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1. 发明申请

US20090202430A1 COMPOSITION FOR CYTOCOMPATIBLE, INJECTABLE, SELF-GELLING POLYSACCHARIDE SOLUTIONS FOR ENCAPSULATING AND DELIVERING LIVE CELLS OR BIOLOGICALLY ACTIVE FACTORS 审中-公开
标题翻译：用于包埋和递送活细胞或生物活性因子的可注射的，可注射的，自凝胶多糖溶液的组合物
公开(公告)号：US20090202430A1
公开(公告)日：2009-08-13
申请号：US12423156
申请日：2009-04-14
申请人： Caroline Hoemann , Abdellatif Chenite , Michael Buschmann , Alessio Serreqi , Jun Sun
发明人： Caroline Hoemann , Abdellatif Chenite , Michael Buschmann , Alessio Serreqi , Jun Sun
IPC分类号： A61K51/00 , A61K35/12 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K38/43 , A61K9/127 , A61K39/12 , A61K35/14
CPC分类号： A61L27/3604 , A01N1/0205 , A01N1/021 , A01N1/0231 , A61K9/0024 , A61K31/717 , A61L27/20 , A61L27/3641 , A61L27/365 , A61L27/3654 , A61L27/3839 , A61L27/3847 , A61L27/3852 , A61L27/50 , A61L27/52 , C08L5/08
摘要： The present invention provides compositions and methods for tissue repair using a cytocompatible self-gelling cross-linked hydrogel. The composition comprises a biocompatible mixture of chitosan, bifunctional dialdehyde, and hydroxylated polymer, which can be used to immobilize or encapsulate viable cells, or bioactive substances. The method includes the process of mixing bioactive substances, live cells, and/or extracellular matrix components with a cross-linking solution comprising a bifunctional aldehyde-treated hydroxylated polymer such as hydroxyethyl cellulose. The cross-linking solution is then mixed homogenously with a neutral isotonic chitosan solution. The chitosan becomes cross-linked by the bifunctional aldehyde, while the cells are protected from potentially nocive effects of the aldehyde cross-linker by the hydroxylated polymer. The injectable solution retains cell viability and bioactivity, and immobilizes cells at the site of injection or delivery. Depending on the particular application, mixtures of chitosan and bifunctional dialdehyde may be employed. The injectable solution also liberates bioactive substances with controlled release kinetics from the site of injection.
摘要翻译：本发明提供使用细胞相容性自凝胶交联水凝胶进行组织修复的组合物和方法。该组合物包含壳聚糖，双功能二醛和羟基化聚合物的生物相容性混合物，其可用于固定或包囊活细胞或生物活性物质。该方法包括将生物活性物质，活细胞和/或细胞外基质组分与包含双官能醛处理的羟基化聚合物如羟乙基纤维素的交联溶液混合的方法。然后将交联溶液与中性等渗壳聚糖溶液均匀混合。壳聚糖通过双官能醛交联，同时保护细胞免受羟基化聚合物对醛交联剂的潜在的伤害作用。注射溶液保留细胞活力和生物活性，并将细胞固定在注射或递送部位。根据具体应用，可以使用壳聚糖和双官能二醛的混合物。注射溶液也释放出具有从注射部位释放动力学的生物活性物质。

