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1. 发明授权

US06263230B1 System and method to determine the location and orientation of an indwelling medical device 有权
标题翻译：确定留置医疗器械的位置和方向的系统和方法
公开(公告)号：US06263230B1
公开(公告)日：2001-07-17
申请号：US09188049
申请日：1998-11-06
申请人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden , Gary B. Sanders
发明人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden , Gary B. Sanders
IPC分类号： A61B505
CPC分类号： G01V3/08 , A61B5/062 , A61B34/20 , A61B34/25 , A61B2034/2051 , A61B2090/376 , A61B2090/3958
摘要： A device to detect the location of a plurality of magnets uses a plurality of magnetic sensors, having sensor elements arranged in a known fashion. Each sensor element senses the magnetic field strength generated by each of the plurality of magnets and provides data indicative of the direction of the magnets in a three-dimensional space. The device uses fundamental equations for electricity and magnetism that relate the measured magnetic field strength to the location and strength of the magnetic dipole for each of the plurality of magnets. The device may use an iterative process to determine the actual location and orientation of each magnet. An initial estimation of the location and orientation of each magnet results in the generation of predicted magnetic field values. The predicted magnetic field values are compared with the actual measured values provided by the magnetic sensors. Based on a difference between the predicted values and the measured values, the device estimates a new location for each of the magnets and calculates new predicted magnetic field strength values. The iteration process continues until the predicted values match the measured values within a desired degree of tolerance. At this point, the estimated location and orientation of each of the magnets matches the actual location within a predetermined degree of tolerance.
摘要翻译：用于检测多个磁体的位置的装置使用具有已知方式布置的传感器元件的多个磁性传感器。每个传感器元件感测由多个磁体中的每一个产生的磁场强度，并提供指示磁体在三维空间中的方向的数据。该装置使用将测量的磁场强度与多个磁体中的每一个的磁偶极子的位置和强度相关联的电和磁性的基本方程。该装置可以使用迭代过程来确定每个磁体的实际位置和取向。每个磁体的位置和取向的初步估计导致预测的磁场值的产生。将预测的磁场值与由磁传感器提供的实际测量值进行比较。基于预测值和测量值之间的差异，设备估计每个磁体的新位置并计算新的预测磁场强度值。迭代过程一直持续到预期值与期望的公差范围内的测量值相匹配。在这一点上，每个磁体的估计位置和取向与预定公差范围内的实际位置相匹配。

2. 发明授权

US5879297A System and method to determine the location and orientation of an indwelling medical device 失效
公开(公告)号：US5879297A
公开(公告)日：1999-03-09
申请号：US852940
申请日：1997-05-08
申请人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
发明人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
IPC分类号： A61B5/06 , A61B19/00 , A61B5/00
CPC分类号： A61B5/06 , A61B34/20 , A61B2034/2051 , A61B2090/3958 , A61B34/25
摘要： A device to detect the location of a magnet coupled to an indwelling medical device within a patient uses three or more sets of magnetic sensors each having sensor elements arranged in a known fashion. Each sensor element senses the magnetic field strength generated by the magnet and provides data indicative of the direction of the magnet in a three-dimensional space. The device uses fundamental equations for electricity and magnetism that relate measured magnetic field strength and magnetic field gradient to the location and strength of a magnetic dipole. The device uses an iterative process to determine the actual location and orientation of the magnet. An initial estimate of the location and orientation of the magnet results in the generation of predicted magnetic field values. The predicted magnetic field values are compared with the actual measured values provided by the magnetic sensors. Based on the difference between the predicted values and the measured values, the device estimates a new location of the magnet and calculates new predicted magnetic field strength values. This iteration process continues until the predicted values match the measured values within a desired degree of tolerance. At that point, the estimated location matches the actual location within a predetermined degree of tolerance. A two-dimensional display provides an indication of the location of the magnet with respect to the housing of the detector. A depth indicator portion of the display can be used to provide a relative or absolute indication of the depth of the magnet within the patient.

3. 发明授权

US06292680B1 Non-invasive sensing of a physical parameter 有权
标题翻译：物理参数的无创感知
公开(公告)号：US06292680B1
公开(公告)日：2001-09-18
申请号：US09424160
申请日：2000-02-16
申请人： Christopher P. Somogyi , Robert N. Golden
发明人： Christopher P. Somogyi , Robert N. Golden
IPC分类号： A61B505
CPC分类号： A61B5/1126 , A61B5/0265 , A61B5/06 , A61B5/1121 , A61B5/224
摘要： There is disclosed a method and device for non-invasively sensing a physical parameter within the body of a patient by employing a magnetically-based sensing device and monitoring device. The magnetically-based sensing device has a first magnet and a second magnet which generate a combined magnet field. The first and second magnets are positioned such that a change in a physical parameter causes a change in the combined magnet field, which change is monitored by the monitoring device.
摘要翻译：公开了一种通过采用基于磁性的感测装置和监视装置非侵入性地感测患者身体内的物理参数的方法和装置。基于磁性的感测装置具有产生组合的磁场的第一磁体和第二磁体。第一和第二磁体被定位成使得物理参数的变化引起组合磁场的变化，该变化由监视装置监视。

