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1. 发明授权

US4738958A Ansamycin antibiotic and its use as a medicament 失效
标题翻译：霉素抗生素及其用作药物
公开(公告)号：US4738958A
公开(公告)日：1988-04-19
申请号：US846945
申请日：1986-04-01
申请人： Christopher M. M. Franco , Goukanapalli C. S. Reddy , Triptikumar Mukhopadhyay , Bimal N. Ganguli , Hans-Wolfram Fehlhaber
发明人： Christopher M. M. Franco , Goukanapalli C. S. Reddy , Triptikumar Mukhopadhyay , Bimal N. Ganguli , Hans-Wolfram Fehlhaber
IPC分类号： A61K31/70 , A61P31/04 , C07D225/08 , C12P17/10 , C12R1/465 , C07D227/087 , A61K31/395
CPC分类号： C12P17/10 , C07D225/08 , Y10S435/886
摘要： The present invention relates to the compound naphthomycin H of the formula I ##STR1## and to a microbiological process for its preparation. The compound is active against Gram-positive bacteria and fungi and can be used as an antibiotic.
摘要翻译：本发明涉及式I＆lt; IMAGE＆gt;的化合物萘并霉素H及其制备的微生物学方法。该化合物对革兰氏阳性菌和真菌具有活性，可用作抗生素。

2. 发明授权

US5112858A Antibiotic, aranorosin, a microbiological process for the preparation thereof, and the use thereof as a pharmaceutical 失效
标题翻译：抗生素，阿那曲宁，其制备的微生物过程及其作为药物的用途
公开(公告)号：US5112858A
公开(公告)日：1992-05-12
申请号：US350288
申请日：1989-05-11
申请人： Kirity Roy , Triptikumar Mukhopadhyay , Goukanapalli C. S. Reddy , Erra K. S. Vijayakumar , Bimal N. Ganguli , Richard H. Rupp , Hans-Wolfram Fehlhaber , Herbert Kogler
发明人： Kirity Roy , Triptikumar Mukhopadhyay , Goukanapalli C. S. Reddy , Erra K. S. Vijayakumar , Bimal N. Ganguli , Richard H. Rupp , Hans-Wolfram Fehlhaber , Herbert Kogler
IPC分类号： A61K31/34 , A61P31/04 , A61P35/00 , C07D493/20 , C12N1/14 , C12P17/18 , C12R1/645
CPC分类号： C07D493/20 , C12P17/181 , C12R1/01
摘要： A new antibiotic, aranorosin, a microbiological process for the preparation thereof, and the use thereof as a pharmaceutical.Aranorosin, a compound of the formula ##STR1## can be prepared with the aid of the fungus culture Y-30499 (DSM 4151). Aranorosin has an antibiotic action as well as an action against malignant tumors.
摘要翻译：一种新的抗生素，aranorosin，其制备的微生物过程及其作为药物的用途。可以借助于真菌培养物Y-30499（DSM 4151）来制备阿曲诺星，式的化合物。 Aranorosin具有抗生素作用以及抗恶性肿瘤的作用。

3. 发明授权

US5387670A Antibiotic, deoxymulundocandin, a process for its production and its use as medicament 失效
标题翻译：抗生素，脱氧肉毒多卡因，其生产过程及其用作药物
公开(公告)号：US5387670A
公开(公告)日：1995-02-07
申请号：US645410
申请日：1991-01-24
申请人： Kirity Roy , Triptikumar Mukhopadhyay , Hans-Wolfram Fehlhaber , Herbert Kogler , Bimal N. Ganguli
发明人： Kirity Roy , Triptikumar Mukhopadhyay , Hans-Wolfram Fehlhaber , Herbert Kogler , Bimal N. Ganguli
IPC分类号： A61K38/00 , A61P31/04 , A61P31/10 , A61P37/00 , C07K7/06 , C07K7/56 , C12P17/18 , C12P21/02 , C12R1/66 , A61K37/02 , C07K5/12
CPC分类号： C07K7/56 , A61K38/00
摘要： Deoxymulundocandin, a compound of the formula I (SEQ. ID NO: 1) ##STR1## has an antiyeast, an antifungal and an immunomodulatory action.
摘要翻译：脱氧木兰多糖，式I化合物（SEQ ID NO：1）具有抗菌，抗真菌和免疫调节作用。

