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1. 发明授权

US5756505A N-acylpiperazine derivative, antibacterial drug and anti-ulcer drug 失效
标题翻译： N-酰基哌嗪衍生物，抗菌药物和抗溃疡药
公开(公告)号：US5756505A
公开(公告)日：1998-05-26
申请号：US625992
申请日：1996-04-01
申请人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima , Koji Kobayashi
发明人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima , Koji Kobayashi
IPC分类号： C07D295/18 , A61K31/495 , A61P1/04 , A61P31/04 , C07D295/185 , C07D295/192 , C07D295/205 , C07D405/12
CPC分类号： C07D295/185 , C07D295/192
摘要： An N-acylpiperazine derivative or a salt thereof in accordance with the present invention is represented by the following formula 1: ##STR1## wherein R.sub.1 represents a lower alkyl, hydroxy lower alkyl, lower acyl, or arylcarbonyloxy lower alkyl group; R.sub.2 represents hydrogen atom or a lower alkyl, lower alkoxy, lower alkenyl, amino, or nitro group; R.sub.3 and R.sub.4, which are identical to or different from each other, represent hydrogen atoms, halogen atoms, or cyano, nitro, lower alkyl, or lower alkoxy groups; and n represents 0 or 1. The N-acylpiperazine derivative has anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulsers.
摘要翻译：根据本发明的N-酰基哌嗪衍生物或其盐由下式1表示：其中R 1表示低级烷基，羟基低级烷基，低级酰基或芳基羰基氧基低级烷基; R2代表氢原子或低级烷基，低级烷氧基，低级烯基，氨基或硝基; R 3和R 4彼此相同或不同，表示氢原子，卤原子或氰基，硝基，低级烷基或低级烷氧基; 并且n表示0或1. N-酰基哌嗪衍生物具有抗溃疡作用或对幽门螺杆菌具有抗菌活性，可用于预防或治愈酏剂。

2. 发明授权

US5859032A Pyridine derivative, anti-ulcer drug, and antibacterial drug 失效
标题翻译：吡啶衍生物，抗溃疡药和抗菌药
公开(公告)号：US5859032A
公开(公告)日：1999-01-12
申请号：US818281
申请日：1997-03-17
申请人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
发明人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
IPC分类号： A61K31/44 , A61K31/4409 , A61K31/4418 , A61P1/04 , C07D213/40 , C07D213/70 , C07D213/74 , C07D213/75 , C07D213/76 , C07D213/81
CPC分类号： C07D213/40 , C07D213/70 , C07D213/74 , C07D213/75
摘要： A pyridine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein W represents a group expressed by the following formula 2 or formula 3; ##STR2## wherein R.sub.1 represents an alkenyloxy group;n represents 1 or 2;Ra represents a lower alkyl group; andRb represents a halogen atom; and whereineach of R.sub.2 and R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group;Y represents a group expressed by --S--, --NH-- or --CONH--;m represents an integer of 0 to 2; andp represents 0 or 1.The pyridine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.
摘要翻译：由下式1表示的吡啶衍生物或其盐：其中W表示由下式2或式3表示的基团; 式3其中R1表示烯氧基; n表示1或2; Ra表示低级烷基; 并且R b表示卤原子; 并且其中R 2和R 3各自表示氢原子，低级烷基，低级烷氧基或卤代烷基; Y表示由-S-，-NH-或-CONH-表示的基团; m表示0〜2的整数。并且p表示0或1.吡啶衍生物对抗幽门螺杆菌具有抗溃疡作用或抗菌活性，可用于预防或治愈溃疡。