2. 发明申请

US20060127873A1 Composition for cytocompatible, injectable, self-gelling chitosan solutions for encapsulating and delivering live cells or biologically active factors 审中-公开
标题翻译：用于包封和递送活细胞或生物活性因子的细胞相容性，可注射的自凝胶壳聚糖溶液的组成
公开(公告)号：US20060127873A1
公开(公告)日：2006-06-15
申请号：US10521524
申请日：2003-07-16
申请人： Caroline Hoemann , Abdellatif Chenite , Michael Buschmann , Alessio Sarreqi , Jun Sun
发明人： Caroline Hoemann , Abdellatif Chenite , Michael Buschmann , Alessio Sarreqi , Jun Sun
IPC分类号： A01N1/02 , C12N5/06 , A61K31/717
CPC分类号： A61L27/3604 , A01N1/0205 , A01N1/021 , A01N1/0231 , A61K9/0024 , A61K31/717 , A61L27/20 , A61L27/3641 , A61L27/365 , A61L27/3654 , A61L27/3839 , A61L27/3847 , A61L27/3852 , A61L27/50 , A61L27/52 , C08L5/08
摘要： The present invention provides compositions and methods for tissue repair using a cytocompatible self-gelling cross-linked hydrogel. The composition comprises a biocompatible mixture of chitosan, bifunctional dialdehyde, and hydroxylated polymer, which can be used to immobilize or encapsulate viable cells, or bioactive substances. The method includes the process of mixing bioactive substances, live cells, and/or extracellular matrix components with a cross-linking solution comprising a bifunctional aldehyde-treated hydroxylated polymer such as hydroxyethyl cellulose. The cross-linking solution is then mixed homogenously with a neutral isotonic chitosan solution. The chitosan becomes cross-linked by the bifunctional aldehyde, while the cells are protected from potentially nocive effects of the aldehyde cross-linker by the hydroxylated polymer. The injectable solution retains cell viability and bioactivity, and immobilizes cells at the site of injection or delivery. Depending on the particular application, mixtures of chitosan and bifunctional dialdehyde may be employed. The injectable solution also liberates bioactive substances with controlled release kinetics from the site of injection.
摘要翻译：本发明提供使用细胞相容性自凝胶交联水凝胶进行组织修复的组合物和方法。该组合物包含壳聚糖，双功能二醛和羟基化聚合物的生物相容性混合物，其可用于固定或包囊活细胞或生物活性物质。该方法包括将生物活性物质，活细胞和/或细胞外基质组分与包含双官能醛处理的羟基化聚合物如羟乙基纤维素的交联溶液混合的方法。然后将交联溶液与中性等渗壳聚糖溶液均匀混合。壳聚糖通过双官能醛交联，同时保护细胞免受羟基化聚合物对醛交联剂的潜在的伤害作用。注射溶液保留细胞活力和生物活性，并将细胞固定在注射或递送部位。根据具体应用，可以使用壳聚糖和双官能二醛的混合物。注射溶液也释放出具有从注射部位释放动力学的生物活性物质。

3. 外观设计

USD1035158S1 Artificial lash extension 有权
公开(公告)号：USD1035158S1
公开(公告)日：2024-07-09
申请号：US29934805
申请日：2024-03-27
申请人： Jun Sun
设计人： Jun Sun
摘要： FIG. 1 is a front, left and top perspective view of a artificial lash extension, showing my design.
FIG. 2 is a front elevation view thereof.
FIG. 3 is a rear elevation view thereof.
FIG. 4 is a left side elevation view thereof.
FIG. 5 is a right side elevation view thereof.
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.

4. 外观设计

USD986478S1 Lamp head 有权
公开(公告)号：USD986478S1
公开(公告)日：2023-05-16
申请号：US29862589
申请日：2022-12-09
申请人： Jun Sun
设计人： Jun Sun
摘要： FIG. 1 is a front, right and top perspective view of a lamp head, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof.
FIG. 8 is a bottom plan view thereof; and,
FIG. 9 is another front, right and top perspective view of the lamp head in a usable state.
The broken lines depicting portions of the lamp head form no part of the claimed design. The broken line bulb and hanger bar in FIG. 9 depict environmental structure that form no part of the claimed design.