4. 发明授权

US5001258A Antibiotic, fumifungin, a microbial process for the preparation thereof, and the use thereof as a pharmaceutical 失效
标题翻译：抗生素，熏蒸素，其制备的微生物方法及其作为药物的用途
公开(公告)号：US5001258A
公开(公告)日：1991-03-19
申请号：US210373
申请日：1988-06-23
申请人： Triptikumar Mukhopadhyay , Kirity Roy , Hans-Wolfram Fehlhaber , Richard H. Rupp , Bimal N. Ganguli
发明人： Triptikumar Mukhopadhyay , Kirity Roy , Hans-Wolfram Fehlhaber , Richard H. Rupp , Bimal N. Ganguli
IPC分类号： C12P13/00 , A61K31/22 , A61P31/04 , C07C67/00 , C07C227/00 , C07C227/28 , C07C229/22 , C07C229/30 , C12N1/14 , C12P13/04 , C12R1/66
CPC分类号： C12P13/04
摘要： Fumifungin, a compound of the formula ##STR1## can be isolated from the culture broth of fungus culture No. Y-83,0405 (DSM 4152), and has bactericidal and fungicidal properties.
摘要翻译：可以从真菌培养物编号Y-83,0405（DSM 4152）的培养液中分离出具有式的化合物的Fumifungin，具有杀菌和杀真菌性质。

5. 发明授权

US5240959A Aranorosinol-A and aranorosinol-B produced by Pseudoarachniotus roseus 失效
标题翻译：由木犀草素生产的芳OL醇A和芳OL醇B
公开(公告)号：US5240959A
公开(公告)日：1993-08-31
申请号：US853040
申请日：1992-03-18
申请人： Kirity Roy , Erra K. S. Vijayakumar , Ravi G. Bhat , Triptikumar Mukhopadhyay , Bimal N. Ganguli
发明人： Kirity Roy , Erra K. S. Vijayakumar , Ravi G. Bhat , Triptikumar Mukhopadhyay , Bimal N. Ganguli
IPC分类号： A61K31/34 , A61P31/04 , C07D493/20 , C12P17/04 , C12P17/18 , C12R1/645
CPC分类号： C07D493/20 , C12P17/181 , Y10S435/822
摘要： Aranorosinol-A and Aranorosinol-B are compounds of the formula ##STR1## in which R is H (Aranorosinol-A) or CH.sub.2 COCH.sub.3 (Aranorosinol-B); said compounds have antibacterial and antifungal activity.

6. 发明授权

US06809177B1 Process for the conversion of echinocandin class of peptides to their c4-homotyrosine monodeoxy analogues 失效
标题翻译：将棘白菌素类肽转化为其c4-同型酪氨酸单体氧化物类似物的方法
公开(公告)号：US06809177B1
公开(公告)日：2004-10-26
申请号：US09673836
申请日：2001-03-29
申请人： Triptikumar Mukhopadhyay , Kenia Jayvanti , Erra Koteswara Satya Vijaya Kumar
发明人： Triptikumar Mukhopadhyay , Kenia Jayvanti , Erra Koteswara Satya Vijaya Kumar
IPC分类号： A61K3812
CPC分类号： C07K7/56 , Y10S930/19 , Y10S930/27
摘要： The invention relates to a process for the conversion of echinocandin class of peptides to their C4-homotyrosine monodeoxy analogues, particularly mulundocandin to deoxymulundocandin, which consists of a single step selective reduction of C4-htyr (homotyrosine) hydroxyl group of echinocandins to their monodeoxy analogues under neutral conditions without prior protection/deprotection of the equally facile C5-Orn (ornithine) hydroxyl group and purification of the monodeoxy compound from the crude reaction mixture.
摘要翻译：本发明涉及将棘白菌素类的肽转化为其C4-同型酪氨酸单脱氧类似物，特别是将mulundocandin转化为脱氧木兰多糖，其由棘白菌素的C4-htyr（均一酪氨酸）羟基选择性还原为其单脱氧类似物在没有预先保护/脱保护同样容易的C5-Orn（鸟氨酸）羟基）和从粗反应混合物中纯化单脱氧化合物的中性条件下进行。

