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1. 发明申请

US20100261714A1 INHIBITORS OF HIV REPLICATION 有权
标题翻译： HIV复制抑制剂
公开(公告)号：US20100261714A1
公开(公告)日：2010-10-14
申请号：US12756276
申请日：2010-04-08
申请人： Claudio STURINO , Patrick DEROY , Martin DUPLESSIS , Paul J. EDWARDS , Anne-Marie FAUCHER , Teddy HALMOS , Clint JAMES , Jean-Eric LACOSTE , Eric MALENFANT , Joannie MINVILLE , Louis MORENCY , Sebastien MORIN , Martin TREMBLAY , Christiane YOAKIM
发明人： Claudio STURINO , Patrick DEROY , Martin DUPLESSIS , Paul J. EDWARDS , Anne-Marie FAUCHER , Teddy HALMOS , Clint JAMES , Jean-Eric LACOSTE , Eric MALENFANT , Joannie MINVILLE , Louis MORENCY , Sebastien MORIN , Martin TREMBLAY , Christiane YOAKIM
IPC分类号： A61K31/519 , C07D491/048 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D495/04 , A61K31/542 , A61P31/18 , A61K31/497
CPC分类号： C07D491/048 , C07D487/04 , C07D491/147 , C07D513/04 , C07D519/00
摘要： Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.
摘要翻译：式（I）化合物：其中R1，R2，A1，A2，A3，A4，X和Y如本文所定义，可用作HIV复制的抑制剂。

2. 发明申请

US20090143370A1 Non-nucleoside Reverse Transcriptase Inhibitors 有权
标题翻译：非核苷逆转录酶抑制剂
公开(公告)号：US20090143370A1
公开(公告)日：2009-06-04
申请号：US12364551
申请日：2009-02-03
申请人： Patrick DeROY , Anne-Marie FAUCHER , Alexandre GAGNON , Serge LANDRY , Sebastien MORIN , Jeffrey O'MEARA , Bruno SIMONEAU , Bounkham THAVONEKHAM , Christiane YOAKIM
发明人： Patrick DeROY , Anne-Marie FAUCHER , Alexandre GAGNON , Serge LANDRY , Sebastien MORIN , Jeffrey O'MEARA , Bruno SIMONEAU , Bounkham THAVONEKHAM , Christiane YOAKIM
IPC分类号： A61K31/541 , C07D257/04 , A61K31/41 , A61K31/4439 , A61P31/18 , C07D401/12 , C07D417/12
CPC分类号： C07D257/04 , A61K31/41 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/495 , A61K31/5377 , A61K31/541 , C07D231/18 , C07D233/84 , C07D249/08 , C07D249/12 , C07D277/36 , C07D285/06 , C07D285/125 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12
摘要： Compounds of formula (I): wherein Ar, X, R1, R2, R3 and R4 are as defined herein. The compounds are useful as reverse transcriptase inhibitors against wild type and single or double mutant strains of HIV.
摘要翻译：式（I）化合物：其中Ar，X，R 1，R 2，R 3和R 4如本文所定义。该化合物可用作针对野生型和单突变或双突变株的逆转录酶抑制剂。

3. 发明申请

US20120011639A1 HELMET WITH RIGID SHELL AND ADJUSTABLE LINER 有权
标题翻译： HIGMET与刚性壳和可调节衬里
公开(公告)号：US20120011639A1
公开(公告)日：2012-01-19
申请号：US12835101
申请日：2010-07-13
申请人： Pierre-Luc BEAUCHAMP , Sebastien MORIN , Philippe VALIQUETTE
发明人： Pierre-Luc BEAUCHAMP , Sebastien MORIN , Philippe VALIQUETTE
IPC分类号： A42B3/00
CPC分类号： A42B3/324
摘要： A helmet has a rigid shell and an adjustable liner connected to the shell. The liner has a plurality of pads located in the shell cavity. The pads are movable with respect to the interior shell surface between a first position near the interior shell surface and a second position further away. In some embodiments, pads are biased towards their second position and the act of the wearer inserting his head into the helmet causes the pads to move towards their first position while remaining biased against the head of the wearer to assist in causing the liner to conform to the head of the wearer. In other embodiments, constriction of the pads moves pads from their second position to their first position, for this same purpose. In other embodiments, pads having both of the aforementioned characteristics are present.
摘要翻译：头盔具有刚性外壳和连接到外壳的可调节衬垫。衬套具有位于壳腔中的多个衬垫。垫可相对于内壳表面在靠近内壳表面的第一位置和远离第二位置之间移动。在一些实施例中，垫朝向其第二位置偏置，并且佩戴者将其头部插入头盔的动作使得垫朝向其第一位置移动，同时保持偏压抵靠穿着者的头部，以帮助使衬垫符合佩戴者的头部。在其它实施例中，为了相同的目的，垫的收缩将垫从它们的第二位置移动到它们的第一位置。在其他实施例中，存在具有上述特征的焊盘。

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