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1. 发明申请

US20100324153A1 ANIONIC ISOSORBIDE DERIVATIVES AND THEIR USE 有权
标题翻译：阴离子异硫氰酸酯衍生物及其用途
公开(公告)号：US20100324153A1
公开(公告)日：2010-12-23
申请号：US12818346
申请日：2010-06-18
申请人： Ansgar Behler , Catherine Breffa , Hans-Christian Raths , Thorsten Lohl
发明人： Ansgar Behler , Catherine Breffa , Hans-Christian Raths , Thorsten Lohl
IPC分类号： A61K8/49 , C07D493/04 , C11D1/26
CPC分类号： C07D493/04
摘要： Disclosed are isosorbide derivatives according to the following general formula wherein R represent a hydrogen atom, or an alkyl group with 6 to 22 C-atoms, or an acyl group, or a group X—SO3M, and M stands for a cation, a hydrogen atom or an alkali metal atom or an ammonium or an alkylammonium ion, and X represents an alkoxylated derivative (AO)n wherein AO represents a group C2H4O, or C3H6O, or any mixtures thereof, and the index n is zero or 1 to 20, and p represents a number between 1 and 10, preferably between 1 and 4, and the use thereof to prepare cleansers, detergents, personal care compositions, or cosmetic compositions.
摘要翻译：公开了根据以下通式的异山梨醇衍生物，其中R表示氢原子或具有6至22个碳原子的烷基或酰基或X-SO 3 M基团，M表示阳离子，氢原子或碱金属原子或铵或烷基铵离子，X表示烷氧基化衍生物（AO）n，其中AO表示基团C 2 H 4 O或C 3 H 6 O或其任何混合物，并且指数n为0或1至20， p表示1至10之间，优选1至4之间的数字，以及其用于制备清洁剂，洗涤剂，个人护理组合物或化妆品组合物的用途。

2. 发明授权

US08334318B2 Anionic isosorbide derivatives and their use (II) 有权
标题翻译：阴离子异山梨醇衍生物及其用途（二）
公开(公告)号：US08334318B2
公开(公告)日：2012-12-18
申请号：US12961070
申请日：2010-12-06
申请人： Catherine Breffa , Hans-Christian Raths , Ansgar Behler
发明人： Catherine Breffa , Hans-Christian Raths , Ansgar Behler
IPC分类号： A61K31/34 , C07D493/02
CPC分类号： C07D493/04 , C11D1/28
摘要： Disclosed are isosorbide derivatives of formula (I) wherein R and R′ independently represent an isosorbide moiety, a hydrogen atom, or an alkyl group having 6 to 22 carbon atoms, and A stands for hydrogen, an alkali metal, ammonium or alkylammonium, with the proviso that at least one of R and R′ is an isosorbide group. Also disclosed is the use of compounds (I) for the preparation of cleansers, detergents, personal care compositions, and cosmetic or pharmaceutical compositions.
摘要翻译：公开了式（I）的异山梨醇衍生物，其中R和R'独立地表示异山梨醇部分，氢原子或具有6至22个碳原子的烷基，A代表氢，碱金属，铵或烷基铵，与条件是R和R'中的至少一个是异山梨醇基。还公开了化合物（I）用于制备清洁剂，洗涤剂，个人护理组合物以及化妆品或药物组合物的用途。

3. 发明申请

US20110135583A1 Anionic Isosorbide Derivatives and Their Use (II) 有权
标题翻译：阴离子异山梨醇衍生物及其用途（二）
公开(公告)号：US20110135583A1
公开(公告)日：2011-06-09
申请号：US12961070
申请日：2010-12-06
申请人： Catherine Breffa , Hans-Christian Raths , Ansgar Behler
发明人： Catherine Breffa , Hans-Christian Raths , Ansgar Behler
IPC分类号： A61K8/49 , C07D493/04 , A61K47/22 , A61Q5/02 , A61Q19/10 , C11D17/00 , A61Q11/00 , C11D3/20 , C11D1/26
CPC分类号： C07D493/04 , C11D1/28
摘要： Disclosed are isosorbide derivatives of formula (I) wherein R and R′ independently represent an isosorbide moiety, a hydrogen atom, or an alkyl group having 6 to 22 carbon atoms, and A stands for hydrogen, an alkali metal, ammonium or alkylammonium, with the proviso that at least one of R and R′ is an isosorbide group. Also disclosed is the use of compounds (I) for the preparation of cleansers, detergents, personal care compositions, and cosmetic or pharmaceutical compositions.
摘要翻译：公开了式（I）的异山梨醇衍生物，其中R和R'独立地表示异山梨醇部分，氢原子或具有6至22个碳原子的烷基，A代表氢，碱金属，铵或烷基铵，与条件是R和R'中的至少一个是异山梨醇基。还公开了化合物（I）用于制备清洁剂，洗涤剂，个人护理组合物以及化妆品或药物组合物的用途。

