的中和铵盐，以及任选的除铵盐之外的中和盐。还提供了减少有需要的哺乳动物的细纹，皱纹，皮肤粗糙度和孔径以及增加皮肤表面的清晰度，细胞周转，皮肤光泽，皮肤光滑度，皮肤渗透或胶原蛋白合成的方法。如上所述的组合物局部施用于动物的皮肤。

9. 发明授权

US06521237B2 Skin care composition 有权
标题翻译：护肤组合物
公开(公告)号：US06521237B2
公开(公告)日：2003-02-18
申请号：US09325452
申请日：1999-06-03
申请人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski
发明人： Curtis A. Cole , Laura E. Flack , Claudia Kaminski
IPC分类号： A61K600
CPC分类号： A61Q19/00 , A61K8/365 , A61K8/368 , A61K8/671 , A61Q19/08 , Y10S977/926
摘要： There are provided compositions which include a retinoid and preferably retinol; an acid; and an acid neutralizing effective amount of ammonium hydroxide. There are also provided compositions which include a retinoid and a neutralized ammonium salt of an acid. Further provided are methods for reducing fine lines and wrinkles and for increasing the clarity of a skin surface, cellular turnover, skin radiance, skin smoothness, skin permeation or collagen synthesis in a mammal in need thereof. Compositions as described above are administered topically to the skin of the animal.
摘要翻译：提供了包含类视色素并且优选视黄醇的组合物; 酸; 和酸中和有效量的氢氧化铵。还提供了包含类视黄醇和酸的中和的铵盐的组合物。进一步提供了有需要的哺乳动物减少细纹和皱纹并增加皮肤表面的清晰度，细胞周转，皮肤光泽，皮肤光滑度，皮肤渗透或胶原蛋白合成的方法。如上所述的组合物局部施用于动物的皮肤。

10. 发明授权

US06461622B2 Topical compositions 失效
标题翻译：专题作品
公开(公告)号：US06461622B2
公开(公告)日：2002-10-08
申请号：US08807351
申请日：1997-02-27
申请人： Jue-Chen Liu , Jonas C. T. Wang , Mohammed Yusuf , Norihiro Yamamoto , Satoshi Kazama , Christopher R. Stahl , Jean P. Holland , Kamran Mather , Margaret A. Aleles , Sachio Hamada , Curtis A. Cole , Stephen J. Wisniewski
发明人： Jue-Chen Liu , Jonas C. T. Wang , Mohammed Yusuf , Norihiro Yamamoto , Satoshi Kazama , Christopher R. Stahl , Jean P. Holland , Kamran Mather , Margaret A. Aleles , Sachio Hamada , Curtis A. Cole , Stephen J. Wisniewski
IPC分类号： A61K600
CPC分类号： A61K8/06 , A61K8/062 , A61K8/671 , A61K2800/51 , A61K2800/522 , A61K2800/75 , A61K2800/88 , A61Q17/04 , A61Q19/00 , A61Q19/02 , Y10S514/844 , Y10S514/847 , Y10S514/887 , Y10S514/938 , Y10S514/941
摘要： Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability.
摘要翻译：皮肤护理组合物包含含有类视黄醇并具有良好物理和化学稳定性的水包油乳液基质。

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