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1. 发明授权

US08821828B2 Method for generating nitric oxide 有权
标题翻译：产生一氧化氮的方法
公开(公告)号：US08821828B2
公开(公告)日：2014-09-02
申请号：US13517057
申请日：2010-12-16
申请人： Rainer Hilbig , Robert Pinter , Claudia Hannelore Igney
发明人： Rainer Hilbig , Robert Pinter , Claudia Hannelore Igney
IPC分类号： C01B21/30
CPC分类号： C01B21/30 , A61K33/00 , A61M16/10 , A61M2202/0208 , A61M2202/0275
摘要： The invention relates to a method for generating nitric oxide, in particular for therapeutic applications, which comprises the steps of: guiding a process gas into a reaction chamber 3, wherein the process gas comprises nitrogen and oxygen, heating the process gas to a temperature which is sufficiently high to enable a reaction of oxygen and nitrogen to form nitric oxide, thereby forming a gas which comprises nitric oxide, and extracting the nitric oxide comprising gas from the reaction chamber 3, wherein oxygen is present in the process gas in the reaction chamber in an amount of
摘要翻译：本发明涉及一种用于产生一氧化氮的方法，特别是用于治疗应用，其包括以下步骤：将工艺气体引导到反应室3中，其中工艺气体包括氮和氧，将工艺气体加热至足够高以使氧和氮反应形成一氧化氮，从而形成包含一氧化氮的气体，并从反应室3中提取包含气体的一氧化氮，其中氧气存在于反应室中的工艺气体中其量<5体积％。

2. 发明申请

US20120258034A1 METHOD FOR GENERATING NITRIC OXIDE 有权
标题翻译：生成氮氧化物的方法
公开(公告)号：US20120258034A1
公开(公告)日：2012-10-11
申请号：US13517057
申请日：2010-12-16
申请人： Rainer Hilbig , Robert Pinter , Claudia Hannelore Igney
发明人： Rainer Hilbig , Robert Pinter , Claudia Hannelore Igney
IPC分类号： C01B21/30
CPC分类号： C01B21/30 , A61K33/00 , A61M16/10 , A61M2202/0208 , A61M2202/0275
摘要： The invention relates to a method for generating nitric oxide, in particular for therapeutic applications, which comprises the steps of: guiding a process gas into a reaction chamber 3, wherein the process gas comprises nitrogen and oxygen, heating the process gas to a temperature which is sufficiently high to enable a reaction of oxygen and nitrogen to form nitric oxide, thereby forming a gas which comprises nitric oxide, and extracting the nitric oxide comprising gas from the reaction chamber 3, wherein oxygen is present in the process gas in the reaction chamber in an amount of
摘要翻译：本发明涉及一种用于产生一氧化氮的方法，特别是用于治疗应用，其包括以下步骤：将工艺气体引导到反应室3中，其中工艺气体包括氮和氧，将工艺气体加热至足够高以使氧和氮反应形成一氧化氮，从而形成包含一氧化氮的气体，并从反应室3中提取包含气体的一氧化氮，其中氧气存在于反应室中的工艺气体中其量<5体积％。

3. 发明申请

US20130018300A1 WOUND CARE SYSTEM 审中-公开
标题翻译：创伤护理系统
公开(公告)号：US20130018300A1
公开(公告)日：2013-01-17
申请号：US13637771
申请日：2011-03-22
申请人： Claudia Hannelore Igney , Rainer Hilbig , Robert Pinter
发明人： Claudia Hannelore Igney , Rainer Hilbig , Robert Pinter
IPC分类号： A61M37/00 , A61M1/00
CPC分类号： A61M1/0088 , A61M1/0084 , A61M13/003 , A61M2202/0275
摘要： The present invention relates to a wound care system for treating a wound (14) of a patient comprising: a bathing unit (16) being designed to limit a volume (18) surrounding the wound (14) and sealing said volume (18) against the outer atmosphere, the bathing unit (16) comprising at least one gas inlet (28) and one gas outlet (30) being in fluid communication with said volume (18), a source (20) for nitric oxide being connectable to said gas inlet (28), a vacuum unit (34) being connectable to said gas outlet (30) for creating a negative pressure inside said volume (18), and a sponge (36) being placeable inside said volume (18).
摘要翻译：本发明涉及一种用于治疗患者的伤口（14）的伤口护理系统，包括：洗涤单元（16），其设计成限制围绕伤口（14）的体积（18）并将所述体积（18）密封抵抗外部气氛，包括与所述体积（18）流体连通的至少一个气体入口（28）和一个气体出口（30）的洗浴单元（16），一氧化氮源（20）可连接到所述气体入口（28），可连接到所述气体出口（30）的真空单元（34），用于在所述容积（18）内产生负压，以及海绵（36）可放置在所述容积（18）内。

