专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070155738A1 Heterobicyclic metalloprotease inhibitors 审中-公开
标题翻译：异双环金属蛋白酶抑制剂
公开(公告)号：US20070155738A1
公开(公告)日：2007-07-05
申请号：US11602140
申请日：2006-11-20
申请人： Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochguertel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
发明人： Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochguertel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Biesinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
IPC分类号： A61K31/538 , A61K31/5377 , A61K31/519 , C07D491/04 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
摘要翻译：本发明一般涉及含酰胺基的药剂，特别涉及含酰胺的杂双环金属蛋白酶抑制剂化合物。更具体地，本发明提供了一类新型的杂双环MMP-13抑制和MMP-3抑制化合物，其与当前已知的MMP-13和MMP-3抑制剂相比具有增强的效力。

2. 发明申请

US20080161300A1 Heterobicyclic metalloprotease inhibitors 审中-公开
标题翻译：异双环金属蛋白酶抑制剂
公开(公告)号：US20080161300A1
公开(公告)日：2008-07-03
申请号：US12001041
申请日：2007-12-07
申请人： Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochgurtel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Beisinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
发明人： Christoph Steeneck , Christian Gege , Frank Richter , Heiko Kroth , Matthias Hochgurtel , Michael Essers , Joshua Van Veldhuizen , Bert Nolte , Brian Gallagher , Tim Feuerstein , Matthias Schneider , Torsten Arndt , Hongbo Deng , Ralf Beisinger , Xinyuan Wu , Harald Bluhm , Irving Sucholeiki , Arthur Taveras
IPC分类号： A61K31/536 , A61K31/519 , C07D265/36 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting and MMP-3 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 and MMP-3 inhibitors.
摘要翻译：本发明一般涉及含酰胺基的药剂，特别涉及含酰胺的杂双环金属蛋白酶抑制剂化合物。更具体地，本发明提供了一类新型的杂双环MMP-13抑制和MMP-3抑制化合物，其与当前已知的MMP-13和MMP-3抑制剂相比具有增强的效力。

3. 发明申请

US20060293345A1 Heterobicyclic metalloprotease inhibitors 审中-公开
标题翻译：异双环金属蛋白酶抑制剂
公开(公告)号：US20060293345A1
公开(公告)日：2006-12-28
申请号：US11440087
申请日：2006-05-22
申请人： Christoph Steeneck , Christian Gege , Frank Richter , Matthias Hochguertel , Tim Feuerstein , Harald Bluhm , Irving Sucholeiki , Jurgen Boer , Xinyuan Wu , Matthias Schneider , Bert Nolte , Brian Gallagher , Joshua Van Veldhuizen , Hongbo Dong , Michael Essers , Heiko Kroth , Andrew Kiely , Timothy Powers , Arthur Taveras
发明人： Christoph Steeneck , Christian Gege , Frank Richter , Matthias Hochguertel , Tim Feuerstein , Harald Bluhm , Irving Sucholeiki , Jurgen Boer , Xinyuan Wu , Matthias Schneider , Bert Nolte , Brian Gallagher , Joshua Van Veldhuizen , Hongbo Dong , Michael Essers , Heiko Kroth , Andrew Kiely , Timothy Powers , Arthur Taveras
IPC分类号： A61K31/519 , C07D491/04 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP-13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP-13 inhibitors.
摘要翻译：本发明一般涉及含酰胺基的药剂，特别涉及含酰胺的杂双环金属蛋白酶抑制剂化合物。更具体地说，本发明提供了一类新型的杂双环MMP-13抑制化合物，其表现出与目前已知的MMP-13抑制剂有关的效力。

4. 发明申请

US20060173183A1 Multicyclic bis-amide MMP inhibitors 审中-公开
标题翻译：多元双酰胺MMP抑制剂
公开(公告)号：US20060173183A1
公开(公告)日：2006-08-03
申请号：US11324037
申请日：2005-12-30
申请人： Timothy Powers , Christoph Steeneck , Ralf Biesinger , Harald Bluhm , Hongbo Deng , Rory Dodd , Brian Gallagher , Christian Gege , Matthias Hochgurtel , Andrew Kiely , Frank Richter , Matthias Schneider , Irving Sucholeiki , Joshua Van Veldhuizen , Xinyuan Wu , Arthur Taveras
发明人： Timothy Powers , Christoph Steeneck , Ralf Biesinger , Harald Bluhm , Hongbo Deng , Rory Dodd , Brian Gallagher , Christian Gege , Matthias Hochgurtel , Andrew Kiely , Frank Richter , Matthias Schneider , Irving Sucholeiki , Joshua Van Veldhuizen , Xinyuan Wu , Arthur Taveras
IPC分类号： C07D417/02 , C07D403/02 , C07D413/02
CPC分类号： C07D239/28 , C07D239/30 , C07D239/42 , C07D239/70 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention relates generally to bis-amide group containing pharmaceutical agents, and in particular, to multicyclic bis-amide MMP-13 inhibitor compounds. More particularly, the present invention provides a new class of MMP-13 inhibiting compounds, containing a pyrimidinyl bis-amide group in combination with a heterocyclic moiety, that exhibit an increased potency and solubility in relation to currently known bis-amide group containing MMP-13 inhibitors.
摘要翻译：本发明一般涉及含有双酰胺基团的药物，特别涉及多元双酰胺MMP-13抑制剂化合物。更具体地，本发明提供了一类新的MMP-13抑制化合物，其包含与杂环部分组合的嘧啶基双酰胺基团，其相对于目前已知的含有MMP-1的双酰胺基团显示增加的效力和溶解度， 13抑制剂。

