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1. 发明授权

US06438418B1 Method and apparatus for reduction of pain from electric shock therapies 有权
标题翻译：减轻电击治疗疼痛的方法和装置
公开(公告)号：US06438418B1
公开(公告)日：2002-08-20
申请号：US09568237
申请日：2000-05-05
申请人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
发明人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
IPC分类号： A61N1362
CPC分类号： A61N1/395 , A61N1/36021 , A61N1/36071 , A61N1/39 , A61N1/3906 , A61N1/3956
摘要： A method and apparatus for pretreating a patient prior to a therapeutic painful stimulus, comprising the application of pain inhibiting stimuli to a patient prior to an application of the therapeutic painful stimulus. Applying pain inhibiting stimuli comprises the steps of sensing a need for the therapeutic painful stimulus, preparing to deliver the pain inhibiting stimuli to the patient prior to applying the therapeutic painful stimulus, and delivering the pain inhibiting stimuli to the patient prior to applying the therapeutic painful stimulus. The method and apparatus are embodied in modern, fully automatic, fully implantable, single or dual chamber atrial or ventricular cardioverter-defibrillators. The pain inhibiting prepulse method is intended primarily for use in conscious patients but may also be used in sleeping patients.
摘要翻译：一种用于在治疗性疼痛刺激之前预处理患者的方法和装置，包括在施用治疗性疼痛刺激之前向患者施用疼痛抑制刺激物。应用疼痛抑制刺激包括以下步骤：感觉需要治疗性疼痛刺激，准备在施用治疗性疼痛刺激之前将疼痛抑制刺激递送给患者，以及在施用治疗性疼痛之前将疼痛抑制刺激递送给患者刺激。该方法和装置体现在现代，全自动，完全可植入，单室或双室心房或心室心律转复除颤器中。疼痛抑制前脉冲法主要用于有意识的患者，但也可用于睡眠患者。

2. 发明授权

US6091989A Method and apparatus for reduction of pain from electric shock therapies 有权
标题翻译：减轻电击治疗疼痛的方法和装置
公开(公告)号：US6091989A
公开(公告)日：2000-07-18
申请号：US152382
申请日：1998-09-14
申请人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
发明人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
IPC分类号： A61N1/34 , A61N1/39
CPC分类号： A61N1/395 , A61N1/36021 , A61N1/39 , A61N1/3906 , A61N1/3956 , A61N1/36071
摘要： A method and apparatus for pretreating a patient prior to a therapeutic painful stimulus, comprising the application of pain inhibiting stimuli to a patient prior to an application of the therapeutic painful stimulus. Applying pain inhibiting stimuli comprises the steps of sensing a need for the therapeutic painful stimulus, preparing to deliver the pain inhibiting stimuli to the patient prior to applying the therapeutic painful stimulus, and delivering the pain inhibiting stimuli to the patient prior to applying the therapeutic painful stimulus. The method and apparatus are embodied in modem, fully automatic, fully implantable, single or dual chamber atrial or ventricular cardioverter-defibrillators. The pain inhibiting prepulse method is intended primarily for use in conscious patients but may also be used in sleeping patients.
摘要翻译：一种用于在治疗性疼痛刺激之前预处理患者的方法和装置，包括在施用治疗性疼痛刺激之前向患者施用疼痛抑制刺激物。应用疼痛抑制刺激包括以下步骤：感觉需要治疗性疼痛刺激，准备在施用治疗性疼痛刺激之前将疼痛抑制刺激递送给患者，以及在施用治疗性疼痛之前将疼痛抑制刺激递送给患者刺激。该方法和装置体现在调制解调器，全自动，完全可植入，单室或双室心室或心室心律转复除颤器中。疼痛抑制前脉冲法主要用于有意识的患者，但也可用于睡眠患者。