4. 发明授权

US08920539B2 Method and arrangement for generating oxygen and nitric oxide 有权
标题翻译：产生氧和一氧化氮的方法和装置
公开(公告)号：US08920539B2
公开(公告)日：2014-12-30
申请号：US13822672
申请日：2011-09-14
申请人： Rainer Hilbig , Achim Gerhard Rolf Koerber , Claudia Hannelore Igney
发明人： Rainer Hilbig , Achim Gerhard Rolf Koerber , Claudia Hannelore Igney
IPC分类号： B01D53/22 , B01D63/00 , C01B13/02 , A61K33/00 , C01B21/24
CPC分类号： A61K33/00 , B01D63/00 , C01B13/0251 , C01B21/24 , A61K2300/00
摘要： The invention relates to a Method of generating oxygen and nitric oxide. The method comprises the steps of: guiding an oxygen comprising gas to a primary side of a dense membrane (42), heating the membrane (42) to a temperature at which it is permeable for oxygen, creating a pressure difference between the primary side of the membrane (42) and a secondary side of the membrane (42), wherein a stream of oxygen is generated at the secondary side of the membrane (42) and a stream of oxygen depleted gas is generated at the primary side of the membrane (42). The method according to the invention further comprises the steps of: providing a flow of nitrous oxide comprising gas and heating the nitrous oxide comprising gas to a temperature at which nitric oxide is generated. Thereby, according to the invention, heat generated in the process of operating the membrane is used. According to the invention it is possible to generate both oxygen and nitric oxide in one device making use of several synergistic effects, thus being energy saving.
摘要翻译：本发明涉及产生氧和一氧化氮的方法。该方法包括以下步骤：将含氧气体引导到致密膜（42）的初级侧，将膜（42）加热至可渗透氧气的温度，从而在第膜（42）和膜（42）的次级侧，其中在膜（42）的次级侧产生氧气流，并且在膜的初级侧产生贫氧气体流（ 42）。根据本发明的方法还包括以下步骤：提供包含气体的一氧化二氮流并将包含一氧化二氮的气体加热至产生一氧化氮的温度。因此，根据本发明，使用在操作膜的过程中产生的热量。根据本发明，可以在一个使用几种协同效应的装置中产生氧和一氧化氮，从而节能。

5. 发明申请

US20150053544A1 METHOD AND ARRANGEMENT FOR GENERATING NITRIC OXIDE 有权
标题翻译：生成氮氧化物的方法和装置
公开(公告)号：US20150053544A1
公开(公告)日：2015-02-26
申请号：US13988786
申请日：2011-11-28
申请人： Claudia Hannelore Igney , Rainer Hilbig , Achim Gerhard Rolf Koerber
发明人： Claudia Hannelore Igney , Rainer Hilbig , Achim Gerhard Rolf Koerber
IPC分类号： B01J19/12
CPC分类号： B01J19/12 , A61K33/00 , A61M16/10 , A61M2016/1035 , A61M2202/0275 , B01J2219/0877 , B01J2219/12 , C01B21/24
摘要： The present invention relates to a method for generating nitric oxide, which comprises the steps of: providing a precursor solution comprising a nitric oxide precursor in a first reservoir (12), guiding the precursor solution through a reaction chamber (16), thereby subjecting the precursor solution to radiation to generate nitric oxide, guiding the generated nitric oxide out of the reaction chamber (16) by a stream of carrier gas, and guiding the reacted solution into a second reservoir (14). The method according to the invention provides a method of generating nitric oxide, or a flow of nitric oxide comprising gas, in which the concentration of the nitric oxide may be kept especially constant. Also claimed is an apparatus for generating nitric oxide comprising reservoirs for the precursor solution and the reacted solution and a reaction chamber.
摘要翻译：本发明涉及产生一氧化氮的方法，其包括以下步骤：在第一储存器（12）中提供包含一氧化氮前体的前体溶液，引导前体溶液通过反应室（16），从而使前体溶液以产生一氧化氮，通过载气流将产生的一氧化氮引导出反应室（16），并将反应的溶液引导到第二储存器（14）中。根据本发明的方法提供了产生一氧化氮或包含气体的一氧化氮的流动的方法，其中一氧化氮的浓度可以保持特别恒定。还要求的是用于产生一氧化氮的装置，其包括用于前体溶液和反应溶液和反应室的储存器。

