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1. 发明授权

US08142427B2 Invasive ablation probe with non-coring distal tip 有权
标题翻译：侵入性消融探针与非取芯远端
公开(公告)号：US08142427B2
公开(公告)日：2012-03-27
申请号：US10831244
申请日：2004-04-23
申请人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
发明人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432
摘要： An invasive medical device for delivery radio frequency energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a biocompatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position. By way of examples, the sealing member may be carried on a distal end of the deployment member, or on a separately movable deployment member, or frictionally fit in the cannula distal opening.
摘要翻译：用于将射频能量传送到目标组织区域的侵入性医疗装置包括具有与远端开口连通的内腔的细长输送套管。展开构件在内腔中定位和纵向移动。电极元件的阵列固定到展开构件的远端，展开构件可从电子元件位于内腔内的输送位置移动到展开位置，电极元件向远侧延伸的套管远端开口。当展开构件处于输送位置时，由足够刚性以穿透实体组织的生物相容性材料形成的密封构件部分延伸并且基本上密封远端插管开口。作为示例，密封构件可以承载在展开构件的远端上，或者在可单独移动的展开构件上承载，或摩擦地配合在套管远侧开口中。

2. 发明申请

US20120220994A1 INVASIVE ABLATION PROBE WITH NON-CORING DISTAL TIP 失效
标题翻译：具有非线性距离提示的入侵消除探测
公开(公告)号：US20120220994A1
公开(公告)日：2012-08-30
申请号：US13423205
申请日：2012-03-17
申请人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
发明人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432
摘要： A medical device for delivering RF energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a bio-compatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position.
摘要翻译：用于将RF能量递送到目标组织区域的医疗装置包括具有与远端开口连通的内腔的细长输送套管。展开构件在内腔中定位和纵向移动。电极元件的阵列固定到展开构件的远端，展开构件可从电子元件位于内腔内的输送位置移动到展开位置，电极元件向远侧延伸的套管远端开口。当展开构件处于输送位置时，由足够刚性以穿透实体组织的生物相容性材料形成的密封构件部分延伸并且基本上密封远侧插管开口。

3. 发明授权

US08632538B2 Invasive ablation probe with non-coring distal tip 失效
标题翻译：侵入性消融探针与非取芯远端
公开(公告)号：US08632538B2
公开(公告)日：2014-01-21
申请号：US13423205
申请日：2012-03-17
申请人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
发明人： Christopher Pearson , Robert Garabedian , Robert F. Rioux
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/143 , A61B2018/1432
摘要： A medical device for delivering RF energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a bio-compatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position.
摘要翻译：用于将RF能量递送到目标组织区域的医疗装置包括具有与远端开口连通的内腔的细长输送套管。展开构件在内腔中定位和纵向移动。电极元件的阵列固定到展开构件的远端，展开构件可从电子元件位于内腔内的输送位置移动到展开位置，电极元件向远侧延伸的套管远端开口。当展开构件处于输送位置时，由足够刚性以穿透实体组织的生物相容性材料形成的密封构件部分延伸并且基本上密封远侧插管开口。

4. 发明授权

US08216235B2 Liquid infusion apparatus for radiofrequency tissue ablation 有权
标题翻译：液体输液装置用于射频组织消融
公开(公告)号：US08216235B2
公开(公告)日：2012-07-10
申请号：US11944257
申请日：2007-11-21
申请人： Robert F. Rioux , Robert Garabedian , Christopher Pearson
发明人： Robert F. Rioux , Robert Garabedian , Christopher Pearson
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00065 , A61B2018/1472 , A61B2018/1475
摘要： An apparatus for delivering electrical energy includes a tubular member having a pair of opposing members extendable from the distal end of the tubular member, the opposing members being directable towards one another for engaging tissue between inner surfaces of the opposing members, the opposing members having one or more electrodes for delivering electrical energy to tissue engaged between the opposing members. One or more hollow needles extend from an inner surface of at least one opposing member, the hollow needles configured to deliver conductive fluid from a lumen into tissue penetrated by the needles.
摘要翻译：一种用于传递电能的装置包括管状构件，该管状构件具有从管状构件的远端延伸的一对相对构件，相对构件可相对于彼此指向，用于在相对构件的内表面之间接合组织，相对构件具有一个或更多的电极，用于将电能传递到在相对构件之间接合的组织。一个或多个中空针从至少一个相对构件的内表面延伸，所述中空针被配置成将导管流体从内腔输送到被针穿透的组织中。