3. 发明授权

US06711442B1 Method and apparatus for reduction of pain from electric stimulation therapies 有权
标题翻译：减轻电刺激疗法疼痛的方法和装置
公开(公告)号：US06711442B1
公开(公告)日：2004-03-23
申请号：US09288209
申请日：1999-04-08
申请人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
发明人： Charles D. Swerdlow , Neal R. Swerdlow , James E. Brewer
IPC分类号： A61N134
CPC分类号： A61N1/395 , A61N1/36021 , A61N1/36071 , A61N1/39 , A61N1/3906 , A61N1/3956
摘要： A method and apparatus that pretreat a patient prior to each therapeutic painful stimulus in a series of therapeutic painful stimuli, comprising the application of pain inhibiting stimuli to the patient prior to the application of each therapeutic painful stimulus in the series. Applying pain inhibiting stimuli comprises the steps of sensing a need for a next therapeutic painful stimulus in a series, preparing to deliver the pain inhibiting stimuli to the patient prior to applying the next therapeutic painful stimulus, and delivering the pain inhibiting stimuli to the patient prior to applying the next therapeutic painful stimulus. The method and apparatus are embodied in modern, noninvasive, transcutaneous or transesophageal pacing devices, either as stand-alone cardiac pacemakers, combination pacemaker-ECG monitors, or combination pacemaker-monitor-defibrillators. The pain inhibiting prepulse method is intended primarily for use in conscious patients but may also be used in sleeping patients.
摘要翻译：一种在一系列治疗性疼痛刺激中的每种治疗性疼痛刺激之前对患者进行预处理的方法和装置，包括在施用所述系列中的每种治疗性疼痛刺激之前向患者施加疼痛抑制性刺激。应用疼痛抑制刺激包括以下步骤：感测需要下一次治疗性疼痛刺激的一系列，准备在施用下一个治疗性疼痛刺激之前将疼痛抑制刺激递送给患者，并将疼痛抑制刺激递送给患者应用下一个治疗性的痛苦刺激。该方法和装置体现在现代的，无创的，经皮的或经食道的起搏装置中，作为独立的心脏起搏器，组合的起搏器ECG监测器或组合的起搏器监测器 - 除颤器。疼痛抑制前脉冲法主要用于有意识的患者，但也可用于睡眠患者。

4. 发明授权

US5902323A Method and apparatus for external defibrillation using a device having a low capacitance and small time constant 失效
标题翻译：使用具有低电容和小时间常数的器件进行外部除颤的方法和装置
公开(公告)号：US5902323A
公开(公告)日：1999-05-11
申请号：US832710
申请日：1997-04-11
申请人： James E. Brewer , Charles D. Swerdlow
发明人： James E. Brewer , Charles D. Swerdlow
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61N1/3906 , A61N1/3912
摘要： A method and apparatus for delivering a truncated damped sinusoidal external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes is provided. The external defibrillator is utilized for applying a damped sinusoidal waveform having a first waveform phase and a second waveform phase to a pair of electrodes. The external defibrillator has a first capacitive component, a first inductive component, a first truncating switch, and waveform control circuitry. The waveform control circuitry of the defibrillator controls the first and second truncating switches such that the duration of the second phase waveform delivered by the second charge storage component is greater than the duration of the first phase waveform delivered by the first charge storage component.
摘要翻译：提供截断的阻尼正弦外部除颤波形的方法和装置，该波形在通过位于患者躯体上的多个电极施加时将在患者的心脏细胞膜中产生期望的响应。外部除颤器用于向一对电极施加具有第一波形相位和第二波形相位的阻尼正弦波形。外部除颤器具有第一电容分量，第一电感分量，第一截断开关和波形控制电路。除颤器的波形控制电路控制第一和第二截断开关，使得由第二电荷存储部件传送的第二相位波形的持续时间大于由第一电荷存储部件传送的第一相位波形的持续时间。

