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1. 发明授权

US06721386B2 Method and apparatus of cardiac CT imaging using ECG and mechanical motion signals 有权
标题翻译：使用心电图和机械运动信号进行心脏CT成像的方法和装置
公开(公告)号：US06721386B2
公开(公告)日：2004-04-13
申请号：US10063066
申请日：2002-03-15
申请人： Cherik Bulkes , Gopal B. Avinash , Tin-su Pan
发明人： Cherik Bulkes , Gopal B. Avinash , Tin-su Pan
IPC分类号： A61B600
CPC分类号： A61B6/541 , A61B5/1102 , A61B6/503 , A61B6/504 , A61B6/507
摘要： The present invention is directed to a method and apparatus of cardiac CT imaging. The present invention utilizes ECG signals as well as mechanical motion signals of a cardiac region of a subject to correlate CT data acquired of the subject with the phases of the subject's cardiac region. The present invention contemplates measuring mechanical gatings of the heart by measuring changes in pressure, sound, or blood flow acceleration within the cardiac region. The mechanical gatings are then used with ECG data to correlate acquired imaging data with phases of the cardiac region for subsequent image reconstruction.
摘要翻译：本发明涉及心脏CT成像的方法和装置。本发明利用对象的心脏区域的ECG信号以及机械运动信号，将被摄体的CT数据与受试者心脏区域的相位相关联。本发明考虑通过测量心脏区域内的压力，声音或血流加速度的变化来测量心脏的机械选通。然后将机械门控与ECG数据一起使用，以将所获取的成像数据与心脏区域的相位相关联用于随后的图像重建。

2. 发明授权

US08064983B2 Method and system for prospective gating using multiple inputs 有权
标题翻译：使用多种投入的前瞻性门控的方法和系统
公开(公告)号：US08064983B2
公开(公告)日：2011-11-22
申请号：US10723716
申请日：2003-11-26
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/05
CPC分类号： A61B6/541 , A61B5/0037 , A61B5/04 , A61B5/055 , A61B5/1107 , A61B5/113 , A61B5/721 , A61B5/7289 , A61B5/7292 , A61B6/5288
摘要： One or more techniques are provided for determining the overall motion of an organ of interest relative to a viewer or imager. Motion data is acquired for the organ of interest and/or for one or more proximate organs using sensor-based and/or image data-based techniques. The sensor-based techniques may include electrical and non-electrical techniques. The image data-based techniques may include both pre-acquisition and acquisition image data. The motion data for the organ of interest and proximate organs may be used to determine one or more quiescent periods corresponding to intervals of minimal motion for the organ of interest and the proximate organs. The one or more quiescent periods may be used to determine one or more gating points that may be used prospectively, i.e., during image acquisition. In addition, the one or more quiescent periods may be used to determine one or more motion compensation factors that may be used during processing and reconstruction of the acquired image data. The gating points and motion compensation factors may be used, separately or together, to reduce motion-related artifacts in the reconstructed images.
摘要翻译：提供了一种或多种技术来确定感兴趣的器官相对于观看者或成像器的整体运动。使用基于传感器和/或图像数据的技术为感兴趣的器官和/或对于一个或多个近端器官获取运动数据。基于传感器的技术可以包括电气和非电气技术。基于图像数据的技术可以包括预采集和采集图像数据。感兴趣的器官和邻近器官的运动数据可用于确定对应于感兴趣器官和最近器官的最小运动的间隔的一个或多个静止期。可以使用一个或多个静止周期来确定可以预期使用的即一个图像采集期间的一个或多个门控点。此外，一个或多个静止周期可以用于确定在所获取的图像数据的处理和重建期间可以使用的一个或多个运动补偿因子。门控点和运动补偿因子可以单独地或一起使用以减少重建图像中的运动相关假象。