5. 发明申请

US20080140065A1 SYSTEMS AND METHODS FOR PERFORMING SIMULTANEOUS ABLATION 失效
标题翻译：同时进行同步排除的系统和方法
公开(公告)号：US20080140065A1
公开(公告)日：2008-06-12
申请号：US12033262
申请日：2008-02-19
申请人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.
摘要翻译：用于治疗组织的系统包括第一和第二消融装置，每个消融装置包括多个线电极并且并联耦合到发生器。在一个实施例中，发生器包括彼此并联耦合的第一和第二端子，并且第一和第二消融装置分别连接到第一和第二端子。或者，第一和第二消融装置使用“Y”电缆耦合到发生器的单个端子。接地电极与第一和第二消融装置相对的发生器耦合，用于单极操作。第一和第二电极阵列插入在组织区域内彼此相邻的第一和第二位置。能量同时传送到第一和第二阵列以在第一和第二部位产生损伤，优选地使得第一和第二病变重叠。

6. 发明授权

US07354436B2 Systems and methods for performing simultaneous ablation 有权
标题翻译：同时进行消融的系统和方法
公开(公告)号：US07354436B2
公开(公告)日：2008-04-08
申请号：US11238403
申请日：2005-09-28
申请人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.
摘要翻译：用于治疗组织的系统包括第一和第二消融装置，每个消融装置包括多个线电极并且并联耦合到发生器。在一个实施例中，发生器包括彼此并联耦合的第一和第二端子，并且第一和第二消融装置分别连接到第一和第二端子。或者，第一和第二消融装置使用“Y”电缆耦合到发生器的单个端子。接地电极与第一和第二消融装置相对的发生器耦合，用于单极操作。第一和第二电极阵列插入在组织区域内彼此相邻的第一和第二位置。能量同时传送到第一和第二阵列以在第一和第二部位产生损伤，优选地使得第一和第二病变重叠。

7. 发明授权

US07174217B2 Apparatus and methods for assisting ablation of tissue using magnetic beads 有权
标题翻译：使用磁珠辅助组织消融的装置和方法
公开(公告)号：US07174217B2
公开(公告)日：2007-02-06
申请号：US11224864
申请日：2005-09-12
申请人： Robert F. Rioux , Robert Garabedian
发明人： Robert F. Rioux , Robert Garabedian
IPC分类号： A61F7/00
CPC分类号： A61N1/406 , A61N2/02
摘要： A system for treating tissue includes a source of conductive and/or magnetic beads, a first member, e.g., a catheter or cannula, coupled to the source of magnetic beads, and a second member, e.g., a catheter or cannula, carrying a magnet on its distal end. The system is used for ablating or otherwise treating tissue within a target tissue region including a blood vessel contacting or passing therethrough. Magnetic beads are introduced into the target tissue region, e.g., using the first member, and a magnetic field is generated within the target tissue region, e.g., using the second member, to cause the magnetic beads to migrate towards a wall of the vessel. Energy is delivered into the target tissue region, e.g., to heat tissue therein, and the magnetic beads may attenuate or enhance treatment of tissue adjacent to the vessel.
摘要翻译：用于治疗组织的系统包括导电和/或磁珠的源，耦合到磁珠源的第一构件，例如导管或插管，以及携带磁体的第二构件，例如导管或套管在其远端。该系统用于烧蚀或以其他方式处理包括接触或穿过其中的血管的靶组织区域内的组织。将磁珠引入目标组织区域，例如使用第一构件，并且例如使用第二构件在目标组织区域内产生磁场，使磁珠朝向容器的壁迁移。能量被递送到目标组织区域中，例如以加热其中的组织，并且磁珠可以减弱或增强对与血管相邻的组织的治疗。