7. 发明授权

US07914824B2 Herbal extract for renal disorders 有权
标题翻译：草药提取物用于肾脏疾病
公开(公告)号：US07914824B2
公开(公告)日：2011-03-29
申请号：US10591023
申请日：2005-04-04
申请人： Vidya Narayan Acharya , Triptikumar Mukhopadhyay , Swati Ajay Piramal
发明人： Vidya Narayan Acharya , Triptikumar Mukhopadhyay , Swati Ajay Piramal
IPC分类号： A01N65/00
CPC分类号： A61K36/59 , Y02A50/473 , A61K2300/00
摘要： The present invention relates to the use of standardized extract of Tinospora cordifolia as an immunoadjuvant in the treatment of renal disorders such as nephrotic syndrome and chronic recurrent urinary tract infections, both complicated and uncomplicated.The present invention also relates to pharmaceutical compositions comprising the standardized extract of Tinospora cordifolia. The present invention further relates to a method of treatment of renal disorders such as recurrent urinary tract infection particularly occurring due to relapsing E. coli, Klebsiella and other gram negative infections and to a method of treatment of nephrotic syndrome using standardized extract of Tinospora cordifolia as an immunoadjuvant in conjunction with conventional therapy.
摘要翻译：本发明涉及Tinospora cordifolia的标准提取物作为免疫佐剂用于治疗肾脏疾病如肾病综合征和慢性复发性尿路感染的复杂和不复杂的用途。本发明还涉及包含Tinospora cordifolia的标准化提取物的药物组合物。本发明还涉及一种治疗肾脏疾病的方法，例如由于复发性大肠杆菌，克雷伯氏菌和其他革兰氏阴性感染而特别发生的复发性尿路感染，以及使用Tinospora cordifolia的标准化提取物治疗肾病综合征的方法结合常规治疗的免疫佐剂。

8. 发明申请

US20080274212A1 Herbal Extract for Renal Disorders 有权
标题翻译：草药提取物用于肾脏疾病
公开(公告)号：US20080274212A1
公开(公告)日：2008-11-06
申请号：US10591023
申请日：2005-04-04
申请人： Vidya Narayan Acharya , Triptikumar Mukhopadhyay , Swati Ajay Piramal
发明人： Vidya Narayan Acharya , Triptikumar Mukhopadhyay , Swati Ajay Piramal
IPC分类号： A61K36/18 , A61P13/12 , A61P31/04
CPC分类号： A61K36/59 , Y02A50/473 , A61K2300/00
摘要： The present invention relates to the use of standardized extract of Tinospora cordifolia as an immunoadjuvant in the treatment of renal disorders such as nephrotic syndrome and chronic recurrent urinary tract infections, both complicated and uncomplicated.The present invention also relates to pharmaceutical compositions comprising the standardized extract of Tinospora cordifolia. The present invention further relates to a method of treatment of renal disorders such as recurrent urinary tract infection particularly occurring due to relapsing E. coli, Klebsiella and other gram negative infections and to a method of treatment of nephrotic syndrome using standardized extract of Tinospora cordifolia as an immunoadjuvant in conjunction with conventional therapy.
摘要翻译：本发明涉及Tinospora cordifolia的标准提取物作为免疫佐剂用于治疗肾脏疾病如肾病综合征和慢性复发性尿路感染的复杂和不复杂的用途。本发明还涉及包含Tinospora cordifolia的标准化提取物的药物组合物。本发明还涉及一种治疗肾脏疾病的方法，例如由于复发性大肠杆菌，克雷伯氏菌和其他革兰氏阴性感染而特别发生的复发性尿路感染，以及使用Tinospora cordifolia的标准化提取物治疗肾病综合征的方法结合常规治疗的免疫佐剂。

