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1. 发明授权

US08304577B2 Modulators of G protein-coupled receptor 88 有权
标题翻译： G蛋白偶联受体的调节剂88
公开(公告)号：US08304577B2
公开(公告)日：2012-11-06
申请号：US12898016
申请日：2010-10-05
申请人： Carolyn Diane Dzierba , Richard A. Hartz , Yingzhi Bi , Vijay T. Ahuja , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Michael Green , David Kimball , S. Roy Kimura , Soojin Kwon , John E. Macor , Yulian Zhang , Greg Zipp
发明人： Carolyn Diane Dzierba , Richard A. Hartz , Yingzhi Bi , Vijay T. Ahuja , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Michael Green , David Kimball , S. Roy Kimura , Soojin Kwon , John E. Macor , Yulian Zhang , Greg Zipp
IPC分类号： C07C233/00
CPC分类号： C07D207/40 , C07B2200/07 , C07C233/22 , C07C233/40 , C07C237/06 , C07C2601/02 , C07C2601/08 , C07D213/40 , C07D231/12 , C07D277/32
摘要： The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
摘要翻译：本公开一般涉及可以调节G蛋白偶联受体88的化合物，包含这些化合物的组合物，以及调节G蛋白偶联受体88的方法。

2. 发明申请

US20110251196A1 Modulators of G Protein-Coupled Receptor 88 有权
标题翻译： G蛋白偶联受体的调节剂88
公开(公告)号：US20110251196A1
公开(公告)日：2011-10-13
申请号：US12898016
申请日：2010-10-05
申请人： Carolyn Diane Dzierba , Richard A. Hartz , Yingzhi Bi , Vijay T. Ahuja , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Michael Green , David Kimball , S. Roy Kimura , Soojin Kwon , John E. Macor , Yulian Zhang , Greg Zipp
发明人： Carolyn Diane Dzierba , Richard A. Hartz , Yingzhi Bi , Vijay T. Ahuja , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Michael Green , David Kimball , S. Roy Kimura , Soojin Kwon , John E. Macor , Yulian Zhang , Greg Zipp
IPC分类号： A61K31/5375 , A61K31/40 , C07C233/16 , A61K31/165 , C07C233/43 , C07D241/04 , A61K31/495 , C07D265/30 , C07D277/30 , A61K31/426 , C07C237/20 , C07D307/14 , A61K31/341 , C07D213/56 , A61K31/4406 , C07D209/26 , A61K31/4045 , C07D231/12 , A61K31/415 , A61P25/00 , A61P25/18 , A61P25/28 , A61P25/16 , A61P25/36 , C07D207/09
CPC分类号： C07D207/40 , C07B2200/07 , C07C233/22 , C07C233/40 , C07C237/06 , C07C2601/02 , C07C2601/08 , C07D213/40 , C07D231/12 , C07D277/32
摘要： The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
摘要翻译：本公开一般涉及可以调节G蛋白偶联受体88的化合物，包含这些化合物的组合物，以及调节G蛋白偶联受体88的方法。

3. 发明授权

US08497271B2 Modulators of G protein-coupled receptor 88 有权
标题翻译： G蛋白偶联受体的调节剂88
公开(公告)号：US08497271B2
公开(公告)日：2013-07-30
申请号：US12895916
申请日：2010-10-01
申请人： Yingzhi Bi , Carolyn Diane Dzierba , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Li Dong , Cynthia Fink , Michael Green , David Kimball , John E. Macor , Soojin Kwon , Jiancheng Wang , Yulian Zhang , Greg Zipp
发明人： Yingzhi Bi , Carolyn Diane Dzierba , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Li Dong , Cynthia Fink , Michael Green , David Kimball , John E. Macor , Soojin Kwon , Jiancheng Wang , Yulian Zhang , Greg Zipp
IPC分类号： A61K31/496 , A61K31/165 , A61K31/381 , A61P25/16 , A61P25/18 , A61P25/28 , A61P25/30 , C07C233/60 , C07D333/24 , C07D409/12
CPC分类号： C07D333/24 , C07C233/60 , C07C2601/02
摘要： The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.
摘要翻译：本公开一般涉及可以调节G蛋白偶联受体88的化合物，包含这些化合物的组合物，以及调节G蛋白偶联受体88的方法。

