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    • 2. 发明申请
    • Golf club head having a brazed striking plate
    • 高尔夫球杆头有一个钎焊的打击板
    • US20050261081A1
    • 2005-11-24
    • US10849514
    • 2004-05-20
    • Chan-Tung ChenChun-Yung Huang
    • Chan-Tung ChenChun-Yung Huang
    • A63B53/04
    • A63B53/047A63B53/0466A63B2053/0416
    • A golf club head includes a casing with a front open end to which a striking plate is attached through a layer of brazing material that is formed between a rear surface of the striking plate and a frontmost end face of the casing. One of the striking plate and the front open end of the casing has an extension part which projects outward in a direction away from the opening. The extension part forms a shoulder with one of the first and second outer peripheral faces. During a brazing process, the brazing material is positioned against the shoulder externally of a clearance between the rear surface and the frontmost end face and is then melted to flow into the clearance through a capillary action.
    • 高尔夫球杆头包括具有前开口端的壳体,撞击板通过形成在打击板的后表面和壳体的最前端面之间的钎焊材料层附接到该外壳。 壳体的打击板和前开口端之一具有沿远离开口的方向向外突出的延伸部分。 延伸部分形成具有第一和第二外周面之一的肩部。 在钎焊过程中,钎焊材料在后表面和最前端面之间的间隙的外侧抵靠肩部定位,然后通过毛细管作用熔化以流入间隙。
    • 7. 发明申请
    • PROCESS TO PRODUCE FIBRILLAR PROTEINS AND METHOD OF TREATMENT USING FIBRILLAR PROTEINS
    • 生产纤维蛋白的方法和使用纤维蛋白的治疗方法
    • US20120316117A1
    • 2012-12-13
    • US13572652
    • 2012-08-12
    • Shu-Mei LiangChun-Yung HuangChi-Ming Liang
    • Shu-Mei LiangChun-Yung HuangChi-Ming Liang
    • A61K38/38A61P35/00
    • A61K31/7088A61K38/162A61K38/38A61K38/39A61K39/39A61K2039/55516
    • A method for inhibiting survival of cancer cells in a subject is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of fibrillar albumin. The preparation of the fibrillar albumin comprises: (i) forming a solution comprising an isolated and/or purified globular albumin; (ii) adding a detergent to the solution containing the isolated and/or purified globular albumin, wherein the detergent is one selected from the group consisting of sodium dodecyl sulfate (SDS) and n-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; (iii) applying the solution to a molecular sizing column with a pore size that permits separation of a protein with a molecular weight of at least about 70 kDa so as to promote column-induced formation of the fibrillar albumin from the isolated and/or purified globular albumin; and (iv) eluting the fibrillar albumin from the column, wherein the eluted albumin has a fibrillar structure.
    • 公开了抑制受试者中癌细胞存活的方法。 该方法包括向有需要的受试者施用治疗有效量的原纤维白蛋白。 纤维状白蛋白的制备包括:(i)形成包含分离和/或纯化的球状白蛋白的溶液; (ii)向含有分离和/或纯化的球状白蛋白的溶液中加入洗涤剂,其中洗涤剂选自十二烷基硫酸钠(SDS)和正十四烷基-N,N-二甲基-3-氨基 -1-丙磺酸盐; (iii)将溶液施加到具有允许分离至少约70kDa的分子量的蛋白质的孔径的分子筛分柱,以便促进来自分离和/或纯化的柱状诱导的纤维状白蛋白的形成 球状白蛋白 和(iv)从柱中洗脱纤维状白蛋白,其中洗脱的白蛋白具有纤维状结构。
    • 8. 发明授权
    • Process to produce fibrillar proteins
    • 生产纤维蛋白的方法
    • US08268974B2
    • 2012-09-18
    • US12082634
    • 2008-04-11
    • Shu-Mei LiangChun-Yung HuangYen-Po ChenChi-Ming Liang
    • Shu-Mei LiangChun-Yung HuangYen-Po ChenChi-Ming Liang
    • A61K38/00A61K45/00C07K1/00C07K14/00
    • A61K31/7088A61K38/162A61K38/38A61K38/39A61K39/39A61K2039/55516
    • A method for changing a globular protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a detergent to the solution containing the globular protein, applying the solution to a molecular sizing column with a pore size of at least 70 kDa and eluting with a solution containing detergent. A method for changing an unfolded protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a urea to the solution to unfold the globular protein, applying the solution to a molecular sizing column and eluting with a solution containing detergent. A method for treating cancer comprising the steps of providing a protein, changing the protein into a fibrillar structure, and administering a therapeutically effective amount of the fibrillar structure protein to a patient in need thereof. A method for producing a vaccine adjuvant or antigen adjuvant comprising the steps of providing a protein, and changing the protein into a fibrillar structure.
    • 一种将球状蛋白结构变为纤维状蛋白结构的方法。 该方法包括以下步骤:提供球状蛋白质,形成含有球状蛋白质的溶液,向含有球状蛋白质的溶液中加入洗涤剂,将溶液施加到孔径至少为70kDa的分子筛分柱上,并用 含有洗涤剂的溶液。 将展开的蛋白质结构改变成纤维蛋白结构的方法。 该方法包括以下步骤:提供球状蛋白质,形成含有球状蛋白质的溶液,向溶液中加入尿素以展开球状蛋白质,将溶液施加到分子筛分柱上并用含有洗涤剂的溶液洗脱。 一种治疗癌症的方法,包括提供蛋白质,将蛋白质改变成纤维结构,以及向有需要的患者施用治疗有效量的纤维结构蛋白的步骤。 一种用于生产疫苗佐剂或抗原佐剂的方法,包括提供蛋白质并将蛋白质变成纤维结构的步骤。
    • 10. 发明授权
    • Manufacturing method for a wax pattern for making a golf club head
    • 用于制造高尔夫球杆头的蜡模的制造方法
    • US07152656B2
    • 2006-12-26
    • US11236498
    • 2005-09-28
    • Chun-Yung HuangChun-Yu Chen
    • Chun-Yung HuangChun-Yu Chen
    • B22C7/02B22C9/04
    • B22C7/02B22C9/108
    • A manufacturing method for a hybrid one-piece design of a wax pattern of a golf club head includes the steps of: prefabricating a first wax pattern in a first molding assembly, the first wax pattern having a connecting portion; inserting the first wax pattern into a first mold cavity of a second molding assembly which has a configuration substantially corresponding to that of a first component of the golf club head; filling liquid wax into a second mold cavity of the second molding assembly which has a configuration substantially corresponding to that of a second component of the golf club head; and cooling the liquid wax in the second mold cavity to form a second wax pattern joined to the connecting portion of the first wax pattern.
    • 一种用于高尔夫球杆头蜡模的混合一件式设计的制造方法,包括以下步骤:在第一模制组件中预制第一蜡图案,所述第一蜡图案具有连接部分; 将第一蜡图案插入第二模制组件的第一模腔中,该第二模具组件具有基本对应于高尔夫球杆头的第一部件的构型; 将液体蜡填充到第二模制组件的第二模腔中,其具有基本上对应于高尔夫球杆头的第二部件的构造的构造; 以及冷却第二模腔中的液体蜡以形成与第一蜡图案的连接部分相连接的第二蜡图案。