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    • 1. 发明授权
    • Imidazopyridine compounds as 5-HT4 receptor modulators
    • 咪唑并吡啶化合物作为5-HT4受体调节剂
    • US06624162B2
    • 2003-09-23
    • US10251109
    • 2002-09-20
    • Chikara UchidaHirohide NoguchiAlan StobieGeoffrey GymerDavid Fenwick
    • Chikara UchidaHirohide NoguchiAlan StobieGeoffrey GymerDavid Fenwick
    • A61K31437
    • C07D471/04
    • This invention provides a compound of the formula (I): or the pharmaceutically acceptable salts thereof wherein R1 is hydrogen, halo or alkyl; R2 and R3 are independently hydrogen, alkyl, alkenyl, alkynyl, aminoalkyl or hydroxyalkyl; or R2 and R3 taken together with the nitrogen atom to which they are attached may form hetrocyclic; R4 is hydrogen, halo, acyl, amino, amido, aryl, arylalkyl, or heteroaryl; R5 is hydrogen, halo, alkyl alkenyl, alkynyl, acyl, amino, amido, aryl, arylalkyl, or heteroaryl; R6 is hydrogen, alkyl or alkoxyalkyl; X is NR9 wherein R9 is hydrogen or alkyl; and Y is (CR7R8)n wherein n is an integer from 0 to 5. These compounds have 5-HT4 receptor binding activity, and thus are useful for the treatment of gastroesophageal reflux disease, non-ulcer dyspepsia, Functional dyspepsia, irritable bowel syndrome or the like in mammalian, especially humans. This invention also provides a pharmaceutical composition comprising the above compound.
    • 本发明提供式(I)化合物或其药学上可接受的盐,其中R 1是氢,卤素或烷基; R 2和R 3独立地是氢,烷基,烯基,炔基,氨基烷基或羟烷基; 或R 2和R 3与它们所连接的氮原子一起可以形成环状的; R 4是氢,卤素,酰基,氨基,酰氨基,芳基,芳基烷基或杂芳基; R 5是氢,卤素,烷基烯基,炔基,酰基,氨基,酰氨基,芳基,芳基烷基或杂芳基; R 6是氢,烷基或烷氧基烷基; X是NR 9,其中R 9是氢或烷基; 并且Y是(CR 7 R 8)n,其中n是0至5的整数。这些化合物具有5-HT 4受体结合活性,因此可用于治疗胃食管反流病,非溃疡性消化不良 ,功能性消化不良,肠易激综合征等。 本发明还提供了包含上述化合物的药物组合物。
    • 3. 发明申请
    • Apparatus for providing optical communication between integrated circuits of different PC boads and an integrated circuit assembly for use therein
    • 用于在不同PC机的集成电路之间提供光通信的装置和用于其中的集成电路组件
    • US20060034560A1
    • 2006-02-16
    • US10915641
    • 2004-08-10
    • Terrel MorrisDavid FenwickRichard LuebsDuane WegherJeffrey Yetter
    • Terrel MorrisDavid FenwickRichard LuebsDuane WegherJeffrey Yetter
    • G02B6/12G02B6/26G02B6/08
    • G02B6/43H05K1/0274H05K1/182H05K2201/10121H05K2201/10734
    • Optical communication apparatus comprises: a first IC assembly disposed at a first PCB and comprising: a first IC package electrically coupled to circuits of the first PCB and having an opening in a bottom layer thereof; a first array of optical elements disposed in and electrically coupled to the first IC package and aligned with the bottom layer opening; and a tube of optical fibers disposed in the bottom layer opening with one end aligned under the first array and another end protruding out from the bottom layer of the first package and extending through a hole in the first PCB; a second IC assembly disposed at a second PCB, arranged in parallel with the first PCB, and comprising: a second IC package electrically coupled to circuits of the second PCB and having an opening in a top layer thereof; and a second array of optical elements disposed at the second IC package and electrically coupled thereto through the top layer opening; and wherein the second array being optically aligned with the optical fiber tube of the first IC package to accommodate optical communication between the arrays through the optical fibers of the tube. Various other embodiments of the apparatus are also disclosed.
