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1. 发明授权

US07445594B1 Method and apparatus for temporarily immobilizing a local area of tissue 有权
标题翻译：临时固定组织局部区域的方法和装置
公开(公告)号：US07445594B1
公开(公告)日：2008-11-04
申请号：US09678203
申请日：2000-10-02
申请人： Cornelius Borst , Hendricus J. Mansvelt Beck , Paul F. Grundeman , Cornelis Wilhelmus Jozef Verlaan
发明人： Cornelius Borst , Hendricus J. Mansvelt Beck , Paul F. Grundeman , Cornelis Wilhelmus Jozef Verlaan
IPC分类号： A61F2/00 , A61F13/00 , A61B19/00
CPC分类号： A61B17/02 , A61B17/0206 , A61B90/50 , A61B2017/00243 , A61B2017/00398 , A61B2017/00703 , A61B2017/0243 , A61B2017/306
摘要： A method and apparatus for temporarily immobilizing a local area of tissue. In particular, the present invention provides a method and apparatus for temporarily immobilizing a local area of tissue within a patient's body cavity. In one embodiment, the tissue immobilized is heart tissue to thereby permit surgery on a coronary vessel in that area without significant deterioration of the pumping function of the beating heart. The local area of heart tissue is immobilized to a degree sufficient to permit minimally invasive or micro-surgery on that area of the heart. The apparatus for temporarily immobilizing a local area of tissue includes a first tissue engaging member and a second tissue engaging member coupled to a spreader. The spreader is operated by an actuator to selectively control the movement of the first tissue engager and the second tissue engager. The method for temporarily immobilizing a local area of tissue includes controlling the spreading of the first tissue engaging member and the second tissue engaging member so a selective amount of spreading occurs.
摘要翻译：一种临时固定组织局部区域的方法和装置。特别地，本发明提供了一种临时固定患者体腔内的组织局部区域的方法和装置。在一个实施方案中，固定的组织是心脏组织，从而允许在该区域的冠状血管上进行手术，而不会显着降低跳动心脏的泵送功能。心脏组织的局部区域被固定到足以允许在该区域的微创或微手术的程度。用于临时固定组织局部区域的装置包括第一组织接合构件和联接到扩展器的第二组织接合构件。扩张器由致动器操作以选择性地控制第一组织接合器和第二组织接合器的运动。用于临时固定组织局部区域的方法包括控制第一组织接合构件和第二组织接合构件的扩展，从而发生选择性的扩展。

2. 发明授权

US07189201B2 Method and apparatus for temporarily immobilizing a local area of tissue 有权
标题翻译：临时固定组织局部区域的方法和装置
公开(公告)号：US07189201B2
公开(公告)日：2007-03-13
申请号：US10137159
申请日：2002-04-30
申请人： Cornelius Borst , Hendricus J. Mansvelt Beck , Paul F. Grundeman , Cornelis Wilhelmus Jozef Verlaan
发明人： Cornelius Borst , Hendricus J. Mansvelt Beck , Paul F. Grundeman , Cornelis Wilhelmus Jozef Verlaan
IPC分类号： A61F2/00 , A61F13/00 , A47J45/00 , A61B19/00
CPC分类号： A61B17/02 , A61B17/0206 , A61B90/50 , A61B2017/00243 , A61B2017/00398 , A61B2017/00703 , A61B2017/0243 , A61B2017/306
摘要： A method and apparatus for temporarily immobilizing a local area of tissue. In particular, the present invention provides a method and apparatus for temporarily immobilizing a local area of tissue within a patient's body cavity. In one embodiment, the tissue immobilized is heart tissue to thereby permit surgery on a coronary vessel in that area without significant deterioration of the pumping function of the beating heart. The local area of heart tissue is immobilized to a degree sufficient to permit minimally invasive or micro-surgery on that area of the heart. The apparatus for temporarily immobilizing a local area of tissue includes a first tissue engaging member and a second tissue engaging member coupled to a spreader The spreader is operated by an actuator to selectively control the movement of the first tissue engager and the second tissue engager The method for temporarily immobilizing a local area of tissue includes controlling the spreading of the first tissue engaging member and the second tissue engaging member so a selective amount of spreading occurs.
摘要翻译：一种临时固定组织局部区域的方法和装置。特别地，本发明提供了一种临时固定患者体腔内的组织局部区域的方法和装置。在一个实施方案中，固定的组织是心脏组织，从而允许在该区域的冠状动脉血管上进行手术，而不会显着降低跳动心脏的泵送功能。心脏组织的局部区域被固定到足以允许在该区域的微创或微手术的程度。用于临时固定组织局部区域的装置包括第一组织接合构件和联接到扩展器的第二组织接合构件。扩张器由致动器操作以选择性地控制第一组织接合器和第二组织接合器的移动。该方法为了临时固定组织的局部区域，包括控制第一组织接合构件和第二组织接合构件的扩展，从而发生选择性的扩展。