3. 发明授权

US6001880A Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug 失效
标题翻译：烷二胺衍生物，抗溃疡药和抗菌药
公开(公告)号：US6001880A
公开(公告)日：1999-12-14
申请号：US53667
申请日：1998-04-02
申请人： Chikao Nishino , Tomohiro Uetake , Nao Kojima , Hirotada Fukunishi , Fumitaka Sato
发明人： Chikao Nishino , Tomohiro Uetake , Nao Kojima , Hirotada Fukunishi , Fumitaka Sato
IPC分类号： A61K31/165 , A61K31/44 , A61P1/04 , A61P31/04 , C07C233/78 , C07C235/50 , C07C235/60 , C07C235/84 , C07C237/34 , C07C237/42 , C07C323/62 , C07D213/81 , C07D213/82 , C07D295/155 , A01N37/18 , C07C233/74
CPC分类号： C07D213/81 , C07C233/78 , C07C235/50 , C07C235/60 , C07C235/84 , C07C237/34 , C07C237/42 , C07C323/62 , C07D213/82 , C07D295/155
摘要： An alkylenediamine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein each of R.sub.1 and R.sub.2 represents a lower alkyl group, and W represents a group expressed by any of the following formulas 2 and 3; ##STR2## wherein all variables are as defined in the specification The alkylenediamine derivative has an anti- ulcer effect or an antibacterial activity against Helicobacter pyroli, and has also high safety to be available for prevention or cure of ulcers.
摘要翻译：由下式1表示的亚烷基二胺衍生物或其盐：其中R 1和R 2各自表示低级烷基，W表示由下式2和3中任一个表示的基团; 其中所有变量如本说明书中所定义。亚烷基二胺衍生物对幽门螺杆菌具有抗溃疡作用或抗菌活性，并且还具有可用于预防或治愈溃疡的高安全性。

4. 发明授权

US6017937A Pyridine derivative, anti-ulcer drug, and antibacterial drug 失效
标题翻译：吡啶衍生物，抗溃疡药和抗菌药
公开(公告)号：US6017937A
公开(公告)日：2000-01-25
申请号：US55921
申请日：1998-04-07
申请人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
发明人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
IPC分类号： A61K31/44 , A61K31/4409 , A61K31/4418 , A61P1/04 , C07D213/40 , C07D213/70 , C07D213/74 , C07D213/75 , C07D213/76 , C07D213/81
CPC分类号： C07D213/40 , C07D213/70 , C07D213/74 , C07D213/75
摘要： A pyridine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein W represents a group expressed by the following formula 2 or formula 3; ##STR2## wherein R.sub.1 represents an alkenyloxy group; n represents 1 or 2;Ra represents a lower alkyl group; andRb represents a halogen atom; and whereineach of R.sub.2 and R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group;Y represents a group expressed by --S--, --NH-- or --CONH--;m represents an integer of 0 to 2; andp represents 0 or 1.The pyridine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.
摘要翻译：由下式1表示的吡啶衍生物或其盐：其中W表示由下式2或式3表示的基团; 其中R1表示烯氧基; n表示1或2; Ra表示低级烷基; 并且R b表示卤原子; 并且其中R 2和R 3各自表示氢原子，低级烷基，低级烷氧基或卤代烷基; Y表示由-S-，-NH-或-CONH-表示的基团; m表示0〜2的整数。并且p表示0或1.吡啶衍生物对抗幽门螺杆菌具有抗溃疡作用或抗菌活性，可用于预防或治愈溃疡。

