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    • 2. 再颁专利
    • Modulators of dopamine neurotransmission
    • 多巴胺神经传递调节剂
    • USRE41315E1
    • 2010-05-04
    • US11904013
    • 2000-12-22
    • Clas SonessonBengt AnderssonIngela Marianne SvanSusanna WatersNicholas WatersJoakim Tedroff
    • Clas SonessonBengt AnderssonSusanna WatersNicholas WatersJoakim Tedroff
    • C07D211/04A61K31/445
    • C07D295/073C07D211/18C07D241/04C07D295/096
    • New 3-substituted 4-(phenyl-N-alkyl)-piperazine and 4-(phenyl-N-alkyl)-piperidine compounds of Formula (1) wherein X is N, CH, or C, however X may only be C when the compound comprises a double bind at the dotted line; R1 is CF3, OSO2CF3, OSO2CH3, SOR7, SO2R7, COR7, CN, OR3, NO2, CONHR3, 3-thiophene, 2-thiophene, 3-furane, 2-furane, F, Cl, Br, or I; R2 is F, Cl, Br, I, CN, CF3, CH3, OCH3, OH, and NH2; R3 and R4 are independently H or a C1-C4 alkyl; R5 is a C1-C4 alkyl, an allyl, CH2SCH3, CH2CH2OCH3, CH2CH2CH2F, CH2CF3, 3,3,3-trifluoropropyl, 4,4,4-trifluorobutyl, or —(CH2)R6; R6 is a C3-C6 cycloalkyl, 2-tetrahydrofurane, or 3-tetra-hydrofurane; R7 is a C1-C3 alkyl, CF3, or N(R4)2, and pharmaceutically acceptable salts thereof are disclosed. Also pharmaceutical compositions comprising the above compounds and methods wherein the above compounds are used for treatment of disorders in the central nervous system are disclosed.
    • 新的3-取代的4-(苯基-N-烷基) - 哌嗪和式(1)的4​​-(苯基-N-烷基) - 哌啶化合物,其中X是N,CH或C,但是X可以仅为C 该化合物在虚线处包含双键; R1是CF3,OSO2CF3,OSO2CH3,SOR7,SO2R7,COR7,CN,OR3,NO2,CONHR3,3噻吩,2-噻吩,3-呋喃,2-呋喃,F,Cl,Br或I; R2是F,Cl,Br,I,CN,CF3,CH3,OCH3,OH和NH2; R 3和R 4独立地为H或C 1 -C 4烷基; R5是C1-C4烷基,烯丙基,CH2SCH3,CH2CH2OCH3,CH2CH2CH2F,CH2CF3,3,3,3-三氟丙基,4,4,4-三氟丁基或 - (CH2)R6; R6是C3-C6环烷基,2-四氢呋喃或3-四氢呋喃; R7是C1-C3烷基,CF3或N(R4)2,并且其药学上可接受的盐被公开。 还公开了包含上述化合物的药物组合物和其中上述化合物用于治疗中枢神经系统疾病的方法。
    • 8. 发明授权
    • Procedure and device for the control of a radar unit
    • 用于控制雷达装置的程序和装置
    • US5907301A
    • 1999-05-25
    • US008624
    • 1998-01-16
    • Bengt Andersson
    • Bengt Andersson
    • G01S7/03G01S7/282G01S13/10G01S13/18
    • G01S7/282G01S13/106G01S13/18G01S7/03
    • A procedure and a device for controlling, in a radar unit for the measurement of target data, the transmission of radar pulses and the reception of target echoes originating from the transmitted radar pulses, in such a way that the performance of the radar unit increases, in order thereby to gain a longer range during a period of time. The period of time is preferably repeated continually. The period of time is divided into a first and a second partial period of time where the first and the second partial periods of time are each at least twice as long as a pulse repetition interval which is used during the first partial period of time. During the first partial period of time the radar unit is controlled so that it transmits radar pulses for the measurement of target data with a higher energy content than what is possible in a steady state. The control is carried out in such a way that the amount of transmitted energy of the radar unit during the period of time is at the most the possible energy transmission of the radar unit in a steady state during a corresponding period of time. There is thereby obtained a more efficient signal integration by means of the signal integration of the target echoes that originate from the radar unit being concentrated during the first partial period of time. The radar unit is also controlled so that it does not transmit radar pulses for the measurement of target data during the second partial period of time.
    • 一种用于在用于测量目标数据的雷达单元中以雷达单元的性能增加的方式控制雷达脉冲的传输和从发射的雷达脉冲发射的目标回波的接收的过程和装置, 从而在一段时间内获得更长的范围。 该时间段优选连续重复。 该时间段被分为第一和第二部分时间段,其中第一和第二部分时间段各自是在第一部分时间段期间使用的脉冲重复间隔的至少两倍。 在第一部分时间段期间,雷达单元被控制,使得其以比在稳定状态下可能的更高的能量内容传输用于测量目标数据的雷达脉冲。 以这样的方式进行控制,使得雷达单元在一段时间内的发射能量在相应的时间段内处于稳定状态下雷达单元的可能能量传输的最多。 由此,通过来自在第一部分时间段内集中的雷达单元的目标回波的信号积分,获得了更有效的信号积分。 雷达单元也被控制,使得其在第二部分时间段内不传送用于测量目标数据的雷达脉冲。