4. 发明申请

US20140356296A1 Use Of Isosorbide Derivatives For Producing Cosmetic Preparations 审中-公开
标题翻译：用于生产化妆品制剂的异山梨醇衍生物
公开(公告)号：US20140356296A1
公开(公告)日：2014-12-04
申请号：US14345736
申请日：2012-09-07
申请人： Claudia Stoer , Markus Dierker , Claus Nieendick , Werner Seipel , Ansgar Behler , Daniela Prinz , Catherine Breffa , Markus Weissenegger , Hans-Christian Raths
发明人： Claudia Stoer , Markus Dierker , Claus Nieendick , Werner Seipel , Ansgar Behler , Daniela Prinz , Catherine Breffa , Markus Weissenegger , Hans-Christian Raths
IPC分类号： A61K8/49 , A61Q19/00 , A61Q5/00 , C07D493/04
CPC分类号： A61K8/4973 , A61K2800/10 , A61K2800/26 , A61K2800/48 , A61Q5/00 , A61Q19/00 , A61Q19/10 , C07D493/04
摘要： Described are isosorbide derivatives according to general formula wherein R and R′, independently of one another, are: (i) hydrogen atom, or (ii) radical COR″, wherein R″ is linear or branched, saturated or unsaturated alkyl radical having 5 to 23 carbon atoms, or (iii) linear or branched, saturated or unsaturated alkyl radical having 6 to 22 carbon atoms, or (iv) radical CH2—CHOH—R′″, wherein R′″ is linear or branched alkyl radical having 6 to 22 carbon atoms, or (v) radical (CH2—CH2O)n—H and/or (CH2—CH(CH3)—O)m—H, wherein n and m, independently of one another, are an integer or fraction from 1 to 10, or (vi) for radical SO3OX, wherein X represents a sodium or ammonium ion, with the proviso that at most one of the radicals R and R′ is a hydrogen atom. The isosorbide derivatives are useful as components of cosmetic compositions.
摘要翻译：描述根据通式的异山梨醇衍生物，其中R和R'彼此独立地是：（i）氢原子或（ii）自由基COR“，其中R”是具有5或5的直链或支链，饱和或不饱和的烷基至（23）个碳原子，或（iii）具有6至22个碳原子的直链或支链，饱和或不饱和的烷基，或（iv）CH 2 -CHOH-R'基团，其中R'“是具有6个碳原子的直链或支链烷基至（22）个碳原子，或（v）自由基（CH 2 -CH 2 O）n -H和/或（CH 2 -CH（CH 3）-O）m -H，其中n和m彼此独立地是整数或分数 1至10，或（vi）对于SO 3 X 4基团，其中X代表钠或铵离子，条件是R和R'中至多有一个是氢原子。异山梨醇衍生物可用作化妆品组合物的组分。

5. 发明授权

US08546446B2 Anionic isosorbide derivatives and their use 有权
标题翻译：阴离子异山梨醇衍生物及其用途
公开(公告)号：US08546446B2
公开(公告)日：2013-10-01
申请号：US12818346
申请日：2010-06-18
申请人： Ansgar Behler , Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
发明人： Ansgar Behler , Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
IPC分类号： A61K31/34
CPC分类号： C07D493/04
摘要： Disclosed are isosorbide derivatives according to the following general formula wherein R represent a hydrogen atom, or an alkyl group with 6 to 22 C-atoms, or an acyl group, or a group X—SO3M, and M stands for a cation, a hydrogen atom or an alkali metal atom or an ammonium or an alkylammonium ion, and X represents an alkoxylated derivative (AO)n wherein AO represents a group C2H4O, or C3H6O, or any mixtures thereof, and the index n is zero or 1 to 20, and p represents a number between 1 and 10, preferably between 1 and 4, and the use thereof to prepare cleansers, detergents, personal care compositions, or cosmetic compositions.
摘要翻译：公开了根据以下通式的异山梨醇衍生物，其中R表示氢原子或具有6至22个碳原子的烷基或酰基或X-SO 3 M基团，M表示阳离子，氢原子或碱金属原子或铵或烷基铵离子，X表示烷氧基化衍生物（AO）n，其中AO表示基团C 2 H 4 O或C 3 H 6 O或其任何混合物，并且指数n为0或1至20， p表示1至10之间，优选1至4之间的数字，以及其用于制备清洁剂，洗涤剂，个人护理组合物或化妆品组合物的用途。