3. 发明授权

US08064979B2 Tempero-spatial physiological signal detection method and apparatus 有权
标题翻译：空间生理信号检测方法及装置
公开(公告)号：US08064979B2
公开(公告)日：2011-11-22
申请号：US10457344
申请日：2003-06-09
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/05
CPC分类号： A61B5/113 , A61B5/1107 , A61B5/7285 , A61B6/541 , A61B8/543 , A61B2562/02 , A61B2562/0219 , A61B2562/046 , A61B2562/164 , G06F19/00
摘要： A technique for measuring and characterizing the motion of an internal organ is provided. The technique includes using two or more motion-sensitive sensors, disposed on a patient in a region of interest proximate to the internal organ, which acquire motion data along the surface of the patient. The motion data may then be processed and displayed to depict or characterize the mechanical motion undergone by the internal organ. The mechanical motion may be displayed as an image or video. In addition, the mechanical motion data may be combined with other measured data, such as electrical or acoustic data, or with images acquired by other imaging modalities to generate a composite image.
摘要翻译：提供了一种用于测量和表征内脏器官运动的技术。该技术包括使用两个或更多个运动敏感传感器，其布置在靠近内脏的感兴趣区域中的患者身上，其沿着患者的表面获取运动数据。然后可以处理和显示运动数据以描绘或表征内部器官所经历的机械运动。机械运动可以显示为图像或视频。此外，机械运动数据可以与其他测量数据（例如电气或声学数据）或与其他成像模态获取的图像组合以生成合成图像。

4. 发明授权

US06574304B1 Computer aided acquisition of medical images 有权
标题翻译：计算机辅助获取医学图像
公开(公告)号：US06574304B1
公开(公告)日：2003-06-03
申请号：US10242975
申请日：2002-09-13
申请人： Jiang Hsieh , Gopal B. Avinash , Cherik Bulkes , John M. Sabol
发明人： Jiang Hsieh , Gopal B. Avinash , Cherik Bulkes , John M. Sabol
IPC分类号： A61B600
CPC分类号： A61B6/542 , A61B6/032 , A61B6/5235 , A61B6/5247 , A61B6/545 , G06F19/00 , G06T7/0012 , Y10S378/901
摘要： The invention provides a technique for acquiring subsequent image data in a medical diagnostic context based upon analysis of initial image data. The initial image data is processed via a computer aided diagnosis algorithm to determine whether additional image data acquisition is appropriate. Subsequent acquisition processes may be performed on the same imaging system from which the initial image data originated, or a different imaging system. The imaging systems may also be of different modalities. The subsequent acquisition of image data may be performed automatically without operator intervention, or the prescribed subsequent acquisition sequence may be outputted by the system for execution upon command of an operator.
摘要翻译：本发明提供一种基于初始图像数据的分析在医疗诊断上下文中获取后续图像数据的技术。通过计算机辅助诊断算法处理初始图像数据，以确定附加图像数据采集是否合适。随后的采集过程可以在与其起始的图像数据相同的成像系统或不同的成像系统上执行。成像系统也可以是不同的模式。图像数据的后续采集可以在没有操作者干预的情况下自动执行，或者可以由系统输出规定的后续采集序列，以便在操作者的命令下执行。

5. 发明授权

US08137282B2 Method and system for determining a period of interest using multiple inputs 有权
标题翻译：使用多个输入确定兴趣期的方法和系统
公开(公告)号：US08137282B2
公开(公告)日：2012-03-20
申请号：US12099684
申请日：2008-04-08
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/02
CPC分类号： A61B6/5217 , A61B5/0037 , A61B5/04011 , A61B5/0402 , A61B5/0535 , A61B5/055 , A61B5/1107 , A61B5/7289 , A61B5/7292 , A61B6/03 , A61B6/527 , A61B6/541
摘要： One or more techniques are provided for identifying a period of minimal motion for an organ of interest, such as the heart or lungs. Motion data is acquired for the organ of interest and for one or more proximate organs using sensor-based and/or image-based techniques. The sensor-based techniques may include electrical and non-electrical techniques. The image-based techniques may include both pre-acquisition and acquisition image data. The motion data for the organ of interest and proximate organs may be used to generate a set of multi-input motion data that may be processed to identify desired periods, such as periods of minimal motion, within the overall motion of the organ of interest.
摘要翻译：提供一种或多种技术用于识别感兴趣的器官（例如心脏或肺）的最小运动周期。对于感兴趣的器官和使用基于传感器和/或基于图像的技术的一个或多个近端器官获取运动数据。基于传感器的技术可以包括电气和非电气技术。基于图像的技术可以包括预采集和采集图像数据。可以使用感兴趣的器官和邻近器官的运动数据来产生一组多输入运动数据，该组输入运动数据可被处理以识别期望的周期，例如感兴趣的器官的整体运动内的最小运动周期。