4. 发明授权

US06216028B1 Method to determine the location and orientation of an indwelling medical device 有权
标题翻译：确定留置医疗设备的位置和方向的方法
公开(公告)号：US06216028B1
公开(公告)日：2001-04-10
申请号：US09169194
申请日：1998-10-08
申请人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
发明人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
IPC分类号： A61B505
CPC分类号： A61B5/06 , A61B5/062 , A61B34/20 , A61B34/25 , A61B2034/2051 , A61B2090/3958
摘要： A device to detect the location of a magnet coupled to an indwelling medical device within a patient uses three or more sets of magnetic sensors each having sensor elements arranged in a known fashion. Each sensor element senses the magnetic field strength generated by the magnet and provides data indicative of the direction of the magnet in a three-dimensional space. The device uses findamental equations for electricity and magnetism that relate measured magnetic field strength and magnetic field gradient to the location and strength of a magnetic dipole. The device uses an iterative process to determine the actual location and orientation of the magnet. An initial estimate of the location and orientation of the magnet results in the generation of predicted magnetic field values. The predicted magnetic field values are compared with the actual measured values provided by the magnetic sensors. Based on the difference between the predicted values and the measured values, the device estimates a new location of the magnet and calculates new predicted magnetic field strength values. This iteration process continues until the predicted values match the measured values within a desired degree of tolerance. At that point, the estimated location matches the actual location within a predetermined degree of tolerance. A two-dimensional display provides an indication of the location of the magnet with respect to the housing of the detector. A depth indicator portion of the display can be used to provide a relative or absolute indication of the depth of the magnet within the patient.
摘要翻译：用于检测耦合到患者内的留置医疗装置的磁体的位置的装置使用三组或更多组磁传感器，每组具有以已知方式布置的传感器元件。每个传感器元件感测由磁体产生的磁场强度，并提供指示磁体在三维空间中的方向的数据。该装置使用关于测量的磁场强度和磁场梯度与磁偶极子的位置和强度相关的电和磁性的关键方程。该设备使用迭代过程来确定磁体的实际位置和方向。磁体的位置和取向的初始估计导致预测的磁场值的产生。将预测的磁场值与由磁传感器提供的实际测量值进行比较。基于预测值和测量值之间的差异，设备估计磁体的新位置并计算新的预测磁场强度值。该迭代过程一直持续到预期值与期望的公差范围内的测量值相匹配。此时，估计位置与预定公差范围内的实际位置相匹配。二维显示器提供磁体相对于检测器壳体的位置的指示。显示器的深度指示器部分可用于提供患者内磁体深度的相对或绝对指示。

5. 发明授权

US06173715B1 Magnetic anatomical marker and method of use 有权
标题翻译：磁解剖标记及使用方法
公开(公告)号：US06173715B1
公开(公告)日：2001-01-16
申请号：US09259222
申请日：1999-03-01
申请人： Mika N. Sinanan , Christopher P. Somogyi , Robert N. Golden , Fred E. Silverstein , Andrei J. Gonzales
发明人： Mika N. Sinanan , Christopher P. Somogyi , Robert N. Golden , Fred E. Silverstein , Andrei J. Gonzales
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B2017/00004 , A61B2090/3937 , A61B2090/3954 , A61B2090/3987
摘要： An anatomical marker uses a permanent magnet to indicate a selected location within a patient. The magnet is enclosed within a non-degradable envelope and is coupled to a retention member that is preferably manufactured from a biodegradable material, such as a polyglucuronic acid based material. The retention member may include one or more barbs to retain the anatomical marker in the selected location. An insertion tool, usable with an endoscope, can insert the anatomical marker. A retention magnet is fixedly attached to the insertion tool and holds the anatomical marker in place due to the attractive magnetic forces between the retention magnet and the marker magnet in the non-biodegradable envelope. When the anatomical marker is securely fastened at the selected location in the patient, the forces exerted by the patient's body on the retention member exceed the attractive magnetic forces between the retention magnet and the magnet in the envelope, thus causing the anatomical marker to be released from the insertion tool. The location of the magnet may be subsequently detected using a magnetic detector system.
摘要翻译：解剖标记使用永磁体来指示患者内的选定位置。磁体被封闭在不可降解的外壳内，并且联接到优选由生物可降解材料制成的保持构件，例如聚葡糖醛酸基材料。保持构件可以包括一个或多个倒钩以将解剖标记保持在所选择的位置。可用于内窥镜的插入工具可以插入解剖标记。保持磁体固定地附接到插入工具，并且由于在不可生物降解的外壳中的保持磁体和标记磁体之间的有吸引力的磁力将解剖标记保持在适当位置。当解剖标记被牢固地固定在患者的所选位置时，患者身体施加在保持构件上的力超过保持磁体和外壳中的磁体之间的有吸引力的磁力，从而导致解剖标志物被释放从插入工具。随后可以使用磁检测器系统检测磁体的位置。