6. 发明申请

US20130327329A1 METHOD AND ARRANGEMENT FOR GENERATING A GAS STREAM COMPRISING NITRIC OXIDE 审中-公开
标题翻译：用于产生包含氮氧化物的气体流的方法和装置
公开(公告)号：US20130327329A1
公开(公告)日：2013-12-12
申请号：US13984356
申请日：2012-02-16
申请人： Claudia Hannelore Igney , Achim Koerber , Rainer Hilbig
发明人： Claudia Hannelore Igney , Achim Koerber , Rainer Hilbig
IPC分类号： A61M16/12
CPC分类号： A61M16/12 , A61M16/00 , A61M2202/0208 , A61M2202/0275
摘要： The invention relates to the field of nitric oxide generation. The present invention particularly relates to a method for generating a stream of gas, the gas comprising oxygen and nitric oxide. According to the invention, an intermittent stream of oxygen comprising gas having at least one gap is provided, in which gap a defined pulse of nitric oxide comprising gas is provided. The pulse of nitric oxide comprising gas is embedded in a first pulse of inert gas being provided before the pulse of nitric oxide comprising gas and a second pulse of inert gas being provided after the pulse of nitric oxide comprising gas, the first pulse of inert gas and the second pulse of inert gas being provided in the gap of the intermittent stream of oxygen comprising gas. The method according to the invention reduces the danger of toxic compounds to be formed in the generated gas stream and furthermore provides a method being usable for therapeutic applications independent from the breathing cycle of a patient.
摘要翻译：本发明涉及一氧化氮生成领域。本发明特别涉及一种产生气流的方法，所述气体包括氧和一氧化氮。根据本发明，提供了包含具有至少一个间隙的气体的间歇性氧气流，其中提供了包含气体的一定氧化物脉冲。在包含气体的一氧化氮脉冲之后，在包含气体的一氧化氮的脉冲之后，提供包含气体的一氧化氮的脉冲，该惰性气体的第一脉冲是在包含气体的一氧化氮的脉冲之前提供的，第一脉冲的惰性气体脉冲并且第二脉冲的惰性气体设置在包含气体的间歇性氧气流的间隙中。根据本发明的方法降低了在产生的气流中形成的有毒化合物的危险性，并且还提供了可独立于患者呼吸循环的治疗应用的方法。

7. 发明授权

US09776161B2 Method and arrangement for generating nitric oxide 有权
公开(公告)号：US09776161B2
公开(公告)日：2017-10-03
申请号：US13988786
申请日：2011-11-28
申请人： Claudia Hannelore Igney , Rainer Hilbig , Achim Gerhard Rolf Koerber
发明人： Claudia Hannelore Igney , Rainer Hilbig , Achim Gerhard Rolf Koerber
IPC分类号： B01J19/12 , C01B21/24 , A61M16/10 , A61K33/00
CPC分类号： B01J19/12 , A61K33/00 , A61M16/10 , A61M2016/1035 , A61M2202/0275 , B01J2219/0877 , B01J2219/12 , C01B21/24
摘要： The present invention relates to a method for generating nitric oxide, which comprises the steps of: providing a precursor solution comprising a nitric oxide precursor in a first reservoir (12), guiding the precursor solution through a reaction chamber (16), thereby subjecting the precursor solution to radiation to generate nitric oxide, guiding the generated nitric oxide out of the reaction chamber (16) by a stream of carrier gas, and guiding the reacted solution into a second reservoir (14). The method according to the invention provides a method of generating nitric oxide, or a flow of nitric oxide comprising gas, in which the concentration of the nitric oxide may be kept especially constant. Also claimed is an apparatus for generating nitric oxide comprising reservoirs for the precursor solution and the reacted solution and a reaction chamber.