    • 光通信装置包括:第一IC组件,其设置在第一PCB处,包括:第一IC封装,电耦合到第一PCB的电路并且在其底层中具有开口; 第一阵列的光学元件设置在电耦合到第一IC封装并与底层开口对准; 以及设置在底层开口中的光纤管,其一端在第一阵列下方对准,另一端从第一封装的底层突出并延伸穿过第一PCB中的孔; 设置在与所述第一PCB平行的第二PCB处的第二IC组件,包括:电耦合到所述第二PCB的电路并且在其顶层中具有开口的第二IC封装; 以及第二阵列的光学元件,其设置在所述第二IC封装处并且通过所述顶层开口与其电耦合; 并且其中所述第二阵列与所述第一IC封装的所述光纤管光学对准,以适应所述阵列之间通过所述管的光纤的光学连通。 还公开了该装置的各种其它实施例。
    • 8. 发明授权
    • Pattern recognition system having inter-pattern spacing correction
    • 具有图案间距校正的图案识别系统
    • US5161245A
    • 1992-11-03
    • US694527
    • 1991-05-01
    • David Fenwick
    • David Fenwick
    • G06K9/36G06F17/27G06K9/62G06K9/72
    • G06F17/273G06K9/72G06K2209/01
    • A pattern recognition system having inter-pattern spacing correction is disclosed which recognizes words and determines where to place spaces between those words by (a) storing each input character in one or more buffers in memory, (b) comparing the last entry of each buffer against a dictionary of known words, (c) copying last entries which match words to new buffers and placing a space after the last entry in the old buffer, (d) deleting a buffer when a last entry from that buffer does not at least match the beginning of a known word in the dictionary, (e) repeating steps (a) through (d) until all the buffers have been deleted or until an end character, such as a carriage return or period has been stored in each buffer, (f) again comparing the last entries from each buffer to the dictionary and deleting any buffer having a last entry which is not a known word in the dictionary or which does not end with a space followed by an end character, and (g) saving and/or outputting the remaining words. Common words which appear in each buffer, and have therefore been positively identified, can be saved or output to reduce the size of each buffer at any point in the process. Words can either be output in the longest possible combined form or in shorter segmented forms as desired by a user.
    • 公开了一种具有图案间距校正的图案识别系统,其通过(a)将每个输入字符存储在存储器中的一个或多个缓冲器中,(b)比较每个缓冲器的最后一个条目,识别字并确定在这些字之间放置空格的位置 针对已知单词的字典,(c)将与单词匹配的最后的条目复制到新的缓冲区,并在旧缓冲区中的最后一个条目之后放置一个空格;(d)当从该缓冲器的最后一个条目至少匹配时删除一个缓冲区 字典中的已知字的开始,(e)重复步骤(a)至(d),直到所有缓冲器已经被删除或直到诸如回车或周期的结束字符已经存储在每个缓冲器中 f)再次将来自每个缓冲器的最后一个条目与字典进行比较,并且删除具有最后条目的任何缓冲器,该最后条目在字典中不是已知的字,或者不以结尾字符后面的空格结尾,以及(g) /或输出保留 的话。 可以保存或输出出现在每个缓冲区中并因此得到肯定识别的常用单词,以减少过程中任何一点的每个缓冲区的大小。 单词可以以最长可能的组合形式输出,也可以按照用户所期望的较短的分段形式输出。
    • 10. 发明申请
    • Apparatus and method of providing an optical connection between PC boards for optical communication
    • 在用于光通信的PC板之间提供光连接的装置和方法
    • US20060062528A1
    • 2006-03-23
    • US10945007
    • 2004-09-20
    • Terrel MorrisDavid FenwickRichard LuebsDuane WegherJeffry Yetter
    • Terrel MorrisDavid FenwickRichard LuebsDuane WegherJeffry Yetter
    • G02B6/36G02B6/00
    • G02B6/43G02B6/3897G02B6/4249G02B6/4292
    • Apparatus for connecting an interconnecting cable between first and second printed circuit (PC) boards comprises: a base member disposed on a side of the first PC board for fixedly attaching one end of the interconnecting cable to the first PC board; a first connector attached to the other end of the interconnecting cable; a second connector disposed on a side of the second PC board; and a spring member attached to the base member for supporting the first connector away from the side of the first PC board, the spring member operative to force the first connector against the side of the second PC board to cause slidable engagement of the first and second connectors when one of the first and second PC boards is slid past the other of the first and second PC boards. Apparatus and method of providing optical connection between a first optical array electrically coupled to a first printed circuit (PC) board and a second optical array electrically coupled to a second PC board for providing optical communication between the first and second optical arrays are also disclosed.
    • 用于在第一和第二印刷电路板(PC)板之间连接互连电缆的装置包括:设置在第一PC板的一侧的基座部件,用于将互连电缆的一端固定地连接到第一PC板; 连接到所述互连电缆的另一端的第一连接器; 第二连接器,设置在所述第二PC板的一侧; 以及弹簧构件,其附接到所述基座构件,用于支撑所述第一连接器远离所述第一PC板的侧面,所述弹簧构件可操作以迫使所述第一连接器抵靠所述第二PC板的侧面,以引起所述第一和第二 连接器,其中第一和第二PC板之一滑动通过第一和第二PC板中的另一个。 还公开了在电耦合到第一印刷电路(PC)板的第一光学阵列和电耦合到第二PC板的第二光学阵列之间提供光学连接的设备和方法,用于在第一和第二光学阵列之间提供光学通信。