6. 发明申请

US20110237809A1 Isosorbide Derivatives 有权
标题翻译：异山梨醇衍生物
公开(公告)号：US20110237809A1
公开(公告)日：2011-09-29
申请号：US13123666
申请日：2009-09-30
申请人： Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
发明人： Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
IPC分类号： C07D493/04
CPC分类号： C07D493/04
摘要： Disclosed are derivatives of isosorbide having formula (1) wherein R′ and R″ represent hydrogen or a polymeric ether moiety (CH2—CHR1—O)x—H, where R1 represents hydrogen, or an alkyl or alkenyl moiety having 1 to 33 carbon atoms, which is saturated or unsaturated, branched or linear. This polymeric ether moiety can be a homopolymer or a copolymer, with x being the total degree of polymerization (DP). Preferred is a block copolymer composed of monomer A (DP=a), preferably ethylene oxide or propylene oxide, and monomer B (DP=b), preferably a saturated or unsaturated, branched or linear alkyl or alkenyl moiety having 1 to 33 carbon atoms, where x=a+b. x is a number from 0 to 50, with the proviso that R′ and R″ are not both hydrogen. The isosorbide derivatives are useful as components of detergent, cleanser, cosmetic and agricultural compositions.
摘要翻译：公开了具有式（1）的异山梨醇的衍生物，其中R'和R“表示氢或聚合醚部分（CH 2 -CHR-O）x -H，其中R 1表示氢，或具有1至33个碳原子的烷基或烯基部分原子，其是饱和或不饱和的，支链或直链的。该聚合醚部分可以是均聚物或共聚物，其中x是总聚合度（DP）。优选由单体A（DP = a），优选环氧乙烷或环氧丙烷和单体B（DP = b）组成的嵌段共聚物，优选具有1至33个碳原子的饱和或不饱和的支链或直链烷基或烯基部分，其中x = a + b。 x是0至50的数，条件是R'和R“不是氢。异山梨醇衍生物可用作洗涤剂，清洁剂，化妆品和农业组合物的组分。

7. 发明授权

US08575372B2 Isosorbide derivatives 有权
标题翻译：异山梨醇衍生物
公开(公告)号：US08575372B2
公开(公告)日：2013-11-05
申请号：US13123666
申请日：2009-09-30
申请人： Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
发明人： Catherine Breffa , Hans-Christian Raths , Thorsten Löhl
IPC分类号： C07D493/00
CPC分类号： C07D493/04
摘要： Disclosed are derivatives of isosorbide having formula (I) wherein R′ and R″ represent hydrogen or a polymeric ether moiety (CH2—CHR1—O)x—H, where R1 represents hydrogen, or an alkyl or alkenyl moiety having 1 to 33 carbon atoms, which is saturated or unsaturated, branched or linear. This polymeric ether moiety can be a homopolymer or a copolymer, with x being the total degree of polymerization (DP). Preferred is a block copolymer composed of monomer A (DP=a), preferably ethylene oxide or propylene oxide, and monomer B (DP=b), preferably a saturated or unsaturated, branched or linear alkyl or alkenyl moiety having 1 to 33 carbon atoms, where x=a+b. x is a number from 0 to 50, with the proviso that R′ and R″ are not both hydrogen. The isosorbide derivatives are useful as components of detergent, cleanser, cosmetic and agricultural compositions.
摘要翻译：公开了具有式（I）的式（I）的衍生物，其中R'和R“表示氢或聚合醚部分（CH2-CHR1-O）xH，其中R1表示氢，或具有1至33个碳原子的烷基或烯基部分，其为饱和或不饱和的，支链或直链的。该聚合醚部分可以是均聚物或共聚物，其中x是总聚合度（DP）。优选由单体A（DP = a），优选环氧乙烷或环氧丙烷和单体B（DP = b）组成的嵌段共聚物，优选具有1至33个碳原子的饱和或不饱和的支链或直链烷基或烯基部分，其中x = a + b。 x是0至50的数，条件是R'和R“不同时为氢。异山梨醇衍生物可用作洗涤剂，清洁剂，化妆品和农业组合物的组分。