8. 发明授权

US06958064B2 Systems and methods for performing simultaneous ablation 有权
标题翻译：同时进行消融的系统和方法
公开(公告)号：US06958064B2
公开(公告)日：2005-10-25
申请号：US10713357
申请日：2003-11-14
申请人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.
摘要翻译：用于治疗组织的系统包括第一和第二消融装置，每个消融装置包括多个线电极并且并联耦合到发生器。在一个实施例中，发生器包括彼此并联耦合的第一和第二端子，并且第一和第二消融装置分别连接到第一和第二端子。或者，第一和第二消融装置使用“Y”电缆耦合到发生器的单个端子。接地电极与第一和第二消融装置相对的发生器耦合，用于单极操作。第一和第二电极阵列插入在组织区域内彼此相邻的第一和第二位置。能量同时传送到第一和第二阵列以在第一和第二部位产生损伤，优选地使得第一和第二病变重叠。

9. 发明申请

US20090240247A1 SYSTEMS AND METHODS FOR PERFORMING SIMULTANEOUS ABLATION 审中-公开
标题翻译：同时进行同步排除的系统和方法
公开(公告)号：US20090240247A1
公开(公告)日：2009-09-24
申请号：US12476871
申请日：2009-06-02
申请人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert F. Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/18 , A61B18/14
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.
摘要翻译：用于治疗组织的系统包括第一和第二消融装置，每个消融装置包括多个线电极并且并联耦合到发生器。在一个实施例中，发生器包括彼此并联耦合的第一和第二端子，并且第一和第二消融装置分别连接到第一和第二端子。或者，第一和第二消融装置使用“Y”电缆耦合到发生器的单个端子。接地电极与第一和第二消融装置相对的发生器耦合，用于单极操作。第一和第二电极阵列插入在组织区域内彼此相邻的第一和第二位置。能量同时传送到第一和第二阵列以在第一和第二部位产生损伤，优选地使得第一和第二病变重叠。

10. 发明授权

US07993335B2 Ablation probe for delivering fluid through porous structure 有权
标题翻译：用于通过多孔结构输送流体的消融探针
公开(公告)号：US07993335B2
公开(公告)日：2011-08-09
申请号：US11550374
申请日：2006-10-17
申请人： Robert F. Rioux , Robert Garabedian
发明人： Robert F. Rioux , Robert Garabedian
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/00065 , A61B2018/143 , A61B2018/1432 , A61B2218/002 , C04B38/0067 , C04B2111/00836 , C04B2111/94 , C04B35/00 , C04B38/0054
摘要： Ablation probes are provided for perfusing the tissue, while the tissue is ablated. The ablation probe comprises an elongated shaft and an ablative element, such as a needle electrode. The ablation probe further comprises a lumen that extends through the probe shaft, which will be used to deliver an fluid to the distal end of the probe shaft for perfusion into the surrounding tissue. The ablation probe further comprises a porous structure that is associated with the distal end of the shaft in fluid communication with the lumen. For example, the distal end of the shaft, or the entirety of the shaft, can be composed of the porous structure. Or, if the ablative element is an electrode, the electrode can be composed of the porous structure. Because the pores within the porous structure are pervasive, the fluid will freely flow out into the tissue notwithstanding that some of the pores may become clogged.
摘要翻译：提供消融探针用于灌注组织，同时组织被消融。消融探针包括细长轴和消融元件，例如针电极。消融探针还包括延伸穿过探针轴的内腔，其将用于将流体输送到探针轴的远端以灌注到周围组织中。消融探针还包括与轴的远端相关联的多孔结构，其与内腔流体连通。例如，轴的远端或轴的整体可以由多孔结构构成。或者，如果烧蚀元件是电极，则电极可以由多孔结构构成。因为多孔结构内的孔是普遍的，所以即使一些孔隙可能被堵塞，流体也可以自由流出到组织中。

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