4. 发明申请

US20110245264A1 Modulators of G Protein-Coupled Receptor 88 有权
公开(公告)号：US20110245264A1
公开(公告)日：2011-10-06
申请号：US12895916
申请日：2010-10-01
申请人： Yingzhi Bi , Carolyn Diane Dzierba , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Li Dong , Cynthia Fink , Michael Green , David Kimball , John E. Macor , Soojin Kwon , Jiancheng Wang , Yulian Zhang , Greg Zipp
发明人： Yingzhi Bi , Carolyn Diane Dzierba , Joanne J. Bronson , Kenneth Carson , Giovanni Cianchetta , Li Dong , Cynthia Fink , Michael Green , David Kimball , John E. Macor , Soojin Kwon , Jiancheng Wang , Yulian Zhang , Greg Zipp
IPC分类号： A61K31/496 , C07D333/24 , A61K31/381 , C07D409/12 , C07C233/60 , A61K31/165 , A61P25/28 , A61P25/18 , A61P25/16 , A61P25/30
CPC分类号： C07D333/24 , C07C233/60 , C07C2601/02
摘要： The present disclosure is generally directed to compounds which can modulate G-protein coupled receptor 88, compositions comprising such compounds, and methods for modulating G-protein coupled receptor 88.

5. 发明申请

US20060172994A1 Compounds useful as chemokine receptor antagonists 有权
标题翻译：可用作趋化因子受体拮抗剂的化合物
公开(公告)号：US20060172994A1
公开(公告)日：2006-08-03
申请号：US11320414
申请日：2005-12-28
申请人： Kenneth Carson , Prakash Raman , Francois Soucy , Qing Ye , Shomir Ghosh
发明人： Kenneth Carson , Prakash Raman , Francois Soucy , Qing Ye , Shomir Ghosh
IPC分类号： A61K31/55 , A61K31/496 , A61K31/551 , A61K31/454 , C07D403/02
CPC分类号： C07D207/12 , A61K31/454 , A61K31/496 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/52 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D207/14 , C07D211/46 , C07D239/30 , C07D239/86 , C07D239/90 , C07D295/073 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D473/32
摘要： The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer or osteolytic bone disorders.
摘要翻译：本发明涉及可用作趋化因子受体拮抗剂的化合物。提供通式I的化合物：或其药学上可接受的盐。本发明还提供包含所述化合物的药学上可接受的组合物和使用化合物和组合物抑制趋化因子受体的方法，还用于治疗各种疾病，病症或病症，包括急性或慢性炎性疾病，癌症或溶骨性骨骼疾病。

6. 发明申请

US20060106061A1 PGD2 receptor antagonists for the treatment of inflammatory diseases 审中-公开
标题翻译： PGD2受体拮抗剂治疗炎性疾病
公开(公告)号：US20060106061A1
公开(公告)日：2006-05-18
申请号：US11312960
申请日：2005-12-20
申请人： Shomir Ghosh , Amy Elder , Kenneth Carson , Kevin Sprott , Sean Harrison
发明人： Shomir Ghosh , Amy Elder , Kenneth Carson , Kevin Sprott , Sean Harrison
IPC分类号： C07D215/36 , C07D215/38 , A61K31/4706
CPC分类号： C07D471/04 , A61K31/4353 , A61K31/47 , C07D215/42 , C07D215/44 , C07D401/06 , C07D401/10 , C07D401/12 , C07D405/06 , C07D409/06 , C07D413/06 , C07D413/10 , C07D417/06 , C07D491/04 , C07D495/04 , Y02P20/582
摘要： Disclosed herein are compounds represented by Structural Formula (I): (I), wherein the variables are defined herein. Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2 (“CRTH2”) for the treatment of inflammatory disorders.
摘要翻译：本文公开的是由结构式（I）表示的化合物：（I），其中变量在本文中定义。还公开了这样的化合物用于抑制称为Th2（“CRTH2”）表达的化学吸引受体同源分子的G-蛋白偶联受体用于治疗炎症性疾病的用途。

