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    • 1. 发明授权
    • Flavonoid complexes
    • 黄酮类复合物
    • US07943662B2
    • 2011-05-17
    • US11791544
    • 2005-11-03
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • A61K31/353A61K31/724
    • A61K8/498A61K8/04A61K8/046A61K8/602A61K8/738A61K2800/56A61Q17/04A61Q19/00A61Q19/08C07D311/30
    • The invention relates to complexes of certain flavonoid derivatives, of the formula (I), where R1 and R2 are selected from H and OR11, where OR11 stands, independently of one another, for OH, straight-chain or branched C1- to C20-alkoxy groups, straight-chain or branched C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may in each case also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, with the proviso that at least one radical from R1 and R2 stands for OR11, and R3 to R10 may be identical or different and stand, independently of one another, for radicals which are substantially inert with respect to the UV properties, to compositions which comprise such complexes, to corresponding processes for the preparation of the complexes or the compositions comprising the latter, and to the use thereof, in particular for the care, preservation or improvement of the general condition of the skin or hair and for light protection.
    • 本发明涉及式(I)的某些类黄酮衍生物的复合物,其中R1和R2选自H和OR11,其中OR11彼此独立地表示OH,直链或支链C1- 烷氧基,直链或支链C 3 -C 20链烯氧基,直链或支链C 1至C 20 - 羟基烷氧基,其中羟基可以键合到链中的伯或仲碳原子上, 此外,烷基链还可被氧,和/或C 3 -C 10环烷氧基和/或C 3至C 12 - 环烯基氧基间隔,其中每种情况下的环也可以被 - (CH 2)n - 基团桥连 ,其中n = 1至3,和/或单糖基和/或寡糖基自由基,条件是R 1和R 2中至少一个基团代表OR 11,并且R 3至R 10可以相同或不同,独立地为一个 另一个,对于相对于UV性质基本上是惰性的基团,可以是组合物 涉及用于制备复合物或包含其的组合物的相应方法及其用途,特别是用于护理,保存或改善皮肤或毛发的一般状况以及用于轻度保护的方法。
    • 2. 发明申请
    • CHROMEN-4-ONE DERIVATIVES AS SELF-TANNING SUBSTANCE
    • CHROMEN-4-ONE衍生物作为自拍物质
    • US20090220438A1
    • 2009-09-03
    • US12162527
    • 2007-01-09
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • A61K8/49C07D311/04A61Q17/04
    • C07D311/22A61K8/498A61Q19/04
    • The invention relates to the use of compounds of the formula (I), where R1 and R2 may be identical or different and stand for H, OH, OCH3, CH3, CH2OH or CH2OCH3, R3 stands for H or straight-chain or branched C1- to C20-alkyl groups, R4 stands for H or OR8, R5 and R6 may be identical or different and are selected from —H, —OH, straight-chain or branched C1 to C20-alkyl groups, straight-chain or branched C3- to C20-alkenyl groups, straight-chain or branched C1- to C20-hydroxyalkyl groups, where the hydroxyl group may be bonded to a primary or secondary carbon atom of the chain, and furthermore the allyl chain may also be interrupted by oxygen, and R8 stands for H or straight-chain or branched C1- to C20-alkyl groups, with the proviso that R2 does not denote H if R1 denotes CH3, as self-tanning agents, and to compounds and the preparation thereof.
    • 本发明涉及式(I)化合物的用途,其中R1和R2可以相同或不同,代表H,OH,OCH3,CH3,CH2OH或CH2OCH3,R3代表H或直链或支链C1 - 至C20烷基,R4代表H或OR8,R5和R6可以相同或不同,选自-H,-OH,直链或支链C1至C20-烷基,直链或支链C3 - 至20个烯基,直链或支链的C 1 -C 20羟基烷基,其中羟基可以键合到链的伯或仲碳原子上,此外,烯丙基链也可以被氧中断, 并且R 8代表H或直链或支链C 1至C 20烷基,条件是如果R 1表示CH 3,R 2不表示H,作为自鞣剂,以及化合物及其制备。
    • 3. 发明申请
    • Flavonoid Complexes
    • 黄酮类复合物
    • US20080112905A1
    • 2008-05-15
    • US11791544
    • 2005-11-03
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • Christophe CarolaAnne ToullecHerwig Buchholz
    • A61K8/73A61Q17/04
    • A61K8/498A61K8/04A61K8/046A61K8/602A61K8/738A61K2800/56A61Q17/04A61Q19/00A61Q19/08C07D311/30
    • The invention relates to complexes of certain flavonoid derivatives, of the formula (1), where R1 and R2 are selected from H and OR11, where OR11 stands, independently of one another, for OH, straight-chain or branched C1- to C20-alkoxy groups, straight-chain or branched C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may in each case also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, with the proviso that at least one radical from R1 and R2 stands for OR11, and R3 to R10 may be identical or different and stand, independently of one another, for radicals which are substantially inert with respect to the UV properties, to compositions which comprise such complexes, to corresponding processes for the preparation of the complexes or the compositions comprising the latter, and to the use thereof, in particular for the care, preservation or improvement of the general condition of the skin or hair and for light protection.
