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    • 3. 发明申请
    • FIBER STRUCTURES AND PROCESS FOR THEIR PREPARATION
    • 纤维结构及其制备方法
    • US20110180951A1
    • 2011-07-28
    • US12441072
    • 2007-09-18
    • Wee Eong TeoKwan-Ho Casey ChanKazutoshi FujiharaSeeram RamakrishnaSusan Liao
    • Wee Eong TeoKwan-Ho Casey ChanKazutoshi FujiharaSeeram RamakrishnaSusan Liao
    • B27N3/04B28B13/00
    • A61L27/38D01D5/0046
    • There is provided a process of preparing at least one fiber structure comprising: (a) contacting at least one viscous material with at least one non-solvent, the non-solvent having a first flow rate; and (b) allowing formation of the fiber structure in the presence of the non-solvent at a second flow rate, wherein the second flow rate is less than the first flow rate or is about zero. There is provided a process of preparing at least one fiber structure, wherein the fiber structure is a fiber scaffold, comprising: (a) contacting at least one viscous material with at least one non-solvent, the non-solvent having a first flow rate; and (b) obtaining at least one fiber and assembling the obtained fiber(s), or allowing the obtained fiber(s) to be assembled, in the form of a fiber scaffold. There is also provided a fiber structure obtainable by any process according to the invention and an apparatus for preparing a fiber structure.
    • 提供了一种制备至少一种纤维结构的方法,包括:(a)使至少一种粘性材料与至少一种非溶剂接触,所述非溶剂具有第一流速; 和(b)允许在第二流量下在非溶剂存在下形成纤维结构,其中第二流量小于第一流速或约为零。 提供了制备至少一种纤维结构的方法,其中纤维结构是纤维支架,其包括:(a)使至少一种粘性材料与至少一种非溶剂接触,所述非溶剂具有第一流速 ; 和(b)以纤维骨架的形式获得至少一种纤维并组装所获得的纤维,或者使得到的纤维被组装。 还提供了可通过根据本发明的任何方法获得的纤维结构和用于制备纤维结构的设备。
    • 8. 发明申请
    • Production of nano-sized hydroxyapatite particles
    • 生产纳米级羟基磷灰石颗粒
    • US20050226939A1
    • 2005-10-13
    • US10819858
    • 2004-04-07
    • Murugan RamalingamSeeram Ramakrishna
    • Murugan RamalingamSeeram Ramakrishna
    • A61B5/055A61K33/42
    • A61K33/42C01B25/32
    • Nano-sized hydroxyapatite particles are formed in a method comprising the steps of preparing a reaction solution containing a mixture of calcium ions and phosphate ions, stirring the reaction solution at a defined stirring speed, at a defined pH range and at a defined temperature range to form a suspension of hydroxyapatite seed particles, and subjecting the suspension of hydroxyapatite particles to microwave radiation for a defined time period, while maintaining the stirring speed, to form a suspension of nano-sized hydroxyapatite particles. The suspension of hydroxyapatite particles may preferably be aged for a period of time prior to the microwave radiation.
    • 在包括以下步骤的方法中形成纳米尺寸的羟基磷灰石颗粒,所述方法包括以下步骤:制备含有钙离子和磷酸根离子的混合物的反应溶液,在规定的搅拌速度下,在规定的pH范围和在规定的温度范围内搅拌反应溶液, 形成羟基磷灰石种子颗粒的悬浮液,并且在保持搅拌速度的同时使羟基磷灰石颗粒的悬浮液在规定的时间内进行微波辐射,以形成纳米尺寸的羟基磷灰石颗粒的悬浮液。 羟基磷灰石颗粒的悬浮液可优选在微波辐射之前老化一段时间。