5. 发明授权

US09175297B2 Microorganisms for the production of 1,4-Butanediol 有权
标题翻译：用于生产1,4-丁二醇的微生物
公开(公告)号：US09175297B2
公开(公告)日：2015-11-03
申请号：US13449187
申请日：2012-04-17
申请人： Mark J. Burk , Anthony P. Burgard , Robin E. Osterhout , Jun Sun
发明人： Mark J. Burk , Anthony P. Burgard , Robin E. Osterhout , Jun Sun
IPC分类号： C12P7/18 , C12N9/04 , C12N9/88 , C12N9/90 , C12N15/52 , C12N15/70 , C12N15/81
CPC分类号： C12P7/18 , B01D3/002 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/1096 , C12N9/12 , C12N9/13 , C12N9/16 , C12N9/88 , C12N9/90 , C12N9/93 , C12N15/52 , C12N15/70 , C12N15/81 , C12Y101/01157 , C12Y402/01055
摘要： The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO. The invention additionally provides methods of using such microbial organisms to produce BDO.
摘要翻译：本发明提供包含1,4-丁二醇（BDO）途径的非天然存在的微生物生物，该途径包含至少一种编码足够数量产生BDO的BDO途径酶的外源核酸。本发明还提供了使用这种微生物生产BDO的方法。

6. 发明授权

US09077926B2 Image processing method and image processing apparatus 有权
标题翻译：图像处理方法和图像处理装置
公开(公告)号：US09077926B2
公开(公告)日：2015-07-07
申请号：US13490841
申请日：2012-06-07
申请人： Yuan He , Jun Sun , Hao Yu , Satoshi Naoi
发明人： Yuan He , Jun Sun , Hao Yu , Satoshi Naoi
IPC分类号： G06K9/48 , H04N1/387
CPC分类号： H04N1/387
摘要： An image processing method includes estimating corners of a contour of an object area in an obtained image, searching for contour lines of the object area between every two points which are offset from the estimated corners within a predetermined degree or distance along a direction away from the object area respectively, and determining intersection points of the contour lines as final corners of the contour of the object area, and determining contour lines between the final corners as a final contour of the object area.
摘要翻译：一种图像处理方法，包括估计所获得的图像中的对象区域的轮廓的角，在沿着远离所述图像的方向的预定角度或距离内的估计角落偏移的每两个点之间搜索对象区域的轮廓线并且将轮廓线的交点确定为对象区域的轮廓的最终角，并且确定最终角之间的轮廓线作为对象区域的最终轮廓。

7. 发明申请

US20140325625A1 CYBER GENE IDENTIFICATION TECHNOLOGY BASED ON ENTITY FEATURES IN CYBER SPACE 有权
标题翻译：基于CYBER空间实体特征的CYBER基因鉴定技术
公开(公告)号：US20140325625A1
公开(公告)日：2014-10-30
申请号：US14326164
申请日：2014-07-08
申请人： Nanjie Liu , Jun Sun , Haitao Zhao , Chengjie Gu , Dapeng Li
发明人： Nanjie Liu , Jun Sun , Haitao Zhao , Chengjie Gu , Dapeng Li
IPC分类号： H04L29/06 , H04W12/06
CPC分类号： H04L63/083 , H04L29/12207 , H04L29/12716 , H04L61/20 , H04L61/3065 , H04L63/08 , H04L63/20 , H04L67/303 , H04W12/06
摘要： A new identification (ID) technology comprising unified and standardized object identification within Cyber Space is disclosed based upon intrinsic properties of the entity to be identified. This Cyber Gene ID (or Cyber ID) technology extracts intrinsic information from either the physical users or their cyberspace counterparts, and such information is categorized into client parameters, dynamic parameters, static parameters, cloud parameters, connection parameters and user parameters.
摘要翻译：基于要识别的实体的固有属性，公开了一种包括网络空间内统一标准化对象识别的新标识（ID）技术。该网络基因ID（或Cyber ID）技术从物理用户或其网络空间对等体中提取固有信息，并将这些信息分为客户端参数，动态参数，静态参数，云参数，连接参数和用户参数。