5. 发明授权

US5912258A Thiadiazoleamide derivative and anti-ulcer drug 有权
标题翻译：噻二唑衍生物和抗溃疡药
公开(公告)号：US5912258A
公开(公告)日：1999-06-15
申请号：US157376
申请日：1998-09-21
申请人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
发明人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
IPC分类号： C07D285/12 , C07D285/135 , C07D417/12 , C07D289/135 , A61K31/41
CPC分类号： C07D285/135 , C07D417/12
摘要： A thiadiazoleamide derivative or a salt thereof expressed by the following Formula 1: ##STR1## wherein each of R.sub.1 and R.sub.2 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylamino group or an alkenyloxy group; wherein when either R.sub.1 or R.sub.2 is a hydrogen atom, the other is not a hydrogen atom; R.sub.3 represents a lower alkyl group, an aryl group, a pyridyl group or --N(R.sub.4)R.sub.5, wherein R.sub.4 and R.sub.5 represent lower alkyl groups or together represent a saturated heterocyclic ring having 4-8 members; wherein when R.sub.1 or R.sub.2 is a lower alkoxy group, R.sub.3 is --N(R.sub.4)R.sub.5 or a pyridyl group; and n represents an integer of 1-3. The derivatives have anti-ulcer effect to be available for preventing or curing ulcers in mammals.
摘要翻译：由下式1表示的噻二唑衍生物或其盐：其中R 1和R 2各自表示氢原子，低级烷基，低级烷氧基，低级烷基氨基或烯氧基; 其中当R 1或R 2是氢原子时，另一个不是氢原子; R3表示低级烷基，芳基，吡啶基或-N（R4）R5，其中R4和R5代表低级烷基或一起代表具有4-8个成员的饱和杂环; 其中当R1或R2为低级烷氧基时，R3为-N（R4）R5或吡啶基; n表示1-3的整数。该衍生物具有抗溃疡作用，可用于预防或治疗哺乳动物的溃疡。

6. 发明授权

US5814634A Alkylenediamine derivative anti-ulcer drug and antibacterial drug 失效
标题翻译：烷二胺衍生物抗溃疡药和抗菌药
公开(公告)号：US5814634A
公开(公告)日：1998-09-29
申请号：US842891
申请日：1997-04-17
申请人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
发明人： Chikao Nishino , Fumitaka Sato , Tomohiro Uetake , Hirotada Fukunishi , Nao Kojima
IPC分类号： C07D295/12 , A61K31/445 , A61K31/495 , A61K31/505 , A61K31/535 , A61K31/5375 , A61P1/04 , A61P31/04 , C07D211/14 , C07D239/42 , C07D277/20 , C07D277/38 , C07D277/82 , C07D295/13 , C07D317/58 , C07D211/32 , C07D265/30
CPC分类号： C07D295/13
摘要： The invention provides a compound which has anti-ulcer effect and antibacterial activity against Helicobacter pyroli. This compound is an alkylenediamine derivative or salt which has a general formula of (1): ##STR1## wherein each of R.sub.4, R.sub.5, and R.sub.6 is hydrogen or lower alkyl; n represents an integer of 1 to 6; Y is --CH.sub.2 --, --O--, or --N(R.sub.7)--, wherein R.sub.7 is lower alkyl, aryl, carbamoyl lower alkyl, aralkyl, or a heterocyclic group having 5 to 9 carbon numbers; and, W is a group expressed by formulas 2 or 3: ##STR2## wherein (1) in formula 2: each of R.sub.1 and R.sub.2 is hydrogen, lower alkoxy, alkenyloxy, or a halogen atom; each of R.sub.3 and R.sub.3 is methyl, prenyl, or geranyl; when one of R.sub.3 and R.sub.3 is prenyl or geranyl, the other must be a methyl group; and X is oxygen or sulfur; and (2) in formula 3, R.sub.10 is a lower alkyl, and R.sub.11 is a halogen atom.
摘要翻译：本发明提供了一种对幽门螺杆菌具有抗溃疡作用和抗菌活性的化合物。该化合物是具有通式（1）：式1的亚烷基二胺衍生物或盐，其中R 4，R 5和R 6各自为氢或低级烷基; n表示1〜6的整数， Y是-CH 2 - ， - O-或-N（R 7） - ，其中R 7是低级烷基，芳基，氨基甲酰基低级烷基，芳烷基或具有5至9个碳数的杂环基; 式3中，式（1）中，R 1和R 2各自为氢，低级烷氧基，链烯氧基或卤素原子，式中，（1）表示2或3表示的基团。 R 3和R 3各自为甲基，异戊烯基或香叶基; 当R3和R3之一是异戊烯基或香叶基时，另一个必须是甲基; X为氧或硫; 和（2）在式3中，R 10是低级烷基，R 11是卤素原子。

