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1. 发明授权

US07729511B2 Method and device for safeguarding a hazardous area 有权
标题翻译：保护危险区域的方法和装置
公开(公告)号：US07729511B2
公开(公告)日：2010-06-01
申请号：US11088041
申请日：2005-03-23
申请人： Christian Wöhler , Werner Progscha , Lars Krüger , Dietmar Döttling , Martin Wendler
发明人： Christian Wöhler , Werner Progscha , Lars Krüger , Dietmar Döttling , Martin Wendler
IPC分类号： G06K9/00
CPC分类号： F16P3/142 , B25J9/1674 , B25J9/1697 , B25J19/06 , G06T7/001 , G06T2207/10012 , G06T2207/30108 , G06T2207/30196
摘要： In order to safeguard a hazardous area, in particular the hazardous area of an automatically operating machine, images of the hazardous area are recorded with at least a first and a second image recording unit that are arranged offset from one another. The images of the scene are subjected to three-dimensional scene analyses using different three-dimensional scene analysis methods, and the hazardous area is safeguarded when at least one of the scene analysis methods detects a foreign object.
摘要翻译：为了保护危险区域，特别是自动操作机器的危险区域，危险区域的图像被记录有至少第一和第二图像记录单元，该第一和第二图像记录单元被布置为彼此偏移。使用不同的三维场景分析方法对场景的图像进行三维场景分析，并且当至少一个场景分析方法检测到异物时，对危险区域进行保护。

2. 发明授权

US09586891B2 Estrogen receptor ligands 有权
标题翻译：雌激素受体配体
公开(公告)号：US09586891B2
公开(公告)日：2017-03-07
申请号：US14234916
申请日：2012-08-02
申请人： Aiping Cheng , Neeraj Garg , Lars Krüger , Joakim Löfstedt , Eva Koch , Konrad Koehler , Lars Hagberg , Daniel Nöteberg
发明人： Aiping Cheng , Neeraj Garg , Lars Krüger , Joakim Löfstedt , Eva Koch , Konrad Koehler , Lars Hagberg , Daniel Nöteberg
IPC分类号： C07C251/48 , A61K31/381 , C07D261/08 , C07D207/327 , C07D213/58 , C07D215/12 , C07D217/14 , C07D231/12 , C07D233/64 , C07D235/16 , C07D277/30 , C07D277/34 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/87 , C07D317/60 , C07D333/20 , C07D409/10 , C07D413/10 , C07C209/68 , A61K31/155 , A61K31/341 , A61K31/416 , A61K31/42 , A61K31/4418 , A61K31/47 , A61K31/472 , C07D215/14 , C07D217/16 , C07D333/24
CPC分类号： A61K31/472 , A61K31/155 , A61K31/165 , A61K31/277 , A61K31/341 , A61K31/343 , A61K31/365 , A61K31/381 , A61K31/402 , A61K31/404 , A61K31/415 , A61K31/416 , A61K31/4192 , A61K31/42 , A61K31/44 , A61K31/4418 , A61K31/47 , C07C209/68 , C07C251/48 , C07D207/327 , C07D213/58 , C07D215/12 , C07D215/14 , C07D217/14 , C07D217/16 , C07D231/12 , C07D233/64 , C07D235/16 , C07D261/08 , C07D277/30 , C07D277/34 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/87 , C07D317/60 , C07D333/20 , C07D333/24 , C07D409/10 , C07D413/10 , C07C211/65
摘要： Compounds of formula (I) or a pharmaceutically acceptable ester, amide, carbamate or salt thereof, including a salt of such an ester, amide or carbamate in which R1 to R9 have meanings as defined in the Specification, are useful as estrogen receptor ligands.
摘要翻译：式（I）化合物或其药学上可接受的酯，酰胺，氨基甲酸酯或其盐，包括其中R 1至R 9具有如本说明书中所定义的含义的酯，酰胺或氨基甲酸酯的盐，可用作雌激素受体配体。

3. 发明申请

US20120202853A1 SUBSTITUTED PYRAZOLES AS ESTROGEN RECEPTOR LIGANDS 有权
标题翻译：替代吡唑作为雌激素受体配体
公开(公告)号：US20120202853A1
公开(公告)日：2012-08-09
申请号：US13500341
申请日：2010-10-06
申请人： Joakim Löfstedt , Xiongyu Wu , Lars Krüger
发明人： Joakim Löfstedt , Xiongyu Wu , Lars Krüger
IPC分类号： A61K31/4439 , A61K31/4155 , A61K31/415 , C07D231/38 , C07D413/04 , C07D403/04 , C07D405/04 , A61K31/422 , C07D401/04
CPC分类号： C07D231/12 , C07D207/416 , C07D231/38 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14
摘要： The invention provides a compound of formula (I) wherein G is a pyrazole ring as defined in the specification and R4, R5, R6 and R7 are as defined in the specification; or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity.
摘要翻译：本发明提供式（I）化合物，其中G是说明书中定义的吡唑环，R4，R5，R6和R7如说明书中所定义; 或其药学上可接受的酯，酰胺，溶剂合物或其盐，包括这种酯或酰胺的盐，以及这种酯，酰胺或盐的溶剂合物。本发明还提供了这样的化合物在治疗或预防与与雌激素受体活性相关的疾病或病症相关的病症中的用途。