3. 发明授权

US06790171B1 Method and device for transventricular mechanical circulatory support 失效
标题翻译：心室机械循环支持的方法和装置
公开(公告)号：US06790171B1
公开(公告)日：2004-09-14
申请号：US09936224
申请日：2002-03-01
申请人： Paul Frederik Gründeman , Cornelis Wilhelmus Jozef Verlaan , Cornelius Borst , Hendricus Jacobus Mansvelt Beck
发明人： Paul Frederik Gründeman , Cornelis Wilhelmus Jozef Verlaan , Cornelius Borst , Hendricus Jacobus Mansvelt Beck
IPC分类号： A61N1362
CPC分类号： A61M25/0023 , A61M1/1008 , A61M1/101 , A61M1/1024 , A61M1/1034 , A61M1/122 , A61M1/125 , A61M1/127 , A61M25/0043
摘要： Invention relates to a cannula and a screw pump for use in a mechanical circulatory support device, in particular a transventricular circulatory support device. The cannula according to the present invention comprises a tubular member made of a flexible, collapsible material having a diameter between 0.5 cm and 3 cm, preferably between 1 cm and 2.5 cm. The invention also relates to an inflatable screw pump for use in circulatory support system which comprises a flexible central drive shaft and an inflatable body having a free edge defining a spiral shaped contour around the central drive shaft and an inner edge connected to the drive shaft. The Archimedes type screw pump may be used in conjunction with the flexible cannula. The method of connecting the circulatory assist device to the heart comprises the steps of introducing the distal end of a cannula into a large systemic vein or into the right or left atrium, guiding the distal end of the cannula via the atrium to the inflow valve of the ventricle, and from there into the ventricle, guiding the distal end of the cannula from the ventricle to the ventricle outflow valve and from there into the pulmonary artery, the aorta or a side branch of the aorta and, connecting the proximal end of the cannula to a pump.
摘要翻译：本发明涉及一种用于机械循环支持装置，特别是脑室循环支持装置的套管和螺杆泵。根据本发明的套管包括由柔性的可收缩材料制成的管状构件，其直径在0.5cm和3cm之间，优选在1cm和2.5cm之间。本发明还涉及一种用于循环支持系统的可膨胀螺杆泵，其包括柔性中心驱动轴和具有围绕中心驱动轴限定螺旋形轮廓的自由边缘的可膨胀主体以及连接到驱动轴的内边缘。阿基米德型螺杆泵可与柔性套管结合使用。将循环辅助装置连接到心脏的方法包括以下步骤：将套管的远端引入大的全身静脉或右心房或左心房，将套管的远端经由心房引导到流入阀心室，并且从那里进入心室，将套管的远端从心室引导到心室流出阀，并从那里进入肺动脉，主动脉或主动脉的侧支，并连接主动脉的近端插管到泵。

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