6. 发明授权

US6129668A System and method to determine the location and orientation of an indwelling medical device 失效
标题翻译：确定留置医疗器械的位置和方向的系统和方法
公开(公告)号：US6129668A
公开(公告)日：2000-10-10
申请号：US75280
申请日：1998-05-08
申请人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
发明人： David R. Haynor , Christopher P. Somogyi , Robert N. Golden
IPC分类号： A61B5/06 , A61B19/00 , A61B5/05
CPC分类号： A61B5/06 , A61B34/20 , A61B2017/00876 , A61B2034/2051 , A61B2090/376 , A61B2090/3958 , A61B34/25
摘要： A device to detect the location of a magnet coupled to an indwelling medical device within a patient uses three or more sets of magnetic sensors each having sensor elements arranged in a known fashion. Each sensor element senses the magnetic field strength generated by the magnet and provides data indicative of the direction of the magnet in a three-dimensional space. The device uses fundamental equations for electricity and magnetism that relate measured magnetic field strength and magnetic field gradient to the location and strength of a magnetic dipole. The device uses an iterative process to determine the actual location and orientation of the magnet. An initial estimate of the location and orientation of the magnet results in the generation of predicted magnetic field values. The predicted magnetic field values are compared with the actual measured values provided by the magnetic sensors. Based on the difference between the predicted values and the measured values, the device estimates a new location of the magnet and calculates new predicted magnetic field strength values. This iteration process continues until the predicted values match the measured values within a desired degree of tolerance. At that point, the estimated location matches the actual location within a predetermined degree of tolerance. A two-dimensional display provides an indication of the location of the magnet with respect to the housing of the detector. A depth indicator portion of the display can be used to provide a relative or absolute indication of the depth of the magnet within the patient.
摘要翻译：用于检测耦合到患者内的留置医疗装置的磁体的位置的装置使用三组或更多组磁传感器，每组具有以已知方式布置的传感器元件。每个传感器元件感测由磁体产生的磁场强度，并提供指示磁体在三维空间中的方向的数据。该设备使用电磁和磁力的基本方程，将测量的磁场强度和磁场梯度与磁偶极子的位置和强度相关联。该设备使用迭代过程来确定磁体的实际位置和方向。磁体的位置和取向的初始估计导致预测的磁场值的产生。将预测的磁场值与由磁传感器提供的实际测量值进行比较。基于预测值和测量值之间的差异，设备估计磁体的新位置并计算新的预测磁场强度值。该迭代过程一直持续到预期值与期望的公差范围内的测量值相匹配。此时，估计位置与预定公差范围内的实际位置相匹配。二维显示器提供磁体相对于检测器壳体的位置的指示。显示器的深度指示器部分可用于提供患者内磁体深度的相对或绝对指示。

7. 发明授权

US5775322A Tracheal tube and methods related thereto 失效
标题翻译：气管及其相关方法
公开(公告)号：US5775322A
公开(公告)日：1998-07-07
申请号：US669763
申请日：1996-06-27
申请人： Fred E. Silverstein , Robert N. Golden , Christopher P. Somogyi
发明人： Fred E. Silverstein , Robert N. Golden , Christopher P. Somogyi
IPC分类号： A61M16/04 , A61M16/00
CPC分类号： A61M16/0488 , A61M16/0411
摘要： There is disclosed a tracheal tube for insertion into the trachea of a patient. The tracheal tube includes a tube portion having a distal end, and a signal source associated with the tube portion at a predefined distance from its distal end. The tracheal tube is inserted into the trachea such that the signal source is immediately posterior to the patient's cricothyroid ligament. Methods related to confirming proper placement of the tracheal tube by detecting the signal source immediately posterior to the patient's cricothyroid ligament are also disclosed.
摘要翻译：公开了一种用于插入患者气管的气管插管。气管管包括具有远端的管部分和与其远端距预定距离的与管部分相关联的信号源。将气管插入气管中，使得信号源紧靠患者甲状腺韧带的后方。还公开了通过检测患者甲状腺韧带后方的信号源来确认气管插管的正确放置的方法。

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