6. 发明授权

US07756565B2 Method and system for composite gating using multiple inputs 有权
标题翻译：多输入复合门控方法与系统
公开(公告)号：US07756565B2
公开(公告)日：2010-07-13
申请号：US10723857
申请日：2003-11-26
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/05
CPC分类号： A61B6/541 , A61B5/0037 , A61B5/7285 , A61B5/7289 , A61B5/7292 , A61B6/503 , G01R33/5673
摘要： One or more techniques are provided for determining the overall motion of an organ of interest relative to a viewer or imager. Motion data is acquired for the organ of interest and/or for one or more proximate organs using sensor-based and/or image data-based techniques. The sensor-based techniques may include electrical and non-electrical techniques. The image data-based techniques may include both pre-acquisition and acquisition image data. The motion data for the organ of interest and proximate organs may be used to determine one or more quiescent periods corresponding to intervals of minimal motion for the organ of interest and the proximate organs. The one or more quiescent periods may be used to determine one or more gating points that may be used prospectively, i.e., during image acquisition, and retrospectively, i.e., after image acquisition. In addition, the one or more quiescent periods may be used to determine one or more motion compensation factors that may be used during processing and reconstruction of the acquired image data. The gating points and motion compensation factors may be used, separately or together, to reduce motion-related artifacts in the reconstructed images.
摘要翻译：提供了一种或多种技术来确定感兴趣的器官相对于观看者或成像器的整体运动。使用基于传感器和/或图像数据的技术为感兴趣的器官和/或对于一个或多个近端器官获取运动数据。基于传感器的技术可以包括电气和非电气技术。基于图像数据的技术可以包括预采集和采集图像数据。感兴趣的器官和邻近器官的运动数据可用于确定对应于感兴趣器官和最近器官的最小运动的间隔的一个或多个静止期。可以使用一个或多个静止周期来确定可以预期使用的即一个或多个选通点，即，在图像采集期间，以及追溯地，即在图像采集之后。此外，一个或多个静止周期可以用于确定在所获取的图像数据的处理和重建期间可以使用的一个或多个运动补偿因子。门控点和运动补偿因子可以单独地或一起使用以减少重建图像中的运动相关假象。

7. 发明授权

US07389136B2 Method and system using a non-electrical sensor for gating 有权
标题翻译：使用非电气传感器进行门控的方法和系统
公开(公告)号：US07389136B2
公开(公告)日：2008-06-17
申请号：US10065960
申请日：2002-12-04
申请人： Gopal B. Avinash , Prathyusha K. Salla , Cherik Bulkes , TinSu Pan , Bernice E. Hoppel , Scott Thomas Mansell
发明人： Gopal B. Avinash , Prathyusha K. Salla , Cherik Bulkes , TinSu Pan , Bernice E. Hoppel , Scott Thomas Mansell
IPC分类号： A61B5/05
CPC分类号： A61B8/543 , A61B5/055 , A61B5/1102 , A61B5/113 , A61B5/7239 , A61B5/7285 , A61B5/7292 , A61B6/541 , A61B8/00 , A61B2562/0219
摘要： A method and system of gating for a medical imaging system includes utilizing a non-electrical sensor to acquire information for gating. A sensor assembly usable in the method and system of gating may include a non-electrical sensor coupled to one side of a patient-sensor interface, the other side adapted for securing to a patient.
摘要翻译：用于医学成像系统的门控的方法和系统包括利用非电传感器来获取门控信息。可用于门控方法和系统的传感器组件可以包括耦合到患者 - 传感器接口的一侧的非电传感器，另一侧适于固定在患者身上。