7. 发明授权

US07878476B2 Apparatus for mounting a plurality of monitors having adjustable distance to a viewer 有权
标题翻译：用于安装多个具有可调节距离的监视器的装置
公开(公告)号：US07878476B2
公开(公告)日：2011-02-01
申请号：US11394071
申请日：2006-03-29
申请人： Barry Carson , David Carson , Kenneth Carson
发明人： Barry Carson , David Carson , Kenneth Carson
IPC分类号： F16M13/00
CPC分类号： B60R11/0235 , F16M11/041 , F16M11/14 , F16M11/2085 , F16M13/02 , Y10S248/917 , Y10S248/919 , Y10S248/92 , Y10S248/921
摘要： An apparatus and method for mounting a plurality of display monitors is disclosed, wherein the apparatus is provided at a user's desk or workstation. The apparatus can be easily moved toward and away from the user such that all the monitors mounted on the apparatus move in unison in the direction indicated by the user. Accordingly, the apparatus accommodates the visual preferences of virtually all users of the desk or workstation so that eye and skeletal muscle fatigue are reduced.
摘要翻译：公开了一种用于安装多个显示监视器的装置和方法，其中该设备设置在用户的桌子或工作站。该装置可以容易地朝向和远离用户移动，使得安装在装置上的所有监视器在用户指示的方向上一致地移动。因此，该装置适应桌面或工作站的几乎所有使用者的视觉偏好，从而减少眼睛和骨骼肌疲劳。

8. 发明申请

US20050115556A1 Turkey fryer/outdoor cooker wind and fire guard 审中-公开
标题翻译：土耳其油炸锅/户外灶具风和防火
公开(公告)号：US20050115556A1
公开(公告)日：2005-06-02
申请号：US10726282
申请日：2003-12-01
申请人： Kenneth Carson , Helen Carson
发明人： Kenneth Carson , Helen Carson
IPC分类号： A47J37/00 , A47J37/07
CPC分类号： A47J37/0786
摘要： A wind screen device for an outdoor grill is provided, which comprises a horizontal bottom plate and a series of vertical side plates. The vertical side plates contact each other and the bottom plate to form an enclosure or windscreen. The enclosure is capable of housing a variety of types and sizes of outdoor cooking units, thereby screening out the wind from the outdoor cooking unit. The rigid plates are hooked together by split rings, which are threaded through slotted holes located near the edges of the plates. The side plates are held in place by angled clips when the windscreen device is assembled. The side plates are also capable of being alternately folded down with all of the plates stacked together for storage. The windscreen device includes an additional opening in one of its side plates, which is designed to admit a gas hose therethrough.
摘要翻译：提供一种用于户外格栅的风屏装置，其包括水平底板和一系列垂直侧板。垂直侧板彼此接触和底板形成外壳或挡风玻璃。外壳能够容纳各种类型和大小的户外烹饪单元，从而筛选出户外烹饪单元的风。刚性板通过分开的环钩接在一起，分隔环穿过位于板边缘附近的开槽孔。当挡风玻璃装置组装时，侧板被倾斜的夹子固定在适当的位置。侧板还能够交替地向下折叠，所有的板堆叠在一起用于存储。挡风玻璃装置在其一个侧板中包括一个额外的开口，其设计成允许气体软管通过其中。

9. 发明申请

US20060189628A1 Compounds useful as chemokine receptor antagonists 失效
公开(公告)号：US20060189628A1
公开(公告)日：2006-08-24
申请号：US11320298
申请日：2005-12-28
申请人： Gerard Rosse , Linli Wei , Kenneth Carson
发明人： Gerard Rosse , Linli Wei , Kenneth Carson
IPC分类号： A61K31/496 , A61K31/4545 , C07D403/14 , C07D401/14
CPC分类号： C07D207/14 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D487/08 , C07D491/10
摘要： The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions for the inhibition of Chemokine Receptors and also for the treatment of various diseases, conditions, or disorders, including acute or chronic inflammatory disease, cancer, and osteolytic bone disorders.

10. 发明申请

US20050075348A1 Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor 审中-公开
公开(公告)号：US20050075348A1
公开(公告)日：2005-04-07
申请号：US10983929
申请日：2004-11-08
申请人： Geraldine Harriman , Kenneth Carson , Daniel Flynn , Michael Solomon , Yuntao Song , Bharat Trivedi , Bruce Roth , Christine Kolz , Ly Pham , Kuai-lin Sun
发明人： Geraldine Harriman , Kenneth Carson , Daniel Flynn , Michael Solomon , Yuntao Song , Bharat Trivedi , Bruce Roth , Christine Kolz , Ly Pham , Kuai-lin Sun
IPC分类号： A61P31/18 , C07D209/42 , C07D235/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D487/04 , C07D491/04 , C07D491/08 , A61K31/519 , A61K31/52 , A61K31/53
CPC分类号： C07D401/04 , C07D209/42 , C07D235/26 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D487/04 , C07D491/04 , C07D491/08
摘要： Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.

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