5. 发明授权

US6134479A Electrode triad for external defibrillation 有权
标题翻译：用于外部除颤的电极三元组
公开(公告)号：US6134479A
公开(公告)日：2000-10-17
申请号：US243579
申请日：1999-02-03
申请人： James E. Brewer , Charles D. Swerdlow , Kenneth F. Olson
发明人： James E. Brewer , Charles D. Swerdlow , Kenneth F. Olson
IPC分类号： A61N1/04
CPC分类号： A61N1/046 , A61N1/0492
摘要： An energy delivery system for use with an automatic external defibrillator (AED), the AED having a case containing a plurality of AED components, a battery electrically coupled to a control system, the control system communicatively coupled to a charge system, the charge system for generating a stored quantity of energy responsive to a communication from the control system, the control system selectively commanding a discharge of the stored energy to an electrical connector, the energy delivery system includes three electrodes, each electrode for making electrical contact with a skin surface of a patient, each electrode being in electrical contact with the electrical connector for communicating the stored energy to the patient. A method of defibrillating the heart of a patient using an AED, the AED having electrical energy discharge circuitry for generating a defibrillating energy discharge to affect the heart of the patient, the heart being in a state of fibrillation, includes the steps of placing three electrodes on the person of a patient to define a desired electrical path and discharging electrical energy across the electrical path.
摘要翻译：一种用于与自动外部除颤器（AED）一起使用的能量输送系统，所述AED具有包含多个AED部件的壳体，电耦合到控制系统的电池，所述控制系统通信地耦合到充电系统，所述充电系统用于响应于来自控制系统的通信产生存储量的能量，控制系统选择性地将存储的能量排放到电连接器，能量传递系统包括三个电极，每个电极用于与皮肤表面电接触患者，每个电极与电连接器电接触，以将存储的能量传递给患者。一种使用AED除颤患者心脏的方法，所述AED具有用于产生除颤能量放电以影响患者心脏的电能放电电路的心脏处于原纤维化状态的电能放电电路包括以下步骤：放置三个电极在患者身上定义所需的电气路径并在电路径上排出电能。

6. 发明授权

US08483822B1 Adaptive medium voltage therapy for cardiac arrhythmias 有权
标题翻译：心律失常的适应性中压治疗
公开(公告)号：US08483822B1
公开(公告)日：2013-07-09
申请号：US12830251
申请日：2010-07-02
申请人： Byron L. Gilman , Mark W. Kroll , James E. Brewer
发明人： Byron L. Gilman , Mark W. Kroll , James E. Brewer
IPC分类号： A61N1/00
CPC分类号： A61N1/3925 , A61N1/3605 , A61N1/362 , A61N1/3621 , A61N1/36564 , A61N1/39 , A61N1/3956 , A61N1/3968 , A61N1/3993
摘要： Aspects of the invention are directed to advanced monitoring and control of medium voltage therapy (MVT) in implantable and external devices. Apparatus and methods are disclosed that facilitate dynamic adjustment of MVT parameter values in response to new and changing circumstances such as the patient's condition before, during, and after administration of MVT. Administration of MVT is automatically and dynamically adjusted to achieve specific treatment or life-support objectives, such as prolongation of the body's ability to endure and respond to MVT, specifically addressing the type of arrhythmia or other pathologic state of the patient with targeted treatment, a tiered-intensity MVT treatment strategy, and supporting patients in non life-critical conditions where the heart may nevertheless benefit from a certain level of assistance.
摘要翻译：本发明的方面涉及可植入和外部设备中的中压治疗（MVT）的高级监视和控制。公开了用于响应于新的和变化的情况（例如在MVT管理之前，之中和之后的患者状况）MVT参数值的动态调整的装置和方法。自动动态地调整MVT的管理，以达到特定的治疗或生命维持目标，例如延长身体耐受和应对MVT的能力，具体针对靶向治疗患者的心律失常或其他病理状态，分层强度的MVT治疗策略，并支持非生命危险条件下的患者，心脏可能受益于一定程度的帮助。