8. 发明授权

US08285359B2 Method and system for retrospective gating using multiple inputs 有权
标题翻译：使用多个输入回溯门控的方法和系统
公开(公告)号：US08285359B2
公开(公告)日：2012-10-09
申请号：US10723894
申请日：2003-11-26
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/055
CPC分类号： A61B6/541 , A61B5/0037 , A61B5/7289 , A61B5/7292 , A61B6/503 , A61B6/5288 , A61B8/0883 , A61B8/5284
摘要： One or more techniques are provided for determining the overall motion of an organ of interest relative to a viewer or imager. Motion data is acquired for the organ of interest and/or for one or more proximate organs using sensor-based and/or image data-based techniques. The sensor-based techniques may include electrical and non-electrical techniques. The image data-based techniques may include both pre-acquisition and acquisition image data. The motion data for the organ of interest and proximate organs may be used to determine one or more quiescent periods corresponding to intervals of minimal motion for the organ of interest and the proximate organs, which may be used to determine one or more gating points that may be used retrospectively, as well as one or more motion compensation factors that may be used to reduce motion-related artifacts during processing and reconstruction of the acquired image data.
摘要翻译：提供了一种或多种技术来确定感兴趣的器官相对于观看者或成像器的整体运动。使用基于传感器和/或图像数据的技术为感兴趣的器官和/或对于一个或多个近端器官获取运动数据。基于传感器的技术可以包括电气和非电气技术。基于图像数据的技术可以包括预采集和采集图像数据。可以使用感兴趣的器官和邻近器官的运动数据来确定对应于感兴趣的器官和邻近器官的最小运动的间隔的一个或多个静止期，其可以用于确定一个或多个选通点追溯使用，以及可以用于在所获取的图像数据的处理和重构期间减少运动相关假象的一个或多个运动补偿因子。

9. 发明授权

US07367953B2 Method and system for determining a period of interest using multiple inputs 失效
标题翻译：使用多个输入确定兴趣期的方法和系统
公开(公告)号：US07367953B2
公开(公告)日：2008-05-06
申请号：US10723858
申请日：2003-11-26
申请人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
发明人： Prathyusha K. Salla , Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/02
CPC分类号： A61B6/5217 , A61B5/0037 , A61B5/04011 , A61B5/0402 , A61B5/0535 , A61B5/055 , A61B5/1107 , A61B5/7289 , A61B5/7292 , A61B6/03 , A61B6/527 , A61B6/541
摘要： One or more techniques are provided for identifying a period of minimal motion for an organ of interest, such as the heart or lungs. Motion data is acquired for the organ of interest and for one or more proximate organs using sensor-based and/or image-based techniques. The sensor-based techniques may include electrical and non-electrical techniques. The image-based techniques may include both pre-acquisition and acquisition image data. The motion data for the organ of interest and proximate organs may be used to generate a set of multi-input motion data that may be processed to identify desired periods, such as periods of minimal motion, within the overall motion of the organ of interest.
摘要翻译：提供一种或多种技术用于识别感兴趣的器官（例如心脏或肺）的最小运动周期。对于感兴趣的器官和使用基于传感器和/或基于图像的技术的一个或多个近端器官获取运动数据。基于传感器的技术可以包括电气和非电气技术。基于图像的技术可以包括预采集和采集图像数据。可以使用感兴趣的器官和邻近器官的运动数据来产生一组多输入运动数据，该组输入运动数据可被处理以识别期望的周期，例如感兴趣的器官的整体运动内的最小运动周期。

10. 发明授权

US06942621B2 Method and apparatus for detecting weak physiological signals 失效
标题翻译：检测弱生理信号的方法和装置
公开(公告)号：US06942621B2
公开(公告)日：2005-09-13
申请号：US10192995
申请日：2002-07-11
申请人： Gopal B. Avinash , Cherik Bulkes
发明人： Gopal B. Avinash , Cherik Bulkes
IPC分类号： A61B5/0245 , A61B5/024 , A61B5/11 , A61B5/02
CPC分类号： A61B5/4362 , A61B5/02411 , A61B2562/0247 , A61B2562/043
摘要： A method and apparatus are provided for measuring a weak physiological signal in the presence of stronger signals. The method and apparatus utilize motion sensing devices placed on or about the patient to obtain a motion data set from each motion sensing device describing the aggregate detected motion. The data sets are synchronized and then used to solve a set of simultaneous equations which allows for the separation of the various motion components which may include such components of interest as fetal heart motion.
摘要翻译：提供了一种用于在存在较强信号的情况下测量弱生理信号的方法和装置。该方法和装置利用放置在患者身上或周围的运动感测装置，从每个运动检测装置获得描述聚合检测到的运动的运动数据集。数据集被同步，然后用于求解一组联立方程，其允许分离各种运动分量，其可以包括诸如胎儿心脏运动的感兴趣的组分。

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