8. 发明申请

US20110059884A1 USE OF ISOSORBIDE ETHERS IN DETERGENTS AND CLEANERS 有权
标题翻译：异烟肼在洗涤剂和清洁剂中的使用
公开(公告)号：US20110059884A1
公开(公告)日：2011-03-10
申请号：US12875600
申请日：2010-09-03
申请人： Catherine Breffa , Burkhard Beckedahl , Markus Dierker , Ansgar Behler , Thorsten Lohl
发明人： Catherine Breffa , Burkhard Beckedahl , Markus Dierker , Ansgar Behler , Thorsten Lohl
IPC分类号： C11D3/20
CPC分类号： C11D3/2096 , A61K8/4973 , A61K2800/48 , A61K2800/52 , A61Q19/10 , C11D1/662
摘要： The application pertains to the use of isosorbide ethers according to general formula (I) wherein R′ and R″ independently from each other represent a hydrogen atom or a alkyl- or unsaturated alkenyl moiety for the preparation of detergents and cleaners. Preferably R′ and/or R″ are linear or branched, saturated or unsaturated alkyl or alkenyl moiety containing 1 to 33 C-Atoms. A second, independent embodiment pertains to the use of these compounds as thickener for aqueous/surfactant compositions.
摘要翻译：本申请涉及使用根据通式（I）的异山梨醇醚，其中R'和R“彼此独立地代表氢原子或用于制备洗涤剂和清洁剂的烷基或不饱和烯基部分。 R'和/或R“优选为含有1至33个C原子的直链或支链，饱和或不饱和的烷基或烯基部分。第二个独立的实施方案涉及这些化合物作为水性/表面活性剂组合物的增稠剂的用途。

9. 发明申请

US20120172282A1 Isosorbide Glyceryl Ether Derivatives And Their Use In Household Applications 有权
标题翻译：异山梨醇甘油醚衍生物及其在家庭用途中的应用
公开(公告)号：US20120172282A1
公开(公告)日：2012-07-05
申请号：US13394746
申请日：2010-09-01
申请人： Catherine Breffa , Wolfgang Poly , Ansgar Behler , Thorsten Löhl
发明人： Catherine Breffa , Wolfgang Poly , Ansgar Behler , Thorsten Löhl
IPC分类号： C11D3/20 , A61Q5/02 , A61Q19/10 , C07D493/04 , A61K8/49
CPC分类号： C07D493/04
摘要： Disclosed are isosorbide glyceryl ether derivatives according to the following general formula (I), wherein R or R′ represent a hydrogen atom, or an alkyl or an acyl group with 6 to 22 C-atoms, and n and m represent independent from each other zero, or a number from 1 to 4, and the use thereof in cleansers or detergents or personal care applications.
摘要翻译：公开了根据以下通式（I）的异山梨醇甘油醚衍生物，其中R或R'表示氢原子，或具有6至22个C原子的烷基或酰基，并且n和m彼此独立地表示 0或1至4的数字，以及其在清洁剂或洗涤剂或个人护理应用中的用途。

10. 发明授权

US08420588B2 Isosorbide glyceryl ether derivatives and their use in household applications 有权
标题翻译：异山梨醇甘油醚衍生物及其在家用中的应用
公开(公告)号：US08420588B2
公开(公告)日：2013-04-16
申请号：US13394746
申请日：2010-09-01
申请人： Catherine Breffa , Wolfgang Poly , Ansgar Behler , Thorsten Löhl
发明人： Catherine Breffa , Wolfgang Poly , Ansgar Behler , Thorsten Löhl
IPC分类号： C11D3/20 , C11D3/22 , C11D7/26 , C11D13/10 , B08B3/04
CPC分类号： C07D493/04
摘要： Disclosed are isosorbide glyceryl ether derivatives according to the following general formula (I), wherein R or R′ represent a hydrogen atom, or an alkyl or an acyl group with 6 to 22 C-atoms, and n and m represent independent from each other zero, or a number from 1 to 4, and the use thereof in cleansers or detergents or personal care applications.
摘要翻译：公开了根据以下通式（I）的异山梨醇甘油醚衍生物，其中R或R'表示氢原子，或具有6至22个C原子的烷基或酰基，并且n和m彼此独立地表示 0或1至4的数字，以及其在清洁剂或洗涤剂或个人护理应用中的用途。

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