7. 发明申请

US20120320907A1 Systems and Methods of Providing Multi-Homed Tandem Access 有权
标题翻译：提供多功能串联访问的系统和方法
公开(公告)号：US20120320907A1
公开(公告)日：2012-12-20
申请号：US13598710
申请日：2012-08-30
申请人： Scott D. Kell , James E. Brewer , Anthony J. Hiller
发明人： Scott D. Kell , James E. Brewer , Anthony J. Hiller
IPC分类号： H04L12/66
CPC分类号： H04M15/47 , H04M3/42238 , H04M3/42314 , H04M7/1285 , H04Q3/62
摘要： Systems and methods for providing multi-homed tandem access in a communication system are disclosed. The disclosure may include a private packet network backbone exchange (PPNBE) in connection with a set of access tandems and with a call destination such as an end-user or a communications service. A set of LRNs may be homed across the set of access tandems, with each of the set of LRNs mapped to one or more TNs corresponding to the call destination. An originating party may use any of the TNs to reach the call destination. A plurality of originating calls each including one of the TNs may be received at the PPNBE from any of the access tandems and routed to the call destination. Thus, the present disclosure provides greater call capacity than available access tandem architectures as well as optimizes a maximum number of call paths to a particular call destination.
摘要翻译：公开了一种在通信系统中提供多宿主串联接入的系统和方法。本公开可以包括与一组接入串联以及诸如终端用户或通信服务之类的呼叫目的地有关的私有分组网络骨干交换机（PPNBE）。一组LRN可以被归属在该组接入串联之间，其中每组LRN被映射到对应于呼叫目的地的一个或多个TN。发起方可以使用任何TN来到达呼叫目的地。可以在PPNBE处从任何一个接入串并接收多个发起呼叫，每个呼叫都包括TN中的一个，并且路由到呼叫目的地。因此，本公开提供比可用接入串联架构更大的呼叫容量，以及优化到特定呼叫目的地的呼叫路径的最大数量。

8. 发明授权

US07565194B2 ECG rhythm advisory method 有权
标题翻译：心电图节律咨询方法
公开(公告)号：US07565194B2
公开(公告)日：2009-07-21
申请号：US10844253
申请日：2004-05-12
申请人： Qing Tan , Gary A. Freeman , Frederick Geheb , James E. Brewer
发明人： Qing Tan , Gary A. Freeman , Frederick Geheb , James E. Brewer
IPC分类号： A61N1/39
CPC分类号： A61B5/04014 , A61B5/0402 , A61B5/046 , A61B5/0464 , A61B5/4839 , A61B5/7207 , A61B5/7257 , A61B5/726 , A61H31/005 , A61H2201/5015 , A61H2230/04 , A61N1/39 , A61N1/3925
摘要： A method of automatically determining which type of treatment is most appropriate for a cardiac arrest victim, the method comprising transforming one or more time domain electrocardiogram (ECG) signals into a frequency domain representation comprising a plurality of discrete frequency bands, combining the discrete frequency bands into a plurality of analysis bands, wherein there are fewer analysis bands than discrete frequency bands,determining the content of the analysis bands, and determining the type of treatment based on the content of the analysis bands.
摘要翻译：一种自动确定哪种类型的治疗最适合于心脏骤停受害者的方法，所述方法包括将一个或多个时域心电图（ECG）信号变换成包括多个离散频带的频域表示，组合离散频带分析成多个分析频带，其中分离频带比离散频带少，确定分析频带的内容，并根据分析频带的内容确定治疗类型。