5. 发明申请

US20070155737A1 Heterobicyclic metalloprotease inhibitors 审中-公开
标题翻译：异双环金属蛋白酶抑制剂
公开(公告)号：US20070155737A1
公开(公告)日：2007-07-05
申请号：US11602116
申请日：2006-11-20
申请人： Brian Gallagher , Joshua Van Veldhuizen , Xinyuan Wu , Hongbo Deng , Irving Sucholeiki , Matthias Hochguertel , Harald Bluhm , Arthur Taveras
发明人： Brian Gallagher , Joshua Van Veldhuizen , Xinyuan Wu , Hongbo Deng , Irving Sucholeiki , Matthias Hochguertel , Harald Bluhm , Arthur Taveras
IPC分类号： A61K31/5377 , C07D491/04 , C07D487/04 , A61K31/538 , A61K31/519
CPC分类号： C07D487/04
摘要： The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic ADAMTS-4 inhibiting compounds.
摘要翻译：本发明一般涉及含酰胺基的药物，尤其涉及含酰胺的杂双环金属蛋白酶抑制剂化合物。更具体地说，本发明提供了一类新型的异双环ADAMTS-4抑制化合物。

6. 发明申请

US20080021024A1 Metalloprotease inhibitors 审中-公开
标题翻译：金属蛋白酶抑制剂
公开(公告)号：US20080021024A1
公开(公告)日：2008-01-24
申请号：US11824525
申请日：2007-06-29
申请人： Irving Sucholeiki , Christian Gege , Brian Gallagher , Timothy Powers , Hongbo Deng , Xinyuan Wu , Christoph Steeneck , Andrew Kiely , Arthur Taveras
发明人： Irving Sucholeiki , Christian Gege , Brian Gallagher , Timothy Powers , Hongbo Deng , Xinyuan Wu , Christoph Steeneck , Andrew Kiely , Arthur Taveras
IPC分类号： C07D239/24 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/536 , A61P17/00 , C12N9/99 , C07D265/36 , A61P19/00 , A61P25/00 , A61P3/00 , A61P9/00
CPC分类号： C07D403/12 , C07D239/38 , C07D239/42 , C07D401/12 , C07D401/14 , C07D403/10 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14
摘要： The present invention relates to amide containing aromatic MMP inhibiting compounds with a mono-amide heteroaromatic group, of formulas I and II:
摘要翻译：本发明涉及具有式I和II的单酰胺杂芳族基团的含酰胺芳香族MMP抑制化合物：

7. 发明授权

US08776611B2 Remotely accessible subsea strain sensor assemblies and methods 失效
标题翻译：可遥控海底应变传感器组件和方法
公开(公告)号：US08776611B2
公开(公告)日：2014-07-15
申请号：US13303031
申请日：2011-11-22
申请人： Jonathan Sangel , Andrew Mail , Brian Gallagher , John Engel
发明人： Jonathan Sangel , Andrew Mail , Brian Gallagher , John Engel
IPC分类号： G01N3/00
CPC分类号： E21B47/0006 , E21B17/01
摘要： A system and method for the installation and removal of monitoring equipment is disclosed. In some embodiments, the monitoring equipment may be installed or removed using a remotely operated vehicle. In certain implementations, the monitoring system includes a sensor assembly connectable to a tubular member, an alignment tool for installing or removing the sensor assembly to and from the tubular member, and an alignment cage for facilitating access of the alignment tool to the sensor assembly. In some embodiments, the alignment tool may be aligned with the sensor assembly for installation or removal as a result of the alignment tool being inserted through the alignment cage.
摘要翻译：公开了一种用于安装和拆卸监控设备的系统和方法。在一些实施例中，可以使用远程操作的车辆来安装或移除监视设备。在某些实施方案中，监测系统包括可连接到管状构件的传感器组件，用于将传感器组件安装或从管状构件移除的对准工具，以及用于便于对准工具接近传感器组件的对准保持架。在一些实施例中，对准工具可以与传感器组件对齐，用于通过对准工具插入对准框架中而进行安装或移除。