7. 发明授权

US5962456A N-acylpiperazine derivative, anti-ulcer drug, and antibacterial drug 失效
标题翻译： N-酰基哌嗪衍生物，抗溃疡药和抗菌药
公开(公告)号：US5962456A
公开(公告)日：1999-10-05
申请号：US939912
申请日：1997-09-29
申请人： Chikao Nishino , Fumitaka Sato , Hirotada Fukunishi
发明人： Chikao Nishino , Fumitaka Sato , Hirotada Fukunishi
IPC分类号： C07D295/10 , A61K31/495 , A61P1/04 , A61P31/04 , C07D213/72 , C07D213/79 , C07D213/80 , C07D295/14 , C07D295/192 , C07D317/58 , C07D317/60 , C07D317/68 , C07D401/04 , C07D401/12
CPC分类号： C07D295/192 , C07D213/80 , C07D317/68
摘要： An N-acylpiperazine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein R.sub.1 represents a pyridylcarbonyloxy lower alkyl group, a benzoylamino lower alkyl group, benzyl group, carbamoyl group, pyridyl group, or diphenylmethyl group;R.sub.2 represents a lower alkyl group or a lower alkoxy group;n represents an integer of 0 to 2;R.sub.3 represents a hydrogen atom, an alkenyl group, or benzyl group; andm represents an integer of 1 to 3.The N-acylpiperazine derivative or a salt thereof has an anti-ulcer effect, an antibacterial activity against Helicobacter pyroli, and high safety to be available for prevention or cure of various ulcers.
摘要翻译：由下式1表示的N-酰基哌嗪衍生物或其盐：其中R1表示吡啶基羰基氧基低级烷基，苯甲酰氨基低级烷基，苄基，氨基甲酰基，吡啶基或二苯基甲基; R2代表低级烷基或低级烷氧基; n表示0〜2的整数， R3表示氢原子，烯基或苄基; m表示1〜3的整数。N-酰基哌嗪衍生物或其盐具有抗溃疡作用，对幽门螺杆菌的抗菌活性，以及可用于预防或治愈各种溃疡的高安全性。