    • 本发明涉及式(1)的某些类黄酮衍生物的复合物,其中R 1和R 2选自H和OR 11 >,其中OR 11彼此独立地表示OH,直链或支链C 1至C 20 - 烷氧基 直链或支链C 3 - 至C 20 - 炔基氧基,直链或支链C 1至C 1 - 20个羟基烷氧基,其中羟基可以键合到链中的伯或仲碳原子上,此外烷基链也可以被氧中断,和/或C 3 < C 12 - 环烷氧基和/或C 3 - 至C 12 - 环烯氧基,其中环可以在每个 情况也可以通过其中n = 1-3的基团和/或单糖基和/或寡糖基自由基桥连,条件是 R 1和R 2中的至少一个基团代表OR SUP> 11和R 3至R 10可以相同或不同,彼此独立地表示相对于基本上为惰性的基团 UV性质,包含这种复合物的组合物,用于制备复合物或包含其的组合物的相应方法及其用途,特别是用于护理,保存或改善皮肤的一般状况或 头发和保护光。
    • 8. 发明授权
    • Light-protection agents
    • 防光剂
    • US07128900B2
    • 2006-10-31
    • US10622123
    • 2003-07-18
    • Herwig BuchholzChristophe CarolaSophie Perruchon
    • Herwig BuchholzChristophe CarolaSophie Perruchon
    • A61Q17/00A61Q17/04A61Q19/00
    • A61K31/352A23L33/10A61K8/37A61K8/498A61K8/602A61K31/7048A61K2800/52A61Q17/04A61Q19/00A61Q19/08C07D311/30C07H15/04C07H17/07
    • The invention relates to a preparation having light-protection properties comprising at least one compound of the formula I where R1 and R2 are selected from H and OR11, where each OR11, independently of the others, is OH, a straight-chain or branched C1- to C20-alkoxy group, a straight-chain or branched C3- to C20-alkenyloxy group, a straight-chain or branched C1- to C20-hydroxyalkoxy group, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or a C3- to C10-cycloalkoxy group and/or C3- to C12-cyclo-alkenyloxy group, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, and/or a mono- and/or oligoglycosyl radical, with the proviso that at least one radical from R1 and R2 is OR11, and R3 is a radical OR11, and R4 to R7 and R10 may be identical or different and are, independently of one another, radicals which are substantially inert with respect to the UV properties.
    • 本发明涉及一种具有光保护性质的制剂,其包含至少一种式I的化合物,其中R 1和R 2选自H和OR 11 其中每个OR 11与其它独立地是OH,直链或支链C 1至C 20 直链或支链C 1 -C 20烷基,直链或支链C 1 -C 20 - 烷氧基,直链或支链C 3〜C 20 - 炔基氧基,直链或支链C 1〜 - C 20 - 羟基烷氧基,其中羟基可以键合到链中的伯或仲碳原子上,此外烷基链也可以被氧中断,和/或 C 3〜C 10 - 环烷氧基和/或C 3〜C 12 - 环 - 链烯氧基,其中各环也可以通过其中n = 1至3的 - (CH 2 CH 2)n - 基团桥连,和/或单 - 和/ 或寡糖基,其条件是至少一个R 1和R 2的基团 R 2是OR 11,R 3是基团OR 11,R 4, R 0〜R 7和R 10可以相同或不同,彼此独立地为相对于UV性质基本上为惰性的基团。