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    • 5. 发明申请
    • OPHTHALMOLOGIC BIOMETRIC OR IMAGE GENERATING SYSTEM AND METHOD FOR DETECTION AND EVALUATION OF MEASURED DATA
    • 用于检测和评估测量数据的眼科生物学或图像生成系统和方法
    • US20110069279A1
    • 2011-03-24
    • US12886155
    • 2010-09-20
    • Martin HackerThomas PabstRalf EbersbachGerard AntkowiakWilfried BissmannMatthias Reich
    • Martin HackerThomas PabstRalf EbersbachGerard AntkowiakWilfried BissmannMatthias Reich
    • A61B3/10
    • A61B3/102
    • An ophthalmological biometric or image-producing system and method for detection and analysis of measurement data including a measurement arrangement with an illumination unit for illuminating the eye with at least one measurement beam, a signal detection unit for the detection of the light portions scattered or reflected back from the eye, a central control unit with an output unit, and a pattern generating unit which includes an optical scan unit, a control unit as well as a position sensor for measuring the realized deflections of the optical scan unit, whereby control unit, optical scan unit and position sensor can form a control circuit. Thereby, the position sensor, except for the connection within the possible control circuit, includes a connection to a unit of the measurement arrangement for optimizing measurement value logging or to the central control unit for correcting the biometric measurements or tomograms.
    • 一种用于检测和分析测量数据的眼科生物测定或图像产生系统和方法,所述测量数据包括具有用于利用至少一个测量光束照射眼睛的照明单元的测量装置,用于检测散射或反射的光部分的信号检测单元 从眼睛回来的具有输出单元的中央控制单元,以及包括光学扫描单元,控制单元以及用于测量所实现的光学扫描单元的偏转的位置传感器的图案生成单元,由此控制单元, 光学扫描单元和位置传感器可以形成一个控制电路。 由此,除了可能的控制电路内的连接之外,位置传感器包括与用于优化测量值记录的测量装置的单元的连接或者用于校正生物测量或断层图像的中央控制单元的连接。
    • 9. 发明授权
    • Process for the manufacture of α-tocopheryl acetate
    • 制备α-生育酚乙酸酯的方法
    • US07135580B2
    • 2006-11-14
    • US10541360
    • 2003-12-22
    • Werner BonrathClaus DittelLisa GiraudiThomas NetscherThomas Pabst
    • Werner BonrathClaus DittelLisa GiraudiThomas NetscherThomas Pabst
    • C07D311/72
    • C07D311/72
    • The present invention is concerned with a novel process for the manufacture of α-tocopheryl acetate which comprises reacting 2,3,6-trimethylhydroquinone-1-acetate with a compound selected from the group consisting of phytol (formula IV with R═OH), iso-phytol (formula III with R═OH), and (iso) phytol derivatives represented by the following formulae III and IV with R═C2-to C5-alkonoyloxy, benzoyloxy, mesyloxy, bezenesul-fonyloxy or tosyloxy, (IV) in the presence of a catalyst of the formula Mn+(R1SO3−)n, wherein Mn+ is a silver, copper, gallium, hafnium or rare earth metal cation, n is the valence of the cation Mn+, and R1 is fluorine, C1-8-perfluoroalkyl or perfluoroaryl, and, if required, cyclizing any 3-phytyl-2,5,6-trimethylhydroquinone-1-acetate or a double bond isomer thereof obtained as an intermediate reaction product, to produce α-tocopheryl acetate. In the catalyst Mn+ is preferably Ag+, Cu+, Ga3+, Sc3+, Lu3+, Ho3+, Tm3+, Yb3+ or Hf4+.
    • 本发明涉及制备乙酸α-生育酚酯的新方法,其包括使2,3,6-三甲基氢醌-1-乙酸酯与选自植醇(式IV与R-OH)的化合物反应, 异山嵛醇(具有R-OH的式III)和由下式III和IV表示的(iso)植醇醇衍生物,其具有至少2个至5个C 5 - 烷酰氧基, 苯甲酰氧基,甲磺酰氧基,枯烯二烯基氧基或甲苯磺酰氧基,(Ⅳ)在式M n n n a a a>>>>>>>>>>>>>>>>>>>>>>>>>> 其中M + N +是银,铜,镓,铪或稀土金属阳离子,n是阳离子的化合价 M + N +,R 1是氟,C 1-8 - 全氟烷基或全氟芳基,如果需要,可以将任何3-植酰基 - 获得的作为中间体反应产物的2,5,6-三甲基氢醌-1-乙酸酯或其双键异构体,以产生乙酸α-生育酚酯。 在催化剂中,N + +优选为Ag +,Cu +,Ga 3+,Sc 3 或+ 3+,3+,3 +,3 +,3 +,3 + Hf 4+。