8. 发明授权

US6057337A 1,2-DI-substituted piperidine derivative, hair growth promoter and external composition for skin using the same 有权
标题翻译： 1,2-DI取代的哌啶衍生物，毛发生长促进剂和使用其的皮肤外用组合物
公开(公告)号：US6057337A
公开(公告)日：2000-05-02
申请号：US239960
申请日：1999-01-29
申请人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Akihiro Ishino
发明人： Koji Kobayashi , Hirotada Fukunishi , Kenichi Umishio , Akihiro Ishino
IPC分类号： C07D211/22 , C07D211/26 , C07D401/12 , C07D521/00 , A61K7/06
CPC分类号： C07D231/12 , C07D211/22 , C07D211/26 , C07D233/56 , C07D249/08 , C07D401/12
摘要： A 1,2-di-substituted piperidine derivative or a salt thereof expressed by the following Formula (I): ##STR1## wherein one of A and B is a hydrocarbon group of C.sub.1-30 expressed by R.sup.1 and the other is --(CH.sub.2)n-NR.sup.2 R.sup.3 ; Y is --CO--, --CONR.sup.5 -- or --COO--; Z is --O--, --OCO--, --OCONR.sup.6 -- or --NR.sup.6 --; R.sup.2 and R.sup.3 individually represent a hydrogen a lower alkyl, a phenyl or a benzyl group, or together represent a heterocycle having 3-7 members; --NR.sup.5 --(CH.sub.2)n-NR.sup.2 R.sup.3 and --NR.sup.6 --(CH.sub.2)n-NR.sup.2 R.sup.3 of --(Y).sub.1 --A and --Z--B may be the following Group W: ##STR2## wherein ring E is a heterocycle of 6 or 7 members including two nitrogen atoms and R.sup.2 is a hydrogen, a lower alkyl, a phenyl or a benzyl group; R.sup.4 is a hydrogen, a halogen, a lower alkyl, a lower acyl, a nitro, a cyano, a lower alkoxycarbonyl, a carbamoyl, a lower alkylcarbamoyl, a lower alkylamino, a lower acylamino, a lower alkoxy or a lower acyloxy group; each of R.sup.5 and R.sup.6 is a hydrogen, a lower alkyl, a lower acyl, a lower alkylcarbamoyl group, or a part of said ring E; l is 0 or 1; m is an integer of 2-5; and n is an integer of 0-5. The 1,2-di-substituted piperidine derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in human.
摘要翻译：由下式（I）表示的1,2-二取代的哌啶衍生物或其盐：其中A和B中的一个为由R1表示的C1-30的烃基，另一个为 - （CH 2）n - NR2R3; Y是-CO - ， - CONR 5 - 或-COO-; Z是-O - ， - OCO - ， - OCONR 6 - 或-NR 6 - ; R2和R3各自表示氢，低级烷基，苯基或苄基，或一起表示具有3-7个成员的杂环; - （Y）1-A和-ZB的-NR 5 - （CH 2）n -NR 2 R 3和-NR 6 - （CH 2）n -NR 2 R 3可以是以下W组：其中环E是6或7个成员的杂环，包括两个氮原子，R 2为氢，低级烷基，苯基或苄基; R4是氢，卤素，低级烷基，低级酰基，硝基，氰基，低级烷氧基羰基，氨基甲酰基，低级烷基氨基甲酰基，低级烷基氨基，低级酰基氨基，低级烷氧基或低级酰氧基。 R5和R6各自为氢，低级烷基，低级酰基，低级烷基氨基甲酰基或所述环E的一部分; l为0或1; m为2-5的整数; n为0-5的整数。 1,2-二取代的哌啶衍生物或其盐具有优异的毛发生长和再生长促进效果，其可用于哺乳动物，特别是人的护发，改善或预防脱发。

9. 发明授权

US5972929A Quinazolinone derivative, hair growth promoter and external composition for skin using the same 有权
标题翻译：喹唑啉酮衍生物，毛发生长促进剂和皮肤外用组合物
公开(公告)号：US5972929A
公开(公告)日：1999-10-26
申请号：US137148
申请日：1998-08-20
申请人： Koji Kobayashi , Hirotada Fukunishi , Tsunao Magara
发明人： Koji Kobayashi , Hirotada Fukunishi , Tsunao Magara
IPC分类号： A61K8/49 , A61Q7/00 , C07D239/90 , A61K31/495
CPC分类号： C07D239/90 , A61K8/4953 , A61Q7/00
摘要： A quinazolinone derivative or a salt thereof expressed by the following Formula (I); ##STR1## wherein each of A and B is R.sup.1 or --(CH.sub.2).sub.n -NR.sup.2 R.sup.3 ; wherein R.sup.1 represents a hydrocarbon group of C.sub.10-30 ; wherein R.sup.2 and R.sup.3 individually represent a hydrogen atom, a lower alkyl group, a phenyl group, or a benzyl group, or together represent a heterocyclic ring having 3-7 members; and n represents an integer of 1-5; wherein when A is R.sup.1, B is --(CH.sub.2).sub.n -NR.sup.2 R.sup.3 and when A is --(CH.sub.2).sub.n -NR.sup.2 R.sup.3, B is R.sup.1 ; and wherein R.sup.4 is selected from the group consisting of a hydrogen atom, a halogen atom, a lower alkyl group, a lower acyl group, a nitro group, a cyano group, an amino group, a lower alkoxycarbonyl group, a lower alkylamino group, a lower alkoxy group, a lower acyloxy group, a carbamoyl group, a lower alkylcarbamoyl group, and a lower acylamino group. The quinazolinone derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in humans.
摘要翻译：由下式（I）表示的喹唑啉酮衍生物或其盐; 其中A和B各自为R 1或 - （CH 2）n -NR 2 R 3; 其中R1表示C10-30的烃基; 其中R2和R3各自表示氢原子，低级烷基，苯基或苄基，或一起表示具有3-7个成员的杂环; n表示1-5的整数，其中当A为R1时，B为 - （CH2）n-NR2R3，当A为 - （CH2）n-NR2R3时，B为R1; 并且其中R 4选自氢原子，卤素原子，低级烷基，低级酰基，硝基，氰基，氨基，低级烷氧基羰基，低级烷基氨基，低级烷氧基，低级酰氧基，氨基甲酰基，低级烷基氨基甲酰基和低级酰氨基。喹唑啉酮衍生物或其盐具有优异的毛发生长和再生长促进作用，其可用于哺乳动物，特别是人类的护发，改善或预防脱发。

