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1. 发明申请

US20060082589A1 Brush texture apparatus and method 有权
标题翻译：刷纹理装置和方法
公开(公告)号：US20060082589A1
公开(公告)日：2006-04-20
申请号：US10968156
申请日：2004-10-20
申请人： Craig Bixler , Ping Li , David Brown
发明人： Craig Bixler , Ping Li , David Brown
IPC分类号： G09G5/00
CPC分类号： G06T11/001
摘要： Techniques for superimposing highlights and shadows onto a background in order to simulate a brush texture graphical style within a software application's component window. The techniques include decoding a user-selected base-color into its individual color components, performing a contrast operation on the individual color components to determine highlight and shadow colors, and superimposing the highlight and shadow colors onto the user selected background.
摘要翻译：将高光和阴影叠加到背景上以便在软件应用程序的组件窗口中模拟画笔纹理图形样式的技术。这些技术包括将用户选择的基色解码成其单独的颜色分量，对各个颜色分量执行对比度操作以确定高光和阴影颜色，以及将高亮和阴影颜色叠加到用户选择的背景上。

2. 发明申请

US20060109278A1 Color melding apparatus and method 有权
标题翻译：彩色熔接设备及方法
公开(公告)号：US20060109278A1
公开(公告)日：2006-05-25
申请号：US10995197
申请日：2004-11-24
申请人： Craig Bixler , Ping Li , David Brown
发明人： Craig Bixler , Ping Li , David Brown
IPC分类号： G09G5/02
CPC分类号： G06T11/001
摘要： Techniques for locating an array of melded colors onto a software application's component window in order to create three-dimensional and multicolor graphics within the component window. The techniques include decoding a first and second color into their respective individual color components, performing a transition operation on the foregoing color components to determine transition colors, dividing a portion of the component window into subcomponents, and locating the transition colors into the subcomponents and, thereby, create three-dimensional and multicolor graphics within the component window.
摘要翻译：用于将一系列熔合颜色定位到软件应用程序组件窗口上以便在组件窗口内创建三维和多色图形的技术。这些技术包括将第一和第二颜色解码成它们各自的颜色分量，对前述颜色分量执行转换操作以确定转换颜色，将部分窗口的一部分划分为子部件，以及将转换颜色定位到子部件中，从而在组件窗口中创建三维和多色图形。

3. 发明申请

US20050282566A1 Apparatus and method for constructing and routing a message 审中-公开
标题翻译：用于构建和路由消息的装置和方法
公开(公告)号：US20050282566A1
公开(公告)日：2005-12-22
申请号：US11136551
申请日：2005-05-25
申请人： Craig Bixler , David Brown , Ping Li
发明人： Craig Bixler , David Brown , Ping Li
IPC分类号： G06F19/00 , G06Q10/00 , H04Q7/20
CPC分类号： G06Q10/00 , G06F19/3418 , G06Q50/22 , G16H40/20
摘要： An apparatus and method for responding to an input signal by accessing a data source, retrieving relevant data and utilizing the data to construct and route an outgoing message. Using this apparatus and method, hospitals can provide efficient and personalized responses to patient requests, which can be initialized via a nurse call device. These efficient and personalized responses are accomplished by accessing a data source to obtain specific information about a patent, and then routing relevant portions of the information, via a text message, to those having privy to the information and responsible for caring for the patient.
摘要翻译：一种用于通过访问数据源来响应输入信号的装置和方法，检索相关数据并利用数据来构建和路由输出消息。使用这种装置和方法，医院可以为患者请求提供有效和个性化的响应，其可以通过护士呼叫装置来初始化。这些有效和个性化的响应是通过访问数据源来获得关于专利的特定信息来实现的，然后通过文本消息将信息的相关部分路由到对信息不了解并负责照顾病人的信息。

4. 发明申请

US20070249615A1 Pyridine [3,4-b] Pyrazinones 有权
标题翻译：吡啶[3,4-b]吡嗪酮
公开(公告)号：US20070249615A1
公开(公告)日：2007-10-25
申请号：US11737966
申请日：2007-04-20
申请人： Robert Hughes , Andrew Bell , David Brown , Dafydd Owen , Michael Palmer , Christopher Phillips , David Brown , Yvette Fobian , John Freskos , Steven Heasley , E. Jacobsen , Todd Maddux , Brent Mischke , John Molyneaux , Joseph Moon , D. Rogier , Michael Tollefson , John Walker
发明人： Robert Hughes , Andrew Bell , David Brown , Dafydd Owen , Michael Palmer , Christopher Phillips , David Brown , Yvette Fobian , John Freskos , Steven Heasley , E. Jacobsen , Todd Maddux , Brent Mischke , John Molyneaux , Joseph Moon , D. Rogier , Michael Tollefson , John Walker
IPC分类号： A61K31/498 , C07D487/02
CPC分类号： C07D471/04
摘要： Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein R2, R6A, R6B and R8 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, synthetic methods, and intermediates are also disclosed.
摘要翻译：公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有式I的结构：其中R 2，R 6A，R 6B， >和R＆gt; 8如说明书中所定义。还公开了相应的药物组合物，治疗方法，合成方法和中间体。

5. 发明公开

US20240026317A1 PAN-RAS mRNA CANCER VACCINES 审中-公开
公开(公告)号：US20240026317A1
公开(公告)日：2024-01-25
申请号：US18249023
申请日：2021-10-13
申请人： Dong SHEN , David BROWN , Renxiang CHEN , RNAimmune, Inc
发明人： Dong Shen , David Brown , Renxiang Chen
IPC分类号： C12N9/14 , C12P19/30 , A61K39/00 , A61K9/127 , A61K47/69 , A61P35/00 , A61K47/54
CPC分类号： C12N9/14 , C12Y306/05002 , C12P19/30 , A61K39/001164 , A61K9/1273 , A61K47/6911 , A61P35/00 , A61K47/54 , A61K2039/53 , A61K2039/585 , A61K2039/55555
摘要： Compositions and methods are provided for potent mRNA vaccines for treatment of cancers with a mutation in the ras gene family. The compositions include a pharmaceutical composition comprising, or consisting essentially of, or yet further comprising mRNA molecules encoding at least one of multiple peptides of a group of somatic mutants and a pharmaceutically acceptable carrier. Methods for stimulating system immune responses and treatment are provided, including intratumoral, intravenous, intramuscular, intradermal, or subcutaneous injection of the composition as disclosed herein.