8. 发明授权

US08715971B2 Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol 有权
标题翻译：用于共同生产异丙醇和1,4-丁二醇的微生物和方法
公开(公告)号：US08715971B2
公开(公告)日：2014-05-06
申请号：US12878980
申请日：2010-09-09
申请人： Priti Pharkya , Anthony P. Burgard , Robin E. Osterhout , Mark J. Burk , Jun Sun
发明人： Priti Pharkya , Anthony P. Burgard , Robin E. Osterhout , Mark J. Burk , Jun Sun
IPC分类号： C12P7/04
CPC分类号： C12P7/40 , C12N15/52 , C12P7/04 , C12P7/18
摘要： The invention provides a non-naturally occurring microbial organism having n-propanol and isopropanol pathways, 1,4-butanediol (14-BDO) and isopropanol pathways, 1,3-butanediol (13-BDO) and isopropanol pathways or methylacrylic acid (MAA) and isopropanolpathways. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in each of the respective n-propanol, 14-BDO, 13-BDO or MAA and isopropanol pathways. The invention additionally provides a method for co-producing n-propanol and isopropanol, 14-BDO and isopropanol, 13-BDO and isopropanol or MAA and isopropanol. The method can include culturing an n-propanol and an isopropanol co-producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an n-propanol, an isopropanol, a 14-BDO, a 13-BDO and/or a MAA pathway enzyme in a sufficient amount to produce each of the respective products, under conditions and for a sufficient period of time to produce each of the respective products.
摘要翻译：本发明提供了具有正丙醇和异丙醇途径的非天然存在的微生物生物，1,4-丁二醇（14-BDO）和异丙醇途径，1,3-丁二醇（13-BDO）和异丙醇途径或甲基丙烯酸（MAA ）和异丙醇通道。微生物生物体含有至少一种外源核酸，其编码在各自的正丙醇，14-BDO，13-BDO或MAA和异丙醇途径中的酶。本发明另外提供了共同生产正丙醇和异丙醇，14-BDO和异丙醇，13-BDO和异丙醇或MAA和异丙醇的方法。该方法可以包括培养正丙醇和异丙醇共同生产的微生物，其中微生物生物体表达至少一种编码正丙醇，异丙醇，14-BDO，13-BDO和/或足够量的MAA途径酶，以在条件下和足够的时间内产生各个产物中的每一种以产生各个产物。

9. 发明授权

US08623196B2 Nanostructured biosensor containing neuropathy target esterase activity 有权
标题翻译：含有神经病目标酯酶活性的纳米结构生物传感器
公开(公告)号：US08623196B2
公开(公告)日：2014-01-07
申请号：US12121389
申请日：2008-05-15
申请人： Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
发明人： Neeraj Kohli , Devesh Srivastava , Rudy J. Richardson , Jun Sun , Ilsoon Lee , Robert M. Worden
IPC分类号： G01N27/327
CPC分类号： G01N27/127
摘要： The present invention provides compositions, devices and methods for detecting esterase activity. The present invention also provides devices and methods of detecting esterase inhibitors, for example, organophosphates. In particular, the present invention provides a biosensor comprising Neuropathy Target Esterase (NTE) polypeptides. Further, the present invention relates to medicine, industrial chemistry, agriculture, and homeland security.
摘要翻译：本发明提供了用于检测酯酶活性的组合物，装置和方法。本发明还提供了检测酯酶抑制剂例如有机磷酸酯的装置和方法。特别地，本发明提供了包含神经病目标酯酶（NTE）多肽的生物传感器。此外，本发明涉及医药，工业化学，农业和国土安全。

10. 发明授权

US08617862B2 Microorganisms for producing propylene and methods related thereto 有权
标题翻译：用于生产丙烯的微生物及其相关方法
公开(公告)号：US08617862B2
公开(公告)日：2013-12-31
申请号：US13527455
申请日：2012-06-19
申请人： Anthony P. Burgard , Robin E. Osterhout , Jun Sun , Priti Pharkya , Mark J. Burk
发明人： Anthony P. Burgard , Robin E. Osterhout , Jun Sun , Priti Pharkya , Mark J. Burk
IPC分类号： C12P5/02 , C12P5/00 , C12P1/04
CPC分类号： C12P5/026 , C12N1/20 , C12N9/0004 , C12N9/1007
摘要： The invention provides non-naturally occurring microbial organisms having a propylene pathway. The invention additionally provides methods of using such organisms to produce propylene.
摘要翻译：本发明提供具有丙烯途径的非天然存在的微生物。本发明另外提供了使用这些生物来生产丙烯的方法。

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