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1. 发明授权

US07799563B2 Carrier fiber assembly for tissue structures 有权
标题翻译：用于组织结构的载体纤维组件
公开(公告)号：US07799563B2
公开(公告)日：2010-09-21
申请号：US10976952
申请日：2004-10-29
申请人： Charles A. Howland , Virginia Houston-Howland , Jennifer K. White
发明人： Charles A. Howland , Virginia Houston-Howland , Jennifer K. White
IPC分类号： A61F2/02
CPC分类号： A61L27/3691 , A61L27/3683 , A61L27/58 , Y10S623/915
摘要： Methods and structures are disclosed where carrier fiber is used to enable the assembly of two and three dimensional structures of autologous tissue. Tissue is harvested from the donor, integrated with a carrier fiber, and assembled into complex forms rapidly. The structures can be tailored to the requirements of a specific medical procedure. The tissue is kept live and viable during extracorporeal assembly and the finished structure is emplaced in the donor's body. The use of a carrier fiber leader for pre-threading integration and assembly machines facilitates machine set up, drawing of the tissue into the process, and rapid integration and assembly of the multi-dimensional structures. Assembly can include providing tissue and fiber leaders extending from the structure for attaching the structure in place. The carrier fiber either is bio-absorbed as new tissue forms, or forms a bio-compatible substructure for the patient's native tissue.
摘要翻译：公开了使用载体纤维来实现自体组织的二维和三维结构的组装的方法和结构。从供体收获组织，与载体纤维结合，并快速组装成复杂形式。结构可以根据具体医疗程序的要求进行调整。组织在体外组装过程中保持活力和活力，并将成品结构放置在供体的身体中。使用载体纤维引导器进行预穿线整合和组装机器，便于机器设置，将组织拉伸到工艺中，以及快速整合和组装多维结构。组装可以包括提供从结构延伸的组织和纤维束头，用于将结构附接到位。载体纤维作为新组织形成生物吸收，或形成用于患者天然组织的生物相容性子结构。

2. 发明授权

US09039756B2 Repositionable endoluminal support structure and its applications 有权
标题翻译：可重新定位的腔内支架结构及其应用
公开(公告)号：US09039756B2
公开(公告)日：2015-05-26
申请号：US13069037
申请日：2011-03-22
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/06 , A61F2/24 , A61F2/844
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2469 , A61F2/844 , A61F2210/0076 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004
摘要： An endoluminal support structure includes strut members interconnected by pivot joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
摘要翻译：腔内支撑结构包括通过枢转关节相互连接以形成一系列连接的剪刀机构的支柱构件。可以通过在一定范围的运动范围内调节剪刀接头来远程地致动结构来压缩或扩大其形状。特别地，支撑结构可以在体腔内重新定位或从内腔取回。可以使用支撑结构来引入和支撑体腔内的人造瓣膜。

3. 发明授权

US07331993B2 Involuted endovascular valve and method of construction 有权
标题翻译：血管内瓣膜及其构造方法
公开(公告)号：US07331993B2
公开(公告)日：2008-02-19
申请号：US10512005
申请日：2003-05-05
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/24 , B28B1/00
CPC分类号： A61F2/2415 , A61F2/2412 , A61F2/2418
摘要： A prosthetic tri-leaflet valve formed by involuting a portion of a tubular structure inside itself. The valve can be made by a method comprising providing a tubular segment in which three equidistant longitudinal incisions are made in one end of the tube creating three flaps which are involuted, i.e., folded, in toward the inside of the tube and the edges of the flaps secured to the inner wall of the tube to form leaflets. The tube can be formed of a single sheet of synthetic, organic or biological material and can be solid, woven, braided or the like. A braided configuration permits the valve to be annularly compressed and delivered to the site using a minimally invasive delivery mechanism, then expanded at the implantation site.
摘要翻译：一种假体三叶瓣，其通过将其内部的管状结构的一部分伸出而形成。该阀可以通过一种方法制成，该方法包括提供管状部分，其中在管的一端形成三个等距的纵向切口，形成三个折片，这三个折片朝向管的内部渐开，即折叠，固定到管的内壁的瓣片形成传单。管可以由合成的，有机的或生物材料的一片形成，并且可以是固体，编织，编织等。编织构造允许阀被环形压缩并使用微创输送机构输送到现场，然后在植入部位扩展。

4. 发明授权

US09005272B2 Repositionable endoluminal support structure and its applications 有权
公开(公告)号：US09005272B2
公开(公告)日：2015-04-14
申请号：US13111855
申请日：2011-05-19
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/06 , A61F2/24 , A61F2/82 , A61F2/844
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endoluminal support structure includes strut members interconnected by pivot joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.