6. 发明授权

US11345606B2 Deposition particles and a method and apparatus for producing the same 有权
公开(公告)号：US11345606B2
公开(公告)日：2022-05-31
申请号：US15435318
申请日：2017-02-17
申请人： David Brown
发明人： David Brown
IPC分类号： G02B6/02 , C01G23/053 , C01G49/06 , C01B33/18
摘要： Disclosed is a method for producing deposition particles or intermediate particles, characterized in that the method comprises: forming a solution comprising a solvent and one or more deposit sources, aerosolizing the formed solution to produce an aerosol of precursor particles comprising the deposit source, conditioning the precursor particles to produce deposition particles or intermediate particles from the deposit source and collecting said particles. The particles may be collected as a deposit or precursor deposit on a substrate. The particles may include a matrix material and a dopant. The conditioning may be quenched to produce a desired substructure. The matrix material may be essentially optically clear. The substrate may comprise an optical fiber or an optical fiber preform or mandrel.

7. 外观设计

USD819777S1 Fishing lure mold 有权
公开(公告)号：USD819777S1
公开(公告)日：2018-06-05
申请号：US29581051
申请日：2016-10-14
申请人： David Brown
设计人： David Brown

8. 发明申请

US20170128079A1 ADJUSTABLE CUT BLOCK AND SIZER INSTRUMENT FOR ARTHROPLASTY PLANNING 审中-公开
公开(公告)号：US20170128079A1
公开(公告)日：2017-05-11
申请号：US15343765
申请日：2016-11-04
申请人： David Brown
发明人： David Brown
IPC分类号： A61B17/15
CPC分类号： A61B17/155
摘要： An integrated instrument for arthroplasty planning comprises a cutting block having an adjustable distance between an anterior cut guide and a posterior cut guide, and a sizer mounted to the cutting block, the sizer comprising medial and lateral posterior feet having an adjustable distance from one of the cut guides and an adjustable angular position relative to the one of the cut guides.

9. 发明授权

US09612287B2 Non-sequential monitoring of battery cells in battery monitoring systems, and related components, systems, and methods 有权
公开(公告)号：US09612287B2
公开(公告)日：2017-04-04
申请号：US13461862
申请日：2012-05-02
申请人： David Brown , Christopher James Belcher , Duncan Joseph Brown , Dat Tan Chau
发明人： David Brown , Christopher James Belcher , Duncan Joseph Brown , Dat Tan Chau
IPC分类号： H02J7/00 , G01R31/36 , H02J9/04
CPC分类号： G01R31/3631 , G01R31/3658 , G01R31/3662 , H02J7/0021 , H02J9/04
摘要： Non-sequential monitoring of battery cells in battery monitoring systems, and related components, systems, and methods are disclosed. In one embodiment, a battery monitoring system control unit is provided. The battery monitoring system control unit is configured to control battery monitoring devices. Each battery monitoring device is configured to be coupled to a subset of battery cells electrically connected in series in a sequential order to form a battery. The battery monitoring system control unit is further configured to instruct the battery monitoring devices to test an ohmic value of each battery cell of the battery cells of the battery in a non-sequential order. In this manner, heat generated in the battery monitoring devices from the testing may be more effectively dissipated, which can also allow for the battery monitoring devices to be employed in higher operating temperature environments.

10. 发明申请

US20160130026A1 COLLAPSIBLE BEVERAGE CONTAINMENT DEVICE 审中-公开
标题翻译：不可饮用的饮料包装设备
公开(公告)号：US20160130026A1
公开(公告)日：2016-05-12
申请号：US14534692
申请日：2014-11-06
申请人： David Brown , Sheletia Brown
发明人： David Brown , Sheletia Brown
IPC分类号： B65D1/02 , B65D41/04 , B65D47/06 , B65D1/40
CPC分类号： B65D1/0292 , B65D1/0284 , B65D1/40 , B65D2501/0036
摘要： A collapsible beverage containment assembly includes a bottle. The bottle has an outer wall extending between a top end and a bottom end of the bottle to contain a carbonated fluid. The outer wall is structured such that the bottle is collapsible. A sleeve is coupled to the bottom end. The sleeve is positioned within an interior of the bottle. A lid is movably coupled to the top end so the lid may be rotated. A screw is coupled to the lid such that the screw extends downwardly into the bottle. The screw engages the sleeve. Thus, the outer wall is collapsed when the lid is rotated to reduce a volume of the bottle, preserving the carbonation in the carbonated beverage.
摘要翻译：可折叠的饮料容纳组件包括瓶子。瓶子具有在瓶的顶端和底端之间延伸以容纳碳酸液体的外壁。外壁的结构使得瓶子可折叠。套筒连接到底端。套筒位于瓶子的内部。盖子可移动地联接到顶端，因此盖子可以旋转。螺钉联接到盖上，使得螺钉向下延伸到瓶中。螺钉接合套筒。因此，当盖旋转以减小瓶的体积时，外壁被折叠，从而保持碳酸饮料中的碳酸化。

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