8. 发明申请

US20120317186A1 WEB BASED SYSTEM AND METHOD FOR CROSS-SITE PERSONALISATION 审中-公开
标题翻译：基于WEB的系统和用于跨站点个性化的方法
公开(公告)号：US20120317186A1
公开(公告)日：2012-12-13
申请号：US13495260
申请日：2012-06-13
申请人： Kevin Koidl , Brian Gallagher , Owen Conlan , Vincent Wade
发明人： Kevin Koidl , Brian Gallagher , Owen Conlan , Vincent Wade
IPC分类号： G06F15/16
CPC分类号： H04L67/306 , G06F16/958 , H04L67/22 , H04L67/34
摘要： A system and a method for configuring distributed network content in real time are disclosed. The system comprises a network, a plurality of user terminals and at least fist and second servers, all being connected to the network. The first server stores network content and distributes it according to network requests of remote user terminals. Each user terminal communicates data representative of user interaction with at least a portion of the network content to the second server, at which it is stored. The second server processes the stored data into respective network content-configuring data for each user terminal and the first server distributes next network content to each user terminal according to the respective network content-configuring data received from the at least second server.
摘要翻译：公开了实时配置分布式网络内容的系统和方法。该系统包括网络，多个用户终端和至少第一和第二服务器，全部连接到网络。第一台服务器存储网络内容，并根据远程用户终端的网络请求进行分发。每个用户终端将表示与网络内容的至少一部分的用户交互的数据传送到存储在其上的第二服务器。第二服务器将存储的数据处理成用于每个用户终端的相应的网络内容配置数据，并且第一服务器根据从至少第二服务器接收的相应的网络内容配置数据向每个用户终端分发下一个网络内容。

9. 发明授权

US07736145B1 Candle wick straightening method and apparatus 失效
标题翻译：蜡烛矫正方法及装置
公开(公告)号：US07736145B1
公开(公告)日：2010-06-15
申请号：US10138022
申请日：2002-05-03
申请人： Daivid G. Horvath , Brian Gallagher
发明人： Daivid G. Horvath , Brian Gallagher
IPC分类号： F23D3/34
CPC分类号： F23D3/34
摘要： A method and apparatus for inserting wicks into candles formed in jars or containers characterized by a device comprised of a hollow tube, sealed on one end, in which a wick and wick base can snugly fit, and a crosspiece having width greater than width of the mouth of a jar so that after candle wax is poured, the wick straightening device is inserted into the jar and is removed after the wax has cooled so that the wick will remain straight even after the candle wax has cooled.
摘要翻译：一种用于将灯芯插入形成在罐或容器中的蜡烛中的方法和装置，其特征在于由一个中空管组成的装置，该中空管在其一端密封，其中芯和灯芯基座可以紧密配合，并且具有宽度大于将瓶口蜡浇注后，将芯线矫直装置插入瓶中，并在蜡冷却后取出，使蜡烛蜡冷却后保持直线。

10. 发明申请

US20100017311A1 ASSET RECOVERY SYSTEM AND METHOD 审中-公开
标题翻译：资产恢复系统和方法
公开(公告)号：US20100017311A1
公开(公告)日：2010-01-21
申请号：US12504384
申请日：2009-07-16
申请人： Brian Gallagher
发明人： Brian Gallagher
IPC分类号： G06Q10/00 , G06Q90/00 , G06F15/16
CPC分类号： G06Q10/00 , G06Q10/087 , G06Q40/12 , G06Q99/00
摘要： An asset recovery system and method is provided for recovering value from shipped products that are returned and/or rejected by the purchaser or recipient. The system and method include inspecting the rejected or returned product at a returns center, assessing the cost to repair or refurbish the product. If the assessment is within a predetermined cost structure the product is repaired or refurbished and placed in a saleable item inventory for resale to a customer. If the assessment is outside the predetermined cost structure, the product is liquidated.
摘要翻译：提供资产回收系统和方法，用于从出货产品中回收和/或拒绝买方或收货人的价值。该系统和方法包括在退货中心检查被拒绝或退回的产品，评估修理或翻新产品的成本。如果评估在预定的成本结构内，则产品进行维修或翻新，并将其放入可销售物品库存中以转售给客户。如果评估超出预定的成本结构，产品将被清算。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式