5. 发明申请

US20080133004A1 INVOLUTED CYLINDER VALVE 审中-公开
标题翻译：相关气缸
公开(公告)号：US20080133004A1
公开(公告)日：2008-06-05
申请号：US11945855
申请日：2007-11-27
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/24
CPC分类号： A61F2/2415 , A61F2/2412 , A61F2/2418
摘要： A prosthetic tri-leaflet valve formed by involuting a portion of a tubular structure inside itself. The valve can be made by a method comprising providing a tubular segment in which three equidistant longitudinal incisions are made in one end of the tube creating three flaps which are involuted, i.e., folded, in toward the inside of the tube and the edges of the flaps secured to the inner wall of the tube to form leaflets. The tube can be formed of a single sheet of synthetic, organic or biological material and can be solid, woven, braided or the like. A braided configuration permits the valve to be annularly compressed and delivered to the site using a minimally invasive delivery mechanism, then expanded at the implantation site.
摘要翻译：一种假体三叶瓣，其通过将其内部的管状结构的一部分伸出而形成。该阀可以通过一种方法制成，该方法包括提供管状部分，其中在管的一端形成三个等距的纵向切口，形成三个折片，这三个折片朝向管的内部渐开，即折叠，固定到管的内壁的瓣片形成传单。管可以由合成的，有机的或生物材料的一片形成，并且可以是固体，编织，编织等。编织构造允许阀被环形压缩并使用微创输送机构输送到现场，然后在植入部位扩展。

6. 发明授权

US09364323B2 Repositionable endoluminal support structure and its applications 有权
标题翻译：可重新定位的腔内支架结构及其应用
公开(公告)号：US09364323B2
公开(公告)日：2016-06-14
申请号：US13113890
申请日：2011-05-23
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/24 , A61F2/82 , A61F2/94 , A61F2/844
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
摘要翻译：腔内支撑结构包括通过旋转接头互连以形成一系列连接的剪刀机构的支柱构件。可以通过在一定范围的运动范围内调节剪刀接头来远程地致动结构来压缩或扩大其形状。特别地，支撑结构可以在体腔内重新定位或从内腔取回。可以使用支撑结构来引入和支撑体腔内的人造瓣膜。

7. 发明授权

US09259314B2 Repositionable endoluminal support structure and its applications 有权
公开(公告)号：US09259314B2
公开(公告)日：2016-02-16
申请号：US13158232
申请日：2011-06-10
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/24 , A61F2/844 , A61F2/82
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.

8. 发明授权

US08852261B2 Repositionable endoluminal support structure and its applications 有权
标题翻译：可重新定位的腔内支架结构及其应用
公开(公告)号：US08852261B2
公开(公告)日：2014-10-07
申请号：US13113887
申请日：2011-05-23
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
摘要翻译：腔内支撑结构包括通过旋转接头互连以形成一系列连接的剪刀机构的支柱构件。可以通过在一定范围的运动范围内调节剪刀接头来远程地致动结构来压缩或扩大其形状。特别地，支撑结构可以在体腔内重新定位或从内腔取回。可以使用支撑结构来引入和支撑体腔内的人造瓣膜。

9. 发明授权

US08685080B2 Repositionable endoluminal support structure and its applications 有权
标题翻译：可重新定位的腔内支架结构及其应用
公开(公告)号：US08685080B2
公开(公告)日：2014-04-01
申请号：US13055441
申请日：2009-07-21
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endo luminal support structure (10) includes strut members (11) interconnected by swivel joints (15) to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve (100) within a body lumen.
摘要翻译：内腔管支撑结构（10）包括通过旋转接头（15）互连的支柱构件（11），以形成一系列连接的剪刀机构。可以通过在一定范围的运动范围内调节剪刀接头来远程地致动结构来压缩或扩大其形状。特别地，支撑结构可以在体腔内重新定位或从内腔取回。可以使用支撑结构来引入和支撑体腔内的人造瓣膜（100）。

10. 发明授权

US08226707B2 Repositionable endoluminal support structure and its applications 有权
标题翻译：可重新定位的腔内支架结构及其应用
公开(公告)号：US08226707B2
公开(公告)日：2012-07-24
申请号：US12761295
申请日：2010-04-15
申请人： Jennifer K. White
发明人： Jennifer K. White
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2469 , A61F2/82 , A61F2/844 , A61F2/94 , A61F2210/0076 , A61F2220/0041 , A61F2220/0075 , A61F2230/0054 , A61F2230/0091 , A61F2250/0004 , A61F2250/001 , Y10T29/49826
摘要： An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.
摘要翻译：腔内支撑结构包括通过旋转接头互连以形成一系列连接的剪刀机构的支柱构件。可以通过在一定范围的运动范围内调节剪刀接头来远程地致动结构来压缩或扩大其形状。特别地，支撑结构可以在体腔内重新定位或从内腔取回。可以使用支撑结构来引入和支撑体腔内的人造瓣膜。

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