4. 发明授权

US08653112B2 Substituted pyrazoles as estrogen receptor ligands 有权
公开(公告)号：US08653112B2
公开(公告)日：2014-02-18
申请号：US13500341
申请日：2010-10-06
申请人： Joakim Löfstedt , Xiongyu Wu , Lars Krüger
发明人： Joakim Löfstedt , Xiongyu Wu , Lars Krüger
IPC分类号： A61K31/4439 , A61K31/4155 , A61K31/415 , C07D231/38 , C07D413/04 , C07D403/04 , C07D405/04 , A61K31/422 , C07D401/04
CPC分类号： C07D231/12 , C07D207/416 , C07D231/38 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14
摘要： The invention provides a compound of formula (I) wherein G is a pyrazole ring as defined in the specification and R4, R5, R6 and R7 are as defined in the specification; or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity.

5. 发明授权

US08005261B2 Model-based object classification and target recognition 有权
标题翻译：基于模型的对象分类和目标识别
公开(公告)号：US08005261B2
公开(公告)日：2011-08-23
申请号：US10488927
申请日：2002-09-16
申请人： Henrik Baur , Helmuth Eggers , Lars Krüger , Rainer Ott
发明人： Henrik Baur , Helmuth Eggers , Lars Krüger , Rainer Ott
IPC分类号： G06K9/00
CPC分类号： G06K9/325
摘要： Method for at least one of model-based classification and target recognition of an object. The method includes recording an image of an inanimate object, determining a feature that represents a part of the inanimate object, determining at least one condition associated with the feature that indicates an applicability of the feature based on at least one of geometry of the object, distance of the object from a camera, illumination conditions, contrast, speed of the object, height of the object, and relative position of the object to a camera, and carrying out the at least one of classification and target recognition of the object by recording the feature when the at least one condition indicates the applicability of the feature. At least one of object classification and target recognition is carried out for a feature of the object that is visible and recordable according to the position of the object. The recording, the determining the feature, the determining the at least one condition, and the carrying out are implemented on a computer.
摘要翻译：用于对象的基于模型的分类和目标识别中的至少一个的方法。该方法包括记录无生物对象的图像，确定表示无生物对象的一部分的特征，基于对象的几何形状确定指示特征的适用性的与特征相关联的至少一个条件，物体与相机的距离，照明条件，对比度，物体的速度，物体的高度以及物体相对于相机的相对位置，以及通过记录来执行对象的分类和目标识别中的至少一个当所述至少一个条件指示所述特征的适用性时的所述特征。根据对象的位置，对于可见和可记录的对象的特征，执行对象分类和目标识别中的至少一个。在计算机上实现记录，确定特征，确定至少一个条件和执行。

6. 发明申请

US20090326018A1 2-Phenyl indene derivatives useful as estrogen receptor ligands 审中-公开
标题翻译：可用作雌激素受体配体的2-苯基茚衍生物
公开(公告)号：US20090326018A1
公开(公告)日：2009-12-31
申请号：US12311722
申请日：2007-10-12
申请人： Henrik Jernstedt , Lars Krüger , Patrik Rhönnstad , Daniel Nöteberg
发明人： Henrik Jernstedt , Lars Krüger , Patrik Rhönnstad , Daniel Nöteberg
IPC分类号： A61K31/425 , C07D307/02 , A61K31/341 , C07D233/90 , A61K31/4164 , C07C39/12 , A61K31/05 , C07D277/20
CPC分类号： C07D333/16 , C07C37/002 , C07C37/055 , C07C37/18 , C07C39/23 , C07C39/42 , C07C43/20 , C07C43/23 , C07C45/00 , C07C45/30 , C07C45/44 , C07C45/46 , C07C45/65 , C07C45/67 , C07C45/673 , C07C45/68 , C07C45/74 , C07C47/57 , C07C47/575 , C07C49/747 , C07C49/755 , C07C49/84 , C07C255/53 , C07C2602/08 , C07D207/333 , C07D231/12 , C07D233/64 , C07D233/90 , C07D277/24 , C07D307/46 , C07D307/54 , C07D333/24
摘要： The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined in the specification, and wherein either the bond between the C1 and C2 carbon atoms is a double bond or the bond between the C2 and C3 carbon atoms is a double bond, R2 being absent when the bond between the C1 and C2 carbon atoms is a double bond.
摘要翻译：本发明提供式（I）化合物或其药学上可接受的酯，酰胺，溶剂化物或其盐，包括这种酯或酰胺的盐，以及这种酯，酰胺或盐的溶剂合物。本发明还提供了这样的化合物在治疗或预防与雌激素受体活性相关的疾病或病症相关的病症中的用途。式（I）其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 10，R 11和R 12如说明书中所定义，并且其中C 1和C 2碳原子之间的键为双键或C2和C3之间的碳原子之间的键是双键，当C1和C2的碳原子之间的键是双键时，R2不存在。

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