9. 发明授权

US5899924A Single capacitor truncated damped sinusoidal defibrillation waveform 失效
标题翻译：单电容器截断阻尼正弦除颤波形
公开(公告)号：US5899924A
公开(公告)日：1999-05-04
申请号：US833935
申请日：1997-04-10
申请人： James E. Brewer , Gary B. Stendahl
发明人： James E. Brewer , Gary B. Stendahl
IPC分类号： A61N1/39
CPC分类号： A61N1/39 , A61N1/3906 , A61N1/3912 , A61N1/3925
摘要： A method and apparatus for delivering a truncated damped sinusoidal external defibrillation waveform which, when applied through a plurality of electrodes positioned on a patient's torso will produce a desired response in the patient's cardiac cell membranes is provided. The method includes the steps monitoring a patient-dependent electrical parameter and determining a duration based on the parameter determined. A first set of charge storage capacitors is then charged. A first truncating switch is then closed to discharge the first set of capacitors. Then, after the duration period that was calculated has expired the switch is opened to truncate the waveform. The computation of discharge duration is made as a function of the desired cardiac membrane response function, a patient model and a defibrillator circuit model.
摘要翻译：提供截断的阻尼正弦外部除颤波形的方法和装置，该波形在通过位于患者躯体上的多个电极施加时将在患者的心脏细胞膜中产生期望的响应。该方法包括监视与患者相关的电参数并基于确定的参数来确定持续时间的步骤。然后对第一组电荷存储电容器充电。然后关闭第一截断开关以对第一组电容器进行放电。然后，在计算的持续时间段到期后，开关打开以截断波形。放电持续时间的计算作为所需心脏膜响应函数，患者模型和除颤器电路模型的函数。

10. 发明授权

US5700281A Stage and state monitoring automated external defibrillator 失效
标题翻译：舞台和状态监测自动化外部除颤器
公开(公告)号：US5700281A
公开(公告)日：1997-12-23
申请号：US668117
申请日：1996-06-17
申请人： James E. Brewer , Kenneth F. Olson , John F. Stolte , Nora J. Utke , Gary B. Stendahl
发明人： James E. Brewer , Kenneth F. Olson , John F. Stolte , Nora J. Utke , Gary B. Stendahl
IPC分类号： A61N1/04 , A61N1/08 , A61N1/39
CPC分类号： A61N1/04 , A61N1/3931 , A61N2001/083
摘要： A circuit detectable arrangement of a plurality of medical electrodes is provided with each electrode having an electrically nonconductive backing layer, a layer of electrically conductive adhesive disposed on the backing layer and a lead wire extending therefrom and electrically connected with the conductive adhesive. More specifically, a first electrode is disposed on an electrically nonconductive liner, a second electrode is disposed on an electrically nonconductive liner, and an electrical connector is provided between the first and second electrodes for electrically completing a circuit connecting the lead wire of the first electrode to the lead wire of the second electrode. Preferably, the backing layers of the first and second electrodes each include a conductor portion, and the electrical connector is connected between the conductor portion of the backing layer of the first electrode and the conductor portion of the backing layer of the second electrode. The electrical connector preferably comprises a strip of flexible and electrically conductive material and may include a nonconductive tear resistant strip. Utilizing the electrode packaging above, the present invention monitors the state of the AED and the stage of a rescue. In particular, at least five stages of a rescue are monitored. These include: 1) rescue initiated; 2) preparing victim; 3) applying electrodes; 4) AED in use; and 5) rescue completed.
摘要翻译：提供了多个医疗电极的电路可检测布置，每个电极具有不导电背衬层，设置在背衬层上的导电粘合剂层和从其延伸并与导电粘合剂电连接的引线。更具体地，第一电极设置在非导电衬垫上，第二电极设置在非导电衬垫上，并且电连接器设置在第一和第二电极之间，用于电完成连接第一电极的引线的电路到第二电极的引线。优选地，第一和第二电极的背衬层各自包括导体部分，并且电连接器连接在第一电极的背衬层的导体部分和第二电极的背衬层的导体部分之间。电连接器优选地包括柔性和导电材料条，并且可以包括不导电的抗撕裂条带。利用上述电极封装，本发明监视AED的状态和救援的阶段。特别是对至少五个营救阶段进行监控。这些包括：1）救援启动; 2）准备受害人; 3）施加电极; 4）使用中的AED 和5）抢救完成。

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