10. 发明授权

US06339154B1 (2-Substituted oxyphenyl) alkanamide derivative, hair growth promoter and external composition for skin using the same 失效
标题翻译：（2-取代的氧基苯基）烷酰胺衍生物，毛发生长促进剂和使用其的皮肤外用组合物
公开(公告)号：US06339154B1
公开(公告)日：2002-01-15
申请号：US09496258
申请日：2000-02-01
申请人： Koji Kobayashi , Hirotada Fukunishi , Tokuro Iwabuchi
发明人： Koji Kobayashi , Hirotada Fukunishi , Tokuro Iwabuchi
IPC分类号： C07D24104
CPC分类号： C07D295/185 , A61K8/42 , A61K8/445 , A61K8/4926 , A61K8/494 , A61Q7/00 , C07C235/34 , C07C271/44 , C07C271/52 , C07C271/64 , C07C271/66 , C07C281/02 , C07D295/088 , C07D295/13 , C07D295/205
摘要： A (2-substituted oxyphenyl)alkanamide derivative or a salt thereof expressed by the following Formula (I): wherein one of A and B is a hydrocarbon group of C3-30 expressed by R1 and the other is —(CH2)n—NR2R3; Z is —CO— or —CONR6—; R2 and R3 individually represent H, lower alkyl or benzyl, or —NR2R3 may be a heterocycle having 3-7 members; wherein —CONR5—(CH2)n—NR2R3 or —CONR6—(CH2)n—NR2R3 may be the following Group (D): wherein ring Y is a heterocycle of 6 or 7 members; R4 is selected from the group consisting of H, halogen, lower alkyl, lower acyl and etc; R5 and R6 are individually H, lower alkyl, lower acyl or lower alkylcarbamoyl, or may form a part of said Group(II); 1 is 0 or 1; m is 1 or 2; and n is an integer of 0-5. The (2-substituted oxyphenyl)alkanamide derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in human.
摘要翻译：由下式（I）表示的（2-取代的氧苯基）烷酰胺衍生物或其盐：其中A和B中的一个是由R 3表示的C3-30的烃基，另一个是 - （CH 2）n -NR 2 R 3 ; Z是-CO-或-CONR 6 - ; R2和R3各自表示H，低级烷基或苄基，或-NR2R3可以是具有3-7个成员的杂环; 其中-CONR 5 - （CH 2）n -NR 2 R 3或-CONR 6 - （CH 2）n -NR 2 R 3可以是下列基团（D）：其中环Y是6或7个成员的杂环; R4选自H，卤素，低级烷基，低级酰基等; R5和R6各自为H，低级烷基，低级酰基或低级烷基氨基甲酰基，或可形成所述组（II）的一部分。 1为0或1; m为1或2; n为0-5的整数。（2-取代的氧苯基）烷酰胺衍生物或其盐具有优异的毛发生长和再生长促进作用，其可用于哺乳动物，特别是人的护发，改善或预防脱发。

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