8. 发明申请

US20130177657A1 METHOD AND ARRANGEMENT FOR GENERATING OXYGEN AND NITRIC OXIDE 有权
标题翻译：生成氧和氮氧化物的方法和装置
公开(公告)号：US20130177657A1
公开(公告)日：2013-07-11
申请号：US13822672
申请日：2011-09-14
申请人： Rainer Hilbig , Achim Gerhard Rolf Koerber , Claudia Hannelore Igney
发明人： Rainer Hilbig , Achim Gerhard Rolf Koerber , Claudia Hannelore Igney
IPC分类号： A61K33/00 , B01D63/00
CPC分类号： A61K33/00 , B01D63/00 , C01B13/0251 , C01B21/24 , A61K2300/00
摘要： The invention relates to a Method of generating oxygen and nitric oxide. The method comprises the steps of: guiding an oxygen comprising gas to a primary side of a dense membrane (42), heating the membrane (42) to a temperature at which it is permeable for oxygen, creating a pressure difference between the primary side of the membrane (42) and a secondary side of the membrane (42), wherein a stream of oxygen is generated at the secondary side of the membrane (42) and a stream of oxygen depleted gas is generated at the primary side of the membrane (42). The method according to the invention further comprises the steps of: providing a flow of nitrous oxide comprising gas and heating the nitrous oxide comprising gas to a temperature at which nitric oxide is generated. Thereby, according to the invention, heat generated in the process of operating the membrane is used. According to the invention it is possible to generate both oxygen and nitric oxide in one device making use of several synergistic effects, thus being energy saving.
摘要翻译：本发明涉及产生氧和一氧化氮的方法。该方法包括以下步骤：将含氧气体引导到致密膜（42）的初级侧，将膜（42）加热至可渗透氧气的温度，从而在第膜（42）和膜（42）的次级侧，其中在膜（42）的次级侧产生氧气流，并且在膜的初级侧产生贫氧气体流（ 42）。根据本发明的方法还包括以下步骤：提供包含气体的一氧化二氮流并将包含一氧化二氮的气体加热至产生一氧化氮的温度。因此，根据本发明，使用在操作膜的过程中产生的热量。根据本发明，可以在一个使用几种协同效应的装置中产生氧和一氧化氮，从而节能。

9. 发明申请

US20090306524A1 SENSOR FOR DETECTING THE PASSING OF A PULSE WAVE FROM A SUBJECT'S ARTERIAL SYSTEM 审中-公开
标题翻译：用于检测来自主体动脉系统的脉冲波的传感器
公开(公告)号：US20090306524A1
公开(公告)日：2009-12-10
申请号：US12375579
申请日：2007-07-11
申请人： Jens Muhlsteff , Claudia Hannelore Igney , Jeroen Adrianus Joannes Thijs , Robert Pinter
发明人： Jens Muhlsteff , Claudia Hannelore Igney , Jeroen Adrianus Joannes Thijs , Robert Pinter
IPC分类号： A61B5/021 , A61B5/024
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/0535
摘要： In order to provide an easy-to-use technique for measuring blood pressure and/or other vital signs of a subject, a sensor for detecting the passing of a pulse wave from a subject's arterial system is suggested, the sensor being adapted to be located at a sensing position on the exterior of the subject's body, characterized in that the sensor comprises a number of electrical coils for generating an inductive coupling to the subject's body in a way that the properties of said inductive coupling change if a pulse wave passes a screened volume underneath the sensing position, and a circuit connected to the number of electrical coils, said circuit being adapted to detect said property changes of the inductive coupling.
摘要翻译：为了提供用于测量受试者的血压和/或其他生命体征的易于使用的技术，建议用于检测来自受试者的动脉系统的脉搏波的传递的传感器，所述传感器适于位于在被检体的外部的感测位置处，其特征在于，所述传感器包括多个电线圈，用于以如下方式产生电感耦合：使得所述电感耦合的特性如果脉波通过屏蔽感测位置下方的体积以及连接到电气线圈数量的电路，所述电路适于检测电感耦合的所述属性变化。

10. 发明授权

US08125220B2 Magnetic induction tomography system and method 有权
标题翻译：磁感应层析成像系统及方法
公开(公告)号：US08125220B2
公开(公告)日：2012-02-28
申请号：US12097529
申请日：2006-12-14
申请人： Claudia Hannelore Igney , Robert Pinter , Olaf Such
发明人： Claudia Hannelore Igney , Robert Pinter , Olaf Such
IPC分类号： G01B7/14 , G01R33/12 , G01N27/82
CPC分类号： G01V3/104 , A61B5/0522 , A61B5/0536
摘要： A magnetic induction tomography system and method for studying the electromagnetic properties of an object includes generator coils adapted for generating a primary magnetic field, and sensor coils adapted for sensing a secondary magnetic field. Actuators provide relative movement between the generator coils and/or the sensor coils on the one hand and the object to be studied on the other hand.
摘要翻译：用于研究物体的电磁特性的磁感应断层摄影系统和方法包括适于产生初级磁场的发生器线圈和适于感测次级磁场的传感器线圈。致动器一方面提供发电机线圈和/或传感器线圈与另一方面要研究的物体之间的相对运动。

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