9. 发明申请

US20110135772A1 SKIN CARE AGENT AND COMPOSITIONS THEREOF 审中-公开
标题翻译：护肤品及其组合物
公开(公告)号：US20110135772A1
公开(公告)日：2011-06-09
申请号：US13054839
申请日：2009-03-16
申请人： Gottumukkala Venkateswara Rao , Triptikumar Mukhopadhyay , Guruswamy Damodaran Rajesh
发明人： Gottumukkala Venkateswara Rao , Triptikumar Mukhopadhyay , Guruswamy Damodaran Rajesh
IPC分类号： A61K8/60 , A61K8/97 , A61Q19/00 , A61Q19/08
CPC分类号： A61K8/60 , A61K8/37 , A61K8/97 , A61K2800/592 , A61Q19/08
摘要： A skin care agent and cosmetic and/or dermopharmaceutical compositions involving selectively polygallate molecule either singly or as a synergistic mixture of a polygallate molecule and a gallic acid ester in an effective amount along with an acceptable vehicle with or without other skin benefit agents. Preferably, the active mixture or ingredients is selectively obtained by appropriate combination of suitable sources including plants rich in individual ingredients or a single source such as the skin and/or kernel of Mangifera indica Linn.
摘要翻译：皮肤护理剂和化妆品和/或皮肤药物组合物以及具有或不具有其它皮肤有益剂的可接受的媒介物，其有效量选择性地选择性聚对苯二甲酸乙二醇酯分子单独或作为多糖酸酯分子和没食子酸酯的协同混合物。优选地，活性混合物或成分通过合适的来源（包括富含单一成分的植物的植物）或单一来源（例如芒of的皮肤和/或核）的适当组合来选择性地获得。

10. 发明授权

US06812223B2 Crystalline glucosamine sulfate metal salts and processes for preparing the same 失效
标题翻译：结晶葡糖胺硫酸盐金属盐及其制备方法
公开(公告)号：US06812223B2
公开(公告)日：2004-11-02
申请号：US10433317
申请日：2003-06-02
申请人： Triptikumar Mukhopadhyay , Ravi Gajanan Bhat , E. S. Sreekumar
发明人： Triptikumar Mukhopadhyay , Ravi Gajanan Bhat , E. S. Sreekumar
IPC分类号： A61K3170
CPC分类号： C07H5/06
摘要： The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic disorders of the osteo-articular tissues. More particularly, the present invention relates to novel crystalline glucosamine sulphate metal salts having low metal content wherein the metal may be either sodium or potassium. The present invention further relates to a solution-based and a solvent-free process for the preparation of the novel crystalline glucosamine sulphate metal salts having low metal content and to pharmaceutical compositions comprising the novel crystalline glucosamine sulphate metal salts having low metal content.
摘要翻译：本发明涉及用于治疗急性和慢性形式的风湿性关节炎疾病的新型结晶葡糖胺硫酸盐金属盐和源于骨关节组织代谢紊乱的所有病理状态。更具体地，本发明涉及具有低金属含量的新的结晶葡糖胺硫酸盐金属盐，其中金属可以是钠或钾。本发明还涉及用于制备具有低金属含量的新型结晶葡糖胺硫酸盐金属盐的基于溶液和无溶剂的方法，以及包含具有低金属含量的新型结晶葡糖胺硫酸盐金属盐的药物组合物。

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